NDST1 (N-deacetylase and N-sulfotransferase 1) - Rat Genome Database

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Gene: NDST1 (N-deacetylase and N-sulfotransferase 1) Chlorocebus sabaeus
Analyze
Symbol: NDST1
Name: N-deacetylase and N-sulfotransferase 1
RGD ID: 18448185
Description: ENCODES a protein that exhibits [heparan sulfate]-glucosamine N-sulfotransferase activity (inferred); deacetylase activity (inferred); heparan sulfate N-deacetylase activity (inferred); INVOLVED IN animal organ morphogenesis (ortholog); aorta development (ortholog); cardiac septum development (ortholog); ASSOCIATED WITH autosomal recessive intellectual developmental disorder 46 (ortholog); complex cortical dysplasia with other brain malformations (ortholog); congenital diaphragmatic hernia (ortholog); FOUND IN Golgi apparatus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12353,109,806 - 53,159,880 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2353,123,222 - 53,155,016 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603424,554,718 - 24,627,309 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NDST1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12353,109,806 - 53,159,880 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2353,123,222 - 53,155,016 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603424,554,718 - 24,627,309 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
NDST1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385150,497,779 - 150,558,211 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5150,485,818 - 150,558,211 (+)EnsemblGRCh38hg38GRCh38
GRCh375149,877,341 - 149,937,773 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365149,880,623 - 149,917,966 (+)NCBINCBI36Build 36hg18NCBI36
Build 345149,880,622 - 149,917,966NCBI
Celera5145,968,756 - 146,018,856 (+)NCBICelera
Cytogenetic Map5q33.1NCBI
HuRef5145,034,217 - 145,084,242 (+)NCBIHuRef
CHM1_15149,320,110 - 149,370,203 (+)NCBICHM1_1
T2T-CHM13v2.05151,034,321 - 151,094,757 (+)NCBIT2T-CHM13v2.0
Ndst1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391860,817,566 - 60,907,465 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1860,817,566 - 60,881,722 (-)EnsemblGRCm39 Ensembl
GRCm381860,684,494 - 60,749,035 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1860,684,494 - 60,748,650 (-)EnsemblGRCm38mm10GRCm38
MGSCv371860,845,617 - 60,873,043 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361860,811,332 - 60,838,758 (-)NCBIMGSCv36mm8
Celera1861,969,670 - 61,997,089 (-)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1834.38NCBI
Ndst1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81856,407,308 - 56,470,007 (-)NCBIGRCr8
mRatBN7.21854,136,887 - 54,199,545 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1854,140,779 - 54,178,191 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1856,229,512 - 56,266,941 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01856,944,111 - 56,981,540 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01854,764,697 - 54,802,107 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01855,951,497 - 56,014,107 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1855,955,389 - 55,992,885 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01855,189,496 - 55,226,905 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41856,638,891 - 56,677,831 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11856,711,122 - 56,750,063 (-)NCBI
Celera1852,295,217 - 52,332,793 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
Ndst1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554153,999,473 - 4,060,998 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554154,017,142 - 4,078,927 (-)NCBIChiLan1.0ChiLan1.0
NDST1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24145,713,778 - 145,787,281 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15143,854,440 - 143,926,827 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05145,910,993 - 145,982,933 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15151,918,667 - 151,986,668 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5151,936,357 - 151,986,668 (+)Ensemblpanpan1.1panPan2
NDST1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1458,580,231 - 58,639,750 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl458,532,148 - 58,640,191 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha458,347,429 - 58,405,535 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0459,061,802 - 59,119,959 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl459,061,147 - 59,090,976 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1458,850,372 - 58,908,502 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0458,966,408 - 59,022,929 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0459,495,800 - 59,553,938 (-)NCBIUU_Cfam_GSD_1.0
Ndst1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213142,839,583 - 142,921,891 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365044,413,549 - 4,454,109 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365044,413,549 - 4,495,933 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDST1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2151,489,521 - 151,522,749 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12151,433,925 - 151,525,909 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Ndst1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247749,758,809 - 9,821,309 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247749,758,459 - 9,821,309 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000009508   ⟹   ENSCSAP00000007622
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2353,123,222 - 53,155,016 (+)Ensembl
RefSeq Acc Id: XM_038005947   ⟹   XP_037861875
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603424,554,718 - 24,627,238 (-)NCBI
RefSeq Acc Id: XM_038005948   ⟹   XP_037861876
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603424,554,718 - 24,626,923 (-)NCBI
RefSeq Acc Id: XM_038005950   ⟹   XP_037861878
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603424,554,718 - 24,619,880 (-)NCBI
RefSeq Acc Id: XM_038005952   ⟹   XP_037861880
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603424,554,718 - 24,627,309 (-)NCBI
RefSeq Acc Id: XM_038005955   ⟹   XP_037861883
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603424,554,718 - 24,626,923 (-)NCBI
RefSeq Acc Id: XM_038005958   ⟹   XP_037861886
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603424,554,718 - 24,604,866 (-)NCBI
RefSeq Acc Id: XM_038005959   ⟹   XP_037861887
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603424,554,718 - 24,615,477 (-)NCBI
RefSeq Acc Id: XM_038005962   ⟹   XP_037861890
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603424,554,718 - 24,627,238 (-)NCBI
RefSeq Acc Id: XM_038005970   ⟹   XP_037861898
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603424,554,718 - 24,590,230 (-)NCBI
RefSeq Acc Id: XM_038005977   ⟹   XP_037861905
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603424,554,718 - 24,627,303 (-)NCBI
RefSeq Acc Id: XM_038005979   ⟹   XP_037861907
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603424,554,718 - 24,626,922 (-)NCBI
RefSeq Acc Id: XM_038005983   ⟹   XP_037861911
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603424,554,718 - 24,615,469 (-)NCBI
Ensembl Acc Id: ENSCSAP00000007622   ⟸   ENSCSAT00000009508
RefSeq Acc Id: XP_037861880   ⟸   XM_038005952
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RG83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037861905   ⟸   XM_038005977
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037861890   ⟸   XM_038005962
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037861875   ⟸   XM_038005947
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RG83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037861883   ⟸   XM_038005955
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RG83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037861876   ⟸   XM_038005948
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RG83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037861907   ⟸   XM_038005979
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037861878   ⟸   XM_038005950
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RG83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037861887   ⟸   XM_038005959
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RG83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037861911   ⟸   XM_038005983
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037861886   ⟸   XM_038005958
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RG83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037861898   ⟸   XM_038005970
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000011472 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009508.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro Heparan_SO4_deacetylase UniProtKB/TrEMBL
  NST/OST UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Sulfotransferase_dom UniProtKB/TrEMBL
KEGG Report csab:103244797 UniProtKB/TrEMBL
NCBI Gene NDST1 ENTREZGENE
PANTHER BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE/N-SULFOTRANSFERASE 1 UniProtKB/TrEMBL
  PTHR10605 UniProtKB/TrEMBL
Pfam HSNSD UniProtKB/TrEMBL
  Sulfotransfer_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0D9RG83 ENTREZGENE, UniProtKB/TrEMBL