KATNB1 (katanin regulatory subunit B1) - Rat Genome Database

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Gene: KATNB1 (katanin regulatory subunit B1) Chlorocebus sabaeus
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Symbol: KATNB1
Name: katanin regulatory subunit B1
RGD ID: 18479709
Description: ENCODES a protein that exhibits ATPase regulator activity (inferred); dynein complex binding (inferred); microtubule binding (inferred); INVOLVED IN microtubule severing (ortholog); positive regulation of apoptotic process (ortholog); positive regulation of neuron projection development (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); Chromosome 16q12 Duplication Syndrome (ortholog); developmental and epileptic encephalopathy (ortholog); FOUND IN axon (ortholog); growth cone (ortholog); midbody (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: katanin p80 WD40 repeat-containing subunit B1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1543,666,892 - 43,688,110 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl543,666,940 - 43,687,807 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604732,491,471 - 32,513,027 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
KATNB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1543,666,892 - 43,688,110 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl543,666,940 - 43,687,807 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604732,491,471 - 32,513,027 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
KATNB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381657,735,770 - 57,757,244 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1657,735,739 - 57,757,244 (+)EnsemblGRCh38hg38GRCh38
GRCh371657,769,682 - 57,791,156 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361656,327,161 - 56,348,663 (+)NCBINCBI36Build 36hg18NCBI36
Build 341656,328,617 - 56,348,657NCBI
Celera1642,266,969 - 42,288,421 (+)NCBICelera
Cytogenetic Map16q21NCBI
HuRef1643,636,584 - 43,658,036 (+)NCBIHuRef
CHM1_11659,176,440 - 59,197,887 (+)NCBICHM1_1
T2T-CHM13v2.01663,530,976 - 63,552,401 (+)NCBIT2T-CHM13v2.0
Katnb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39895,807,804 - 95,826,502 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl895,807,814 - 95,829,777 (+)EnsemblGRCm39 Ensembl
GRCm38895,081,175 - 95,099,874 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl895,081,186 - 95,103,149 (+)EnsemblGRCm38mm10GRCm38
MGSCv37897,605,101 - 97,623,774 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36897,970,330 - 97,989,003 (+)NCBIMGSCv36mm8
Celera899,407,232 - 99,425,928 (+)NCBICelera
Cytogenetic Map8C5NCBI
cM Map847.12NCBI
Katnb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8199,927,249 - 9,946,750 (-)NCBIGRCr8
mRatBN7.2199,921,216 - 9,940,853 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl199,921,219 - 9,940,650 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx199,885,262 - 9,902,647 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01910,652,103 - 10,669,488 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0199,938,944 - 9,956,376 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01910,340,027 - 10,360,319 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1910,340,307 - 10,360,310 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01910,320,130 - 10,339,578 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41910,355,488 - 10,373,010 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11910,360,314 - 10,377,836 (-)NCBI
Celera199,809,407 - 9,826,994 (-)NCBICelera
Cytogenetic Map19p13NCBI
Katnb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543315,345,246 - 15,366,039 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543315,345,246 - 15,365,986 (+)NCBIChiLan1.0ChiLan1.0
KATNB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21867,205,818 - 67,228,247 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11673,126,749 - 73,149,164 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01638,011,804 - 38,034,015 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11657,142,912 - 57,165,426 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1657,143,472 - 57,165,426 (+)Ensemblpanpan1.1panPan2
KATNB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1258,734,875 - 58,755,515 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl258,734,893 - 58,755,477 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha255,364,660 - 55,385,336 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0259,273,227 - 59,293,915 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl259,273,227 - 59,292,927 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1256,104,955 - 56,125,637 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0257,112,437 - 57,133,123 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0258,005,758 - 58,026,434 (-)NCBIUU_Cfam_GSD_1.0
Katnb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934949,831,461 - 49,851,830 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364759,738,195 - 9,757,614 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364759,737,974 - 9,757,614 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KATNB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl619,630,447 - 19,659,043 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1619,630,355 - 19,659,039 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2617,703,623 - 17,719,166 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Katnb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474628,360,730 - 28,381,673 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474628,360,461 - 28,381,545 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000002883   ⟹   ENSCSAP00000001173
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl543,666,940 - 43,687,807 (+)Ensembl
RefSeq Acc Id: XM_007993477   ⟹   XP_007991668
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1543,666,892 - 43,688,109 (+)NCBI
Vero_WHO_p1.0NW_02366604732,491,471 - 32,513,027 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007993479   ⟹   XP_007991670
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1543,667,019 - 43,688,109 (+)NCBI
Vero_WHO_p1.0NW_02366604732,491,471 - 32,512,866 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007993480   ⟹   XP_007991671
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1543,666,892 - 43,688,110 (+)NCBI
Vero_WHO_p1.0NW_02366604732,491,471 - 32,513,027 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007993481   ⟹   XP_007991672
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1543,675,589 - 43,688,109 (+)NCBI
Vero_WHO_p1.0NW_02366604732,491,471 - 32,504,311 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007991668 (Get FASTA)   NCBI Sequence Viewer  
  XP_007991670 (Get FASTA)   NCBI Sequence Viewer  
  XP_007991671 (Get FASTA)   NCBI Sequence Viewer  
  XP_007991672 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000001173.1
RefSeq Acc Id: XP_007991671   ⟸   XM_007993480
- Peptide Label: isoform X2
- UniProtKB: A0A0D9QXT4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007991668   ⟸   XM_007993477
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QXT4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007991670   ⟸   XM_007993479
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QXT4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007991672   ⟸   XM_007993481
- Peptide Label: isoform X3
Ensembl Acc Id: ENSCSAP00000001173   ⟸   ENSCSAT00000002883


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000004849 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000002883.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro G-protein_beta_WD-40_rep UniProtKB/TrEMBL
  Katanin_bsu1 UniProtKB/TrEMBL
  Katanin_C-terminal UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene KATNB1 ENTREZGENE
PANTHER KATANIN P80 SUBUNIT UniProtKB/TrEMBL
  KATANIN P80 WD40 REPEAT-CONTAINING SUBUNIT B1 UniProtKB/TrEMBL
Pfam Katanin_con80 UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A0D9QXT4 ENTREZGENE, UniProtKB/TrEMBL