Rnls (renalase, FAD dependent amine oxidase) - Rat Genome Database

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Gene: Rnls (renalase, FAD dependent amine oxidase) Heterocephalus glaber
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Symbol: Rnls
Name: renalase, FAD dependent amine oxidase
RGD ID: 18899635
Description: ENCODES a protein that exhibits epinephrine binding (ortholog); monoamine oxidase activity (ortholog); NADH binding (ortholog); INVOLVED IN cardiac left ventricle morphogenesis (ortholog); dopamine metabolic process (ortholog); epinephrine metabolic process (ortholog); ASSOCIATED WITH autoimmune lymphoproliferative syndrome (ortholog); chronic kidney disease (ortholog); congestive heart failure (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: renalase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462479114,542,625 - 14,873,393 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Rnls
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462479114,542,625 - 14,873,393 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RNLS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381088,171,523 - 88,583,318 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1088,273,864 - 88,584,530 (-)EnsemblGRCh38hg38GRCh38
GRCh371090,033,619 - 90,343,075 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361090,023,601 - 90,332,988 (-)NCBINCBI36Build 36hg18NCBI36
Build 341090,023,600 - 90,332,988NCBI
Celera1083,780,492 - 84,089,897 (-)NCBICelera
Cytogenetic Map10q23.31NCBI
HuRef1083,668,375 - 83,977,653 (-)NCBIHuRef
CHM1_11090,315,752 - 90,625,158 (-)NCBICHM1_1
T2T-CHM13v2.01089,050,656 - 89,467,392 (-)NCBIT2T-CHM13v2.0
Rnls
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391933,115,140 - 33,369,695 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1933,115,147 - 33,369,665 (-)EnsemblGRCm39 Ensembl
GRCm381933,137,740 - 33,392,295 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1933,137,747 - 33,392,295 (-)EnsemblGRCm38mm10GRCm38
MGSCv371933,212,234 - 33,466,785 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361933,203,744 - 33,458,836 (-)NCBIMGSCv36mm8
Celera1933,919,313 - 34,173,994 (-)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1929.08NCBI
Rnls
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81240,450,702 - 240,723,472 (-)NCBIGRCr8
mRatBN7.21231,037,481 - 231,309,855 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1231,037,486 - 231,309,823 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1239,414,353 - 239,688,126 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01246,344,061 - 246,617,558 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01239,182,149 - 239,455,647 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01251,828,285 - 252,101,963 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1251,828,290 - 252,100,759 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01259,052,388 - 259,324,901 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41237,364,578 - 237,639,800 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11237,528,600 - 237,803,823 (-)NCBI
Celera1228,151,441 - 228,423,443 (-)NCBICelera
Cytogenetic Map1q52NCBI
Rnls
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554254,368,620 - 4,667,947 (+)NCBIChiLan1.0ChiLan1.0
RNLS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28100,195,947 - 100,598,256 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110100,201,262 - 100,603,822 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01084,996,999 - 85,304,240 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11088,502,588 - 88,809,439 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1088,503,683 - 88,808,990 (-)Ensemblpanpan1.1panPan2
RNLS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12638,137,662 - 38,413,666 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2638,083,371 - 38,414,033 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2637,955,732 - 38,233,014 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02639,670,571 - 40,000,185 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2639,702,516 - 40,000,302 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12637,574,898 - 37,840,447 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02637,159,099 - 37,435,881 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02638,428,192 - 38,705,871 (-)NCBIUU_Cfam_GSD_1.0
Rnls
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721377,744,737 - 78,131,700 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936735659,826 - 1,048,135 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNLS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14100,317,625 - 100,605,063 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114100,312,592 - 100,604,953 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214109,298,823 - 109,589,104 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RNLS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1981,725,115 - 82,029,361 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604842,407,027 - 42,707,316 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004858346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004858347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004858348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01065789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01065790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01065791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01065792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01065793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01065794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01065795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01065796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01065797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01065798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01065799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01065800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01065801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01065802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01065803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01065804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01065805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01065806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01065807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01003779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_004858346   ⟹   XP_004858403
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479114,542,625 - 14,873,392 (-)NCBI
RefSeq Acc Id: XM_004858347   ⟹   XP_004858404
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479114,567,961 - 14,873,393 (-)NCBI
RefSeq Acc Id: XM_004858348   ⟹   XP_004858405
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479114,542,625 - 14,873,393 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004858403 (Get FASTA)   NCBI Sequence Viewer  
  XP_004858404 (Get FASTA)   NCBI Sequence Viewer  
  XP_004858405 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00100028423
GenBank Protein JAN99853 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004858405   ⟸   XM_004858348
- Peptide Label: isoform X3
RefSeq Acc Id: XP_004858403   ⟸   XM_004858346
- Peptide Label: isoform X1
- UniProtKB: A0A0N8ETP8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004858404   ⟸   XM_004858347
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00100011677 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00100086068 UniProtKB/TrEMBL
Gene3D-CATH 3.50.50.60 UniProtKB/TrEMBL
  3.90.660.10 UniProtKB/TrEMBL
InterPro Amino_oxidase UniProtKB/TrEMBL
  FAD/NAD-bd_sf UniProtKB/TrEMBL
  RNLS UniProtKB/TrEMBL
KEGG Report hgl:101715856 UniProtKB/TrEMBL
NCBI Gene Rnls ENTREZGENE
PANTHER PTHR23357 UniProtKB/TrEMBL
  RENALASE UniProtKB/TrEMBL
Pfam Amino_oxidase UniProtKB/TrEMBL
  NAD_binding_8 UniProtKB/TrEMBL
Superfamily-SCOP SSF51905 UniProtKB/TrEMBL
UniProt A0A0N8ETP8 ENTREZGENE, UniProtKB/TrEMBL