SLC6A18 (solute carrier family 6 member 18) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: SLC6A18 (solute carrier family 6 member 18) Chlorocebus sabaeus
Analyze
Symbol: SLC6A18
Name: solute carrier family 6 member 18
RGD ID: 18442491
Description: ENCODES a protein that exhibits amino acid transmembrane transporter activity (ortholog); INVOLVED IN amino acid transmembrane transport (ortholog); amino acid transport (ortholog); hyperosmotic response (ortholog); ASSOCIATED WITH autosomal dominant dyskeratosis congenita 2 (ortholog); dopamine transporter deficiency syndrome (ortholog); hypertension (ortholog); FOUND IN apical plasma membrane (inferred); brush border membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inactive sodium-dependent neutral amino acid transporter B(0)AT3; sodium-dependent neutral amino acid transporter B(0)AT3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.141,054,353 - 1,079,478 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl41,057,136 - 1,075,426 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605435,619,384 - 35,641,717 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC6A18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.141,054,353 - 1,079,478 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl41,057,136 - 1,075,426 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605435,619,384 - 35,641,717 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SLC6A18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3851,225,381 - 1,246,189 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl51,225,381 - 1,246,189 (+)EnsemblGRCh38hg38GRCh38
GRCh3751,225,496 - 1,246,304 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3651,278,470 - 1,299,303 (+)NCBINCBI36Build 36hg18NCBI36
Build 3451,278,469 - 1,299,303NCBI
Celera51,262,353 - 1,283,111 (+)NCBICelera
Cytogenetic Map5p15.33NCBI
HuRef51,206,768 - 1,227,774 (+)NCBIHuRef
CHM1_151,225,356 - 1,246,130 (+)NCBICHM1_1
T2T-CHM13v2.051,132,355 - 1,153,096 (+)NCBIT2T-CHM13v2.0
Slc6a18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391373,809,869 - 73,826,142 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1373,809,871 - 73,826,142 (-)EnsemblGRCm39 Ensembl
GRCm381373,661,750 - 73,678,023 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1373,661,752 - 73,678,023 (-)EnsemblGRCm38mm10GRCm38
MGSCv371373,799,198 - 73,815,471 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361374,130,039 - 74,144,003 (-)NCBIMGSCv36mm8
Celera1375,990,742 - 76,006,978 (-)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1340.13NCBI
Slc6a18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8131,436,577 - 31,450,478 (+)NCBIGRCr8
mRatBN7.2129,607,288 - 29,621,925 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl129,608,077 - 29,621,925 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx129,409,233 - 29,423,054 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0135,409,083 - 35,422,904 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,609,861 - 29,623,682 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0132,221,679 - 32,235,599 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl132,221,636 - 32,236,051 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0133,646,546 - 33,660,461 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4130,415,234 - 30,429,059 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1130,418,178 - 30,432,004 (+)NCBI
Celera128,256,104 - 28,269,929 (+)NCBICelera
Cytogenetic Map1p11NCBI
Slc6a18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955504634,665 - 644,576 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955504634,615 - 644,667 (+)NCBIChiLan1.0ChiLan1.0
SLC6A18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v241,485,506 - 1,507,595 (+)NCBINHGRI_mPanPan1-v2
PanPan1.1 Ensembl51,272,746 - 1,293,181 (+)Ensemblpanpan1.1panPan2
SLC6A18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13411,312,172 - 11,327,493 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3411,290,166 - 11,327,505 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3415,817,657 - 15,837,358 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03411,208,459 - 11,228,159 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3411,190,836 - 11,228,161 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13411,259,258 - 11,278,952 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03411,243,187 - 11,258,500 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03411,454,210 - 11,469,522 (-)NCBIUU_Cfam_GSD_1.0
Slc6a18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213244,336,037 - 244,351,884 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936815497,396 - 513,175 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936815497,465 - 513,089 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC6A18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1679,277,696 - 79,292,530 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11679,278,126 - 79,292,463 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21685,936,688 - 85,951,025 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Slc6a18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624751608,766 - 619,213 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624751608,834 - 617,995 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
1 1 17 18 18

Sequence


Ensembl Acc Id: ENSCSAT00000015486   ⟹   ENSCSAP00000013425
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl41,057,136 - 1,075,426 (+)Ensembl
RefSeq Acc Id: XM_007961133   ⟹   XP_007959324
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.141,054,353 - 1,075,460 (+)NCBI
Vero_WHO_p1.0NW_02366605435,619,384 - 35,641,717 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007959324 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000013425
  ENSCSAP00000013425.1
RefSeq Acc Id: XP_007959324   ⟸   XM_007961133
- UniProtKB: A0A0D9RXT6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000013425   ⟸   ENSCSAT00000015486


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000017392 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000015486.1 UniProtKB/TrEMBL
InterPro B0AT3_SLC6sbd UniProtKB/TrEMBL
  Na/ntran_symport UniProtKB/TrEMBL
  Neutral_aa_SLC6 UniProtKB/TrEMBL
  SNS_sf UniProtKB/TrEMBL
NCBI Gene SLC6A18 ENTREZGENE
PANTHER INACTIVE SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT3 UniProtKB/TrEMBL
  PTHR11616 UniProtKB/TrEMBL
Pfam SNF UniProtKB/TrEMBL
PRINTS NANEUSMPORT UniProtKB/TrEMBL
  ORPHTRNSPORT UniProtKB/TrEMBL
PROSITE NA_NEUROTRAN_SYMP_1 UniProtKB/TrEMBL
  NA_NEUROTRAN_SYMP_2 UniProtKB/TrEMBL
  NA_NEUROTRAN_SYMP_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF161070 UniProtKB/TrEMBL
UniProt A0A0D9RXT6 ENTREZGENE, UniProtKB/TrEMBL