SLC6A18 (solute carrier family 6 member 18) - Rat Genome Database

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Gene: SLC6A18 (solute carrier family 6 member 18) Sus scrofa
Analyze
Symbol: SLC6A18
Name: solute carrier family 6 member 18
RGD ID: 14291813
Description: ENCODES a protein that exhibits amino acid transmembrane transporter activity (ortholog); INVOLVED IN amino acid transmembrane transport (ortholog); amino acid transport (ortholog); hyperosmotic response (ortholog); ASSOCIATED WITH autosomal dominant dyskeratosis congenita 2 (ortholog); dopamine transporter deficiency syndrome (ortholog); genetic disease (ortholog); FOUND IN apical plasma membrane (inferred); brush border membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sodium-dependent neutral amino acid transporter B(0)AT3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1679,277,696 - 79,292,530 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11679,278,126 - 79,292,463 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21685,936,688 - 85,951,025 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC6A18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1679,277,696 - 79,292,530 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11679,278,126 - 79,292,463 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21685,936,688 - 85,951,025 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC6A18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3851,225,381 - 1,246,189 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl51,225,381 - 1,246,189 (+)EnsemblGRCh38hg38GRCh38
GRCh3751,225,496 - 1,246,304 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3651,278,470 - 1,299,303 (+)NCBINCBI36Build 36hg18NCBI36
Build 3451,278,469 - 1,299,303NCBI
Celera51,262,353 - 1,283,111 (+)NCBICelera
Cytogenetic Map5p15.33NCBI
HuRef51,206,768 - 1,227,774 (+)NCBIHuRef
CHM1_151,225,356 - 1,246,130 (+)NCBICHM1_1
T2T-CHM13v2.051,132,355 - 1,153,096 (+)NCBIT2T-CHM13v2.0
Slc6a18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391373,809,869 - 73,826,142 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1373,809,871 - 73,826,142 (-)EnsemblGRCm39 Ensembl
GRCm381373,661,750 - 73,678,023 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1373,661,752 - 73,678,023 (-)EnsemblGRCm38mm10GRCm38
MGSCv371373,799,198 - 73,815,471 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361374,130,039 - 74,144,003 (-)NCBIMGSCv36mm8
Celera1375,990,742 - 76,006,978 (-)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1340.13NCBI
Slc6a18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8131,436,577 - 31,450,478 (+)NCBIGRCr8
mRatBN7.2129,607,288 - 29,621,925 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl129,608,077 - 29,621,925 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx129,409,233 - 29,423,054 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0135,409,083 - 35,422,904 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,609,861 - 29,623,682 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0132,221,679 - 32,235,599 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl132,221,636 - 32,236,051 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0133,646,546 - 33,660,461 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4130,415,234 - 30,429,059 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1130,418,178 - 30,432,004 (+)NCBI
Celera128,256,104 - 28,269,929 (+)NCBICelera
Cytogenetic Map1p11NCBI
Slc6a18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955504634,665 - 644,576 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955504634,615 - 644,667 (+)NCBIChiLan1.0ChiLan1.0
SLC6A18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v241,485,506 - 1,507,595 (+)NCBINHGRI_mPanPan1-v2
PanPan1.1 Ensembl51,272,746 - 1,293,181 (+)Ensemblpanpan1.1panPan2
SLC6A18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13411,312,172 - 11,327,493 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3411,290,166 - 11,327,505 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3415,817,657 - 15,837,358 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03411,208,459 - 11,228,159 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3411,190,836 - 11,228,161 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13411,259,258 - 11,278,952 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03411,243,187 - 11,258,500 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03411,454,210 - 11,469,522 (-)NCBIUU_Cfam_GSD_1.0
Slc6a18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213244,336,037 - 244,351,884 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936815497,396 - 513,175 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936815497,465 - 513,089 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC6A18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.141,054,353 - 1,079,478 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl41,057,136 - 1,075,426 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605435,619,384 - 35,641,717 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc6a18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624751608,766 - 619,213 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624751608,834 - 617,995 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC6A18
291 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system renal system
High
Medium 2
Low
