CENPC (centromere protein C) - Rat Genome Database

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Gene: CENPC (centromere protein C) Sus scrofa
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Symbol: CENPC
Name: centromere protein C
RGD ID: 14167549
Description: ENCODES a protein that exhibits centromeric DNA binding (inferred); identical protein binding (inferred); INVOLVED IN chromosome segregation (inferred); kinetochore assembly (inferred); mitotic cell cycle (inferred); ASSOCIATED WITH CREST syndrome (ortholog); liver cirrhosis (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN condensed chromosome, centromeric region (inferred); inner kinetochore (inferred); kinetochore (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CENPC1; centromere protein C 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl865,238,090 - 65,315,713 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1865,237,825 - 65,315,788 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2869,658,715 - 69,740,181 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CENPC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl865,238,090 - 65,315,713 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1865,237,825 - 65,315,788 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2869,658,715 - 69,740,181 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CENPC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38467,468,762 - 67,545,503 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl467,468,762 - 67,545,503 (-)EnsemblGRCh38hg38GRCh38
GRCh37468,334,480 - 68,411,221 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36468,020,584 - 68,093,851 (-)NCBINCBI36Build 36hg18NCBI36
Build 34468,166,961 - 68,239,995NCBI
Celera465,800,619 - 65,873,659 (-)NCBICelera
Cytogenetic Map4q13.2NCBI
HuRef464,251,196 - 64,324,430 (-)NCBIHuRef
CHM1_1468,375,177 - 68,448,439 (-)NCBICHM1_1
T2T-CHM13v2.0470,911,881 - 70,988,601 (-)NCBIT2T-CHM13v2.0
Cenpc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39586,159,877 - 86,214,325 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl586,159,883 - 86,213,442 (-)EnsemblGRCm39 Ensembl
GRCm38586,012,018 - 86,065,962 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl586,012,024 - 86,065,583 (-)EnsemblGRCm38mm10GRCm38
MGSCv37586,441,049 - 86,494,608 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36587,086,585 - 87,140,032 (-)NCBIMGSCv36mm8
Celera583,243,963 - 83,297,482 (-)NCBICelera
Cytogenetic Map5E1NCBI
cM Map543.56NCBI
Cenpc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81422,342,910 - 22,401,522 (+)NCBIGRCr8
mRatBN7.21421,988,067 - 22,046,732 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1421,988,144 - 22,055,476 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1422,344,912 - 22,404,654 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01423,657,349 - 23,717,084 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01422,188,431 - 22,248,172 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01423,611,909 - 23,670,314 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1423,611,735 - 23,670,475 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01423,515,129 - 23,571,976 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41423,771,576 - 23,829,980 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11423,771,575 - 23,829,977 (+)NCBI
Celera1421,462,361 - 21,520,618 (+)NCBICelera
Cytogenetic Map14p21NCBI
Cenpc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554475,345,896 - 5,406,730 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554475,345,617 - 5,406,889 (+)NCBIChiLan1.0ChiLan1.0
CENPC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11358,013,218 - 58,091,347 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1358,013,212 - 58,231,200 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1357,928,845 - 58,006,993 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01358,634,688 - 58,702,538 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1358,634,844 - 58,702,350 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11358,350,980 - 58,428,821 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01357,841,062 - 57,919,053 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01358,850,883 - 58,929,219 (-)NCBIUU_Cfam_GSD_1.0
Cenpc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528518,357,663 - 18,414,077 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936582920,833 - 981,373 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936582920,852 - 978,167 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CENPC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.171,393,336 - 1,464,189 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl71,393,348 - 1,467,989 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660661,480,301 - 1,552,594 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cenpc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247611,422,857 - 1,498,726 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CENPC
