CENPC (centromere protein C) - Rat Genome Database

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Gene: CENPC (centromere protein C) Chlorocebus sabaeus
Analyze
Symbol: CENPC
Name: centromere protein C
RGD ID: 18544800
Description: ENCODES a protein that exhibits centromeric DNA binding (inferred); identical protein binding (inferred); INVOLVED IN attachment of mitotic spindle microtubules to kinetochore (inferred); chromosome segregation (inferred); kinetochore assembly (inferred); ASSOCIATED WITH CREST syndrome (ortholog); liver cirrhosis (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN condensed chromosome, centromeric region (inferred); inner kinetochore (inferred); kinetochore (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.171,393,336 - 1,464,189 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl71,393,348 - 1,467,989 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660661,480,301 - 1,552,594 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CENPC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.171,393,336 - 1,464,189 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl71,393,348 - 1,467,989 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660661,480,301 - 1,552,594 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CENPC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38467,468,762 - 67,545,503 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl467,468,762 - 67,545,503 (-)EnsemblGRCh38hg38GRCh38
GRCh37468,334,480 - 68,411,221 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36468,020,584 - 68,093,851 (-)NCBINCBI36Build 36hg18NCBI36
Build 34468,166,961 - 68,239,995NCBI
Celera465,800,619 - 65,873,659 (-)NCBICelera
Cytogenetic Map4q13.2NCBI
HuRef464,251,196 - 64,324,430 (-)NCBIHuRef
CHM1_1468,375,177 - 68,448,439 (-)NCBICHM1_1
T2T-CHM13v2.0470,911,881 - 70,988,601 (-)NCBIT2T-CHM13v2.0
Cenpc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39586,159,877 - 86,214,325 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl586,159,883 - 86,213,442 (-)EnsemblGRCm39 Ensembl
GRCm38586,012,018 - 86,065,962 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl586,012,024 - 86,065,583 (-)EnsemblGRCm38mm10GRCm38
MGSCv37586,441,049 - 86,494,608 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36587,086,585 - 87,140,032 (-)NCBIMGSCv36mm8
Celera583,243,963 - 83,297,482 (-)NCBICelera
Cytogenetic Map5E1NCBI
cM Map543.56NCBI
Cenpc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81422,342,910 - 22,401,522 (+)NCBIGRCr8
mRatBN7.21421,988,067 - 22,046,732 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1421,988,144 - 22,055,476 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1422,344,912 - 22,404,654 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01423,657,349 - 23,717,084 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01422,188,431 - 22,248,172 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01423,611,909 - 23,670,314 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1423,611,735 - 23,670,475 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01423,515,129 - 23,571,976 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41423,771,576 - 23,829,980 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11423,771,575 - 23,829,977 (+)NCBI
Celera1421,462,361 - 21,520,618 (+)NCBICelera
Cytogenetic Map14p21NCBI
Cenpc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554475,345,896 - 5,406,730 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554475,345,617 - 5,406,889 (+)NCBIChiLan1.0ChiLan1.0
CENPC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11358,013,218 - 58,091,347 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1358,013,212 - 58,231,200 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1357,928,845 - 58,006,993 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01358,634,688 - 58,702,538 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1358,634,844 - 58,702,350 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11358,350,980 - 58,428,821 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01357,841,062 - 57,919,053 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01358,850,883 - 58,929,219 (-)NCBIUU_Cfam_GSD_1.0
Cenpc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528518,357,663 - 18,414,077 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936582920,833 - 981,373 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936582920,852 - 978,167 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CENPC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl865,238,090 - 65,315,713 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1865,237,825 - 65,315,788 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2869,658,715 - 69,740,181 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Cenpc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247611,422,857 - 1,498,726 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000003236   ⟹   ENSCSAP00000001520
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl71,393,348 - 1,467,989 (+)Ensembl
RefSeq Acc Id: XM_007998583   ⟹   XP_007996774
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.171,393,338 - 1,464,189 (+)NCBI
Vero_WHO_p1.0NW_0236660661,480,301 - 1,552,594 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007998585   ⟹   XP_007996776
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.171,402,421 - 1,464,189 (+)NCBI
Vero_WHO_p1.0NW_0236660661,490,809 - 1,552,594 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037989399   ⟹   XP_037845327
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660661,480,301 - 1,552,594 (+)NCBI
RefSeq Acc Id: XM_037989400   ⟹   XP_037845328
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660661,480,606 - 1,552,594 (+)NCBI
Protein Sequences
Protein RefSeqs XP_007996774 (Get FASTA)   NCBI Sequence Viewer  
  XP_007996776 (Get FASTA)   NCBI Sequence Viewer  
  XP_037845327 (Get FASTA)   NCBI Sequence Viewer  
  XP_037845328 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000001520.1
RefSeq Acc Id: XP_007996774   ⟸   XM_007998583
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QYT1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007996776   ⟸   XM_007998585
- Peptide Label: isoform X3
- UniProtKB: A0A0D9QYT1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000001520   ⟸   ENSCSAT00000003236
RefSeq Acc Id: XP_037845327   ⟸   XM_037989399
- Peptide Label: isoform X2
- UniProtKB: A0A0D9QYT1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037845328   ⟸   XM_037989400
- Peptide Label: isoform X3
- UniProtKB: A0A0D9QYT1 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000005202 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000003236.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.10 UniProtKB/TrEMBL
InterPro CENP-C/Mif2/cnp3 UniProtKB/TrEMBL
  CENP-C_mid UniProtKB/TrEMBL
  CENP_C_N_dom UniProtKB/TrEMBL
  Mif2/CENP-C_cupin UniProtKB/TrEMBL
  RmlC-like_jellyroll UniProtKB/TrEMBL
  RmlC_Cupin_sf UniProtKB/TrEMBL
NCBI Gene CENPC ENTREZGENE
PANTHER CENTROMERE PROTEIN C UniProtKB/TrEMBL
  PTHR16684 UniProtKB/TrEMBL
Pfam CENP-C_C UniProtKB/TrEMBL
  CENP-C_mid UniProtKB/TrEMBL
  CENP_C_N UniProtKB/TrEMBL
Superfamily-SCOP SSF51182 UniProtKB/TrEMBL
UniProt A0A0D9QYT1 ENTREZGENE, UniProtKB/TrEMBL