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Gene: SUMO2 (small ubiquitin like modifier 2) Chlorocebus sabaeus

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Symbol:

SUMO2

Name:

small ubiquitin like modifier 2

RGD ID:

18337539

Description:

ENCODES a protein that exhibits nuclear retinoid X receptor binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regulation of protein sumoylation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); FOUND IN GABA-ergic synapse (ortholog); glutamatergic synapse (ortholog); hippocampal mossy fiber to CA3 synapse (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

small ubiquitin-related modifier 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	46,479,399 - 46,495,591 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	46,479,406 - 46,496,114 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	17,253,281 - 17,269,592 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of DNA-templated transcription (ISO)

positive regulation of proteasomal ubiquitin-dependent protein catabolic process (IEA)

positive regulation of protein sumoylation (ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

protein localization (ISO)

protein sumoylation (IEA,ISO)

Cellular Component

cytoplasm (IEA)

GABA-ergic synapse (IEA,ISO)

glutamatergic synapse (IEA,ISO)

hippocampal mossy fiber to CA3 synapse (IEA,ISO)

nucleus (IEA)

PML body (IEA)

postsynapse (IEA,ISO)

postsynaptic cytosol (IEA,ISO)

presynapse (IEA,ISO)

presynaptic cytosol (IEA,ISO)

Molecular Function

nuclear retinoid X receptor binding (ISO)

protein binding (ISO)

SUMO transferase activity (IEA)

ubiquitin protein ligase binding (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

SUMO2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	46,479,399 - 46,495,591 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	46,479,406 - 46,496,114 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	17,253,281 - 17,269,592 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

SUMO2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	75,165,586 - 75,182,959 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	75,165,586 - 75,182,959 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	73,161,681 - 73,179,054 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	70,675,420 - 70,690,693 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	70,675,419 - 70,690,693	NCBI
Celera	17	69,756,196 - 69,771,477 (-)	NCBI		Celera
Cytogenetic Map	17	q25.1	NCBI
HuRef	17	68,573,023 - 68,588,319 (-)	NCBI		HuRef
CHM1_1	17	73,228,330 - 73,243,802 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	76,057,065 - 76,074,452 (-)	NCBI		T2T-CHM13v2.0

Sumo2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	115,413,935 - 115,427,056 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	115,413,928 - 115,427,102 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	115,523,109 - 115,536,230 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	115,523,102 - 115,536,276 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	115,384,423 - 115,397,544 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	116,412,880 - 116,426,015 (-)	NCBI		MGSCv36	mm8
MGSCv36	11	115,339,199 - 115,352,320 (-)	NCBI		MGSCv36	mm8
Celera	11	127,289,555 - 127,301,144 (-)	NCBI		Celera
Cytogenetic Map	11	E2	NCBI
cM Map	11	80.84	NCBI

Sumo2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	101,270,899 - 101,283,458 (-)	NCBI		GRCr8
mRatBN7.2	10	100,771,941 - 100,784,503 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	100,686,797 - 100,784,513 (-)	Ensembl		mRatBN7.2 Ensembl
mRatBN7.2 Ensembl	5	15,099,419 - 15,099,706 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	105,831,894 - 105,844,470 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	105,294,964 - 105,307,540 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	100,692,910 - 100,705,469 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	104,085,401 - 104,097,983 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	104,086,002 - 104,097,812 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	104,184,388 - 104,195,497 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	105,608,097 - 105,620,455 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	10	99,346,621 - 99,359,172 (-)	NCBI		Celera
Cytogenetic Map	10	q32.1	NCBI

Sumo2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955553	2,045,415 - 2,065,863 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955553	2,045,277 - 2,066,023 (-)	NCBI	ChiLan1.0	ChiLan1.0

SUMO2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	91,207,894 - 91,222,668 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	96,030,950 - 96,045,638 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	69,115,433 - 69,130,065 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	74,676,897 - 74,683,990 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

SUMO2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	5,298,315 - 5,311,184 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	5,298,340 - 5,311,184 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	5,977,248 - 5,990,106 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	5,968,618 - 5,981,517 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	5,968,617 - 5,981,522 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	6,007,031 - 6,019,893 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	6,117,312 - 6,130,163 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	6,177,319 - 6,190,161 (+)	NCBI		UU_Cfam_GSD_1.0

Sumo2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	5,925,294 - 5,942,343 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936594	469,616 - 484,375 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SUMO2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	6,116,606 - 6,130,350 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	6,116,694 - 6,130,089 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	6,079,142 - 6,092,538 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Sumo2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624801	4,998,271 - 5,009,492 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in SUMO2
266 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008011783	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_037993254	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000002740 ⟹ ENSCSAP00000001037

