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Gene: EIF3CL (eukaryotic translation initiation factor 3 subunit C like) Homo sapiens

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Symbol:

EIF3CL

Name:

eukaryotic translation initiation factor 3 subunit C like

RGD ID:

1626547

HGNC Page

HGNC:26347

Description:

Enables ribosome binding activity. Contributes to translation initiation factor activity. Involved in positive regulation of translation and translational initiation. Part of eukaryotic translation initiation factor 3 complex.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

eIF3 p110; eIF3c; eukaryotic translation initiation factor 3 subunit 8; eukaryotic translation initiation factor 3 subunit C; eukaryotic translation initiation factor 3 subunit C-like; eukaryotic translation initiation factor 3 subunit C-like protein; eukaryotic translation initiation factor 3, subunit 8, 110kDa-like; eukaryotic translation initiation factor 3, subunit C-like; LOC112268171; uncharacterized LOC112268171

RGD Orthologs

Bonobo

Dog

Pig

Alliance Orthologs

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	28,379,581 - 28,426,418 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	28,379,579 - 28,403,841 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	28,390,902 - 28,415,206 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	28,298,401 - 28,322,663 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	16	28,059,153 - 28,083,429 (-)	NCBI		Celera
Cytogenetic Map	16	p12.1	NCBI
HuRef	16	26,450,046 - 26,474,307 (-)	NCBI		HuRef
CHM1_1	16	29,404,042 - 29,426,909 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	28,659,992 - 28,707,115 (-)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
EIF3CL	Human	neuronal ceroid lipofuscinosis		IAGP	(Homo sapiens)	8554872	ClinVar Annotator: match by term: Neuronal ceroid lipofuscinosis	ClinVar	PMID:28492532 more ...
EIF3CL	Human	schizophrenia		IAGP	(Homo sapiens)	8554872	ClinVar Annotator: match by term: Schizophrenia	ClinVar	PMID:21681106 and PMID:30208311

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
EIF3CL	Human	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of EIF3CL mRNA	CTD	PMID:29704546
EIF3CL	Human	2,6-dimethoxyphenol	multiple interactions	EXP		6480464	[Furaldehyde co-treated with pyrogallol 1 more ...	CTD	PMID:38598786
EIF3CL	Human	aflatoxin M1	increases expression	EXP		6480464	Aflatoxin M1 results in increased expression of EIF3CL mRNA	CTD	PMID:30928695
EIF3CL	Human	benzatropine	multiple interactions	EXP		6480464	[Cuprizone co-treated with Benztropine] results in decreased expression of EIF3CL protein	CTD	PMID:34122009
EIF3CL	Human	bis(2-ethylhexyl) phthalate	increases expression	EXP		6480464	Diethylhexyl Phthalate results in increased expression of EIF3CL mRNA	CTD	PMID:28412506 and PMID:35892601
EIF3CL	Human	bis(2-ethylhexyl) phthalate	multiple interactions	EXP		6480464	[Colforsin co-treated with Diethylhexyl Phthalate] affects the expression of EIF3CL mRNA	CTD	PMID:35892601
EIF3CL	Human	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of EIF3CL mRNA	CTD	PMID:37244401
EIF3CL	Human	colforsin daropate hydrochloride	multiple interactions	EXP		6480464	[Colforsin co-treated with Diethylhexyl Phthalate] affects the expression of EIF3CL mRNA	CTD	PMID:35892601
EIF3CL	Human	Cuprizon	multiple interactions	EXP		6480464	[Cuprizone co-treated with Benztropine] results in decreased expression of EIF3CL protein	CTD	PMID:34122009
EIF3CL	Human	cyclosporin A	increases methylation	EXP		6480464	Cyclosporine results in increased methylation of EIF3CL promoter	CTD	PMID:27989131
EIF3CL	Human	doxorubicin	increases expression	EXP		6480464	Doxorubicin results in increased expression of EIF3CL mRNA	CTD	PMID:29803840
EIF3CL	Human	furfural	multiple interactions	EXP		6480464	[Furaldehyde co-treated with pyrogallol 1 more ...	CTD	PMID:38598786
EIF3CL	Human	sodium chloride	multiple interactions	EXP		6480464	[Sodium Chloride co-treated with Furaldehyde] results in decreased expression of EIF3CL protein more ...	CTD	PMID:38598786
EIF3CL	Human	Tetrachlorobisphenol A	increases expression	EXP		6480464	tetrachlorodian results in increased expression of EIF3CL mRNA	CTD	PMID:31326446
EIF3CL	Human	Theaflavin 3,3'-digallate	affects expression	EXP		6480464	theaflavin-3 and 3'-digallate affects the expression of EIF3CL mRNA	CTD	PMID:34925699
EIF3CL	Human	valproic acid	decreases expression	EXP		6480464	Valproic Acid results in decreased expression of EIF3CL mRNA	CTD	PMID:19101580

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
EIF3CL	Human	cytoplasmic translational initiation	involved_in	IEA	UniRule:UR000106250	150520179		UniProt	GO_REF:0000104
EIF3CL	Human	formation of cytoplasmic translation initiation complex	involved_in	NAS		150520179	PMID:16920360	ComplexPortal	PMID:16920360
EIF3CL	Human	formation of cytoplasmic translation initiation complex	involved_in	IEA	UniRule:UR000106250	150520179		UniProt	GO_REF:0000104
EIF3CL	Human	positive regulation of translation	involved_in	IPI	UniProtKB:O15371 more ...	150520179	PMID:24092755	ParkinsonsUK-UCL	PMID:24092755
EIF3CL	Human	translation	involved_in	IEA	UniProtKB-KW:KW-0648	150520179		UniProt	GO_REF:0000043
EIF3CL	Human	translational initiation	involved_in	IC	GO:0005852	150520179	PMID:17322308 and PMID:18599441	UniProt	PMID:17322308 and PMID:18599441
EIF3CL	Human	translational initiation	involved_in	IBA	MGI:1926966 more ...	150520179		GO_Central	GO_REF:0000033
EIF3CL	Human	translational initiation	involved_in	IEA	UniProtKB-KW:KW-0396	150520179		UniProt	GO_REF:0000043
EIF3CL	Human	translational initiation	involved_in	IEA	InterPro:IPR008905 and InterPro:IPR027516	150520179		InterPro	GO_REF:0000002
EIF3CL	Human	translational initiation	involved_in	IDA		150520179	PMID:17581632	UniProt	PMID:17581632

