NTPCR (nucleoside-triphosphatase, cancer-related)

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Gene: NTPCR (nucleoside-triphosphatase, cancer-related) Chlorocebus sabaeus

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Symbol:

NTPCR

Name:

nucleoside-triphosphatase, cancer-related

RGD ID:

18780286

Description:

ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ribonucleoside triphosphate phosphatase activity (inferred); PARTICIPATES IN thiamine metabolic pathway; ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); parathyroid carcinoma (ortholog); FOUND IN mitochondrion (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

cancer-related nucleoside-triphosphatase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	70,162,533 - 70,190,936 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	70,162,571 - 70,190,517 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	72,116,323 - 72,149,590 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

gastrointestinal stromal tumor (ISO)

parathyroid carcinoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

mitochondrion (ISO)

Molecular Function

ATP binding (IEA)

ATP hydrolysis activity (IEA)

ribonucleoside triphosphate phosphatase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

thiamine metabolic pathway (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

NTPCR
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	70,162,533 - 70,190,936 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	70,162,571 - 70,190,517 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	72,116,323 - 72,149,590 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

NTPCR
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	232,950,611 - 232,983,882 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	232,950,605 - 232,983,882 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	233,086,357 - 233,119,628 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	231,152,993 - 231,180,842 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	206,356,751 - 206,384,600 (+)	NCBI		Celera
Cytogenetic Map	1	q42.2	NCBI
HuRef	1	203,576,326 - 203,604,129 (+)	NCBI		HuRef
CHM1_1	1	234,359,916 - 234,387,769 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	232,336,950 - 232,370,221 (+)	NCBI		T2T-CHM13v2.0

Ntpcr
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	126,456,724 - 126,474,974 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	126,456,702 - 126,474,974 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	125,729,975 - 125,748,235 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	125,729,963 - 125,748,235 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	128,258,103 - 128,272,135 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	128,620,319 - 128,634,300 (+)	NCBI		MGSCv36	mm8
Celera	8	130,047,167 - 130,061,146 (+)	NCBI		Celera
Cytogenetic Map	8	E2	NCBI
cM Map	8	73.65	NCBI

Ntpcr
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	70,598,816 - 70,612,580 (+)	NCBI		GRCr8
mRatBN7.2	19	53,701,496 - 53,715,260 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	53,695,976 - 53,715,202 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	60,492,517 - 60,506,338 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	61,350,872 - 61,364,561 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	63,426,814 - 63,440,504 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	58,565,576 - 58,579,276 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	58,565,576 - 58,579,265 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	69,262,818 - 69,276,518 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	55,939,045 - 55,952,745 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	55,935,403 - 55,957,241 (+)	NCBI
Celera	19	53,062,575 - 53,076,275 (+)	NCBI		Celera
Cytogenetic Map	19	q12	NCBI

Ntpcr
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955492	6,253,087 - 6,279,016 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955492	6,253,087 - 6,279,016 (-)	NCBI	ChiLan1.0	ChiLan1.0

NTPCR
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	16,228,786 - 16,256,987 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	16,435,012 - 16,463,205 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	208,488,080 - 208,521,291 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	213,514,986 - 213,543,680 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	213,514,986 - 213,543,680 (+)	Ensembl	panpan1.1		panPan2

NTPCR
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	6,704,571 - 6,733,820 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	6,693,240 - 6,722,006 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	6,726,875 - 6,755,692 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	6,725,334 - 6,756,323 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	6,736,907 - 6,765,707 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	6,857,165 - 6,885,962 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	7,081,335 - 7,110,107 (-)	NCBI		UU_Cfam_GSD_1.0

Ntpcr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	42,392,764 - 42,407,048 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936484	18,557,958 - 18,571,254 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936484	18,557,999 - 18,571,236 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NTPCR
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	57,802,565 - 57,833,151 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	57,802,564 - 57,833,155 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

Ntpcr
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624775	17,006,662 - 17,033,740 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624775	16,996,658 - 17,033,745 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007989810	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007989811	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000023	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000008288 ⟹ ENSCSAP00000006437

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	25	70,162,571 - 70,190,517 (+)	Ensembl

RefSeq Acc Id:

XM_007989810 ⟹ XP_007988001

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	25	70,162,533 - 70,190,936 (+)	NCBI
Vero_WHO_p1.0	NW_023666055	72,116,323 - 72,149,590 (+)	NCBI

Sequence:

