ARL8B (ARF like GTPase 8B) - Rat Genome Database

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Gene: ARL8B (ARF like GTPase 8B) Chlorocebus sabaeus
Analyze
Symbol: ARL8B
Name: ARF like GTPase 8B (Ensembl:ADP ribosylation factor like GTPase 8B)
RGD ID: 18746925
Description: ENCODES a protein that exhibits alpha-tubulin binding (inferred); beta-tubulin binding (inferred); G protein activity (inferred); INVOLVED IN endosomal transport (ortholog); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN early endosome membrane (ortholog); lysosomal membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ADP ribosylation factor like GTPase 8B; ADP-ribosylation factor-like protein 8B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12241,192,458 - 41,247,048 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2241,192,484 - 41,244,822 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041125,375,218 - 125,430,540 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ARL8B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12241,192,458 - 41,247,048 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2241,192,484 - 41,244,822 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041125,375,218 - 125,430,540 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ARL8B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3835,122,292 - 5,180,911 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl35,122,249 - 5,180,911 (+)EnsemblGRCh38hg38GRCh38
GRCh3735,163,977 - 5,222,596 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3635,138,930 - 5,197,601 (+)NCBINCBI36Build 36hg18NCBI36
Build 3435,138,929 - 5,197,599NCBI
Celera35,101,851 - 5,160,484 (+)NCBICelera
Cytogenetic Map3p26.1NCBI
HuRef35,096,488 - 5,155,029 (+)NCBIHuRef
CHM1_135,114,266 - 5,172,980 (+)NCBICHM1_1
T2T-CHM13v2.035,116,223 - 5,174,843 (+)NCBIT2T-CHM13v2.0
Arl8b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396108,760,020 - 108,800,684 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6108,760,060 - 108,802,239 (+)EnsemblGRCm39 Ensembl
GRCm386108,783,059 - 108,823,723 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6108,783,099 - 108,825,278 (+)EnsemblGRCm38mm10GRCm38
MGSCv376108,733,053 - 108,773,717 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366108,748,887 - 108,789,496 (+)NCBIMGSCv36mm8
Celera6110,581,538 - 110,625,807 (+)NCBICelera
Cytogenetic Map6E2NCBI
cM Map649.87NCBI
Arl8b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84143,304,597 - 143,348,580 (+)NCBIGRCr8
mRatBN7.24141,748,634 - 141,792,605 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4141,748,587 - 141,792,596 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4147,170,642 - 147,214,634 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04142,951,373 - 142,995,361 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04141,595,356 - 141,639,346 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04140,837,745 - 140,881,866 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4140,837,745 - 140,881,865 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04217,450,494 - 217,494,707 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44144,299,366 - 144,344,431 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4130,399,834 - 130,444,983 (+)NCBICelera
Cytogenetic Map4q41NCBI
Arl8b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554218,231,582 - 8,276,907 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554218,231,337 - 8,276,907 (-)NCBIChiLan1.0ChiLan1.0
ARL8B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v225,128,058 - 5,185,788 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan135,132,816 - 5,190,365 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v035,069,592 - 5,127,301 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.135,169,950 - 5,225,550 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl35,169,950 - 5,225,543 (+)Ensemblpanpan1.1panPan2
ARL8B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12012,479,680 - 12,525,330 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2012,481,860 - 12,525,499 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2012,454,038 - 12,499,863 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02012,523,061 - 12,568,915 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2012,523,082 - 12,568,816 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12012,228,473 - 12,274,183 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02012,569,937 - 12,615,505 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02012,556,036 - 12,601,620 (-)NCBIUU_Cfam_GSD_1.0
Arl8b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494211,475,542 - 11,519,807 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365774,430,898 - 4,475,212 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365774,430,939 - 4,475,186 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARL8B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1361,640,671 - 61,698,374 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11361,640,619 - 61,696,819 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21367,874,603 - 67,921,540 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.21368,038,504 - 68,047,742 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Arl8b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477315,785,339 - 15,832,668 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477315,785,883 - 15,833,832 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007985075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000008978   ⟹   ENSCSAP00000007109
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2241,192,484 - 41,244,822 (+)Ensembl
RefSeq Acc Id: XM_007985075   ⟹   XP_007983266
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12241,192,458 - 41,247,048 (+)NCBI
Vero_WHO_p1.0NW_023666041125,375,218 - 125,430,540 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007983266 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000007109.1
RefSeq Acc Id: XP_007983266   ⟸   XM_007985075
- UniProtKB: A0A0D9RES0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000007109   ⟸   ENSCSAT00000008978


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000010899 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000008978.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro Arl8a/8b UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase_ARF/SAR UniProtKB/TrEMBL
NCBI Gene ARL8B ENTREZGENE
PANTHER ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8 UniProtKB/TrEMBL
  ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8B UniProtKB/TrEMBL
Pfam Arf UniProtKB/TrEMBL
PRINTS SAR1GTPBP UniProtKB/TrEMBL
PROSITE ARF UniProtKB/TrEMBL
  RAB UniProtKB/TrEMBL
SMART ARF UniProtKB/TrEMBL
  RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  SAR UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0D9RES0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-09-25 ARL8B  ARF like GTPase 8B  ARL8B  ADP ribosylation factor like GTPase 8B  Symbol and/or name change 5135510 APPROVED