MMP20 (matrix metallopeptidase 20) - Rat Genome Database

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Pathways
Gene: MMP20 (matrix metallopeptidase 20) Chlorocebus sabaeus
Analyze
Symbol: MMP20
Name: matrix metallopeptidase 20
RGD ID: 18774249
Description: ENCODES a protein that exhibits endopeptidase activity (inferred); metalloendopeptidase activity (inferred); metallopeptidase activity (inferred); INVOLVED IN amelogenesis (ortholog); extracellular matrix disassembly (ortholog); protein catabolic process (ortholog); ASSOCIATED WITH amelogenesis imperfecta (ortholog); amelogenesis imperfecta hypomaturation type 2A2 (ortholog); autistic disorder (ortholog); FOUND IN extracellular matrix (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: matrix metalloproteinase-20
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap1199,087,481 - 99,135,985 (-)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366604331,863,724 - 31,912,227 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.1193,946,136 - 93,997,656 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl193,947,582 - 93,996,815 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MMP20
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap1199,087,481 - 99,135,985 (-)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366604331,863,724 - 31,912,227 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.1193,946,136 - 93,997,656 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl193,947,582 - 93,996,815 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
MMP20
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811102,576,832 - 102,625,332 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11102,576,832 - 102,625,332 (-)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh3711102,447,563 - 102,496,063 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611101,952,776 - 102,001,273 (-)NCBIBuild 36Build 36hg18NCBI36
Build 3411101,952,775 - 102,001,273NCBI
Celera1199,609,116 - 99,657,267 (-)NCBICelera
Cytogenetic Map11q22.2NCBI
HuRef1198,374,581 - 98,423,040 (-)NCBIHuRef
CHM1_111102,330,639 - 102,378,769 (-)NCBICHM1_1
T2T-CHM13v2.011102,579,028 - 102,627,492 (-)NCBIT2T-CHM13v2.0
Mmp20
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3997,628,232 - 7,674,969 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl97,628,232 - 7,674,980 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3897,628,231 - 7,674,968 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl97,628,231 - 7,674,979 (+)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv3797,628,231 - 7,674,968 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3697,628,240 - 7,674,979 (+)NCBIMGSCv36mm8
Celera95,018,752 - 5,065,648 (+)NCBICelera
Cytogenetic Map9A1NCBI
cM Map92.46NCBI
Mmp20
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8813,074,279 - 13,114,894 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl813,074,279 - 13,114,894 (+)EnsemblGRCr8
mRatBN7.284,789,415 - 4,830,035 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl84,789,415 - 4,830,035 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx88,748,991 - 8,789,552 (+)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.087,046,772 - 7,087,333 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.085,049,092 - 5,089,708 (+)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd813,050,566 - 13,091,178 (+)NCBI
Lyon_Normotensive815,252,781 - 15,293,395 (+)NCBI
Lyon_Hypertensive813,860,333 - 13,900,891 (+)NCBI
F344_StmMcwi85,179,500 - 5,220,063 (+)NCBI
Rnor_6.085,823,147 - 5,875,555 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl85,833,359 - 5,875,232 (+)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.085,826,487 - 5,877,399 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.484,467,263 - 4,507,865 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera86,348,869 - 6,389,463 (+)NCBICelera
RGSC_v3.184,467,232 - 4,507,654 (+)NCBI
Cytogenetic Map8q11NCBI
Mmp20
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554125,815,450 - 5,869,016 (-)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_0049554125,815,450 - 5,869,016 (-)NCBIChiLan1.0ChiLan1.0
MMP20
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29103,369,818 - 103,419,591 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111104,459,433 - 104,507,921 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01197,518,573 - 97,566,881 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111101,011,084 - 101,059,322 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11101,011,084 - 101,059,322 (-)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
MMP20
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1529,106,717 - 29,154,628 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl529,106,717 - 29,155,071 (+)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha529,054,854 - 29,102,065 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0529,158,125 - 29,205,612 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl529,158,125 - 29,205,612 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1529,193,037 - 29,240,434 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0529,072,357 - 29,119,832 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0529,247,616 - 29,295,291 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mmp20
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap1487,447,596 - 87,492,076 (-)NCBImIctTri1.hap1
HiC_Itri_2NW_02440494786,183,414 - 86,226,115 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365515,310,426 - 5,352,883 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365515,310,426 - 5,352,883 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MMP20
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl933,261,443 - 33,308,047 (-)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.1933,261,448 - 33,308,047 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2937,208,054 - 37,254,669 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Mmp20
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624878277,569 - 320,093 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_004624878277,558 - 320,093 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl568,162,718 - 68,205,178 (-)Ensembl
Mmp20
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v183,848,404 - 3,886,221 (+)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1

Variants

.
Variants in MMP20
1073 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
54 15 20 32 32 42 3

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008020664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JBLKOC010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000001247   ⟹   ENSCSAP00000014830
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl193,947,582 - 93,996,815 (-)Ensembl
RefSeq Acc Id: XM_008020664   ⟹   XP_008018855
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
mChlSab1.0.hap1199,087,481 - 99,135,985 (-)NCBI
Vero_WHO_p1.0NW_02366604331,863,724 - 31,912,227 (+)NCBI
ChlSab1.1193,946,136 - 93,997,656 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008018855 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000014830
  ENSCSAP00000014830.1
RefSeq Acc Id: XP_008018855   ⟸   XM_008020664
- UniProtKB: A0A0D9S1U1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000014830   ⟸   ENSCSAT00000001247


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000003216 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000001247.1 UniProtKB/TrEMBL
Gene3D-CATH 2.110.10.10 UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/TrEMBL
InterPro Hemopexin-like_dom UniProtKB/TrEMBL
  Hemopexin-like_dom_sf UniProtKB/TrEMBL
  Hemopexin-like_repeat UniProtKB/TrEMBL
  M10A_MMP UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/TrEMBL
  Pept_M10_metallopeptidase UniProtKB/TrEMBL
  Pept_M10A UniProtKB/TrEMBL
  Pept_M10A_Zn_BS UniProtKB/TrEMBL
  Peptidase_Metallo UniProtKB/TrEMBL
  Peptidoglycan-bd-like UniProtKB/TrEMBL
  PGBD-like_sf UniProtKB/TrEMBL
KEGG Report csab:103248341 UniProtKB/TrEMBL
NCBI Gene MMP20 ENTREZGENE
PANTHER MATRIX METALLOPROTEINASE UniProtKB/TrEMBL
  PTHR10201:SF125 UniProtKB/TrEMBL
Pfam Hemopexin UniProtKB/TrEMBL
  Peptidase_M10 UniProtKB/TrEMBL
  PG_binding_1 UniProtKB/TrEMBL
PIRSF Peptidase_M10A_matrix UniProtKB/TrEMBL
PRINTS MATRIXIN UniProtKB/TrEMBL
PROSITE CYSTEINE_SWITCH UniProtKB/TrEMBL
  HEMOPEXIN_2 UniProtKB/TrEMBL
SMART SM00120 UniProtKB/TrEMBL
  ZnMc UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
  SSF47090 UniProtKB/TrEMBL
  SSF50923 UniProtKB/TrEMBL
UniProt A0A0D9S1U1 ENTREZGENE, UniProtKB/TrEMBL