KLF13 (KLF transcription factor 13) - Rat Genome Database

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Gene: KLF13 (KLF transcription factor 13) Chlorocebus sabaeus
Analyze
Symbol: KLF13
Name: KLF transcription factor 13
RGD ID: 18672943
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN negative regulation of cell population proliferation (inferred); negative regulation of erythrocyte differentiation (inferred); positive regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); chromosome 15q13.3 microdeletion syndrome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Krueppel-like factor 13; Kruppel like factor 13
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12651,308,233 - 51,359,433 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2651,313,743 - 51,359,340 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604889,467,068 - 89,518,243 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
KLF13Green Monkeyautism spectrum disorder  ISOKLF13 (Homo sapiens)8554872ClinVar Annotator: match by term: Autism spectrum disorderClinVarPMID:19050728 more ...
KLF13Green Monkeyautistic disorder  ISOKLF13 (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
KLF13Green Monkeychromosome 15q13.3 microdeletion syndrome  ISOKLF13 (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome 15q13.3 microdeletion syndromeClinVarPMID:31690835
KLF13Green Monkeycolorectal cancer  ISOKLF13 (Homo sapiens)8554872ClinVar Annotator: match by term: Familial colorectal cancerClinVarPMID:22561515 more ...
KLF13Green Monkeycongenital heart disease  ISOKLF13 (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital heart diseaseClinVar 
KLF13Green MonkeyNeurodevelopmental Disorders  ISOKLF13 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
KLF13Green Monkeyschizophrenia  ISOKLF13 (Homo sapiens)8554872ClinVar Annotator: match by term: SchizophreniaClinVarPMID:21681106 and PMID:30208311
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
KLF13Green Monkeyendometriosis  ISOKLF13 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:21063030
KLF13Green Monkeymyocardial infarction  ISOKLF13 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:29122578


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
KLF13Green Monkeynegative regulation of cell population proliferation involved_inIEAUniProtKB:Q9JJZ6 and ensembl:ENSMUSP00000067680150520179 EnsemblGO_REF:0000107
KLF13Green Monkeynegative regulation of erythrocyte differentiation involved_inIEAUniProtKB:Q9JJZ6 and ensembl:ENSMUSP00000067680150520179 EnsemblGO_REF:0000107
KLF13Green Monkeypositive regulation of transcription by RNA polymerase II acts_upstream_of_or_withinIEAUniProtKB:Q9JJZ6 and ensembl:ENSMUSP00000067680150520179 EnsemblGO_REF:0000107
KLF13Green Monkeyregulation of transcription by RNA polymerase II acts_upstream_of_or_withinIEAUniProtKB:Q9JJZ6 and ensembl:ENSMUSP00000067680150520179 EnsemblGO_REF:0000107
KLF13Green Monkeyregulation of transcription by RNA polymerase II involved_inIEAPANTHER:PTN002354795150520179 TreeGrafterGO_REF:0000118

Molecular Function
1 to 10 of 10 rows

  
1 to 10 of 10 rows

PMID:30032202  



KLF13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12651,308,233 - 51,359,433 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2651,313,743 - 51,359,340 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604889,467,068 - 89,518,243 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
KLF13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381531,326,835 - 31,435,665 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1531,326,835 - 31,435,665 (+)EnsemblGRCh38hg38GRCh38
GRCh371531,619,038 - 31,727,868 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361529,406,375 - 29,457,394 (+)NCBINCBI36Build 36hg18NCBI36
Build 341529,406,374 - 29,457,393NCBI
Celera159,344,613 - 9,395,650 (+)NCBICelera
Cytogenetic Map15q13.3NCBI
HuRef158,795,864 - 8,846,859 (+)NCBIHuRef
CHM1_11531,609,998 - 31,661,037 (+)NCBICHM1_1
T2T-CHM13v2.01529,120,947 - 29,230,012 (+)NCBIT2T-CHM13v2.0
Klf13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39763,536,099 - 63,588,663 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl763,536,099 - 63,588,663 (-)EnsemblGRCm39 Ensembl
GRCm38763,886,351 - 63,938,915 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl763,886,351 - 63,938,915 (-)EnsemblGRCm38mm10GRCm38
MGSCv37771,031,237 - 71,083,801 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36763,770,317 - 63,817,807 (-)NCBIMGSCv36mm8
Celera761,323,891 - 61,376,961 (-)NCBICelera
Cytogenetic Map7CNCBI
cM Map734.58NCBI
Klf13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81126,917,671 - 126,948,436 (-)NCBIGRCr8
mRatBN7.21117,505,857 - 117,536,626 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1117,503,602 - 117,551,227 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1125,481,839 - 125,512,610 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01132,664,376 - 132,695,144 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01125,495,077 - 125,525,856 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01124,772,596 - 124,803,363 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1124,772,596 - 124,803,363 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01125,883,341 - 125,914,101 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41118,368,164 - 118,398,938 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1109,762,642 - 109,793,430 (-)NCBICelera
Cytogenetic Map1q22NCBI
Klf13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541630,087,705 - 30,137,437 (+)NCBIChiLan1.0ChiLan1.0
KLF13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21620,134,237 - 20,281,052 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11524,858,345 - 25,004,850 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0159,818,294 - 9,964,912 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11528,895,493 - 28,907,236 (+)NCBIpanpan1.1PanPan1.1panPan2
KLF13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha340,305,981 - 40,356,168 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0338,007,383 - 38,057,914 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl338,012,977 - 38,057,834 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1337,539,905 - 37,590,337 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0337,793,598 - 37,843,701 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0338,003,294 - 38,053,725 (-)NCBIUU_Cfam_GSD_1.0
Klf13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640145,759,345 - 145,807,029 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936483532,736 - 575,237 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936483477,490 - 575,143 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLF13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1143,493,527 - 143,540,563 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11143,499,136 - 143,540,233 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21159,400,720 - 159,485,260 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Klf13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247681,573,326 - 1,612,211 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247681,568,168 - 1,612,324 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in KLF13
1342 total Variants



ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20


RefSeq Transcripts XM_008017194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000004902   ⟹   ENSCSAP00000003143
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2651,313,743 - 51,359,340 (-)Ensembl
RefSeq Acc Id: XM_008017194   ⟹   XP_008015385
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12651,308,233 - 51,359,433 (-)NCBI
Vero_WHO_p1.0NW_02366604889,467,068 - 89,518,243 (+)NCBI
Sequence:
Protein RefSeqs XP_008015385 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000003143
  ENSCSAP00000003143.1
RefSeq Acc Id: XP_008015385   ⟸   XM_008017194
- UniProtKB: A0A0D9R3F4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000003143   ⟸   ENSCSAT00000004902



1 to 15 of 15 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCSAG00000006853 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000004902.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
KEGG Report csab:103245940 UniProtKB/TrEMBL
NCBI Gene KLF13 ENTREZGENE
PANTHER KRUEPPEL-LIKE FACTOR 13 UniProtKB/TrEMBL
  KRUEPPEL-LIKE TRANSCRIPTION FACTOR UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A0D9R3F4 ENTREZGENE, UniProtKB/TrEMBL
1 to 15 of 15 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-07-12 KLF13  KLF transcription factor 13  KLF13  Kruppel like factor 13  Symbol and/or name change 5135510 APPROVED