Trim27 (tripartite motif containing 27) - Rat Genome Database

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Gene: Trim27 (tripartite motif containing 27) Heterocephalus glaber
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Symbol: Trim27
Name: tripartite motif containing 27
RGD ID: 18903855
Description: ENCODES a protein that exhibits identical protein binding (ortholog); SUMO transferase activity (ortholog); transcription coactivator activity (ortholog); INVOLVED IN Arp2/3 complex-mediated actin nucleation (ortholog); innate immune response (ortholog); negative regulation of adaptive immune response (ortholog); ASSOCIATED WITH megacolon (ortholog); FOUND IN cytoplasm (ortholog); endosome (ortholog); fibrillar center (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Zinc finger protein RFP
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475624,897,206 - 24,908,478 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475624,897,206 - 24,908,449 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
megacolon  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Trim27
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475624,897,206 - 24,908,478 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475624,897,206 - 24,908,449 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TRIM27
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38628,903,002 - 28,923,985 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl628,903,002 - 28,923,988 (-)EnsemblGRCh38hg38GRCh38
GRCh37628,870,779 - 28,891,762 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36628,978,758 - 28,999,747 (-)NCBINCBI36Build 36hg18NCBI36
Build 34628,978,758 - 28,999,744NCBI
Celera630,476,904 - 30,497,881 (-)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef628,678,679 - 28,699,726 (-)NCBIHuRef
CHM1_1628,873,036 - 28,894,024 (-)NCBICHM1_1
T2T-CHM13v2.0628,777,794 - 28,798,769 (-)NCBIT2T-CHM13v2.0
Trim27
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391321,363,570 - 21,378,893 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1321,363,615 - 21,378,894 (+)EnsemblGRCm39 Ensembl
GRCm381321,179,450 - 21,194,723 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1321,179,445 - 21,194,724 (+)EnsemblGRCm38mm10GRCm38
MGSCv371321,271,828 - 21,284,726 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361321,187,827 - 21,200,322 (+)NCBIMGSCv36mm8
Celera1321,444,935 - 21,457,832 (+)NCBICelera
Cytogenetic Map13A3.1NCBI
cM Map137.67NCBI
Trim27
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81748,233,999 - 48,246,348 (-)NCBIGRCr8
mRatBN7.21743,538,282 - 43,550,633 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1743,538,285 - 43,550,643 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1745,602,338 - 45,614,707 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01750,361,433 - 50,373,802 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01744,845,531 - 44,857,874 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01745,613,863 - 45,626,212 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1745,613,864 - 45,626,212 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01757,844,089 - 57,856,503 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41751,192,286 - 51,204,942 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11751,195,447 - 51,214,144 (-)NCBI
Celera1752,928,787 - 52,941,136 (+)NCBICelera
Cytogenetic Map17q11NCBI
Trim27
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546513,890,900 - 13,903,016 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546513,891,001 - 13,902,767 (-)NCBIChiLan1.0ChiLan1.0
TRIM27
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2543,536,777 - 43,558,608 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1639,537,301 - 39,558,344 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0628,722,505 - 28,743,484 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1629,390,423 - 29,411,308 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl629,390,423 - 29,411,308 (-)Ensemblpanpan1.1panPan2
TRIM27
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13525,904,381 - 25,922,531 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3525,905,396 - 25,923,336 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3525,777,587 - 25,795,612 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03526,199,826 - 26,217,843 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3526,199,828 - 26,217,885 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13525,862,428 - 25,880,441 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03525,918,116 - 25,936,647 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03527,389,980 - 27,408,261 (-)NCBIUU_Cfam_GSD_1.0
Trim27
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494629,181,649 - 29,203,486 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936914245,283 - 263,435 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936914245,348 - 263,060 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM27
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.2724,432,798 - 24,451,382 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRIM27
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11743,647,965 - 43,670,945 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1743,647,951 - 43,670,978 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604428,591,242 - 28,614,234 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000011329   ⟹   ENSHGLP00000011204
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475624,897,206 - 24,908,478 (-)Ensembl
RefSeq Acc Id: XM_004847850   ⟹   XP_004847907
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475624,897,206 - 24,908,449 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004847907 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB16306 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000011204
RefSeq Acc Id: XP_004847907   ⟸   XM_004847850
- UniProtKB: G5C445 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000011204   ⟸   ENSHGLT00000011329


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000008037 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000011329 ENTREZGENE
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  Zinc/RING finger domain, C3HC4 (zinc finger) UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/TrEMBL
  Butyrophylin_SPRY UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/TrEMBL
  PRY UniProtKB/TrEMBL
  SPRY/PRY_TRIM27 UniProtKB/TrEMBL
  SPRY_dom UniProtKB/TrEMBL
  TRIM/RBCC UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
NCBI Gene Trim27 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE TRIM UniProtKB/TrEMBL
  ZINC FINGER PROTEIN RFP UniProtKB/TrEMBL
Pfam PRY UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
  zf-C3HC4_4 UniProtKB/TrEMBL
PRINTS BUTYPHLNCDUF UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART PRY UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
Superfamily-SCOP Concanavalin A-like lectins/glucanases UniProtKB/TrEMBL
  RING/U-box UniProtKB/TrEMBL
UniProt G5C445 ENTREZGENE, UniProtKB/TrEMBL