TRMT2A (tRNA methyltransferase 2 homolog A) - Rat Genome Database

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Gene: TRMT2A (tRNA methyltransferase 2 homolog A) Chlorocebus sabaeus
Analyze
Symbol: TRMT2A
Name: tRNA methyltransferase 2 homolog A
RGD ID: 18771507
Description: ENCODES a protein that exhibits C-methyltransferase activity (inferred); methyltransferase activity (inferred); RNA binding (inferred); INVOLVED IN methylation (inferred); RNA processing (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); chromosome 22q11.2 deletion syndrome, distal (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tRNA (uracil-5-)-methyltransferase homolog A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1195,622,542 - 5,627,923 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl195,622,630 - 5,627,257 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660851,305,872 - 1,311,254 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
TRMT2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1195,622,542 - 5,627,923 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl195,622,630 - 5,627,257 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660851,305,872 - 1,311,254 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TRMT2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382220,111,875 - 20,117,226 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2220,111,875 - 20,117,392 (-)EnsemblGRCh38hg38GRCh38
GRCh372220,099,398 - 20,104,749 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362218,479,398 - 18,484,768 (-)NCBINCBI36Build 36hg18NCBI36
Celera223,951,448 - 3,956,818 (-)NCBICelera
Cytogenetic Map22q11.21ENTREZGENE
HuRef223,720,050 - 3,725,479 (-)NCBIHuRef
CHM1_12220,099,073 - 20,104,502 (-)NCBICHM1_1
T2T-CHM13v2.02220,490,925 - 20,496,276 (-)NCBIT2T-CHM13v2.0
Trmt2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391618,066,747 - 18,072,636 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1618,066,543 - 18,072,636 (+)EnsemblGRCm39 Ensembl
GRCm381618,248,847 - 18,254,772 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1618,248,679 - 18,254,772 (+)EnsemblGRCm38mm10GRCm38
MGSCv371618,248,976 - 18,253,595 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361618,162,242 - 18,167,065 (+)NCBIMGSCv36mm8
Celera1618,821,629 - 18,826,248 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.31NCBI
Trmt2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81196,241,998 - 96,246,719 (-)NCBIGRCr8
mRatBN7.21182,737,689 - 82,742,423 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,737,689 - 82,742,336 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1191,466,077 - 91,470,686 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01184,127,305 - 84,131,914 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01183,180,820 - 83,185,429 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01186,885,671 - 86,890,482 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1186,885,626 - 86,890,390 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01189,979,609 - 89,984,427 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41184,731,490 - 84,736,099 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11184,772,087 - 84,776,696 (-)NCBI
Celera1181,514,696 - 81,519,305 (-)NCBICelera
Cytogenetic Map11q23NCBI
Trmt2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544217,993,434 - 17,997,850 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544217,993,130 - 17,997,944 (+)NCBIChiLan1.0ChiLan1.0
TRMT2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22329,738,978 - 29,744,352 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12232,285,632 - 32,291,342 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0222,872,328 - 2,877,732 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12218,544,736 - 18,550,174 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2218,544,736 - 18,550,174 (-)Ensemblpanpan1.1panPan2
TRMT2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12629,219,549 - 29,224,155 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2629,219,812 - 29,226,233 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2629,178,491 - 29,183,068 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02630,623,618 - 30,628,196 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2630,623,786 - 30,630,273 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12628,671,464 - 28,676,060 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02628,296,828 - 28,301,424 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02629,381,756 - 29,386,414 (+)NCBIUU_Cfam_GSD_1.0
Trmt2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118138,734,886 - 138,739,581 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366194,014,508 - 4,020,569 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366194,015,072 - 4,020,163 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRMT2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1451,489,892 - 51,494,190 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11451,489,889 - 51,494,204 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21455,126,931 - 55,131,237 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Trmt2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624747722,607 - 727,947 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624747722,901 - 727,979 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000010092   ⟹   ENSCSAP00000008192
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl195,622,630 - 5,627,257 (+)Ensembl
RefSeq Acc Id: XM_007974998   ⟹   XP_007973189
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1195,622,542 - 5,627,923 (+)NCBI
Vero_WHO_p1.0NW_0236660851,305,872 - 1,311,254 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037994764   ⟹   XP_037850692
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660851,305,873 - 1,311,254 (-)NCBI
RefSeq Acc Id: XM_037994765   ⟹   XP_037850693
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660851,305,873 - 1,311,254 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007973189 (Get FASTA)   NCBI Sequence Viewer  
  XP_037850692 (Get FASTA)   NCBI Sequence Viewer  
  XP_037850693 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000008192
  ENSCSAP00000008192.1
RefSeq Acc Id: XP_007973189   ⟸   XM_007974998
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RHV3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000008192   ⟸   ENSCSAT00000010092
RefSeq Acc Id: XP_037850693   ⟸   XM_037994765
- Peptide Label: isoform X3
RefSeq Acc Id: XP_037850692   ⟸   XM_037994764
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000012001 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000010092.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.1070 UniProtKB/TrEMBL
  3.30.70.330 UniProtKB/TrEMBL
  3.40.50.150 UniProtKB/TrEMBL
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
  TRM2_euk UniProtKB/TrEMBL
  TRMT2A_RRM UniProtKB/TrEMBL
  U5_MeTrfase_fam UniProtKB/TrEMBL
KEGG Report csab:103222985 UniProtKB/TrEMBL
NCBI Gene TRMT2A ENTREZGENE
PANTHER PTHR45904 UniProtKB/TrEMBL
  TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG A UniProtKB/TrEMBL
Pfam tRNA_U5-meth_tr UniProtKB/TrEMBL
PROSITE RRM UniProtKB/TrEMBL
  SAM_MT_RNA_M5U UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
  SSF54928 UniProtKB/TrEMBL
UniProt A0A0D9RHV3 ENTREZGENE, UniProtKB/TrEMBL