UCMA (upper zone of growth plate and cartilage matrix associated) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: UCMA (upper zone of growth plate and cartilage matrix associated) Chlorocebus sabaeus
Analyze
Symbol: UCMA
Name: upper zone of growth plate and cartilage matrix associated
RGD ID: 18715872
Description: ENCODES a protein that exhibits BMP binding (inferred); INVOLVED IN negative regulation of osteoblast differentiation (ortholog); osteoblast differentiation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); hypoparathyroidism-deafness-renal disease syndrome (ortholog); FOUND IN cytoplasm (inferred); extracellular matrix (inferred); extracellular region (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: unique cartilage matrix-associated protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1913,262,924 - 13,276,091 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl913,263,264 - 13,275,328 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605118,791,584 - 18,805,491 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
UCMA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1913,262,924 - 13,276,091 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl913,263,264 - 13,275,328 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605118,791,584 - 18,805,491 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
UCMA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381013,221,766 - 13,234,374 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1013,221,766 - 13,234,374 (-)EnsemblGRCh38hg38GRCh38
GRCh371013,263,766 - 13,276,374 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361013,303,773 - 13,316,337 (-)NCBINCBI36Build 36hg18NCBI36
Build 341013,303,776 - 13,316,334NCBI
Celera1013,190,573 - 13,203,144 (-)NCBICelera
Cytogenetic Map10p13NCBI
HuRef1013,176,375 - 13,188,935 (-)NCBIHuRef
CHM1_11013,262,072 - 13,274,644 (-)NCBICHM1_1
T2T-CHM13v2.01013,234,493 - 13,247,115 (-)NCBIT2T-CHM13v2.0
Ucma
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3924,980,933 - 4,990,559 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl24,980,933 - 4,990,559 (+)EnsemblGRCm39 Ensembl
GRCm3824,976,122 - 4,985,748 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl24,976,122 - 4,985,748 (+)EnsemblGRCm38mm10GRCm38
MGSCv3724,897,168 - 4,906,794 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3624,893,453 - 4,903,017 (+)NCBIMGSCv36mm8
Celera24,931,464 - 4,941,091 (+)NCBICelera
Cytogenetic Map2A1NCBI
cM Map23.11NCBI
Ucma
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81778,203,268 - 78,212,996 (-)NCBIGRCr8
mRatBN7.21773,293,977 - 73,303,709 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1773,293,978 - 73,303,611 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1776,799,629 - 76,809,187 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01780,624,472 - 80,634,033 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01774,674,937 - 74,684,661 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01777,252,099 - 77,262,301 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1777,252,100 - 77,261,731 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01778,918,188 - 78,928,385 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41784,382,363 - 84,391,442 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11784,392,858 - 84,402,835 (-)NCBI
Celera1772,735,095 - 72,743,900 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
Ucma
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554621,195,608 - 1,204,266 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554621,195,738 - 1,204,255 (-)NCBIChiLan1.0ChiLan1.0
UCMA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2825,744,370 - 25,760,606 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11025,749,698 - 25,765,845 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01013,223,897 - 13,237,230 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11013,196,867 - 13,209,494 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1013,196,867 - 13,209,494 (-)Ensemblpanpan1.1panPan2
UCMA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1223,287,410 - 23,307,116 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl223,287,551 - 23,298,035 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha220,297,501 - 20,332,302 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0223,655,405 - 23,675,094 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl223,655,542 - 23,666,026 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1220,783,643 - 20,818,443 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0221,626,373 - 21,661,159 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0222,342,820 - 22,377,626 (+)NCBIUU_Cfam_GSD_1.0
LOC101955357
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093442,803,945 - 2,812,485 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936862404,476 - 413,561 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936862405,205 - 413,920 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UCMA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1048,460,688 - 48,471,286 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11048,460,713 - 48,471,213 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Ucma
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248055,775,019 - 5,781,957 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248055,775,019 - 5,781,957 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 6 6
Low 28 12 25
Below cutoff 2 6 16

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000011258   ⟹   ENSCSAP00000009337
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl913,263,264 - 13,275,328 (-)Ensembl
RefSeq Acc Id: XM_008002287   ⟹   XP_008000478
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1913,262,924 - 13,276,091 (-)NCBI
Vero_WHO_p1.0NW_02366605118,791,584 - 18,805,486 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037983338   ⟹   XP_037839266
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605118,791,584 - 18,805,491 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008000478 (Get FASTA)   NCBI Sequence Viewer  
  XP_037839266 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000009337.1
Reference Protein Sequences
RefSeq Acc Id: XP_008000478   ⟸   XM_008002287
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RL48 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000009337   ⟸   ENSCSAT00000011258
RefSeq Acc Id: XP_037839266   ⟸   XM_037983338
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000013163 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000011258.1 UniProtKB/TrEMBL
InterPro UCMA UniProtKB/TrEMBL
NCBI Gene UCMA ENTREZGENE
PANTHER PTHR28647 UniProtKB/TrEMBL
  UNIQUE CARTILAGE MATRIX-ASSOCIATED PROTEIN UniProtKB/TrEMBL
Pfam UCMA UniProtKB/TrEMBL
UniProt A0A0D9RL48 ENTREZGENE, UniProtKB/TrEMBL