TRIAP1 (TP53 regulated inhibitor of apoptosis 1)

Gene: TRIAP1 (TP53 regulated inhibitor of apoptosis 1) Chlorocebus sabaeus

Analyze

Symbol:

TRIAP1

Name:

TP53 regulated inhibitor of apoptosis 1

RGD ID:

18481863

Description:

ENCODES a protein that exhibits p53 binding (ortholog); phosphatidic acid transfer activity (ortholog); INVOLVED IN cellular response to UV (ortholog); DNA damage response, signal transduction by p53 class mediator (ortholog); negative regulation of apoptotic process (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN mitochondrion (ortholog); nucleoplasm (ortholog); protein-containing complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

TP53-regulated inhibitor of apoptosis 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	115,798,472 - 115,800,906 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	115,798,862 - 115,800,840 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	129,299,222 - 129,301,650 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to UV (ISO)

DNA damage response, signal transduction by p53 class mediator (ISO)

intermembrane lipid transfer (IEA)

negative regulation of apoptotic process (ISO)

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (ISO)

negative regulation of release of cytochrome c from mitochondria (ISO)

phospholipid translocation (IEA)

phospholipid transport (ISO)

positive regulation of phospholipid transport (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of membrane lipid distribution (ISO)

Cellular Component

cytosol (IEA)

mitochondrial intermembrane space (IEA)

mitochondrion (ISO)

nucleoplasm (ISO)

nucleus (IEA)

protein-containing complex (ISO)

Molecular Function

p53 binding (ISO)

phosphatidic acid transfer activity (IEA,ISO)

protein binding (ISO)

References

Genomics

Comparative Map Data

TRIAP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	115,798,472 - 115,800,906 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	115,798,862 - 115,800,840 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	129,299,222 - 129,301,650 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

TRIAP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	120,443,964 - 120,446,384 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	120,443,964 - 120,446,384 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	120,881,767 - 120,884,187 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	119,366,147 - 119,368,598 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	12	120,516,476 - 120,518,927 (-)	NCBI		Celera
Cytogenetic Map	12	q24.31	NCBI
HuRef	12	117,890,554 - 117,893,005 (-)	NCBI		HuRef
CHM1_1	12	120,850,255 - 120,852,706 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	120,432,477 - 120,434,897 (-)	NCBI		T2T-CHM13v2.0

Triap1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	115,479,290 - 115,481,612 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	115,479,284 - 115,481,628 (+)	Ensembl		GRCm39 Ensembl
GRCm38	5	115,341,231 - 115,343,553 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	115,341,225 - 115,343,569 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	115,791,256 - 115,793,561 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	115,602,246 - 115,604,551 (+)	NCBI		MGSCv36	mm8
Celera	5	112,438,503 - 112,440,806 (+)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	56.06	NCBI

Triap1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	46,928,273 - 46,930,766 (-)	NCBI		GRCr8
mRatBN7.2	12	41,267,534 - 41,270,053 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	41,267,549 - 41,270,042 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	42,434,331 - 42,436,824 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	43,048,000 - 43,050,493 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	42,108,553 - 42,111,046 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	46,987,404 - 46,989,906 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	47,029,861 - 47,031,498 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	12	46,987,404 - 46,989,897 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	48,822,355 - 48,824,864 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	42,535,655 - 42,538,148 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	12	42,888,498 - 42,890,991 (-)	NCBI		Celera
Cytogenetic Map	12	q16	NCBI

Triap1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955455	11,195,399 - 11,198,402 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955455	11,195,399 - 11,198,402 (+)	NCBI	ChiLan1.0	ChiLan1.0

TRIAP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	128,512,268 - 128,514,721 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	128,508,645 - 128,511,098 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	118,025,599 - 118,028,045 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	121,400,063 - 121,402,506 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	121,400,063 - 121,402,506 (-)	Ensembl	panpan1.1		panPan2

TRIAP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	16,349,513 - 16,352,805 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	16,351,044 - 16,352,773 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	16,353,822 - 16,356,412 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	16,617,380 - 16,619,969 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	16,616,678 - 16,619,940 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	16,577,436 - 16,580,035 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	16,654,149 - 16,656,745 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	16,695,987 - 16,698,578 (-)	NCBI		UU_Cfam_GSD_1.0

