TNP1 (transition protein 1) - Rat Genome Database

Name: TNP1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: TNP1 (transition protein 1) Chlorocebus sabaeus

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Symbol:

TNP1

Name:

transition protein 1

RGD ID:

18497474

Description:

ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN spermatogenesis (ortholog); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN male germ cell nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

spermatid nuclear transition protein 1

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TNP1 (transition protein 1)	NCBI	Ortholog
Mus musculus (house mouse):	Tnp1 (transition protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Tnp1 (transition protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tnp1 (transition protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TNP1 (transition protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TNP1 (transition protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tnp1 (transition protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TNP1 (transition protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tnp1 (transition protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	102,703,116 - 102,703,747 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	102,703,325 - 102,703,691 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	96,709,921 - 96,711,971 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Neurodevelopmental Disorders (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell differentiation (IEA)

chromatin remodeling (IEA)

flagellated sperm motility (IEA)

heterochromatin formation (IEA)

negative regulation of DNA-templated transcription (IEA)

nucleosome disassembly (IEA)

positive regulation of protein processing (IEA)

sexual reproduction (IEA)

single strand break repair (IEA)

sperm DNA condensation (IEA)

spermatid development (IEA)

spermatid nucleus elongation (IEA)

spermatogenesis (IEA,ISO)

Cellular Component

chromosome (IEA)

male germ cell nucleus (IEA,ISO)

nucleosome (IEA)

nucleus (IEA)

Molecular Function

DNA binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

TNP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	102,703,116 - 102,703,747 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	102,703,325 - 102,703,691 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	96,709,921 - 96,711,971 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

TNP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	216,859,458 - 216,860,064 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	216,859,458 - 216,860,064 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	217,724,181 - 217,724,787 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	217,432,426 - 217,433,027 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	217,549,689 - 217,550,288	NCBI
Celera	2	211,492,069 - 211,492,670 (-)	NCBI		Celera
Cytogenetic Map	2	q35	NCBI
HuRef	2	209,578,223 - 209,578,824 (-)	NCBI		HuRef
CHM1_1	2	217,730,235 - 217,730,836 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	217,341,898 - 217,342,504 (-)	NCBI		T2T-CHM13v2.0

Tnp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	73,054,233 - 73,055,058 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	73,054,233 - 73,055,068 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	73,015,074 - 73,015,899 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	73,015,074 - 73,015,909 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	73,061,648 - 73,062,473 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	72,948,284 - 72,949,079 (-)	NCBI		MGSCv36	mm8
Celera	1	73,589,038 - 73,589,863 (-)	NCBI		Celera
Cytogenetic Map	1	C3	NCBI
cM Map	1	36.94	NCBI

Tnp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	82,043,669 - 82,044,278 (-)	NCBI		GRCr8
mRatBN7.2	9	74,594,463 - 74,595,072 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	74,594,466 - 74,595,274 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	83,049,184 - 83,049,793 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	88,178,079 - 88,178,688 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	86,564,825 - 86,565,434 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	80,294,837 - 80,295,446 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	80,294,840 - 80,295,446 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	80,066,299 - 80,066,908 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	72,397,750 - 72,398,359 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	72,544,732 - 72,545,341 (-)	NCBI
Celera	9	72,188,091 - 72,188,700 (-)	NCBI		Celera
Cytogenetic Map	9	q33	NCBI

Tnp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955453	16,387,527 - 16,388,890 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955453	16,387,897 - 16,388,513 (+)	NCBI	ChiLan1.0	ChiLan1.0

TNP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	119,489,569 - 119,490,175 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	119,504,535 - 119,505,141 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	104,122,748 - 104,123,349 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	222,723,606 - 222,724,212 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	222,723,606 - 222,724,212 (-)	Ensembl	panpan1.1		panPan2

TNP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	23,742,875 - 23,743,417 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	23,727,538 - 23,743,365 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1

Tnp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	172,120,406 - 172,121,032 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936586	504,864 - 505,447 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936586	504,864 - 505,447 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TNP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	119,037,496 - 119,038,105 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	119,037,492 - 119,038,099 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	131,800,371 - 131,801,028 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Tnp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624823	8,269,758 - 8,270,134 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	hemolymphoid system	mesenchyme	mesoderm	nervous system
32	17	17	17	32

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007966220	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038001550	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000007092 ⟹ ENSCSAP00000005278

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	10	102,703,325 - 102,703,691 (-)	Ensembl

RefSeq Acc Id:

XM_038001550 ⟹ XP_037857478

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666040	96,709,921 - 96,711,971 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_037857478	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000005278.1

Ensembl Acc Id:

ENSCSAP00000005278 ⟸ ENSCSAT00000007092

RefSeq Acc Id:

XP_037857478 ⟸ XM_038001550

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000009030	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000007092.1	UniProtKB/TrEMBL
InterPro	Nuclear_transition_prot1	UniProtKB/TrEMBL
	Nuclear_transition_prot1_CS	UniProtKB/TrEMBL
KEGG Report	csab:103217829	UniProtKB/TrEMBL
NCBI Gene	TNP1	ENTREZGENE
PANTHER	PTHR17486	UniProtKB/TrEMBL
	SPERMATID NUCLEAR TRANSITION PROTEIN 1	UniProtKB/TrEMBL
Pfam	TP1	UniProtKB/TrEMBL
PROSITE	TP1	UniProtKB/TrEMBL
UniProt	A0A0D9R9I9_CHLSB	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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