NEU1 (neuraminidase 1) - Rat Genome Database

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Gene: NEU1 (neuraminidase 1) Chlorocebus sabaeus
Analyze
Symbol: NEU1
Name: neuraminidase 1
RGD ID: 18380172
Description: ENCODES a protein that exhibits exo-alpha-sialidase activity (ortholog); INVOLVED IN positive regulation of neuron projection development (ortholog); regulation of myoblast proliferation (ortholog); ASSOCIATED WITH genetic disease (ortholog); glycoproteinosis (ortholog); Hydrops Fetalis (ortholog); FOUND IN cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sialidase-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11740,158,530 - 40,162,254 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1740,158,679 - 40,161,723 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604431,773,648 - 31,777,370 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
NEU1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11740,158,530 - 40,162,254 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1740,158,679 - 40,161,723 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604431,773,648 - 31,777,370 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
NEU1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38631,857,659 - 31,862,821 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl631,857,063 - 31,862,905 (-)EnsemblGRCh38hg38GRCh38
GRCh37631,825,436 - 31,830,598 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,934,931 - 31,938,662 (-)NCBINCBI36Build 36hg18NCBI36
Build 34631,934,931 - 31,938,662NCBI
Celera633,425,415 - 33,429,295 (-)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef631,612,642 - 31,616,522 (-)NCBIHuRef
CHM1_1631,828,970 - 31,832,850 (-)NCBICHM1_1
T2T-CHM13v2.0631,710,899 - 31,716,061 (-)NCBIT2T-CHM13v2.0
Neu1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,150,229 - 35,156,273 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1735,150,229 - 35,154,929 (+)EnsemblGRCm39 Ensembl
GRCm381734,931,253 - 34,937,297 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,931,253 - 34,935,953 (+)EnsemblGRCm38mm10GRCm38
MGSCv371735,068,198 - 35,074,242 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,539,435 - 34,543,377 (+)NCBIMGSCv36mm8
Celera1738,027,486 - 38,033,530 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.48NCBI
Neu1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8203,902,120 - 3,906,383 (-)NCBIGRCr8
mRatBN7.2203,897,480 - 3,901,745 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl203,897,480 - 3,901,745 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,597,480 - 4,601,727 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0203,959,222 - 3,963,469 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,496,415 - 4,500,659 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0204,610,995 - 4,615,258 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,610,995 - 4,615,247 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,690,982 - 6,695,245 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,999,317 - 4,003,800 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1203,999,977 - 4,003,886 (-)NCBI
Celera204,127,729 - 4,131,992 (+)NCBICelera
Cytogenetic Map20p12NCBI
Neu1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955437378,708 - 383,085 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955437378,708 - 383,076 (-)NCBIChiLan1.0ChiLan1.0
NEU1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,338,259 - 46,342,058 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1642,299,753 - 42,303,551 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,522,392 - 31,526,097 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,409,217 - 32,412,971 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,409,217 - 32,412,971 (-)Ensemblpanpan1.1panPan2
NEU1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,323,659 - 1,327,989 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,323,877 - 1,328,520 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,458,231 - 1,463,184 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,465,128 - 1,470,088 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,465,833 - 1,469,900 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,322,829 - 1,327,813 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,390,787 - 1,395,741 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,455,970 - 1,460,945 (-)NCBIUU_Cfam_GSD_1.0
Neu1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494635,874,214 - 35,878,035 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367271,683,204 - 1,688,883 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367271,683,283 - 1,687,130 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NEU1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl723,947,061 - 23,958,666 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1723,953,721 - 23,958,659 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2727,853,642 - 27,858,581 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Neu1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475424,382,467 - 24,387,874 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475424,382,509 - 24,386,410 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000006875   ⟹   ENSCSAP00000005070
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1740,158,679 - 40,161,723 (+)Ensembl
RefSeq Acc Id: XM_007973077   ⟹   XP_007971268
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11740,158,530 - 40,162,254 (+)NCBI
Vero_WHO_p1.0NW_02366604431,773,648 - 31,777,370 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007973078   ⟹   XP_007971269
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11740,158,600 - 40,162,254 (+)NCBI
Vero_WHO_p1.0NW_02366604431,773,648 - 31,777,344 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007971268 (Get FASTA)   NCBI Sequence Viewer  
  XP_007971269 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000005070
  ENSCSAP00000005070.1
RefSeq Acc Id: XP_007971268   ⟸   XM_007973077
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R8Y1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007971269   ⟸   XM_007973078
- Peptide Label: isoform X2
Ensembl Acc Id: ENSCSAP00000005070   ⟸   ENSCSAT00000006875


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000008815 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000006875.1 UniProtKB/TrEMBL
Gene3D-CATH 2.120.10.10 UniProtKB/TrEMBL
InterPro Sialidase UniProtKB/TrEMBL
  Sialidase_fam UniProtKB/TrEMBL
  Sialidase_sf UniProtKB/TrEMBL
KEGG Report csab:103221742 UniProtKB/TrEMBL
NCBI Gene NEU1 ENTREZGENE
PANTHER PTHR10628 UniProtKB/TrEMBL
  SIALIDASE-1 UniProtKB/TrEMBL
Pfam BNR_2 UniProtKB/TrEMBL
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
Superfamily-SCOP SSF50939 UniProtKB/TrEMBL
UniProt A0A0D9R8Y1 ENTREZGENE, UniProtKB/TrEMBL