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
EIF3CL	Human	cytoplasm	located_in	IEA	UniProtKB-KW:KW-0963	150520179		UniProt	GO_REF:0000043
EIF3CL	Human	cytoplasm	located_in	IEA	UniProtKB-SubCell:SL-0086	150520179		UniProt	GO_REF:0000044
EIF3CL	Human	cytoplasm	located_in	IEA	UniRule:UR000106250	150520179		UniProt	GO_REF:0000104
EIF3CL	Human	cytosol	located_in	TAS		150520179		Reactome	Reactome:R-HSA-156808 more ...
EIF3CL	Human	eukaryotic 43S preinitiation complex	part_of	IEA	UniRule:UR000106250	150520179		UniProt	GO_REF:0000104
EIF3CL	Human	eukaryotic 48S preinitiation complex	part_of	IEA	UniRule:UR000106250	150520179		UniProt	GO_REF:0000104
EIF3CL	Human	eukaryotic translation initiation factor 3 complex	part_of	IPI		150520179	PMID:17322308	ComplexPortal	PMID:17322308
EIF3CL	Human	eukaryotic translation initiation factor 3 complex	part_of	IBA	MGI:1926966 more ...	150520179		GO_Central	GO_REF:0000033
EIF3CL	Human	eukaryotic translation initiation factor 3 complex	part_of	IEA	UniRule:UR000106250	150520179		UniProt	GO_REF:0000104
EIF3CL	Human	eukaryotic translation initiation factor 3 complex	part_of	IEA	InterPro:IPR008905 and InterPro:IPR027516	150520179		InterPro	GO_REF:0000002
EIF3CL	Human	eukaryotic translation initiation factor 3 complex	part_of	IDA		150520179	PMID:17322308 more ...	UniProt	PMID:17322308 more ...
EIF3CL	Human	protein-containing complex	part_of	IEA	ARBA:ARBA00028902	150520179		UniProt	GO_REF:0000117

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
EIF3CL	Human	protein binding	enables	IPI	UniProtKB:O15371 more ...	150520179	PMID:24092755	ParkinsonsUK-UCL	PMID:24092755
EIF3CL	Human	protein binding	enables	IPI	UniProtKB:Q05086-2	150520179	PMID:29426014	IntAct	PMID:29426014
EIF3CL	Human	protein binding	enables	IPI	UniProtKB:P41567	150520179	PMID:29987188	UniProt	PMID:29987188
EIF3CL	Human	protein binding	enables	IPI	UniProtKB:Q9Q2G4	150520179	PMID:22190034	IntAct	PMID:22190034
EIF3CL	Human	protein binding	enables	IPI	UniProtKB:P60228 and UniProtKB:Q14152	150520179	PMID:18599441	IntAct	PMID:18599441
EIF3CL	Human	protein binding	enables	IPI	UniProtKB:O15372 and UniProtKB:P60228	150520179	PMID:28514442	IntAct	PMID:28514442
EIF3CL	Human	protein binding	enables	IPI	UniProtKB:Q9H8W4	150520179	PMID:32296183	IntAct	PMID:32296183
EIF3CL	Human	protein binding	enables	IPI	UniProtKB:P60228	150520179	PMID:10504338	IntAct	PMID:10504338
EIF3CL	Human	protein binding	enables	IPI	UniProtKB:O15372	150520179	PMID:30021884	IntAct	PMID:30021884
EIF3CL	Human	protein binding	enables	IPI	UniProtKB:P41567 more ...	150520179	PMID:23623729	IntAct	PMID:23623729
EIF3CL	Human	protein binding	enables	IPI	UniProtKB:O15372 more ...	150520179	PMID:33961781	IntAct	PMID:33961781
EIF3CL	Human	protein binding	enables	IPI	UniProtKB:O00571	150520179	PMID:18628297 and PMID:22323517	IntAct	PMID:18628297 and PMID:22323517
EIF3CL	Human	ribosome binding	enables	IDA		150520179	PMID:8995409	MGI	PMID:8995409
EIF3CL	Human	RNA binding	enables	HDA		150520179	PMID:22658674 and PMID:22681889	UniProt	PMID:22658674 and PMID:22681889
EIF3CL	Human	RNA binding	enables	IEA	InterPro:IPR027516	150520179		InterPro	GO_REF:0000002
EIF3CL	Human	translation initiation factor activity	contributes_to	IC	GO:0005852	150520179	PMID:17322308 and PMID:18599441	UniProt	PMID:17322308 and PMID:18599441
EIF3CL	Human	translation initiation factor activity	contributes_to	IBA	PANTHER:PTN000358559 and UniProtKB:Q99613	150520179		GO_Central	GO_REF:0000033
EIF3CL	Human	translation initiation factor activity	enables	IEA	InterPro:IPR008905 and InterPro:IPR027516	150520179		InterPro	GO_REF:0000002
EIF3CL	Human	translation initiation factor activity	enables	IEA	UniProtKB-KW:KW-0396	150520179		UniProt	GO_REF:0000043
EIF3CL	Human	translation initiation factor activity	enables	IEA	UniRule:UR000106250	150520179		UniProt	GO_REF:0000104
EIF3CL	Human	translation initiation factor activity	contributes_to	IDA		150520179	PMID:17581632 and PMID:25849773	UniProt	PMID:17581632 and PMID:25849773
EIF3CL	Human	translation initiation factor binding	enables	IEA	InterPro:IPR008905 and InterPro:IPR027516	150520179		InterPro	GO_REF:0000002
EIF3CL	Human	translation initiation factor binding	enables	IBA	PANTHER:PTN000358559 and SGD:S000004926	150520179		GO_Central	GO_REF:0000033

