SOX11 (SRY-box transcription factor 11) - Rat Genome Database

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Gene: SOX11 (SRY-box transcription factor 11) Chlorocebus sabaeus
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Symbol: SOX11
Name: SRY-box transcription factor 11
RGD ID: 18598913
Description: ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); INVOLVED IN kidney development (ortholog); oligodendrocyte development (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Coffin-Siris syndrome (ortholog); Coffin-Siris syndrome 9 (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SRY-box 11; transcription factor SOX-11
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114101,982,551 - 101,991,305 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl14101,989,895 - 101,991,220 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604510,348,860 - 10,357,867 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
brain development  (IEA)
camera-type eye morphogenesis  (IEA)
cell differentiation  (IEA)
closure of optic fissure  (IEA)
cornea development in camera-type eye  (IEA)
embryonic digestive tract morphogenesis  (IEA)
embryonic skeletal system morphogenesis  (IEA)
eyelid development in camera-type eye  (IEA)
glial cell development  (IEA)
glial cell proliferation  (IEA)
hard palate development  (IEA)
kidney development  (ISO)
lens morphogenesis in camera-type eye  (IEA)
lung morphogenesis  (IEA)
negative regulation of gene expression  (IEA)
negative regulation of glial cell proliferation  (IEA)
negative regulation of lymphocyte proliferation  (IEA)
negative regulation of transcription by RNA polymerase II  (IEA)
nervous system development  (IEA)
neuroepithelial cell differentiation  (IEA)
neuron differentiation  (IEA)
noradrenergic neuron differentiation  (IEA)
oligodendrocyte development  (ISO)
outflow tract morphogenesis  (IEA)
positive regulation of BMP signaling pathway  (IEA)
positive regulation of DNA-templated transcription  (IEA)
positive regulation of gene expression  (IEA)
positive regulation of hippo signaling  (IEA)
positive regulation of hormone secretion  (IEA)
positive regulation of lens epithelial cell proliferation  (IEA)
positive regulation of neurogenesis  (IEA)
positive regulation of neuron differentiation  (IEA)
positive regulation of ossification  (IEA)
positive regulation of osteoblast differentiation  (IEA)
positive regulation of stem cell proliferation  (IEA)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
regulation of transforming growth factor beta receptor signaling pathway  (IEA)
skeletal muscle cell differentiation  (IEA,ISO)
soft palate development  (IEA)
spinal cord development  (IEA)
sympathetic nervous system development  (IEA)
ventricular septum morphogenesis  (IEA)

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SOX11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114101,982,551 - 101,991,305 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl14101,989,895 - 101,991,220 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604510,348,860 - 10,357,867 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SOX11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3825,692,384 - 5,701,385 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl25,692,384 - 5,701,385 (+)EnsemblGRCh38hg38GRCh38
GRCh3725,832,516 - 5,841,517 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3625,750,250 - 5,758,968 (+)NCBINCBI36Build 36hg18NCBI36
Build 3425,783,396 - 5,792,114NCBI
Celera25,748,512 - 5,756,851 (+)NCBICelera
Cytogenetic Map2p25.2NCBI
HuRef25,676,397 - 5,685,112 (+)NCBIHuRef
CHM1_125,762,093 - 5,770,810 (+)NCBICHM1_1
T2T-CHM13v2.025,713,811 - 5,722,812 (+)NCBIT2T-CHM13v2.0
Sox11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391227,384,267 - 27,392,717 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1227,384,263 - 27,392,573 (-)EnsemblGRCm39 Ensembl
GRCm381227,334,268 - 27,342,718 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1227,334,264 - 27,342,574 (-)EnsemblGRCm38mm10GRCm38
MGSCv371228,019,133 - 28,027,583 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361227,921,484 - 27,928,980 (-)NCBIMGSCv36mm8
Celera1228,811,290 - 28,819,758 (-)NCBICelera
Cytogenetic Map12A2NCBI
cM Map129.95NCBI
Sox11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8649,736,773 - 49,738,794 (-)NCBIGRCr8
mRatBN7.2644,008,333 - 44,010,354 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl644,008,340 - 44,010,354 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx644,315,859 - 44,317,880 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0644,630,739 - 44,632,760 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0644,063,910 - 44,065,931 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0646,629,967 - 46,631,988 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl646,629,974 - 46,631,983 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0655,343,067 - 55,345,088 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4645,141,366 - 45,143,387 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1645,144,498 - 45,146,513 (-)NCBI
Celera643,252,857 - 43,254,878 (-)NCBICelera
Cytogenetic Map6q16NCBI
Sox11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554872,679,145 - 2,680,521 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554872,678,961 - 2,680,869 (-)NCBIChiLan1.0ChiLan1.0
SOX11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212120,808,899 - 120,820,381 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A120,812,876 - 120,824,358 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A5,699,738 - 5,711,210 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A5,840,399 - 5,841,762 (+)NCBIpanpan1.1PanPan1.1panPan2
SOX11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha173,570,850 - 3,572,822 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0173,680,433 - 3,682,409 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl173,680,517 - 3,682,010 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1173,573,068 - 3,575,034 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0173,576,503 - 3,578,454 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0173,580,950 - 3,582,922 (+)NCBIUU_Cfam_GSD_1.0
Sox11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050589,632,081 - 9,635,331 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004937107203,120 - 207,185 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SOX11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3129,798,854 - 129,800,197 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13129,797,438 - 129,800,568 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23138,751,621 - 138,754,531 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sox11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248464,044,893 - 4,046,248 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248464,043,010 - 4,046,660 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
74 34 17 31 31 60 20

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007971584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000018162   ⟹   ENSCSAP00000017626
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl14101,989,895 - 101,991,220 (-)Ensembl
RefSeq Acc Id: XM_007971584   ⟹   XP_007969775
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.114101,982,551 - 101,991,305 (-)NCBI
Vero_WHO_p1.0NW_02366604510,348,860 - 10,357,867 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007969775 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000017626
  ENSCSAP00000017626.1
RefSeq Acc Id: XP_007969775   ⟸   XM_007971584
- UniProtKB: A0A0D9S9T7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000017626   ⟸   ENSCSAT00000018162


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000000373 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000018162.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.30.10 UniProtKB/TrEMBL
InterPro HMG_box_dom UniProtKB/TrEMBL
  HMG_box_dom_sf UniProtKB/TrEMBL
  SOX-11/4 UniProtKB/TrEMBL
  SRY-related_HMG-box_TFs UniProtKB/TrEMBL
KEGG Report csab:103220895 UniProtKB/TrEMBL
NCBI Gene SOX11 ENTREZGENE
PANTHER PTHR10270:SF113 UniProtKB/TrEMBL
  SOX TRANSCRIPTION FACTOR UniProtKB/TrEMBL
Pfam HMG_box UniProtKB/TrEMBL
PIRSF SOX-12/11/4a UniProtKB/TrEMBL
PROSITE HMG_BOX_2 UniProtKB/TrEMBL
SMART HMG UniProtKB/TrEMBL
Superfamily-SCOP SSF47095 UniProtKB/TrEMBL
UniProt A0A0D9S9T7 ENTREZGENE, UniProtKB/TrEMBL