NEU1 (neuraminidase 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: NEU1 (neuraminidase 1) Sus scrofa
Analyze
Symbol: NEU1
Name: neuraminidase 1
RGD ID: 14218417
Description: ENCODES a protein that exhibits exo-alpha-sialidase activity (ortholog); INVOLVED IN oligosaccharide catabolic process (ortholog); positive regulation of neuron projection development (ortholog); regulation of myoblast proliferation (ortholog); ASSOCIATED WITH genetic disease (ortholog); glycoproteinosis (ortholog); Hydrops Fetalis (ortholog); FOUND IN cell surface (ortholog); lysosome (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: acetylneuraminyl hydrolase; lysosomal sialidase; N-acetyl-alpha-neuraminidase 1; sialidase 1 (lysosomal sialidase); sialidase-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl723,947,061 - 23,958,666 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1723,953,721 - 23,958,659 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2727,853,642 - 27,858,581 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
NEU1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl723,947,061 - 23,958,666 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1723,953,721 - 23,958,659 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2727,853,642 - 27,858,581 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NEU1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38631,857,659 - 31,862,821 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl631,857,063 - 31,862,905 (-)EnsemblGRCh38hg38GRCh38
GRCh37631,825,436 - 31,830,598 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,934,931 - 31,938,662 (-)NCBINCBI36Build 36hg18NCBI36
Build 34631,934,931 - 31,938,662NCBI
Celera633,425,415 - 33,429,295 (-)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef631,612,642 - 31,616,522 (-)NCBIHuRef
CHM1_1631,828,970 - 31,832,850 (-)NCBICHM1_1
T2T-CHM13v2.0631,710,899 - 31,716,061 (-)NCBIT2T-CHM13v2.0
Neu1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,150,229 - 35,156,273 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1735,150,229 - 35,154,929 (+)EnsemblGRCm39 Ensembl
GRCm381734,931,253 - 34,937,297 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,931,253 - 34,935,953 (+)EnsemblGRCm38mm10GRCm38
MGSCv371735,068,198 - 35,074,242 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,539,435 - 34,543,377 (+)NCBIMGSCv36mm8
Celera1738,027,486 - 38,033,530 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.48NCBI
Neu1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8203,902,120 - 3,906,383 (-)NCBIGRCr8
mRatBN7.2203,897,480 - 3,901,745 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl203,897,480 - 3,901,745 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,597,480 - 4,601,727 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0203,959,222 - 3,963,469 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,496,415 - 4,500,659 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0204,610,995 - 4,615,258 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,610,995 - 4,615,247 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,690,982 - 6,695,245 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,999,317 - 4,003,800 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1203,999,977 - 4,003,886 (-)NCBI
Celera204,127,729 - 4,131,992 (+)NCBICelera
Cytogenetic Map20p12NCBI
Neu1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955437378,708 - 383,085 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955437378,708 - 383,076 (-)NCBIChiLan1.0ChiLan1.0
NEU1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,338,259 - 46,342,058 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1642,299,753 - 42,303,551 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,522,392 - 31,526,097 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,409,217 - 32,412,971 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,409,217 - 32,412,971 (-)Ensemblpanpan1.1panPan2
NEU1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,323,659 - 1,327,989 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,323,877 - 1,328,520 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,458,231 - 1,463,184 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,465,128 - 1,470,088 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,465,833 - 1,469,900 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,322,829 - 1,327,813 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,390,787 - 1,395,741 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,455,970 - 1,460,945 (-)NCBIUU_Cfam_GSD_1.0
Neu1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494635,874,214 - 35,878,035 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367271,683,204 - 1,688,883 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367271,683,283 - 1,687,130 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NEU1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11740,158,530 - 40,162,254 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1740,158,679 - 40,161,723 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604431,773,648 - 31,777,370 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Neu1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475424,382,467 - 24,387,874 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475424,382,509 - 24,386,410 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NEU1
111 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000001555   ⟹   ENSSSCP00000001513
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl723,952,867 - 23,958,666 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000090675   ⟹   ENSSSCP00000074519
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl723,947,061 - 23,958,638 (-)Ensembl
RefSeq Acc Id: NM_001101822   ⟹   NP_001095292
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1723,953,721 - 23,958,659 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001095292 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein A5PF10 (Get FASTA)   NCBI Sequence Viewer  
  ABX82833 (Get FASTA)   NCBI Sequence Viewer  
  CAN87707 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000001513.3
  ENSSSCP00000074519
  ENSSSCP00000074519.1
  ENSSSCP00015044874.1
  ENSSSCP00070039491.1
RefSeq Acc Id: NP_001095292   ⟸   NM_001101822
- Peptide Label: precursor
- UniProtKB: A5PF10 (UniProtKB/Swiss-Prot),   B9TSS6 (UniProtKB/TrEMBL),   A0A8D0Q7F3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000001513   ⟸   ENSSSCT00000001555
Ensembl Acc Id: ENSSSCP00000074519   ⟸   ENSSSCT00000090675
Protein Domains
Sialidase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000001418 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015078693 UniProtKB/TrEMBL
  ENSSSCG00070023485 UniProtKB/Swiss-Prot
Ensembl Transcript ENSSSCT00000001555.5 UniProtKB/TrEMBL
  ENSSSCT00000090675 ENTREZGENE
  ENSSSCT00000090675.1 UniProtKB/TrEMBL
  ENSSSCT00015106589.1 UniProtKB/TrEMBL
  ENSSSCT00070046815.1 UniProtKB/Swiss-Prot
Gene3D-CATH 2.120.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Sialidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sialidase_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sialidase_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:100124381 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene NEU1 ENTREZGENE
PANTHER PTHR10628 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SIALIDASE-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BNR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50939 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A5G2RH94_PIG UniProtKB/TrEMBL
  A0A8D0Q7F3 ENTREZGENE, UniProtKB/TrEMBL
  A5PF10 ENTREZGENE
  B9TSS6 ENTREZGENE, UniProtKB/TrEMBL
  F1RQX3_PIG UniProtKB/TrEMBL
  NEUR1_PIG UniProtKB/Swiss-Prot
VGNC ID VGNC:90692 ENTREZGENE