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
EIF3CL	Human	Schizophrenia		IAGP	(Homo sapiens)	8554872	ClinVar Annotator: match by term: Schizophrenia	ClinVar	PMID:21681106 and PMID:30208311
EIF3CL	Human	Schizophrenia		IAGP	(Homo sapiens)	8554872	ClinVar Annotator: match by term: Schizophrenia	ClinVar

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:8995409	PMID:10493829	PMID:10504338	PMID:12477932	PMID:14519125	PMID:14702039	PMID:15302935	PMID:15489334	PMID:15703437	PMID:16083285	PMID:16097034	PMID:16286006
PMID:16322461	PMID:16344560	PMID:16964243	PMID:17081983	PMID:17287340	PMID:17322308	PMID:17581632	PMID:18187866	PMID:18599441	PMID:18669648	PMID:20360068	PMID:21145461
PMID:21873635	PMID:22863883	PMID:23463506	PMID:25201988	PMID:25963833	PMID:26186194	PMID:26344197	PMID:27173435	PMID:28514442	PMID:28581483	PMID:29509190	PMID:30021884
PMID:30022168	PMID:30463901	PMID:30554943	PMID:30884312	PMID:30948266	PMID:31332168	PMID:31462741	PMID:31527668	PMID:31586073	PMID:31871319	PMID:31980649	PMID:32433965
PMID:32807901	PMID:33001583	PMID:33306668	PMID:33961781	PMID:34079125	PMID:34316702	PMID:34373451	PMID:34535262	PMID:34857952	PMID:35256949	PMID:35271311	PMID:35446349
PMID:35562734	PMID:35563538	PMID:35676659	PMID:35777956	PMID:36215168	PMID:36261009	PMID:36526897	PMID:36574265	PMID:36597993	PMID:36736316	PMID:37071682	PMID:37151849
PMID:37317656	PMID:37448957	PMID:37499664

EIF3CL
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	28,379,581 - 28,426,418 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	28,379,579 - 28,403,841 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	28,390,902 - 28,415,206 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	28,298,401 - 28,322,663 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	16	28,059,153 - 28,083,429 (-)	NCBI		Celera
Cytogenetic Map	16	p12.1	NCBI
HuRef	16	26,450,046 - 26,474,307 (-)	NCBI		HuRef
CHM1_1	16	29,404,042 - 29,426,909 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	28,659,992 - 28,707,115 (-)	NCBI		T2T-CHM13v2.0

EIF3CL
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	29,766,299 - 29,809,615 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	34,307,515 - 34,346,162 (-)	NCBI		NHGRI_mPanPan1

LOC479795
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	18,276,824 - 18,299,336 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	19,855,500 - 19,878,019 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	18,412,847 - 18,435,356 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	6	18,211,867 - 18,234,448 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	18,127,171 - 18,149,676 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	18,443,260 - 18,465,768 (+)	NCBI		UU_Cfam_GSD_1.0

LOC110260088
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	3	18,467,725 - 18,489,088 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

