LOC103234400 (EF-hand calcium-binding domain-containing protein 4A) - Rat Genome Database

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Gene: LOC103234400 (EF-hand calcium-binding domain-containing protein 4A) Chlorocebus sabaeus
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Symbol: LOC103234400 (Ensembl: CRACR2B)
Name: EF-hand calcium-binding domain-containing protein 4A (Ensembl:calcium release activated channel regulator 2B)
RGD ID: 18709108
Description: ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN store-operated calcium entry (inferred); ASSOCIATED WITH Beckwith-Wiedemann syndrome (ortholog); delta beta-thalassemia (ortholog); developmental and epileptic encephalopathy (ortholog); FOUND IN trans-Golgi network membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: calcium release activated channel regulator 2B; CRACR2B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11633,694 - 638,403 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1634,990 - 637,702 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603897,722,993 - 97,728,262 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
LOC103234400
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11633,694 - 638,403 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1634,990 - 637,702 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603897,722,993 - 97,728,262 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CRACR2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811826,157 - 831,991 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11826,144 - 831,991 (+)EnsemblGRCh38hg38GRCh38
GRCh3711827,919 - 831,991 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611817,585 - 821,991 (+)NCBINCBI36Build 36hg18NCBI36
Celera11894,861 - 898,627 (+)NCBICelera
Cytogenetic Map11p15.5NCBI
HuRef11642,852 - 647,258 (+)NCBIHuRef
CHM1_111826,546 - 830,952 (+)NCBICHM1_1
T2T-CHM13v2.011877,475 - 883,426 (+)NCBIT2T-CHM13v2.0
Cracr2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397141,041,007 - 141,046,526 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7141,041,007 - 141,046,526 (+)EnsemblGRCm39 Ensembl
GRCm387141,460,875 - 141,466,613 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7141,461,094 - 141,466,613 (+)EnsemblGRCm38mm10GRCm38
MGSCv377148,646,993 - 148,652,501 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367141,312,463 - 141,317,933 (+)NCBIMGSCv36mm8
Celera7141,254,886 - 141,260,393 (+)NCBICelera
Cytogenetic Map7F5NCBI
cM Map786.82NCBI
Cracr2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81205,987,957 - 205,993,515 (+)NCBIGRCr8
mRatBN7.21196,558,407 - 196,563,961 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1196,558,588 - 196,563,771 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1204,903,937 - 204,909,308 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01212,032,459 - 212,037,821 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01204,706,597 - 204,711,971 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01214,439,810 - 214,445,876 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,005,791 - 214,008,973 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,440,503 - 214,445,874 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01220,920,617 - 220,926,199 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41201,647,804 - 201,653,175 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1194,192,084 - 194,197,455 (+)NCBICelera
Cytogenetic Map1q41NCBI
Cracr2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547611,299,614 - 11,303,657 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547611,299,353 - 11,304,105 (-)NCBIChiLan1.0ChiLan1.0
CRACR2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v293,226,151 - 3,230,958 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1112,436,096 - 2,440,903 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011845,996 - 850,814 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111888,857 - 894,053 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11889,575 - 894,053 (+)Ensemblpanpan1.1panPan2
CRACR2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11845,188,527 - 45,194,077 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1845,190,250 - 45,194,038 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1843,855,476 - 43,861,081 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01845,853,437 - 45,859,041 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1845,855,553 - 45,859,002 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11845,319,036 - 45,323,792 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01844,883,025 - 44,888,623 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01845,621,151 - 45,626,754 (+)NCBIUU_Cfam_GSD_1.0
Cracr2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947586,435 - 592,273 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936888588,974 - 592,027 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936888586,126 - 592,275 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRACR2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2518,544 - 524,081 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12518,102 - 524,085 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22150,256 - 155,848 (-)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in LOC103234400
59 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000008624   ⟹   ENSCSAP00000006764
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1634,990 - 637,702 (+)Ensembl
RefSeq Acc Id: XM_007996127   ⟹   XP_007994318
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11633,694 - 638,403 (+)NCBI
Vero_WHO_p1.0NW_02366603897,723,600 - 97,728,257 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007996206   ⟹   XP_007994397
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11633,694 - 638,403 (+)NCBI
Vero_WHO_p1.0NW_02366603897,723,605 - 97,728,257 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007996280   ⟹   XP_007994471
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11633,694 - 638,067 (+)NCBI
Vero_WHO_p1.0NW_02366603897,723,572 - 97,727,831 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037998773   ⟹   XP_037854701
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603897,722,993 - 97,728,262 (+)NCBI
RefSeq Acc Id: XM_037998774   ⟹   XP_037854702
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603897,723,572 - 97,728,262 (+)NCBI
RefSeq Acc Id: XM_037998775   ⟹   XP_037854703
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603897,723,572 - 97,728,262 (+)NCBI
RefSeq Acc Id: XP_007994318   ⟸   XM_007996127
- Peptide Label: isoform X3
RefSeq Acc Id: XP_007994397   ⟸   XM_007996206
- Peptide Label: isoform X4
RefSeq Acc Id: XP_007994471   ⟸   XM_007996280
- Peptide Label: isoform X5
- UniProtKB: A0A0D9RDS5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000006764   ⟸   ENSCSAT00000008624
RefSeq Acc Id: XP_037854701   ⟸   XM_037998773
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037854703   ⟸   XM_037998775
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037854702   ⟸   XM_037998774
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000010538 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000008624.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro Ca-binding_regulatory UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
NCBI Gene CRACR2B ENTREZGENE
PANTHER CALCIUM-BINDING PROTEIN 8 UniProtKB/TrEMBL
  CALCIUM-BINDING PROTEIN 8-RELATED UniProtKB/TrEMBL
PROSITE EF_HAND_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A0D9RDS5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 LOC103234400  EF-hand calcium-binding domain-containing protein 4A  CRACR2B  calcium release activated channel regulator 2B  Symbol and/or name change 5135510 APPROVED