show sequence

CCGCTTGGGGGCGTGGCCTGCGACACGCGGTGGGCGGGTCCTGACTCGCGACCCTAGTCCGGAC
CTGAGCTGAATAGCGACCCCAACCCGGACTGCTACCCTGACCGCAACCCCTACCCCCGCCCACC
CGCATGGCCCGGCACGTGTTCCTAACGGGGCCCCCAGGGGTTGGAAAAACAACATTGATCCAGA
AAGCCAGTGAGGTTTTAAAATCATCTGGTGTGCCTGTCGATGGATTTTATACAGAAGAAGTCAG
ACAGGGAGGGAGAAGAATAGGATTCGATGTCGTCACGCTGTCCGGCACCCGGGGGCCTTTATCG
AGAGTTGGGTTAGAGCCTCCACCTGGAAAACGTGAATGCCGAGTTGGGCAGTATGTGGTTGACA
TGACATCTTTTGAGCAGTTGGCACTCCCCGTCTTGAGGAATGCCGACTGCAGCAGTGGTCCAGG
GCAAAGAGTGTGTGTCATCGATGAGATTGGGAAGATGGAGCTCTTCAGTCAGCCTTTCATTCAA
GCTGTGCGTCAGACGCTGTCTACCCCAGGGACTATAATCCTTGGCACAATCCCAGTTCCTAAAG
GAAAGCCACTGGCTCTTGTAGAAGAAATCCGAAACAGAAAGGATGTGAAGGTGTTTAATGTCAC
CAAGGAAAACAGAAACCACCTTCTGCCAGATATCGTGACGTGTGTGCAGAGCAGCAGGAAGTGA
AGACACGTGCGTTCCTGCCTCCCTTGAAGGAGTGCCCAGTTCAAGAGGAGCCCAATGGAGCCCT
CCTGTCGAGGCTGTATGCCTATGGGGTTATGGAACCTTGTGGGCTTTTCTAGAGAAAACTCAAC
AGCTGTTTTCCATAAAGTGTTTAAAAGATTAAATTAGCCTTAATGCTGGATTGTCTGTACAAGA
TGAACAATCCATTGTGGCTTATTTATGCTTAAAGATTTCTTGTTTATTTCCTCTTGCAGTCATG
CACATGATTTGGGTAAATTATGAGATGAGAAATGGTTTTCAGAGTATTAGATGGAATTCGCCCC
TGTTGAAGTTTATAAATGTGTTCAGGGGAAGGGGGAGGAAAGAGTTCACTGCCTAATCAGTTTT
GCATGTCATGAAAATTAAATTCCTCTCCAGGTGTA

hide sequence

RefSeq Acc Id:

XM_007989811 ⟹ XP_007988002

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	25	70,166,482 - 70,190,936 (+)	NCBI
Vero_WHO_p1.0	NW_023666055	72,120,311 - 72,149,590 (+)	NCBI

Sequence:

show sequence

ATATTGGGAGCAAGACTCATATTTTAAAAAGTCATGGTGACAGGTGAAGGCCCATGTTGAAAGG
GGTTGGAAAAACAACATTGATCCAGAAAGCCAGTGAGGTTTTAAAATCATCTGGTGTGCCTGTC
GATGGATTTTATACAGAAGAAGTCAGACAGGGAGGGAGAAGAATAGGATTCGATGTCGTCACGC
TGTCCGGCACCCGGGGGCCTTTATCGAGAGTTGGGTTAGAGCCTCCACCTGGAAAACGTGAATG
CCGAGTTGGGCAGTATGTGGTTGACATGACATCTTTTGAGCAGTTGGCACTCCCCGTCTTGAGG
AATGCCGACTGCAGCAGTGGTCCAGGGCAAAGAGTGTGTGTCATCGATGAGATTGGGAAGATGG
AGCTCTTCAGTCAGCCTTTCATTCAAGCTGTGCGTCAGACGCTGTCTACCCCAGGGACTATAAT
CCTTGGCACAATCCCAGTTCCTAAAGGAAAGCCACTGGCTCTTGTAGAAGAAATCCGAAACAGA
AAGGATGTGAAGGTGTTTAATGTCACCAAGGAAAACAGAAACCACCTTCTGCCAGATATCGTGA
CGTGTGTGCAGAGCAGCAGGAAGTGAAGACACGTGCGTTCCTGCCTCCCTTGAAGGAGTGCCCA
GTTCAAGAGGAGCCCAATGGAGCCCTCCTGTCGAGGCTGTATGCCTATGGGGTTATGGAACCTT
GTGGGCTTTTCTAGAGAAAACTCAACAGCTGTTTTCCATAAAGTGTTTAAAAGATTAAATTAGC
CTTAATGCTGGATTGTCTGTACAAGATGAACAATCCATTGTGGCTTATTTATGCTTAAAGATTT
CTTGTTTATTTCCTCTTGCAGTCATGCACATGATTTGGGTAAATTATGAGATGAGAAATGGTTT
TCAGAGTATTAGATGGAATTCGCCCCTGTTGAAGTTTATAAATGTGTTCAGGGGAAGGGGGAGG
AAAGAGTTCACTGCCTAATCAGTTTTGCATGTCATGAAAATTAAATTCCTCTCCAGGTGTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_007988001	(Get FASTA)	NCBI Sequence Viewer
	XP_007988002	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000006437
	ENSCSAP00000006437.1

RefSeq Acc Id:	XP_007988001 ⟸ XM_007989810
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9RCU8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_007988002 ⟸ XM_007989811
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSCSAP00000006437 ⟸ ENSCSAT00000008288

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000010197	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000008288.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	AAA+_ATPase	UniProtKB/TrEMBL
	Nuc-triphosphatase_THEP1	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
KEGG Report	csab:103230767	UniProtKB/TrEMBL
NCBI Gene	NTPCR	ENTREZGENE
PANTHER	CANCER-RELATED NUCLEOSIDE-TRIPHOSPHATASE	UniProtKB/TrEMBL
	PTHR43146	UniProtKB/TrEMBL
Pfam	NTPase_1	UniProtKB/TrEMBL
SMART	AAA	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A0D9RCU8	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Annotations - SMPDB