Variants in EIF3CL
7 total Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 16p12.2-11.2(chr16:21463739-29249579)x3	copy number gain	See cases [RCV000051829]	Chr16:21463739..29249579 [GRCh38] Chr16:21475060..29260900 [GRCh37] Chr16:21382561..29168401 [NCBI36] Chr16:16p12.2-11.2	pathogenic
GRCh38/hg38 16p12.2-11.2(chr16:21602183-29314373)x3	copy number gain	See cases [RCV000051842]	Chr16:21602183..29314373 [GRCh38] Chr16:21613504..29325694 [GRCh37] Chr16:21521005..29233195 [NCBI36] Chr16:16p12.2-11.2	pathogenic
GRCh38/hg38 16p12.2-11.2(chr16:23047969-30632245)x3	copy number gain	See cases [RCV000052401]	Chr16:23047969..30632245 [GRCh38] Chr16:23059290..30643566 [GRCh37] Chr16:22966791..30551067 [NCBI36] Chr16:16p12.2-11.2	pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28293803-29531653)x3	copy number gain	See cases [RCV000053118]	Chr16:28293803..29531653 [GRCh38] Chr16:28305124..29542974 [GRCh37] Chr16:28212625..29450475 [NCBI36] Chr16:16p12.1-11.2	uncertain significance
GRCh38/hg38 16p12.1-11.2(chr16:28366111-30183432)x3	copy number gain	See cases [RCV000054346]	Chr16:28366111..30183432 [GRCh38] Chr16:28377432..30194753 [GRCh37] Chr16:28284933..30102254 [NCBI36] Chr16:16p12.1-11.2	pathogenic\|uncertain significance
GRCh38/hg38 16p12.1-11.2(chr16:28061312-28584375)x3	copy number gain	See cases [RCV000053862]	Chr16:28061312..28584375 [GRCh38] Chr16:28072633..28595696 [GRCh37] Chr16:27980134..28503197 [NCBI36] Chr16:16p12.1-11.2	uncertain significance
NM_001199142.1(EIF3C):c.911T>G (p.Val304Gly)	single nucleotide variant	Malignant melanoma [RCV000063017]	Chr16:28723298 [GRCh38] Chr16:28734619 [GRCh37] Chr16:28642120 [NCBI36] Chr16:16p11.2	not provided
GRCh38/hg38 16p13.3-11.2(chr16:4644892-29170820)x3	copy number gain	See cases [RCV000133809]	Chr16:4644892..29170820 [GRCh38] Chr16:4694893..29182141 [GRCh37] Chr16:4634894..29089642 [NCBI36] Chr16:16p13.3-11.2	pathogenic
GRCh38/hg38 16p12.2-11.2(chr16:22634385-29227323)x3	copy number gain	See cases [RCV000135594]	Chr16:22634385..29227323 [GRCh38] Chr16:22645706..29238644 [GRCh37] Chr16:22553207..29146145 [NCBI36] Chr16:16p12.2-11.2	likely pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28392832-30186020)x1	copy number loss	See cases [RCV000137580]	Chr16:28392832..30186020 [GRCh38] Chr16:28404153..30197341 [GRCh37] Chr16:28311654..30104842 [NCBI36] Chr16:16p12.1-11.2	pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28392832-29342070)x1	copy number loss	See cases [RCV000137949]	Chr16:28392832..29342070 [GRCh38] Chr16:28404153..29353391 [GRCh37] Chr16:28311654..29260892 [NCBI36] Chr16:16p12.1-11.2	pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28327346-29342070)x1	copy number loss	See cases [RCV000137848]	Chr16:28327346..29342070 [GRCh38] Chr16:28338667..29353391 [GRCh37] Chr16:28246168..29260892 [NCBI36] Chr16:16p12.1-11.2	pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28392026-29170879)x3	copy number gain	See cases [RCV000139217]	Chr16:28392026..29170879 [GRCh38] Chr16:28403347..29182200 [GRCh37] Chr16:28310848..29089701 [NCBI36] Chr16:16p12.1-11.2	uncertain significance
GRCh38/hg38 16p12.1-11.2(chr16:28392832-30320693)x1	copy number loss	See cases [RCV000139916]	Chr16:28392832..30320693 [GRCh38] Chr16:28404153..30332014 [GRCh37] Chr16:28311654..30239515 [NCBI36] Chr16:16p12.1-11.2	pathogenic
GRCh38/hg38 16p12.2-11.2(chr16:21350622-29202837)x3	copy number gain	See cases [RCV000140235]	Chr16:21350622..29202837 [GRCh38] Chr16:21361943..29214158 [GRCh37] Chr16:21269444..29121659 [NCBI36] Chr16:16p12.2-11.2	likely pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:27311746-31193406)x3	copy number gain	See cases [RCV000140341]	Chr16:27311746..31193406 [GRCh38] Chr16:27323067..31204727 [GRCh37] Chr16:27230568..31112228 [NCBI36] Chr16:16p12.1-11.2	pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28392832-29320029)x1	copy number loss	See cases [RCV000139466]	Chr16:28392832..29320029 [GRCh38] Chr16:28404153..29331350 [GRCh37] Chr16:28311654..29238851 [NCBI36] Chr16:16p12.1-11.2	pathogenic
GRCh38/hg38 16p12.2-11.2(chr16:23752047-31943755)x3	copy number gain	See cases [RCV000141141]	Chr16:23752047..31943755 [GRCh38] Chr16:23763368..31955076 [GRCh37] Chr16:23670869..31862577 [NCBI36] Chr16:16p12.2-11.2	pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28392832-29170875)x1	copy number loss	See cases [RCV000140694]	Chr16:28392832..29170875 [GRCh38] Chr16:28404153..29182196 [GRCh37] Chr16:28311654..29089697 [NCBI36] Chr16:16p12.1-11.2	pathogenic
GRCh38/hg38 16p12.1-11.2(chr16:28320366-29415078)x3	copy number gain	See cases [RCV000141716]	Chr16:28320366..29415078 [GRCh38] Chr16:28331687..29426399 [GRCh37] Chr16:28239188..29333900 [NCBI36] Chr16:16p12.1-11.2	uncertain significance
GRCh37/hg19 16p12.3-11.2(chr16:19590412-29814175)x3	copy number gain	Breast ductal adenocarcinoma [RCV000207226]	Chr16:19590412..29814175 [GRCh37] Chr16:16p12.3-11.2	uncertain significance
GRCh37/hg19 16p13.3-11.2(chr16:1279324-31926800)x3	copy number gain	Breast ductal adenocarcinoma [RCV000207053]	Chr16:1279324..31926800 [GRCh37] Chr16:16p13.3-11.2	uncertain significance
GRCh37/hg19 16p12.3-11.2(chr16:19424115-30142220)x3	copy number gain	See cases [RCV000449403]	Chr16:19424115..30142220 [GRCh37] Chr16:16p12.3-11.2	pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:69193-90274381)x3	copy number gain	See cases [RCV000446684]	Chr16:69193..90274381 [GRCh37] Chr16:16p13.3-q24.3	pathogenic
NC_000016.10:g.(?_28370872)_(29324276_?)del	deletion	Schizophrenia [RCV000416901]	Chr16:28370872..29324276 [GRCh38] Chr16:28382193..29335597 [GRCh37] Chr16:28289694..29243098 [NCBI36] Chr16:16p12.1-11.2	likely pathogenic
GRCh37/hg19 16p11.2(chr16:28384463-29343462)x1	copy number loss	See cases [RCV000510329]	Chr16:28384463..29343462 [GRCh37] Chr16:16p11.2	pathogenic
GRCh37/hg19 16p13.2-q24.3(chr16:9273328-89548493)x3	copy number gain	See cases [RCV000511622]	Chr16:9273328..89548493 [GRCh37] Chr16:16p13.2-q24.3	uncertain significance
GRCh37/hg19 16p12.2-11.2(chr16:22718350-28858721)x4	copy number gain	See cases [RCV000511587]	Chr16:22718350..28858721 [GRCh37] Chr16:16p12.2-11.2	pathogenic
GRCh37/hg19 16p11.2(chr16:28371467-29426399)x4	copy number gain	See cases [RCV000511109]	Chr16:28371467..29426399 [GRCh37] Chr16:16p11.2	uncertain significance
GRCh37/hg19 16p12.2-11.2(chr16:21596299-30399167)x1	copy number loss	See cases [RCV000511271]	Chr16:21596299..30399167 [GRCh37] Chr16:16p12.2-11.2	pathogenic