Triap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	146,001,925 - 146,004,272 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936668	500,813 - 503,148 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936668	500,815 - 503,158 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TRIAP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	14	40,411,957 - 40,415,500 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

Triap1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624747	13,220,377 - 13,223,502 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium	36	1	42
Low		19	18
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008004942	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000000281 ⟹ ENSCSAP00000015774

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	11	115,798,862 - 115,800,840 (-)	Ensembl

RefSeq Acc Id:

XM_008004942 ⟹ XP_008003133

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	11	115,798,472 - 115,800,906 (-)	NCBI
Vero_WHO_p1.0	NW_023666037	129,299,222 - 129,301,650 (+)	NCBI

Sequence:

show sequence

CCAGCGACGCGCCTAAGAGTGATGACATCAGAGTGCGCTGCCGCCGCCGCCGACACCACTGTCG
CCATGAACAGTGTGGGGGAGGCATGCACGGACATGAAGCGCGAATACGACCAGTGCTTCAATCG
CTGGTTCGCCGAGAAGTTTCTCAAGGGGGACAGCTCCGGGGACCCGTGCACCGACCTCTTCAAG
CGCTACCAGCAGTGTGTTCAGAAAGCAATAAAGGAGAAAGAGATTCCTATTGAAGGATTGGAAT
TCATGGGCCATGGCAAAGAAAAGTCTGAAAATTCTTCTTGACCTTGACAGTCACCTTGAAGGAT
TTCTCAATCCAGAAATTGAGGACTCTGGATTTTTGTCAACTAAATCTGTGAACCTAGCCATCAG
ATTTGATAAGGAACTTAGGAGAGAGGAGTTTTATTTCCCCCTTTGATGTTTTCCTCTCAGTTGT
AAAAGATGAACTCTTTGAGATGATTTCTTACCTGCTGTGGCATCTGGCAGGAACTCAGTGTGCT
AAAATTGAACAATTTTTTGAGATTATGGTTGCAATACTTGGTGTGGAATCAGCTTTACATAAAT
ATACCTTGTATGCAAACGATGATAAACTAGTCAGGATGAGCAGAGCTGCCTGACCTCTTGATTT
CTGCTGCGAAAAACATATACACTGTACTGGGGTCATCGTTCATGAAAGCAATTGGTTAAGACCT
CTTTTTTTCTCTCAGGGAACTAATGCTCTGAAAAAGGATCTGGGCACAACAGTTTCAGTGAGTG
CTTTTGAGCACACTTTTATTTTTATATAGTAACTAATGGTTAAGATTGCTGGTGGCCTGGATTA
GCAAAGAGGAAGACAGCTTTTAACACAGTTCCCTGCCTTCACCAGAGGTGTCAGATTAAGATGT
GAAAGCTGCAAGAATGTTGCAATGACCACCATTTCAGAGCTCTCAGTGTGTAGTTCAGGAATTA
AGATACTTGGAATAGCTATGGAGGAAGAACCTAAATTGCAAAGATCTGCTATTGCCAGCTTTCA
ACCCAAGTCAGTGAATTGTCAACCTGCATATCCTTAAAATGCTGCATCTGGTTAAATGGTGGGT
GGGTGGGGTGGGAAGCTAAAGGTGCTGGCTTTATTTGCCTTGTTTACTCATCCTGCCCTGTAAT
TTCTGTAATCCTGAAGATGGAATAAATTGTAACATTTAGTTTCTATCATTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_008003133	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000015774
	ENSCSAP00000015774.1

RefSeq Acc Id:

XP_008003133 ⟸ XM_008004942

RefSeq Acc Id:

ENSCSAP00000015774 ⟸ ENSCSAT00000000281

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000002262	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000000281.1	UniProtKB/TrEMBL
InterPro	MDM35_apoptosis	UniProtKB/TrEMBL
NCBI Gene	TRIAP1	ENTREZGENE
PANTHER	PTHR46403	UniProtKB/TrEMBL
	TP53-REGULATED INHIBITOR OF APOPTOSIS 1	UniProtKB/TrEMBL
Pfam	UPF0203	UniProtKB/TrEMBL
PROSITE	CHCH	UniProtKB/TrEMBL
UniProt	A0A0D9S4I5_CHLSB	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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