TRAF5 (TNF receptor associated factor 5) - Rat Genome Database

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Gene: TRAF5 (TNF receptor associated factor 5) Chlorocebus sabaeus
Analyze
Symbol: TRAF5
Name: TNF receptor associated factor 5
RGD ID: 18386991
Description: ENCODES a protein that exhibits enzyme binding (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN positive regulation of cell population proliferation (ortholog); signal transduction (ortholog); PARTICIPATES IN tumor necrosis factor mediated signaling pathway; ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); parathyroid carcinoma (ortholog); FOUND IN CD40 receptor complex (inferred); centrosome (inferred); cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: TNF receptor-associated factor 5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12518,124,720 - 18,173,601 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2518,126,973 - 18,152,172 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605518,654,929 - 18,705,636 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TRAF5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12518,124,720 - 18,173,601 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2518,126,973 - 18,152,172 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605518,654,929 - 18,705,636 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TRAF5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381211,326,635 - 211,374,946 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1211,326,615 - 211,374,946 (+)EnsemblGRCh38hg38GRCh38
GRCh371211,499,977 - 211,548,288 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361209,566,580 - 209,614,911 (+)NCBINCBI36Build 36hg18NCBI36
Celera1184,726,625 - 184,774,964 (+)NCBICelera
Cytogenetic Map1q32.3NCBI
HuRef1182,176,907 - 182,225,238 (+)NCBIHuRef
CHM1_11212,772,378 - 212,820,715 (+)NCBICHM1_1
T2T-CHM13v2.01210,572,246 - 210,620,555 (+)NCBIT2T-CHM13v2.0
Traf5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391191,729,164 - 191,776,899 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1191,729,166 - 191,776,868 (-)EnsemblGRCm39 Ensembl
GRCm381191,997,203 - 192,092,599 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1191,997,205 - 192,092,559 (-)EnsemblGRCm38mm10GRCm38
MGSCv371193,878,227 - 193,916,445 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv371193,821,088 - 193,823,851 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361193,755,802 - 193,793,206 (-)NCBIMGSCv36mm8
Celera1198,938,548 - 198,985,488 (-)NCBICelera
Cytogenetic Map1H6NCBI
cM Map197.11NCBI
Traf5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813106,100,921 - 106,149,724 (-)NCBIGRCr8
mRatBN7.213103,569,944 - 103,618,747 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13103,572,314 - 103,618,709 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13106,092,244 - 106,138,662 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013107,476,080 - 107,522,495 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013104,691,081 - 104,737,497 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013110,758,556 - 110,801,871 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13110,758,761 - 110,784,209 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013115,317,216 - 115,360,873 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera13103,011,066 - 103,057,720 (-)NCBICelera
Cytogenetic Map13q27NCBI
Traf5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955489949,890 - 995,162 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955489935,601 - 995,162 (-)NCBIChiLan1.0ChiLan1.0
TRAF5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2138,032,824 - 38,081,986 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1137,997,851 - 38,056,535 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01186,889,615 - 186,938,416 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11191,754,064 - 191,802,081 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1191,754,652 - 191,802,075 (+)Ensemblpanpan1.1panPan2
TRAF5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.179,812,019 - 9,831,955 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl79,812,132 - 9,831,955 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha79,387,019 - 9,406,432 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.079,487,603 - 9,536,016 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl79,487,589 - 9,535,453 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.179,437,996 - 9,457,395 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.079,539,555 - 9,559,154 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.079,664,230 - 9,683,648 (+)NCBIUU_Cfam_GSD_1.0
Traf5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934464,688,642 - 64,731,605 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365571,928,822 - 1,971,896 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365571,930,791 - 1,971,853 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRAF5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9131,775,470 - 131,822,529 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19131,772,810 - 131,822,555 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29144,808,707 - 144,828,506 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Traf5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624807878,665 - 898,558 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624807878,275 - 921,683 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 21 15 34
Low 15 5 26
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000013406   ⟹   ENSCSAP00000011407
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2518,126,973 - 18,152,172 (-)Ensembl
RefSeq Acc Id: XM_007988529   ⟹   XP_007986720
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12518,124,802 - 18,173,186 (-)NCBI
Vero_WHO_p1.0NW_02366605518,654,929 - 18,705,386 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007988530   ⟹   XP_007986721
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12518,124,802 - 18,153,690 (-)NCBI
Vero_WHO_p1.0NW_02366605518,654,929 - 18,686,862 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007988531   ⟹   XP_007986722
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12518,124,802 - 18,153,690 (-)NCBI
Vero_WHO_p1.0NW_02366605518,654,929 - 18,686,862 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007988532   ⟹   XP_007986723
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12518,124,720 - 18,173,189 (-)NCBI
Vero_WHO_p1.0NW_02366605518,654,929 - 18,705,538 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007988533   ⟹   XP_007986724
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12518,124,720 - 18,173,601 (-)NCBI
Vero_WHO_p1.0NW_02366605518,654,929 - 18,705,636 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007986720 (Get FASTA)   NCBI Sequence Viewer  
  XP_007986721 (Get FASTA)   NCBI Sequence Viewer  
  XP_007986722 (Get FASTA)   NCBI Sequence Viewer  
  XP_007986723 (Get FASTA)   NCBI Sequence Viewer  
  XP_007986724 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000011407.1
Reference Protein Sequences
RefSeq Acc Id: XP_007986724   ⟸   XM_007988533
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007986723   ⟸   XM_007988532
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007986720   ⟸   XM_007988529
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RS18 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007986721   ⟸   XM_007988530
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RS18 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007986722   ⟸   XM_007988531
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCSAP00000011407   ⟸   ENSCSAT00000013406


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000015311 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000013406.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro MATH/TRAF_dom UniProtKB/TrEMBL
  TNF_rcpt-assoc_TRAF_met UniProtKB/TrEMBL
  TRAF-like UniProtKB/TrEMBL
  TRAF5 UniProtKB/TrEMBL
  TRAF_MEP1_MATH_dom UniProtKB/TrEMBL
  Znf_C3HC4_RING-type UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
  Znf_TRAF UniProtKB/TrEMBL
KEGG Report csab:103230138 UniProtKB/TrEMBL
NCBI Gene TRAF5 ENTREZGENE
PANTHER PTHR10131 UniProtKB/TrEMBL
  PTHR10131:SF83 UniProtKB/TrEMBL
Pfam TRAF-mep_MATH UniProtKB/TrEMBL
  zf-C3HC4 UniProtKB/TrEMBL
  zf-TRAF UniProtKB/TrEMBL
PIRSF TRAF UniProtKB/TrEMBL
PROSITE MATH UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
  ZF_TRAF UniProtKB/TrEMBL
SMART MATH UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  TRAF domain-like UniProtKB/TrEMBL
UniProt A0A0D9RS18 ENTREZGENE, UniProtKB/TrEMBL