maternal UPD(16p)	complex	Hemimegalencephaly [RCV000494707]	Chr16:1280042..33710558 [GRCh37] Chr16:16p13.3-11.2	pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:85881-90155062)x3	copy number gain	See cases [RCV000512138]	Chr16:85881..90155062 [GRCh37] Chr16:16p13.3-q24.3	pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:85881-90155062)	copy number gain	See cases [RCV000511296]	Chr16:85881..90155062 [GRCh37] Chr16:16p13.3-q24.3	pathogenic
GRCh37/hg19 16p12.2-11.2(chr16:21475039-29043958)x1	copy number loss	Chromosome 16p12.2-p11.2 deletion syndrome [RCV003315282]	Chr16:21475039..29043958 [GRCh37] Chr16:16p12.2-11.2	pathogenic
GRCh37/hg19 16p12.3-11.2(chr16:18238275-30177240)x3	copy number gain	See cases [RCV000512428]	Chr16:18238275..30177240 [GRCh37] Chr16:16p12.3-11.2	pathogenic
GRCh37/hg19 16p12.2-11.2(chr16:21379628-29351826)x3	copy number gain	See cases [RCV000512478]	Chr16:21379628..29351826 [GRCh37] Chr16:16p12.2-11.2	pathogenic
GRCh37/hg19 16p11.2(chr16:28389576-29438326)x1	copy number loss	not provided [RCV000683798]	Chr16:28389576..29438326 [GRCh37] Chr16:16p11.2	pathogenic
GRCh37/hg19 16p12.2-11.2(chr16:21379628-29379768)x1	copy number loss	not provided [RCV000683786]	Chr16:21379628..29379768 [GRCh37] Chr16:16p12.2-11.2	pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:88165-90274695)x3	copy number gain	not provided [RCV000738918]	Chr16:88165..90274695 [GRCh37] Chr16:16p13.3-q24.3	pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:61451-90294632)x3	copy number gain	not provided [RCV000738915]	Chr16:61451..90294632 [GRCh37] Chr16:16p13.3-q24.3	pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:88165-90163275)x3	copy number gain	not provided [RCV000738917]	Chr16:88165..90163275 [GRCh37] Chr16:16p13.3-q24.3	pathogenic
NC_000016.10:g.(?_28351819)_(29325073_?)del	deletion	Schizophrenia [RCV000754181]	Chr16:28351819..29325073 [GRCh38] Chr16:16p12.1-11.2	pathogenic
GRCh37/hg19 16p12.2-11.2(chr16:21576802-29351826)x3	copy number gain	not provided [RCV001006786]	Chr16:21576802..29351826 [GRCh37] Chr16:16p12.2-11.2	pathogenic
GRCh37/hg19 16p11.2(chr16:28371467-29416001)x3	copy number gain	not provided [RCV000846620]	Chr16:28371467..29416001 [GRCh37] Chr16:16p11.2	pathogenic
NC_000016.9:g.(?_27441393)_(28899063_?)del	deletion	not provided [RCV003105580]	Chr16:27441393..28899063 [GRCh37] Chr16:16p12.1-11.2	uncertain significance
GRCh37/hg19 16p13.3-11.2(chr16:4380767-30445350)x3	copy number gain	not provided [RCV002472599]	Chr16:4380767..30445350 [GRCh37] Chr16:16p13.3-11.2	pathogenic
GRCh37/hg19 16p12.2-11.2(chr16:21312200-29646379)x3	copy number gain	not provided [RCV001249228]	Chr16:21312200..29646379 [GRCh37] Chr16:16p12.2-11.2	not provided
GRCh37/hg19 16p13.3-11.2(chr16:5805001-34230001)	copy number gain	Microcephaly [RCV001252948]	Chr16:5805001..34230001 [GRCh37] Chr16:16p13.3-11.2	pathogenic
GRCh37/hg19 16p13.3-11.2(chr16:2959279-30190593)x3	copy number gain	See cases [RCV001263169]	Chr16:2959279..30190593 [GRCh37] Chr16:16p13.3-11.2	pathogenic\|likely pathogenic
GRCh37/hg19 16p11.2(chr16:28336673-29358712)x1	copy number loss	not provided [RCV001258615]	Chr16:28336673..29358712 [GRCh37] Chr16:16p11.2	pathogenic
GRCh37/hg19 16p11.2(chr16:28349949-29342589)	copy number loss	Distal 16p11.2 microdeletion syndrome [RCV002280653]	Chr16:28349949..29342589 [GRCh37] Chr16:16p11.2	pathogenic
NC_000016.9:g.21530207_29332245del	deletion	not provided [RCV001030428]	Chr16:21530207..29332245 [GRCh37] Chr16:16p12.2-11.2	pathogenic
GRCh37/hg19 16p11.2(chr16:28384463-29343462)x3	copy number gain	not provided [RCV001258621]	Chr16:28384463..29343462 [GRCh37] Chr16:16p11.2	uncertain significance
GRCh37/hg19 16p12.2-11.2(chr16:21594997-29625302)x1	copy number loss	not provided [RCV001795549]	Chr16:21594997..29625302 [GRCh37] Chr16:16p12.2-11.2	pathogenic
GRCh37/hg19 16p11.2(chr16:28353878-29478115)x3	copy number gain	Distal 16p11.2 microdeletion syndrome [RCV001801190]	Chr16:28353878..29478115 [GRCh37] Chr16:16p11.2	likely pathogenic
GRCh37/hg19 16p11.2(chr16:28384465-29351826)x3	copy number gain	not provided [RCV001827743]	Chr16:28384465..29351826 [GRCh37] Chr16:16p11.2	uncertain significance
NC_000016.9:g.(?_27441393)_(29001333_?)del	deletion	Neuronal ceroid lipofuscinosis [RCV003122400]	Chr16:27441393..29001333 [GRCh37] Chr16:16p12.1-11.2	pathogenic
GRCh37/hg19 16p11.2(chr16:28384464-29432245)x3	copy number gain	not provided [RCV002474709]	Chr16:28384464..29432245 [GRCh37] Chr16:16p11.2	uncertain significance
GRCh37/hg19 16p12.2-11.2(chr16:21576803-30177240)x3	copy number gain	not provided [RCV002474541]	Chr16:21576803..30177240 [GRCh37] Chr16:16p12.2-11.2	pathogenic
GRCh37/hg19 16p11.2(chr16:28371468-29342589)x3	copy number gain	not provided [RCV002475767]	Chr16:28371468..29342589 [GRCh37] Chr16:16p11.2	uncertain significance
NM_001317857.2(EIF3CL):c.962A>G (p.Lys321Arg)	single nucleotide variant	not specified [RCV004196991]	Chr16:28391833 [GRCh38] Chr16:28403154 [GRCh37] Chr16:16p12.1	uncertain significance
NM_001317857.2(EIF3CL):c.916C>T (p.Arg306Trp)	single nucleotide variant	not specified [RCV004072477]	Chr16:28392003 [GRCh38] Chr16:28403324 [GRCh37] Chr16:16p12.1	uncertain significance
NM_001317857.2(EIF3CL):c.800A>G (p.Lys267Arg)	single nucleotide variant	not specified [RCV004121712]	Chr16:28392119 [GRCh38] Chr16:28403440 [GRCh37] Chr16:16p12.1	uncertain significance
NM_001317857.2(EIF3CL):c.992T>G (p.Ile331Ser)	single nucleotide variant	not specified [RCV004249185]	Chr16:28391803 [GRCh38] Chr16:28403124 [GRCh37] Chr16:16p12.1	uncertain significance
GRCh37/hg19 16p11.2(chr16:28371467-29379768)x1	copy number loss	not specified [RCV003987151]	Chr16:28371467..29379768 [GRCh37] Chr16:16p11.2	pathogenic
NM_001317857.2(EIF3CL):c.890A>G (p.Asn297Ser)	single nucleotide variant	not specified [RCV004377782]	Chr16:28392029 [GRCh38] Chr16:28403350 [GRCh37] Chr16:16p12.1	uncertain significance
NM_001317857.2(EIF3CL):c.910A>G (p.Arg304Gly)	single nucleotide variant	not specified [RCV004377783]	Chr16:28392009 [GRCh38] Chr16:28403330 [GRCh37] Chr16:16p12.1	uncertain significance
GRCh37/hg19 16p11.2(chr16:28379443-28487213)x1	copy number loss	not provided [RCV000751639]	Chr16:28379443..28487213 [GRCh37] Chr16:16p11.2	benign
GRCh37/hg19 16p11.2(chr16:28379443-28484556)x1	copy number loss	not provided [RCV000751637]	Chr16:28379443..28484556 [GRCh37] Chr16:16p11.2	benign
GRCh37/hg19 16p11.2(chr16:28379443-28485141)x1	copy number loss	not provided [RCV000751638]	Chr16:28379443..28485141 [GRCh37] Chr16:16p11.2	benign

