OTUD7A (OTU deubiquitinase 7A) - Rat Genome Database

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Gene: OTUD7A (OTU deubiquitinase 7A) Chlorocebus sabaeus
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Symbol: OTUD7A
Name: OTU deubiquitinase 7A
RGD ID: 18413505
Description: ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); INVOLVED IN protein K11-linked deubiquitination (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); chromosome 15q11.2 deletion syndrome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: OTU domain-containing protein 7A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12650,842,957 - 51,213,515 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604889,610,045 - 89,983,865 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 11 of 11 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
OTUD7AGreen Monkeyautism spectrum disorder  ISOOTUD7A (Homo sapiens)8554872ClinVar Annotator: match by term: Autism spectrum disorderClinVarPMID:19050728 more ...
OTUD7AGreen Monkeyautistic disorder  ISOOTUD7A (Homo sapiens)8554872ClinVar more ...ClinVarPMID:21681106 and PMID:30208311
OTUD7AGreen Monkeychromosome 15q11.2 deletion syndrome  ISOOTUD7A (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome 15q11-q13 duplication syndromeClinVar 
OTUD7AGreen Monkeychromosome 15q13.3 microdeletion syndrome  ISOOTUD7A (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome 15q13.3 microdeletion syndromeClinVarPMID:31690835
OTUD7AGreen Monkeycolorectal cancer  ISOOTUD7A (Homo sapiens)8554872ClinVar Annotator: match by term: Familial colorectal cancerClinVarPMID:22561515 more ...
OTUD7AGreen Monkeylanguage disorder  ISOOTUD7A (Homo sapiens)8554872ClinVar Annotator: match by term: Language disorderClinVarPMID:31997314
OTUD7AGreen Monkeylearning disability  ISOOTUD7A (Homo sapiens)8554872ClinVar Annotator: match by term: Specific learning disabilityClinVarPMID:31997314
OTUD7AGreen MonkeyNEURODEVELOPMENTAL DISORDER WITH HYPOTONIA AND SEIZURES  ISOOTUD7A (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
OTUD7AGreen MonkeyNeurodevelopmental Disorders  ISOOTUD7A (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
OTUD7AGreen Monkeynon-syndromic intellectual disability  ISOOTUD7A (Homo sapiens)8554872ClinVar Annotator: match by term: Non-syndromic intellectual disabilityClinVarPMID:25741868
OTUD7AGreen Monkeyschizophrenia  ISOOTUD7A (Homo sapiens)8554872ClinVar Annotator: match by term: SchizophreniaClinVarPMID:21681106 and PMID:30208311
1 to 11 of 11 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
OTUD7AGreen MonkeyNEURODEVELOPMENTAL DISORDER WITH HYPOTONIA AND SEIZURES  ISOOTUD7A (Homo sapiens)7240710 OMIM 


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
OTUD7AGreen Monkeyprotein K11-linked deubiquitination involved_inISOOTUD7A (Homo sapiens)9068941 PMID:23827681UniProtPMID:23827681

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
OTUD7AGreen Monkeycysteine-type deubiquitinase activity enablesISOOTUD7A (Homo sapiens)9068941 PMID:23827681UniProtPMID:23827681

PMID:22301074   PMID:30032202  



OTUD7A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12650,842,957 - 51,213,515 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604889,610,045 - 89,983,865 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
OTUD7A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381531,475,398 - 31,870,673 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1531,475,398 - 31,870,789 (-)EnsemblGRCh38hg38GRCh38
GRCh371531,767,601 - 32,162,876 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361529,562,621 - 29,734,834 (-)NCBINCBI36Build 36hg18NCBI36
Build 341529,562,620 - 29,734,834NCBI
Celera159,500,530 - 9,586,701 (-)NCBICelera
Cytogenetic Map15q13.3NCBI
HuRef158,953,038 - 9,124,721 (-)NCBIHuRef
CHM1_11531,766,251 - 31,937,781 (-)NCBICHM1_1
T2T-CHM13v2.01529,269,748 - 29,664,824 (-)NCBIT2T-CHM13v2.0
Otud7a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39763,094,493 - 63,415,980 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl763,094,499 - 63,408,776 (+)EnsemblGRCm39 Ensembl
GRCm38763,444,745 - 63,766,232 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl763,444,751 - 63,759,028 (+)EnsemblGRCm38mm10GRCm38
MGSCv37770,589,658 - 70,903,913 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36763,323,722 - 63,637,977 (+)NCBIMGSCv36mm8
Celera760,886,403 - 61,203,588 (+)NCBICelera
Cytogenetic Map7CNCBI
cM Map734.52NCBI
Otud7a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81126,476,275 - 126,800,037 (+)NCBIGRCr8
mRatBN7.21117,064,428 - 117,388,217 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1117,064,496 - 117,386,480 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01124,311,873 - 124,655,437 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1124,625,985 - 124,653,820 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01125,428,504 - 125,767,785 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41118,142,100 - 118,247,638 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1109,322,110 - 109,647,375 (+)NCBICelera
Cytogenetic Map1q22NCBI
Otud7a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541630,244,875 - 30,427,829 (-)NCBIChiLan1.0ChiLan1.0
OTUD7A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21620,288,790 - 20,677,159 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11525,006,920 - 25,401,235 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0159,974,737 - 10,360,991 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11529,014,295 - 29,217,332 (-)NCBIpanpan1.1PanPan1.1panPan2
OTUD7A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1337,348,167 - 37,548,357 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl337,348,170 - 37,548,885 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha339,829,134 - 40,221,120 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0337,535,390 - 37,922,120 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl337,535,447 - 37,921,786 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1337,068,759 - 37,455,071 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0337,323,919 - 37,708,706 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0337,531,469 - 37,918,419 (+)NCBIUU_Cfam_GSD_1.0
Otud7a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640145,895,615 - 146,220,872 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936483302,953 - 430,825 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936483113,611 - 432,439 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OTUD7A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1143,280,174 - 143,419,237 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11143,109,177 - 143,426,305 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21159,252,983 - 159,368,473 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Otud7a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247681,348,377 - 1,482,158 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247681,326,417 - 1,482,474 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in OTUD7A
11664 total Variants






RefSeq Acc Id: XM_008017183   ⟹   XP_008015374
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12650,842,957 - 51,213,515 (+)NCBI
Vero_WHO_p1.0NW_02366604889,610,838 - 89,983,865 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008017185   ⟹   XP_008015376
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12650,842,957 - 51,213,515 (+)NCBI
Vero_WHO_p1.0NW_02366604889,610,838 - 89,983,865 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008017189   ⟹   XP_008015380
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12650,842,958 - 51,213,515 (+)NCBI
Vero_WHO_p1.0NW_02366604889,610,045 - 89,983,853 (-)NCBI
Sequence:
Protein RefSeqs XP_008015374 (Get FASTA)   NCBI Sequence Viewer  
  XP_008015376 (Get FASTA)   NCBI Sequence Viewer  
  XP_008015380 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_008015376   ⟸   XM_008017185
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008015374   ⟸   XM_008017183
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008015380   ⟸   XM_008017189
- Peptide Label: isoform X2



Database
Acc Id
Source(s)
NCBI Gene OTUD7A ENTREZGENE