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000018635   ⟹   ENSSSCP00000018134
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1679,278,129 - 79,292,503 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000065691   ⟹   ENSSSCP00000054937
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1679,277,696 - 79,292,446 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000102624   ⟹   ENSSSCP00000075014
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1679,279,347 - 79,292,530 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000104750   ⟹   ENSSSCP00000078379
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1679,279,573 - 79,288,532 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000105235   ⟹   ENSSSCP00000079481
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1679,279,573 - 79,289,282 (-)Ensembl
RefSeq Acc Id: XM_005672625   ⟹   XP_005672682
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11679,278,126 - 79,292,463 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005672626   ⟹   XP_005672683
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11679,278,128 - 79,292,463 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013984949   ⟹   XP_013840403
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11679,278,126 - 79,292,463 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_013840403   ⟸   XM_013984949
- Peptide Label: isoform X2
- UniProtKB: A0A287BF36 (UniProtKB/TrEMBL),   A0A8D1J423 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005672682   ⟸   XM_005672625
- Peptide Label: isoform X1
- UniProtKB: A0A287BF36 (UniProtKB/TrEMBL),   A0A8D1J423 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005672683   ⟸   XM_005672626
- Peptide Label: isoform X3
- UniProtKB: A0A287BF36 (UniProtKB/TrEMBL),   A0A8D1J423 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000054937   ⟸   ENSSSCT00000065691
RefSeq Acc Id: ENSSSCP00000018134   ⟸   ENSSSCT00000018635
RefSeq Acc Id: ENSSSCP00000075014   ⟸   ENSSSCT00000102624
RefSeq Acc Id: ENSSSCP00000079481   ⟸   ENSSSCT00000105235
RefSeq Acc Id: ENSSSCP00000078379   ⟸   ENSSSCT00000104750


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000017117 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015056963 UniProtKB/TrEMBL
  ENSSSCG00025034844 UniProtKB/TrEMBL
  ENSSSCG00030033392 UniProtKB/TrEMBL
  ENSSSCG00035007171 UniProtKB/TrEMBL
  ENSSSCG00040050548 UniProtKB/TrEMBL
  ENSSSCG00045034046 UniProtKB/TrEMBL
  ENSSSCG00050053061 UniProtKB/TrEMBL
  ENSSSCG00055016494 UniProtKB/TrEMBL
  ENSSSCG00060012251 UniProtKB/TrEMBL
  ENSSSCG00065076412 UniProtKB/TrEMBL
  ENSSSCG00070009915 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000018635 ENTREZGENE
  ENSSSCT00000018635.4 UniProtKB/TrEMBL
  ENSSSCT00000065691.3 UniProtKB/TrEMBL
  ENSSSCT00000102624.1 UniProtKB/TrEMBL
  ENSSSCT00000104750.1 UniProtKB/TrEMBL
  ENSSSCT00000105235.1 UniProtKB/TrEMBL
  ENSSSCT00015075884.1 UniProtKB/TrEMBL
  ENSSSCT00015076006.1 UniProtKB/TrEMBL
  ENSSSCT00025047954.1 UniProtKB/TrEMBL
  ENSSSCT00025048119.1 UniProtKB/TrEMBL
  ENSSSCT00030046752.1 UniProtKB/TrEMBL
  ENSSSCT00030047042.1 UniProtKB/TrEMBL
  ENSSSCT00030047090.1 UniProtKB/TrEMBL
  ENSSSCT00030047131.1 UniProtKB/TrEMBL
  ENSSSCT00035008922.1 UniProtKB/TrEMBL
  ENSSSCT00035008927.1 UniProtKB/TrEMBL
  ENSSSCT00035008936.1 UniProtKB/TrEMBL
  ENSSSCT00040070971.1 UniProtKB/TrEMBL
  ENSSSCT00040071453.1 UniProtKB/TrEMBL
  ENSSSCT00040071602.1 UniProtKB/TrEMBL
  ENSSSCT00040071946.1 UniProtKB/TrEMBL
  ENSSSCT00045059118.1 UniProtKB/TrEMBL
  ENSSSCT00045059268.1 UniProtKB/TrEMBL
  ENSSSCT00045059342.1 UniProtKB/TrEMBL
  ENSSSCT00045059464.1 UniProtKB/TrEMBL
  ENSSSCT00050072286.1 UniProtKB/TrEMBL
  ENSSSCT00050072307.1 UniProtKB/TrEMBL
  ENSSSCT00050072318.1 UniProtKB/TrEMBL
  ENSSSCT00055033213.1 UniProtKB/TrEMBL
  ENSSSCT00055033333.1 UniProtKB/TrEMBL
  ENSSSCT00055033417.1 UniProtKB/TrEMBL
  ENSSSCT00055033530.1 UniProtKB/TrEMBL
  ENSSSCT00060016092.1 UniProtKB/TrEMBL
  ENSSSCT00060016115.1 UniProtKB/TrEMBL
  ENSSSCT00060016124.1 UniProtKB/TrEMBL
  ENSSSCT00065105722.1 UniProtKB/TrEMBL
  ENSSSCT00065105764.1 UniProtKB/TrEMBL
  ENSSSCT00065105787.1 UniProtKB/TrEMBL
  ENSSSCT00065105807.1 UniProtKB/TrEMBL
  ENSSSCT00070019256.1 UniProtKB/TrEMBL
  ENSSSCT00070019267.1 UniProtKB/TrEMBL
InterPro Na/ntran_symport UniProtKB/TrEMBL
  Neutral_aa_SLC6 UniProtKB/TrEMBL
  SNS_sf UniProtKB/TrEMBL
NCBI Gene SLC6A18 ENTREZGENE
PANTHER INACTIVE SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT3 UniProtKB/TrEMBL
  PTHR11616 UniProtKB/TrEMBL
Pfam SNF UniProtKB/TrEMBL
PRINTS NANEUSMPORT UniProtKB/TrEMBL
  ORPHTRNSPORT UniProtKB/TrEMBL
PROSITE NA_NEUROTRAN_SYMP_1 UniProtKB/TrEMBL
  NA_NEUROTRAN_SYMP_2 UniProtKB/TrEMBL
  NA_NEUROTRAN_SYMP_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF161070 UniProtKB/TrEMBL
UniProt A0A287BF36 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1THB2_PIG UniProtKB/TrEMBL
  A0A4X1TJ47_PIG UniProtKB/TrEMBL
  A0A8D0UQ22_PIG UniProtKB/TrEMBL
  A0A8D1F264_PIG UniProtKB/TrEMBL
  A0A8D1J423 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1KEK9_PIG UniProtKB/TrEMBL
  A0A8D1MZ81_PIG UniProtKB/TrEMBL
  A0A8D1QUX3_PIG UniProtKB/TrEMBL
  A0A8D1QY33_PIG UniProtKB/TrEMBL
  A0A8D1R031_PIG UniProtKB/TrEMBL
  A0A8D1R0G9_PIG UniProtKB/TrEMBL
  A0A8W4F738_PIG UniProtKB/TrEMBL
  A0A8W4FG26_PIG UniProtKB/TrEMBL
  A0A8W4FJT1_PIG UniProtKB/TrEMBL
  F1S028_PIG UniProtKB/TrEMBL
VGNC ID VGNC:93159 ENTREZGENE