Predicted Target Of

	Summary Value
Count of predictions:	393
Count of miRNA genes:	128
Interacting mature miRNAs:	133
Transcripts:	ENST00000380876, ENST00000398943, ENST00000398944
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
597346571	GWAS1442645_H	body mass index QTL GWAS1442645 (human)		5e-15	body mass index	body mass index (BMI) (CMO:0000105)	16	28392150	28392151	Human
597283819	GWAS1379893_H	C-reactive protein measurement QTL GWAS1379893 (human)		2e-10	C-reactive protein measurement	blood C-reactive protein level (CMO:0003160)	16	28392150	28392151	Human
596982794	GWAS1102313_H	telomere length QTL GWAS1102313 (human)		1e-13	telomere length		16	28402196	28402197	Human

D16S2553E

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	16	28,735,980 - 28,736,330	UniSTS	GRCh37
GRCh37	16	28,401,615 - 28,401,965	UniSTS	GRCh37
Build 36	16	28,309,116 - 28,309,466	RGD	NCBI36
Celera	16	28,069,877 - 28,070,227	RGD
Cytogenetic Map	16	p11.2	UniSTS
HuRef	16	26,460,765 - 26,461,115	UniSTS

D16S2774

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	16	28,719,398 - 28,719,548	UniSTS	GRCh37
GRCh37	16	28,418,399 - 28,418,549	UniSTS	GRCh37
Build 36	16	28,325,900 - 28,326,050	RGD	NCBI36
Celera	16	28,086,652 - 28,086,802	RGD
Cytogenetic Map	16	p11.2	UniSTS

D16S2882

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	16	28,713,580 - 28,713,730	UniSTS	GRCh37
GRCh37	16	28,424,226 - 28,424,376	UniSTS	GRCh37
Build 36	16	28,331,727 - 28,331,877	RGD	NCBI36
Celera	16	28,092,459 - 28,092,609	RGD
Cytogenetic Map	16	p11.2	UniSTS
HuRef	16	26,483,546 - 26,483,696	UniSTS

SGC31754

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	16	28,746,774 - 28,746,906	UniSTS	GRCh37
GRCh37	16	28,391,047 - 28,391,179	UniSTS	GRCh37
Build 36	16	28,298,548 - 28,298,680	RGD	NCBI36
Celera	16	28,059,300 - 28,059,432	RGD
Cytogenetic Map	16	p11.2	UniSTS
HuRef	16	26,450,193 - 26,450,325	UniSTS
Whitehead-RH Map	16	137.6	UniSTS
NCBI RH Map	16	232.2	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	entire extraembryonic component	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system
1204	2418	2788	2243	4932	1671	2290	4	571	1912	413	2268	7163	6411	51	3699	827	1711	1608	170


RefSeq Transcripts	NM_001099661	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001317856	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001317857	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017023620	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017023621	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_047434558	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054313817	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054313818	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054313819	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054313820	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC138894	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BQ686089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068262	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DA645577	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DC410988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000380876 ⟹ ENSP00000370258

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	28,379,715 - 28,403,841 (-)	Ensembl

Ensembl Acc Id:

ENST00000398944 ⟹ ENSP00000381917

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	28,379,579 - 28,403,841 (-)	Ensembl

RefSeq Acc Id:

NM_001099661 ⟹ NP_001093131

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	16	28,379,581 - 28,403,885 (-)	NCBI
GRCh37	16	28,390,900 - 28,415,162 (-)	ENTREZGENE
Build 36	16	28,298,401 - 28,322,663 (-)	NCBI Archive
HuRef	16	26,450,046 - 26,474,307 (-)	ENTREZGENE
CHM1_1	16	29,404,044 - 29,426,953 (-)	NCBI
T2T-CHM13v2.0	16	28,659,992 - 28,684,228 (-)	NCBI

