Ltn1 (listerin E3 ubiquitin protein ligase 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Ltn1 (listerin E3 ubiquitin protein ligase 1) Heterocephalus glaber
Analyze
Symbol: Ltn1
Name: listerin E3 ubiquitin protein ligase 1
RGD ID: 18902049
Description: ENCODES a protein that exhibits ubiquitin-protein transferase activity (ortholog); INVOLVED IN protein autoubiquitination (ortholog); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN cytosolic ribosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase listerin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474516,936,987 - 16,988,519 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474516,939,183 - 16,988,438 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ltn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474516,936,987 - 16,988,519 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474516,939,183 - 16,988,438 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
LTN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382128,928,144 - 28,992,877 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2128,928,144 - 28,992,956 (-)EnsemblGRCh38hg38GRCh38
GRCh372130,300,466 - 30,365,198 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362129,222,337 - 29,287,095 (-)NCBINCBI36Build 36hg18NCBI36
Build 342129,222,336 - 29,287,095NCBI
Celera2115,483,199 - 15,548,010 (-)NCBICelera
Cytogenetic Map21q21.3NCBI
HuRef2115,705,158 - 15,769,951 (-)NCBIHuRef
CHM1_12129,862,811 - 29,927,624 (-)NCBICHM1_1
T2T-CHM13v2.02127,290,835 - 27,355,596 (-)NCBIT2T-CHM13v2.0
Ltn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391687,173,539 - 87,229,504 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1687,173,539 - 87,229,500 (-)EnsemblGRCm39 Ensembl
GRCm381687,376,651 - 87,432,619 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1687,376,651 - 87,432,612 (-)EnsemblGRCm38mm10GRCm38
MGSCv371687,376,896 - 87,432,851 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361687,265,847 - 87,321,802 (-)NCBIMGSCv36mm8
MGSCv361688,001,029 - 88,057,566 (-)NCBIMGSCv36mm8
Celera1687,558,856 - 87,624,942 (-)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1649.52NCBI
Ltn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81140,090,169 - 40,147,159 (-)NCBIGRCr8
mRatBN7.21126,603,903 - 26,660,871 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1126,603,903 - 26,660,886 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1135,301,730 - 35,358,731 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01128,001,977 - 28,058,974 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01127,190,910 - 27,247,908 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01127,023,328 - 27,080,575 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1127,022,986 - 27,080,701 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01130,648,567 - 30,706,023 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41127,126,258 - 27,184,111 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11127,126,258 - 27,134,341 (-)NCBI
Celera1126,356,355 - 26,413,197 (-)NCBICelera
Cytogenetic Map11q11NCBI
Ltn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540728,301,636 - 28,352,797 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540728,303,598 - 28,352,797 (-)NCBIChiLan1.0ChiLan1.0
LTN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22225,109,514 - 25,174,624 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12119,968,137 - 20,033,245 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02115,359,090 - 15,424,126 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12128,747,271 - 28,812,744 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2128,749,584 - 28,812,734 (-)Ensemblpanpan1.1panPan2
LTN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13123,942,493 - 24,008,787 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3123,944,611 - 24,008,917 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3123,935,054 - 24,002,104 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03124,054,956 - 24,122,763 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3124,054,957 - 24,122,660 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13124,006,096 - 24,073,139 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03124,007,941 - 24,074,805 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03124,479,423 - 24,546,297 (-)NCBIUU_Cfam_GSD_1.0
Ltn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497124,406,797 - 24,453,685 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650013,014,102 - 13,061,699 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650013,014,102 - 13,061,695 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LTN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13192,295,766 - 192,358,717 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113192,295,764 - 192,358,762 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213202,598,643 - 202,660,954 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LTN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1263,226,810 - 63,291,646 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl263,226,862 - 63,293,507 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660715,812,025 - 5,879,459 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000007054   ⟹   ENSHGLP00000006970
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474516,936,987 - 16,988,519 (-)Ensembl
RefSeq Acc Id: XM_004842245   ⟹   XP_004842302
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474516,939,183 - 16,988,438 (-)NCBI
RefSeq Acc Id: XM_021256134   ⟹   XP_021111793
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474516,939,183 - 16,980,234 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004842302 (Get FASTA)   NCBI Sequence Viewer  
  XP_021111793 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000006970
RefSeq Acc Id: XP_004842302   ⟸   XM_004842245
- Peptide Label: isoform X1
- UniProtKB: A0AAX6P2N0 (UniProtKB/TrEMBL),   G5B1C2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021111793   ⟸   XM_021256134
- Peptide Label: isoform X2
- UniProtKB: A0AAX6SVF1 (UniProtKB/TrEMBL),   G5B1C2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000006970   ⟸   ENSHGLT00000007054


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000005092 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000007054 ENTREZGENE
Gene3D-CATH Leucine-rich Repeat Variant UniProtKB/TrEMBL
  Zinc/RING finger domain, C3HC4 (zinc finger) UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  LTN1/Rkr1 UniProtKB/TrEMBL
  LTN1_E3_ligase_6th UniProtKB/TrEMBL
  Ltn1_N UniProtKB/TrEMBL
  LTN1_UBC UniProtKB/TrEMBL
  RING-CH-C4HC3_LTN1 UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING-CH UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene Ltn1 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE LISTERIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 294 UniProtKB/TrEMBL
Pfam Ltn1_1st UniProtKB/TrEMBL
  LTN1_E3_ligase_6th UniProtKB/TrEMBL
  UBC_like UniProtKB/TrEMBL
  zf-RING_2 UniProtKB/TrEMBL
PROSITE ZF_RING_2 UniProtKB/TrEMBL
SMART RINGv UniProtKB/TrEMBL
Superfamily-SCOP ARM repeat UniProtKB/TrEMBL
  RING/U-box UniProtKB/TrEMBL
UniProt A0AAX6P2N0 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SVF1 ENTREZGENE, UniProtKB/TrEMBL
  G5B1C2 ENTREZGENE, UniProtKB/TrEMBL