OAZ2 (ornithine decarboxylase antizyme 2) - Rat Genome Database

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Gene: OAZ2 (ornithine decarboxylase antizyme 2) Chlorocebus sabaeus
Analyze
Symbol: OAZ2
Name: ornithine decarboxylase antizyme 2
RGD ID: 18452604
Description: ENCODES a protein that exhibits ornithine decarboxylase inhibitor activity (inferred); INVOLVED IN negative regulation of polyamine transmembrane transport (inferred); positive regulation of intracellular protein transport (inferred); positive regulation of protein catabolic process (inferred); PARTICIPATES IN polyamine metabolic pathway; ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); nemaline myopathy 6 (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12618,881,776 - 18,897,043 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2618,881,831 - 18,895,915 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048122,525,688 - 122,552,998 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
OAZ2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12618,881,776 - 18,897,043 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2618,881,831 - 18,895,915 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048122,525,688 - 122,552,998 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
OAZ2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381564,687,574 - 64,703,281 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1564,687,573 - 64,703,281 (-)EnsemblGRCh38hg38GRCh38
GRCh371564,979,773 - 64,995,480 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361562,766,829 - 62,782,507 (-)NCBINCBI36Build 36hg18NCBI36
Build 341562,766,828 - 62,782,507NCBI
Celera1541,857,387 - 41,873,073 (-)NCBICelera
Cytogenetic Map15q22.31NCBI
HuRef1541,805,393 - 41,821,079 (-)NCBIHuRef
CHM1_11565,099,012 - 65,114,700 (-)NCBICHM1_1
T2T-CHM13v2.01562,496,796 - 62,512,500 (-)NCBIT2T-CHM13v2.0
Oaz2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39965,583,830 - 65,597,582 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl965,575,283 - 65,597,582 (+)EnsemblGRCm39 Ensembl
GRCm38965,676,548 - 65,690,300 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl965,668,001 - 65,690,300 (+)EnsemblGRCm38mm10GRCm38
MGSCv37965,524,355 - 65,538,107 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36965,474,596 - 65,488,303 (+)NCBIMGSCv36mm8
Celera962,907,100 - 62,920,974 (+)NCBICelera
Cytogenetic Map9CNCBI
cM Map935.45NCBI
Oaz2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8875,094,817 - 75,108,634 (+)NCBIGRCr8
mRatBN7.2866,199,694 - 66,213,513 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl866,199,706 - 66,231,453 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx871,712,921 - 71,726,768 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0869,985,952 - 69,999,801 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0867,855,137 - 67,868,970 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0871,216,011 - 71,229,788 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl871,216,178 - 71,228,713 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0870,899,391 - 70,913,165 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4869,935,001 - 69,948,824 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera865,590,922 - 65,604,738 (+)NCBICelera
Cytogenetic Map8q24NCBI
Oaz2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545010,790,829 - 10,802,276 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545010,790,629 - 10,803,411 (+)NCBIChiLan1.0ChiLan1.0
OAZ2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21653,935,449 - 53,951,162 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11558,106,841 - 58,122,555 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01543,629,712 - 43,645,426 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11561,918,402 - 61,934,042 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1561,919,532 - 61,933,821 (-)Ensemblpanpan1.1panPan2
OAZ2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13029,122,556 - 29,126,513 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3029,122,556 - 29,126,512 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3029,041,834 - 29,058,849 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03029,299,981 - 29,317,009 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3029,270,768 - 29,317,070 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13029,234,170 - 29,251,175 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03029,296,091 - 29,313,098 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03029,536,057 - 29,553,079 (-)NCBIUU_Cfam_GSD_1.0
Oaz2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640107,220,972 - 107,233,577 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647125,070,127 - 25,081,431 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647125,069,035 - 25,081,640 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OAZ2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1107,325,191 - 107,339,309 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11107,325,225 - 107,338,475 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21118,156,768 - 118,169,231 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Oaz2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247817,891,315 - 7,903,607 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247817,891,104 - 7,904,720 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000010647   ⟹   ENSCSAP00000008734
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2618,881,831 - 18,895,915 (+)Ensembl
RefSeq Acc Id: XM_038008838   ⟹   XP_037864766
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666048122,525,688 - 122,552,998 (-)NCBI
Protein Sequences
Protein RefSeqs XP_037864766 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000008734.1
Ensembl Acc Id: ENSCSAP00000008734   ⟸   ENSCSAT00000010647
RefSeq Acc Id: XP_037864766   ⟸   XM_038008838


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000012556 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000010647.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.630.60 UniProtKB/TrEMBL
InterPro Acyl_CoA_acyltransferase UniProtKB/TrEMBL
  ODC_AZ UniProtKB/TrEMBL
  ODC_AZ_sf UniProtKB/TrEMBL
KEGG Report csab:103245489 UniProtKB/TrEMBL
NCBI Gene OAZ2 ENTREZGENE
PANTHER PTHR10279 UniProtKB/TrEMBL
  PTHR10279:SF6 UniProtKB/TrEMBL
Pfam ODC_AZ UniProtKB/TrEMBL
PROSITE ODC_AZ UniProtKB/TrEMBL
Superfamily-SCOP SSF55729 UniProtKB/TrEMBL
UniProt A0A0D9RJE5_CHLSB UniProtKB/TrEMBL