Sequence:

show sequence

GTAGTTAGTCGGCGCTTCCCGGAAGTGACGCGAGGACCCGCCTTCTCTCTCGGCGTTTCCGCTGTCAGGGCCCTGCGGTGTGACTCGCGGGCTCAGCTGGTTGGTCCGGCCGTAGCACCTCCGCGCCG
TCGCCATGTCGCGGTTTTTCACCACCGGTTCGGACAGCGAGTCCGAGTCGTCCTTGTCCGGGGAGGAGCTCGTCACCAAACCTGTCGGAGGCAACTATGGCAAACAGCCATTGTTGCTGAGCGAGGAT
GAAGAAGATACCAAGAGAGTTGTCCGCAGTGCCAAGGACAAGAGGTTTGAGGAGCTGACCAACCTTATCCGGACCATCCGTAATGCCATGAAGATTCGTGATGTCACCAAGTGCCTGGAAGAGTTTGA
GCTCCTGGGAAAAGCATATGGGAAGGCCAAAAGCATTGTGGACAAAGAAGGTGTCCCCCGGTTCTATATCCGCATCCTGGCTGACCTAGAGGACTATCTTAATGAGCTTTGGGAAGATAAGGAAGGGA
AGAAGAAGATGAACAAGAACAATGCCAAGGCTCTGAGCACCTTGCGTCAGAAGATCCGAAAATACAACCGTGATTTCGAGTCCCATATCACAAGCTACAAGCAGAACCCCGAGCAGTCTGCGGATGAA
GATGCTGAGAAAAATGAGGAGGATTCAGAAGGCTCTTCAGATGAGGATGAGGATGAGGACGGAGTCAGTGCTGCAACTTTCTTGAAGAAGAAATCAGAAGCTCCTTCTGGGGAGAGTCGCAAGTTCCT
CAAAAAGATGGATGATGAAGATGAGGACTCAGAAGATTCCGAAGATGATGAAGACTGGGACACAGGTTCCACATCTTCCGATTCCGACTCAGAGGAGGAAGAAGGGAAACAAACCGCGCTGGCCTCAA
GATTTCTTAAAAAGGCACCCACCACAGATGAGGACAAGAAGGCAGCCGAGAAGAAACGGGAGGACAAAGCTAAGAAGAAGCACGACAGGAAATCCAAGCGCCTGGATGAGGAGGAGGAGGAGGACAAT
GAAGGCGGGGAGTGGGAAAGGGTCCGGGGCGGAGTGCCGTTGGTTAAGGAGAAGCCAAAAATGTTTGCCAAGGGAACTGAGATCACCCATGCTGTTGTTATCAAGAAACTGAATGAGATCCTACAGGC
ACGAGGCAAGAAGGGAACTGATCGTGCTGCCCAGATTGAGCTGCTGCAACTGCTGGTTCAGATTGCAGCGGAAAACAACCTGGGAGAGGGCGTCATTGTCAAGATCAAGTTCAATATCATCGCCTCTC
TCTATGACTACAACCCCAACCTGGCAACCTACATGAAGCCAGAGATGTGGGGGAAGTGCCTGGACTGCATCAATGAGCTGATGGATATCCTGTTTGCAAATCCCAACATTTTTGTTGGAGAGAATATT
CTGGAAGAGAGTGAGAACCTGCACAACGCTGACCAGCCACTGCGTGTCCGTGGCTGCATCCTAACTCTGGTGGAACGAATGGATGAAGAATTTACCAAAATAATGCAAAATACTGACCCTCACTCCCA
AGAGTACGTGGAGCACTTGAAGGATGAGGCCCAGGTGTGTGCCATCATCGAGCGTGTGCAGCGCTACCTGGAGGAGAAGGGCACTACCGAGGAGGTCTGCCGCATCTACCTGCTGCGCATCCTGCACA
CCTACTACAAGTTTGATTACAAGGCCCATCAGCGACAGCTGACCCCGCCTGAGGGCTCCTCAAAGTCTGAGCAAGACCAGGCAGAAAATGAGGGCGAGGACTCGGCTGTGTTGATGGAGAGACTGTGC
AAGTACATCTACGCCAAGGACCGCACAGACCGGATCCGCACATGTGCCATCCTCTGCCACATCTACCACCATGCTCTGCACTCGCGCTGGTACCAGGCCCGCGACCTCATGCTCATGAGCCACTTGCA
GGACAACATTCAGCATGCAGACCCGCCAGTGCAGATCCTTTACAACCGCACCATGGTGCAGCTGGGCATCTGTGCCTTCCGCCAAGGCCTGACCAAGGACGCACACAACGCCCTGCTGGACATCCAGT
CGAGTGGCCGAGCCAAGGAGCTTCTGGGCCAGGGCCTGCTGCTGCGCAGCCTGCAGGAGCGCAACCAGGAGCAGGAGAAGGTGGAGCGGCGCCGTCAGGTCCCCTTCCACCTGCACATCAACCTGGAG
CTGCTGGAGTGTGTCTACCTGGTGTCTGCCATGCTCCTGGAGATCCCCTACATGGCCGCCCATGAGAGCGATGCCCGCCGACGCATGATCAGCAAGCAGTTCCACCACCAGCTGCGCGTGGGCGAGCG
ACAGCCCCTGCTGGGTCCCCCTGAGTCCATGCGGGAACATGTGGTCGCTGCCTCCAAGGCCATGAAGATGGGTGACTGGAAGACCTGTCACAGTTTTATCATCAATGAGAAGATGAATGGGAAAGTGT
GGGACCTTTTCCCCGAGGCTGACAAAGTCCGCACCATGCTGGTTAGGAAGATCCAGGAAGAGTCACTGAGGACCTACCTCTTCACCTACAGCAGTGTCTATGACTCCATCAGCATGGAGACGCTGTCA
GACATGTTTGAGCTGGATCTGCCCACTGTGCACTCCATCATCAGCAAAATGATCATTAATGAGGAGCTGATGGCCTCCCTGGACCAGCCAACACAGACAGTGGTGATGCACCGCACTGAGCCCACTGC
CCAGCAGAACCTGGCTCTGCAGCTGGCCGAGAAGCTGGGCAGCCTGGTGGAGAACAACGAACGGGTGTTTGACCACAAGCAGGGCACCTACGGGGGCTACTTCCGAGACCAGAAGGACGGCTACCGCA
AAAACGAGGGCTACATGCGCCGCGGTGGCTACCGCCAGCAGCAGTCTCAGACGGCCTACTGAGCTCTCCACTCTGTTTCCCGCCTGGGCCATCCAACCTTGAAGTCCTAAACCACACCTCAGTCACTA
AAGGTCTGTTTAAAGTTGTTCTGGTTGATTGCTTGTTGCCACAAAGGTGTGTTGAGCCCATTCATTTGCTGATTATATTTCTGAGCTGCTACCACATGACAGACACAAGGCTCAGATGAAGAGGTGAA
TTGAACACGTTCCTGACCTCAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001317856 ⟹ NP_001304785

