Trmt112 (tRNA methyltransferase activator subunit 11-2) - Rat Genome Database

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Gene: Trmt112 (tRNA methyltransferase activator subunit 11-2) Heterocephalus glaber
Analyze
Symbol: Trmt112
Name: tRNA methyltransferase activator subunit 11-2 (Ensembl:tRNA methyltransferase subunit 11-2)
RGD ID: 18900995
Description: ENCODES a protein that exhibits protein methyltransferase activity (ortholog); tRNA methyltransferase activator activity (ortholog); INVOLVED IN positive regulation of rRNA processing (ortholog); rRNA methylation (ortholog); transcription initiation-coupled chromatin remodeling (ortholog); ASSOCIATED WITH high grade glioma (ortholog); intellectual disability (ortholog); leukocyte adhesion deficiency 3 (ortholog); FOUND IN nucleoplasm (ortholog); perinuclear region of cytoplasm (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: multifunctional methyltransferase subunit TRM112-like protein; TRM112-like protein; tRNA methyltransferase 11-2 homolog; tRNA methyltransferase 112 homolog; tRNA methyltransferase subunit 11-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476721,998,812 - 21,999,984 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476721,998,839 - 21,999,984 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Trmt112
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476721,998,812 - 21,999,984 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476721,998,839 - 21,999,984 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TRMT112
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381164,316,460 - 64,318,596 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1164,316,460 - 64,317,559 (-)EnsemblGRCh38hg38GRCh38
GRCh371164,083,932 - 64,086,068 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361163,840,739 - 63,841,609 (-)NCBINCBI36Build 36hg18NCBI36
Celera1161,410,247 - 61,411,117 (-)NCBICelera
Cytogenetic Map11q13.1NCBI
HuRef1160,411,904 - 60,412,774 (-)NCBIHuRef
CHM1_11163,967,176 - 63,968,046 (-)NCBICHM1_1
T2T-CHM13v2.01164,306,441 - 64,308,577 (-)NCBIT2T-CHM13v2.0
Trmt112
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39196,887,066 - 6,888,396 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl196,887,066 - 6,888,417 (+)EnsemblGRCm39 Ensembl
GRCm38196,909,698 - 6,911,028 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl196,909,698 - 6,911,049 (+)EnsemblGRCm38mm10GRCm38
MGSCv37196,984,188 - 6,985,518 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36196,976,742 - 6,978,066 (+)NCBIMGSCv36mm8
Celera196,686,479 - 6,687,807 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map195.08NCBI
Trmt112
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81213,532,507 - 213,533,360 (+)NCBIGRCr8
mRatBN7.21204,103,298 - 204,104,151 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1212,453,495 - 212,454,348 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01219,548,562 - 219,549,415 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01212,239,614 - 212,240,467 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01222,167,927 - 222,168,780 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1222,167,927 - 222,168,776 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01229,158,781 - 229,159,634 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41209,586,879 - 209,587,732 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11209,745,335 - 209,745,991 (+)NCBI
Celera1201,637,246 - 201,638,099 (+)NCBICelera
Cytogenetic Map1q43NCBI
Trmt112
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542220,767,599 - 20,768,505 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542220,767,599 - 20,768,505 (+)NCBIChiLan1.0ChiLan1.0
TRMT112
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2965,543,781 - 65,544,989 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11166,588,926 - 66,590,308 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01159,673,737 - 59,675,005 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11163,018,695 - 63,020,086 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1163,018,695 - 63,020,086 (-)Ensemblpanpan1.1panPan2
TRMT112
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11852,754,379 - 52,755,596 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1852,754,721 - 52,755,730 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1851,361,404 - 51,362,668 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01853,799,745 - 53,801,009 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1853,800,134 - 53,801,143 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11852,891,593 - 52,892,856 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01852,478,181 - 52,479,445 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01853,262,059 - 53,263,323 (+)NCBIUU_Cfam_GSD_1.0
Trmt112
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049478,455,228 - 8,456,221 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365994,897,324 - 4,898,586 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365994,897,394 - 4,898,618 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRMT112
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl27,802,275 - 7,803,552 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.127,802,184 - 7,803,556 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.226,868,003 - 6,869,375 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRMT112
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.119,916,884 - 9,918,790 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666038107,257,830 - 107,259,221 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000015714   ⟹   ENSHGLP00000015550
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476721,998,812 - 21,999,984 (+)Ensembl
RefSeq Acc Id: XM_004852514   ⟹   XP_004852571
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476721,998,839 - 21,999,984 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004852571 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB04925 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000015550
  ENSHGLP00100019253
GenBank Protein JAO03480 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004852571   ⟸   XM_004852514
- UniProtKB: G5B6P8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000015550   ⟸   ENSHGLT00000015714


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000011130 Ensembl, ENTREZGENE
  ENSHGLG00100014193 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000015714 ENTREZGENE
  ENSHGLT00100019452 UniProtKB/TrEMBL
Gene3D-CATH 2.20.25.10 UniProtKB/TrEMBL
InterPro Trm112 UniProtKB/TrEMBL
  Trm112-like UniProtKB/TrEMBL
KEGG Report hgl:101725683 UniProtKB/TrEMBL
NCBI Gene Trmt112 ENTREZGENE
PANTHER MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN UniProtKB/TrEMBL
  PTHR12773 UniProtKB/TrEMBL
Pfam Trm112p UniProtKB/TrEMBL
Superfamily-SCOP Trm112p-like UniProtKB/TrEMBL
UniProt G5B6P8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-04-27 Trmt112  tRNA methyltransferase activator subunit 11-2  Trmt112  tRNA methyltransferase subunit 11-2  Symbol and/or name change 5135510 APPROVED