Katnb1 (katanin regulatory subunit B1) - Rat Genome Database

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Gene: Katnb1 (katanin regulatory subunit B1) Heterocephalus glaber
Analyze
Symbol: Katnb1
Name: katanin regulatory subunit B1
RGD ID: 18910661
Description: ENCODES a protein that exhibits ATPase regulator activity (inferred); dynein complex binding (inferred); microtubule binding (inferred); INVOLVED IN microtubule severing (ortholog); positive regulation of apoptotic process (ortholog); positive regulation of neuron projection development (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); developmental and epileptic encephalopathy (ortholog); early infantile epileptic encephalopathy (ortholog); FOUND IN axon (ortholog); growth cone (ortholog); katanin complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: katanin p80 WD40 repeat-containing subunit B1; katanin p80 WD40-containing subunit B1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474628,360,730 - 28,381,673 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474628,360,461 - 28,381,545 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Katnb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474628,360,730 - 28,381,673 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474628,360,461 - 28,381,545 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
KATNB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381657,735,770 - 57,757,244 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1657,735,739 - 57,757,244 (+)EnsemblGRCh38hg38GRCh38
GRCh371657,769,682 - 57,791,156 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361656,327,161 - 56,348,663 (+)NCBINCBI36Build 36hg18NCBI36
Build 341656,328,617 - 56,348,657NCBI
Celera1642,266,969 - 42,288,421 (+)NCBICelera
Cytogenetic Map16q21NCBI
HuRef1643,636,584 - 43,658,036 (+)NCBIHuRef
CHM1_11659,176,440 - 59,197,887 (+)NCBICHM1_1
T2T-CHM13v2.01663,530,976 - 63,552,401 (+)NCBIT2T-CHM13v2.0
Katnb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39895,807,804 - 95,826,502 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl895,807,814 - 95,829,777 (+)EnsemblGRCm39 Ensembl
GRCm38895,081,175 - 95,099,874 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl895,081,186 - 95,103,149 (+)EnsemblGRCm38mm10GRCm38
MGSCv37897,605,101 - 97,623,774 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36897,970,330 - 97,989,003 (+)NCBIMGSCv36mm8
Celera899,407,232 - 99,425,928 (+)NCBICelera
Cytogenetic Map8C5NCBI
cM Map847.12NCBI
Katnb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8199,927,249 - 9,946,750 (-)NCBIGRCr8
mRatBN7.2199,921,216 - 9,940,853 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl199,921,219 - 9,940,650 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx199,885,262 - 9,902,647 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01910,652,103 - 10,669,488 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0199,938,944 - 9,956,376 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01910,340,027 - 10,360,319 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1910,340,307 - 10,360,310 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01910,320,130 - 10,339,578 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41910,355,488 - 10,373,010 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11910,360,314 - 10,377,836 (-)NCBI
Celera199,809,407 - 9,826,994 (-)NCBICelera
Cytogenetic Map19p13NCBI
Katnb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543315,345,246 - 15,366,039 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543315,345,246 - 15,365,986 (+)NCBIChiLan1.0ChiLan1.0
KATNB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21867,205,818 - 67,228,247 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11673,126,749 - 73,149,164 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01638,011,804 - 38,034,015 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11657,142,912 - 57,165,426 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1657,143,472 - 57,165,426 (+)Ensemblpanpan1.1panPan2
KATNB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1258,734,875 - 58,755,515 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl258,734,893 - 58,755,477 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha255,364,660 - 55,385,336 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0259,273,227 - 59,293,915 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl259,273,227 - 59,292,927 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1256,104,955 - 56,125,637 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0257,112,437 - 57,133,123 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0258,005,758 - 58,026,434 (-)NCBIUU_Cfam_GSD_1.0
Katnb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934949,831,461 - 49,851,830 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364759,738,195 - 9,757,614 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364759,737,974 - 9,757,614 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KATNB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl619,630,447 - 19,659,043 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1619,630,355 - 19,659,039 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2617,703,623 - 17,719,166 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KATNB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1543,666,892 - 43,688,110 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl543,666,940 - 43,687,807 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604732,491,471 - 32,513,027 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000018960   ⟹   ENSHGLP00000018773
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474628,360,730 - 28,381,673 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000018961   ⟹   ENSHGLP00000018774
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474628,360,730 - 28,379,988 (-)Ensembl
RefSeq Acc Id: XM_004843142   ⟹   XP_004843199
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474628,360,461 - 28,381,339 (-)NCBI
RefSeq Acc Id: XM_004843144   ⟹   XP_004843201
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474628,360,461 - 28,380,704 (-)NCBI
RefSeq Acc Id: XM_004843145   ⟹   XP_004843202
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474628,360,461 - 28,375,749 (-)NCBI
RefSeq Acc Id: XM_021256993   ⟹   XP_021112652
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474628,360,461 - 28,381,545 (-)NCBI
RefSeq Acc Id: XM_021256995   ⟹   XP_021112654
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474628,360,461 - 28,381,196 (-)NCBI
RefSeq Acc Id: XM_021256996   ⟹   XP_021112655
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474628,360,461 - 28,381,383 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021112652   ⟸   XM_021256993
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JDJ8 (UniProtKB/TrEMBL),   G5AUF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021112655   ⟸   XM_021256996
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JDJ8 (UniProtKB/TrEMBL),   G5AUF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004843199   ⟸   XM_004843142
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JDJ8 (UniProtKB/TrEMBL),   G5AUF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021112654   ⟸   XM_021256995
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JDJ8 (UniProtKB/TrEMBL),   G5AUF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004843201   ⟸   XM_004843144
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JDJ8 (UniProtKB/TrEMBL),   G5AUF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004843202   ⟸   XM_004843145
- Peptide Label: isoform X2
RefSeq Acc Id: ENSHGLP00000018773   ⟸   ENSHGLT00000018960
RefSeq Acc Id: ENSHGLP00000018774   ⟸   ENSHGLT00000018961


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013445 Ensembl, ENTREZGENE
  ENSHGLG00100018736 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000018960 ENTREZGENE
  ENSHGLT00000018961 ENTREZGENE
  ENSHGLT00100025810 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro G-protein_beta_WD-40_rep UniProtKB/TrEMBL
  Katanin_C-terminal UniProtKB/TrEMBL
  KTNB1 UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report hgl:101720378 UniProtKB/TrEMBL
NCBI Gene Katnb1 ENTREZGENE
PANTHER KATANIN P80 SUBUNIT UniProtKB/TrEMBL
  KATANIN P80 WD40 REPEAT-CONTAINING SUBUNIT B1 UniProtKB/TrEMBL
Pfam Katanin_con80 UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A0P6JDJ8 ENTREZGENE, UniProtKB/TrEMBL
  G5AUF5 ENTREZGENE, UniProtKB/TrEMBL