LOC103235709 (transmembrane serine protease 11B) - Rat Genome Database

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Gene: LOC103235709 (transmembrane serine protease 11B) Chlorocebus sabaeus
Analyze
Symbol: LOC103235709 (Ensembl: TMPRSS11B)
Name: transmembrane serine protease 11B
RGD ID: 18551392
Description: ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH Breast Cancer, Familial (ortholog); FOUND IN extracellular region (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: TMPRSS11B; transmembrane protease serine 11B; transmembrane protease, serine 11B
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap171,133,244 - 1,151,751 (+)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_023666066819,735 - 838,550 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.17734,885 - 748,755 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7734,900 - 748,477 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
proteolysis  (IEA)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
LOC103235709
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap171,133,244 - 1,151,751 (+)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_023666066819,735 - 838,550 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.17734,885 - 748,755 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7734,900 - 748,477 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
TMPRSS11B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38468,226,653 - 68,245,694 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl468,226,653 - 68,245,694 (-)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh37469,092,371 - 69,111,412 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36468,774,966 - 68,794,004 (-)NCBIBuild 36Build 36hg18NCBI36
Celera466,551,717 - 66,570,749 (-)NCBICelera
Cytogenetic Map4q13.2NCBI
HuRef465,004,927 - 65,023,958 (-)NCBIHuRef
CHM1_1469,129,015 - 69,148,054 (-)NCBICHM1_1
T2T-CHM13v2.0471,666,935 - 71,685,995 (-)NCBIT2T-CHM13v2.0
Tmprss11b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39586,806,326 - 86,824,221 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl586,805,490 - 86,824,221 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38586,659,522 - 86,676,298 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl586,657,631 - 86,676,362 (-)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv37587,088,547 - 87,105,323 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36587,732,998 - 87,750,911 (-)NCBIMGSCv36mm8
Celera583,879,850 - 83,896,603 (-)NCBICelera
Cytogenetic Map5E1NCBI
cM Map543.56NCBI
Tmprss11b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81421,738,760 - 21,763,896 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1421,738,760 - 21,762,107 (+)EnsemblGRCr8
mRatBN7.21421,383,936 - 21,407,283 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1421,383,862 - 21,408,817 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1421,740,535 - 21,760,392 (+)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01423,059,465 - 23,079,322 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01421,590,547 - 21,610,408 (+)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1422,034,154 - 22,057,900 (+)NCBI
Lyon_Normotensive1422,139,247 - 22,162,993 (+)NCBI
Lyon_Hypertensive1422,147,125 - 22,170,871 (+)NCBI
F344_StmMcwi1422,124,155 - 22,147,893 (+)NCBI
Rnor_6.01424,103,768 - 24,125,260 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1424,103,954 - 24,123,253 (-)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.01423,940,743 - 23,960,116 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41423,009,055 - 23,029,587 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1420,876,772 - 20,895,405 (+)NCBICelera
RGSC_v3.11423,009,054 - 23,029,587 (+)NCBI
Cytogenetic Map14p21NCBI
TMPRSS11B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2361,648,353 - 61,670,960 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1461,858,476 - 61,881,030 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0455,802,811 - 55,825,366 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1462,200,252 - 62,219,386 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl462,200,414 - 62,218,523 (+)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
LOC482175
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11358,648,662 - 58,656,588 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1358,577,447 - 58,587,987 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01359,350,520 - 59,361,072 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.11358,998,034 - 59,010,354 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01358,481,818 - 58,495,882 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01359,501,056 - 59,513,565 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101971243
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap1950,872,363 - 50,887,347 (-)NCBImIctTri1.hap1
HiC_Itri_2NW_02440528517,751,893 - 17,770,648 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936582314,997 - 333,837 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936582315,088 - 333,814 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100513484
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl865,882,623 - 65,902,436 (-)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.1865,881,985 - 65,898,898 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2870,305,132 - 70,321,065 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Tmprss11b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v111279,966 - 293,486 (+)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1

Variants

.
Variants in LOC103235709
289 total Variants

Expression

RNA-SEQ Expression

ectoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
1 18 18 18 1

Sequence


Ensembl Acc Id: ENSCSAT00000003277   ⟹   ENSCSAP00000001558
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl7734,900 - 748,477 (+)Ensembl
RefSeq Acc Id: XM_037989389   ⟹   XP_037845317
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
mChlSab1.0.hap171,133,244 - 1,151,751 (+)NCBI
Vero_WHO_p1.0NW_023666066819,735 - 838,550 (+)NCBI
Protein Sequences
Protein RefSeqs XP_037845317 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000001558.1
Ensembl Acc Id: ENSCSAP00000001558   ⟸   ENSCSAT00000003277
RefSeq Acc Id: XP_037845317   ⟸   XM_037989389
- UniProtKB: A0A0D9QYW9 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000005243 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000003277.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
  3.30.70.960 UniProtKB/TrEMBL
InterPro Pept_S1A_HAT/DESC1 UniProtKB/TrEMBL
  Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  SEA_dom UniProtKB/TrEMBL
  SEA_dom_sf UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
NCBI Gene TMPRSS11B ENTREZGENE
PANTHER ACROSIN-RELATED UniProtKB/TrEMBL
  HYALIN UniProtKB/TrEMBL
Pfam SEA UniProtKB/TrEMBL
  Trypsin UniProtKB/TrEMBL
PIRSF TMPRSS11ABCDE UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE SEA UniProtKB/TrEMBL
  TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
SMART Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
  SSF82671 UniProtKB/TrEMBL
UniProt A0A0D9QYW9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 LOC103235709  transmembrane serine protease 11B  TMPRSS11B  transmembrane serine protease 11B  Symbol and/or name change 5135510 APPROVED