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	16	46,479,406 - 46,496,114 (+)	Ensembl

RefSeq Acc Id:

XM_008011783 ⟹ XP_008009974

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	16	46,479,399 - 46,495,591 (+)	NCBI
Vero_WHO_p1.0	NW_023666077	17,253,281 - 17,269,592 (+)	NCBI

Sequence:

show sequence

CGCAGGGTGGGGGGAGGGAGCGCACGACGTGCGCGCACCCTCTCCCTCGTCCACCGCTGCCGCC
TCCTTCTTCTGCCGCTCCTGGTGCTGCTTGTGTGCTCGTTTGGTGCGGACCTGGTACCTCTTTT
GTGAAGCGGCAGCTGAGGAGACTCCGGCGCTCGCCATGGCCGACGAAAAGCCCAAGGAAGGAGT
CAAGACTGAGAACAACGATCATATTAATTTGAAGGTGGCGGGGCAGGATGGTTCTGTGGTGCAG
TTTAAGATTAAGAGGCATACACCACTTAGTAAACTAATGAAAGCCTATTGTGAACGACAGGGAT
TGTCAATGAGGCAGATCAGATTCCGATTCGACGGGCAACCAATCAATGAAACAGACACACCTGC
ACAGTTGGAAATGGAGGATGAAGATACAATTGATGTGTTCCAACAGCAGACGGGAGGTGTCTAC
TGAAAAGGGAACCTGCTTCTTTACTCCAGAACTCTGTTCTTTAAAGACCAAGATTACATTCTCA
ATTAGAAAACTGCAATTTGGTTCCACCACATCCTGACTACTACCGTATAGTTTTCTCTATTCTT
TCATTTCCCCCTTCCCCATTCCTTTATTGTACATAAAGTAACTGGTATATGTGCACAAGCATAT
TGCATTTTTTTTTTTTTTTAACTAAACAGCCAATGGTATGTTTTAATTGACATCAAGTGGAGAC
GGGATGGGGAAAAATACTGATTCTGTGAAAATACCCCCTTTCTCCATTAGTGGCATGCTCATTC
AGCTCTTATCATTAAGATTCCAGTAAGTTATTTTGCTCTCACTGTTTTAACAAAAACACACAAC
ATAAAAATCCTTGCATACCTTGTTCAATTGGAGAATTTTAATGTTTTTCATTTATCATTGTAAA
ACCAAGGACAATTTTATAACTTTTTTGTACGTAGCTGTTACATGTAGGGCAATCTGTCTTTAAG
TAGGGATAAATTACTCTAAAACAAAAAAGAATCTTAGATAGTTTTCCCTTCAAGTCAAGCGTCT
TGTTGTTTAAATAAACTTCTTGTTTAAAATGA

hide sequence

RefSeq Acc Id:

XM_037993254 ⟹ XP_037849182

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666077	17,253,294 - 17,269,592 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_008009974	(Get FASTA)	NCBI Sequence Viewer
	XP_037849182	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000001037
	ENSCSAP00000001037.1
	ENSCSAP00000003778.1

RefSeq Acc Id:	XP_008009974 ⟸ XM_008011783
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9QXE8 (UniProtKB/TrEMBL), A0A0D9R589 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000001037 ⟸ ENSCSAT00000002740

RefSeq Acc Id:	XP_037849182 ⟸ XM_037993254
- Peptide Label:	isoform X2

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000004710	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSCSAG00000007518	UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000002740.1	UniProtKB/TrEMBL
	ENSCSAT00000005561.1	UniProtKB/TrEMBL
InterPro	Rad60/SUMO-like_dom	UniProtKB/TrEMBL
	Ubiquitin-like_dom	UniProtKB/TrEMBL
	Ubiquitin-like_domsf	UniProtKB/TrEMBL
KEGG Report	csab:103243054	UniProtKB/TrEMBL
NCBI Gene	SUMO2	ENTREZGENE
PANTHER	SMALL UBIQUITIN-RELATED MODIFIER	UniProtKB/TrEMBL
	SMALL UBIQUITIN-RELATED MODIFIER 3	UniProtKB/TrEMBL
	SMALL UBIQUITIN-RELATED MODIFIER 3-RELATED	UniProtKB/TrEMBL
Pfam	Rad60-SLD	UniProtKB/TrEMBL
PROSITE	UBIQUITIN_2	UniProtKB/TrEMBL
SMART	UBQ	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54236	UniProtKB/TrEMBL
UniProt	A0A0D9QXE8	ENTREZGENE, UniProtKB/TrEMBL
	A0A0D9R589	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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