IFT25 (intraflagellar transport 25) - Rat Genome Database

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Gene: IFT25 (intraflagellar transport 25) Chlorocebus sabaeus
Analyze
Symbol: IFT25
Name: intraflagellar transport 25
RGD ID: 18442956
Description: INVOLVED IN cilium assembly (ortholog); heart development (ortholog); left/right axis specification (ortholog); ASSOCIATED WITH genetic disease (ortholog); renal agenesis (ortholog); FOUND IN intraciliary transport particle B (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: heat shock protein family B (small) member 11; HSPB11; intraflagellar transport protein 25 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12078,988,285 - 79,012,815 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2078,991,285 - 79,013,157 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603338,246,326 - 38,294,860 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
IFT25
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12078,988,285 - 79,012,815 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2078,991,285 - 79,013,157 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603338,246,326 - 38,294,860 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
IFT25
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38153,911,576 - 53,946,305 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl153,916,574 - 53,945,699 (-)EnsemblGRCh38hg38GRCh38
GRCh37154,382,246 - 54,411,978 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36154,159,822 - 54,183,876 (-)NCBINCBI36Build 36hg18NCBI36
Build 34154,099,255 - 54,123,290NCBI
Celera152,674,924 - 52,698,976 (-)NCBICelera
Cytogenetic Map1p32.3NCBI
HuRef152,502,957 - 52,527,009 (-)NCBIHuRef
CHM1_1154,503,607 - 54,527,658 (-)NCBICHM1_1
T2T-CHM13v2.0153,793,420 - 53,829,213 (-)NCBIT2T-CHM13v2.0
Ift25
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394107,110,889 - 107,137,135 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4107,110,790 - 107,137,135 (+)EnsemblGRCm39 Ensembl
GRCm384107,253,593 - 107,284,497 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4107,253,593 - 107,279,938 (+)EnsemblGRCm38mm10GRCm38
MGSCv374106,926,539 - 106,952,493 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364106,751,863 - 106,777,870 (+)NCBIMGSCv36mm8
Celera4105,616,287 - 105,642,404 (+)NCBICelera
Cytogenetic Map4C7NCBI
cM Map450.18NCBI
Ift25
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85127,264,450 - 127,291,225 (+)NCBIGRCr8
mRatBN7.25122,035,588 - 122,062,421 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5122,035,581 - 122,062,421 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5124,655,833 - 124,682,302 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05126,378,853 - 126,405,322 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05126,430,167 - 126,456,636 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05126,856,128 - 126,882,913 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5126,856,705 - 126,882,909 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05130,705,454 - 130,732,196 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45128,343,754 - 128,372,557 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5120,781,816 - 120,808,240 (+)NCBICelera
Cytogenetic Map5q34NCBI
Ift25
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554645,299,534 - 5,324,136 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554645,299,206 - 5,324,136 (+)NCBIChiLan1.0ChiLan1.0
IFT25
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21172,890,216 - 172,921,823 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11172,031,004 - 172,062,611 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0153,190,015 - 53,220,115 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1154,790,168 - 54,814,281 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl154,785,390 - 54,814,281 (-)Ensemblpanpan1.1panPan2
IFT25
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1555,042,926 - 55,070,204 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl555,042,911 - 55,070,106 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha555,109,093 - 55,136,885 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0555,230,322 - 55,258,147 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1555,224,710 - 55,252,489 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0555,114,277 - 55,142,368 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0555,504,027 - 55,531,800 (+)NCBIUU_Cfam_GSD_1.0
Ift25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505868,201,368 - 68,227,578 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365227,188,716 - 7,216,297 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365227,188,752 - 7,214,926 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IFT25
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6158,338,645 - 158,366,185 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16158,338,584 - 158,397,121 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26146,039,023 - 146,098,648 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Ift25
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624934543,847 - 568,122 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624934533,112 - 567,896 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 18 24
Low 18 20 36
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000017237   ⟹   ENSCSAP00000016719
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2078,991,285 - 79,013,157 (+)Ensembl
RefSeq Acc Id: XM_007978674   ⟹   XP_007976865
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12078,988,285 - 79,012,815 (+)NCBI
Vero_WHO_p1.0NW_02366603338,270,297 - 38,294,860 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038000263   ⟹   XP_037856191
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603338,246,326 - 38,294,088 (-)NCBI
RefSeq Acc Id: XM_038000264   ⟹   XP_037856192
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603338,270,297 - 38,294,081 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007976865 (Get FASTA)   NCBI Sequence Viewer  
  XP_037856191 (Get FASTA)   NCBI Sequence Viewer  
  XP_037856192 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000016719.1
Reference Protein Sequences
RefSeq Acc Id: XP_007976865   ⟸   XM_007978674
- Peptide Label: isoform X3
RefSeq Acc Id: ENSCSAP00000016719   ⟸   ENSCSAT00000017237
RefSeq Acc Id: XP_037856191   ⟸   XM_038000263
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037856192   ⟸   XM_038000264
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S780 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000001296 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000017237.1 UniProtKB/TrEMBL
Gene3D-CATH Galactose-binding domain-like UniProtKB/TrEMBL
InterPro FA58C UniProtKB/TrEMBL
  Galactose-bd-like_sf UniProtKB/TrEMBL
  IFT25 UniProtKB/TrEMBL
KEGG Report csab:103224784 UniProtKB/TrEMBL
NCBI Gene HSPB11 ENTREZGENE
PANTHER INTRAFLAGELLAR TRANSPORT PROTEIN 25 HOMOLOG UniProtKB/TrEMBL
  PTHR33906 UniProtKB/TrEMBL
Pfam F5_F8_type_C UniProtKB/TrEMBL
Superfamily-SCOP SSF49785 UniProtKB/TrEMBL
UniProt A0A0D9S780 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-03-29 IFT25  intraflagellar transport 25  HSPB11  intraflagellar transport 25  Symbol and/or name change 5135510 APPROVED
2022-12-13 HSPB11  intraflagellar transport 25  HSPB11  heat shock protein family B (small) member 11  Symbol and/or name change 5135510 APPROVED