1582 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000009769   ⟹   ENSSSCP00000009517
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl865,238,090 - 65,315,713 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000059921   ⟹   ENSSSCP00000043619
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl865,238,303 - 65,315,647 (-)Ensembl
RefSeq Acc Id: XM_003482404   ⟹   XP_003482452
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1865,237,825 - 65,315,788 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013978751   ⟹   XP_013834205
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1865,237,825 - 65,315,725 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021101386   ⟹   XP_020957045
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1865,238,122 - 65,315,725 (-)NCBI
Sequence:
RefSeq Acc Id: XP_003482452   ⟸   XM_003482404
- Peptide Label: isoform X1
- UniProtKB: F1RVF8 (UniProtKB/TrEMBL),   A0A4X1THD3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013834205   ⟸   XM_013978751
- Peptide Label: isoform X2
- UniProtKB: A0A287AIB3 (UniProtKB/TrEMBL),   A0A4X1THD8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020957045   ⟸   XM_021101386
- Peptide Label: isoform X3
- UniProtKB: A0A8D0KKK0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000009517   ⟸   ENSSSCT00000009769
Ensembl Acc Id: ENSSSCP00000043619   ⟸   ENSSSCT00000059921

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000008921 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015081033 UniProtKB/TrEMBL
  ENSSSCG00025047141 UniProtKB/TrEMBL
  ENSSSCG00030035479 UniProtKB/TrEMBL
  ENSSSCG00035026135 UniProtKB/TrEMBL
  ENSSSCG00045003097 UniProtKB/TrEMBL
  ENSSSCG00055025198 UniProtKB/TrEMBL
  ENSSSCG00060076990 UniProtKB/TrEMBL
  ENSSSCG00070009092 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000009769 ENTREZGENE
  ENSSSCT00000009769.5 UniProtKB/TrEMBL
  ENSSSCT00000059921 ENTREZGENE
  ENSSSCT00000059921.2 UniProtKB/TrEMBL
  ENSSSCT00015110428.1 UniProtKB/TrEMBL
  ENSSSCT00015110430.1 UniProtKB/TrEMBL
  ENSSSCT00015110437.1 UniProtKB/TrEMBL
  ENSSSCT00015110447.1 UniProtKB/TrEMBL
  ENSSSCT00015110456.1 UniProtKB/TrEMBL
  ENSSSCT00025064093.1 UniProtKB/TrEMBL
  ENSSSCT00025064418.1 UniProtKB/TrEMBL
  ENSSSCT00025064717.1 UniProtKB/TrEMBL
  ENSSSCT00025064972.1 UniProtKB/TrEMBL
  ENSSSCT00030049190.1 UniProtKB/TrEMBL
  ENSSSCT00035034460.1 UniProtKB/TrEMBL
  ENSSSCT00035034464.1 UniProtKB/TrEMBL
  ENSSSCT00035034481.1 UniProtKB/TrEMBL
  ENSSSCT00035034494.1 UniProtKB/TrEMBL
  ENSSSCT00045004971.1 UniProtKB/TrEMBL
  ENSSSCT00045004977.1 UniProtKB/TrEMBL
  ENSSSCT00045005004.1 UniProtKB/TrEMBL
  ENSSSCT00045005025.1 UniProtKB/TrEMBL
  ENSSSCT00055049787.1 UniProtKB/TrEMBL
  ENSSSCT00055049926.1 UniProtKB/TrEMBL
  ENSSSCT00055050083.1 UniProtKB/TrEMBL
  ENSSSCT00055050208.1 UniProtKB/TrEMBL
  ENSSSCT00060105802.1 UniProtKB/TrEMBL
  ENSSSCT00060105848.1 UniProtKB/TrEMBL
  ENSSSCT00070017652.1 UniProtKB/TrEMBL
  ENSSSCT00070017663.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.10 UniProtKB/TrEMBL
InterPro CENP-C/Mif2/cnp3 UniProtKB/TrEMBL
  CENP-C_mid UniProtKB/TrEMBL
  CENP_C_N_dom UniProtKB/TrEMBL
  Mif2/CENP-C_cupin UniProtKB/TrEMBL
  RmlC-like_jellyroll UniProtKB/TrEMBL
  RmlC_Cupin_sf UniProtKB/TrEMBL
KEGG Report ssc:100737668 UniProtKB/TrEMBL
NCBI Gene CENPC ENTREZGENE
PANTHER CENTROMERE PROTEIN C UniProtKB/TrEMBL
  PTHR16684 UniProtKB/TrEMBL
Pfam CENP-C_C UniProtKB/TrEMBL
  CENP-C_mid UniProtKB/TrEMBL
  CENP_C_N UniProtKB/TrEMBL
Superfamily-SCOP SSF51182 UniProtKB/TrEMBL
UniProt A0A287AIB3 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1THD3 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1THD8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0KKK0 ENTREZGENE
  A0A8D0QCZ1_PIG UniProtKB/TrEMBL
  A0A8D0QD91_PIG UniProtKB/TrEMBL
  A0A8D0QFI3_PIG UniProtKB/TrEMBL
  A0A8D0S8Z3_PIG UniProtKB/TrEMBL
  A0A8D0UFE6_PIG UniProtKB/TrEMBL
  A0A8D0UFE8_PIG UniProtKB/TrEMBL
  A0A8D0Z7A5_PIG UniProtKB/TrEMBL
  A0A8D1KPH2_PIG UniProtKB/TrEMBL
  A0A8D1RMP3_PIG UniProtKB/TrEMBL
  A0A8D1RV51_PIG UniProtKB/TrEMBL
  A0A8D1RYH7_PIG UniProtKB/TrEMBL
  A0A8D1UAW2_PIG UniProtKB/TrEMBL
  A0A8D1WY36_PIG UniProtKB/TrEMBL
  A0A8D2BVG7_PIG UniProtKB/TrEMBL
  F1RVF8 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:86546 ENTREZGENE