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	16	28,379,581 - 28,403,885 (-)	NCBI
CHM1_1	16	29,404,044 - 29,426,953 (-)	NCBI
T2T-CHM13v2.0	16	28,659,992 - 28,684,228 (-)	NCBI

Sequence:

show sequence

GTAGTTAGTCGGCGCTTCCCGGAAGTGACGCGAGGACCCGCCTTCTCTCTCGGCGTTTCCGCTG
TCAGGGCCCTGCGGTGTGACTCGCGGGCTCAGCTGGTTGGTATTTTTTGGGCCTCGTGCTTCGTGGTGGGAGACCCAGGTCGAGGTCCGGCCGTAGCACCTCCGCGCCGTCGCCATGTCGCGGTTTTT
CACCACCGGTTCGGACAGCGAGTCCGAGTCGTCCTTGTCCGGGGAGGAGCTCGTCACCAAACCTGTCGGAGGCAACTATGGCAAACAGCCATTGTTGCTGAGCGAGGATGAAGAAGATACCAAGAGAG
TTGTCCGCAGTGCCAAGGACAAGAGGTTTGAGGAGCTGACCAACCTTATCCGGACCATCCGTAATGCCATGAAGATTCGTGATGTCACCAAGTGCCTGGAAGAGTTTGAGCTCCTGGGAAAAGCATAT
GGGAAGGCCAAAAGCATTGTGGACAAAGAAGGTGTCCCCCGGTTCTATATCCGCATCCTGGCTGACCTAGAGGACTATCTTAATGAGCTTTGGGAAGATAAGGAAGGGAAGAAGAAGATGAACAAGAA
CAATGCCAAGGCTCTGAGCACCTTGCGTCAGAAGATCCGAAAATACAACCGTGATTTCGAGTCCCATATCACAAGCTACAAGCAGAACCCCGAGCAGTCTGCGGATGAAGATGCTGAGAAAAATGAGG
AGGATTCAGAAGGCTCTTCAGATGAGGATGAGGATGAGGACGGAGTCAGTGCTGCAACTTTCTTGAAGAAGAAATCAGAAGCTCCTTCTGGGGAGAGTCGCAAGTTCCTCAAAAAGATGGATGATGAA
GATGAGGACTCAGAAGATTCCGAAGATGATGAAGACTGGGACACAGGTTCCACATCTTCCGATTCCGACTCAGAGGAGGAAGAAGGGAAACAAACCGCGCTGGCCTCAAGATTTCTTAAAAAGGCACC
CACCACAGATGAGGACAAGAAGGCAGCCGAGAAGAAACGGGAGGACAAAGCTAAGAAGAAGCACGACAGGAAATCCAAGCGCCTGGATGAGGAGGAGGAGGAGGACAATGAAGGCGGGGAGTGGGAAA
GGGTCCGGGGCGGAGTGCCGTTGGTTAAGGAGAAGCCAAAAATGTTTGCCAAGGGAACTGAGATCACCCATGCTGTTGTTATCAAGAAACTGAATGAGATCCTACAGGCACGAGGCAAGAAGGGAACT
GATCGTGCTGCCCAGATTGAGCTGCTGCAACTGCTGGTTCAGATTGCAGCGGAAAACAACCTGGGAGAGGGCGTCATTGTCAAGATCAAGTTCAATATCATCGCCTCTCTCTATGACTACAACCCCAA
CCTGGCAACCTACATGAAGCCAGAGATGTGGGGGAAGTGCCTGGACTGCATCAATGAGCTGATGGATATCCTGTTTGCAAATCCCAACATTTTTGTTGGAGAGAATATTCTGGAAGAGAGTGAGAACC
TGCACAACGCTGACCAGCCACTGCGTGTCCGTGGCTGCATCCTAACTCTGGTGGAACGAATGGATGAAGAATTTACCAAAATAATGCAAAATACTGACCCTCACTCCCAAGAGTACGTGGAGCACTTG
AAGGATGAGGCCCAGGTGTGTGCCATCATCGAGCGTGTGCAGCGCTACCTGGAGGAGAAGGGCACTACCGAGGAGGTCTGCCGCATCTACCTGCTGCGCATCCTGCACACCTACTACAAGTTTGATTA
CAAGGCCCATCAGCGACAGCTGACCCCGCCTGAGGGCTCCTCAAAGTCTGAGCAAGACCAGGCAGAAAATGAGGGCGAGGACTCGGCTGTGTTGATGGAGAGACTGTGCAAGTACATCTACGCCAAGG
ACCGCACAGACCGGATCCGCACATGTGCCATCCTCTGCCACATCTACCACCATGCTCTGCACTCGCGCTGGTACCAGGCCCGCGACCTCATGCTCATGAGCCACTTGCAGGACAACATTCAGCATGCA
GACCCGCCAGTGCAGATCCTTTACAACCGCACCATGGTGCAGCTGGGCATCTGTGCCTTCCGCCAAGGCCTGACCAAGGACGCACACAACGCCCTGCTGGACATCCAGTCGAGTGGCCGAGCCAAGGA
GCTTCTGGGCCAGGGCCTGCTGCTGCGCAGCCTGCAGGAGCGCAACCAGGAGCAGGAGAAGGTGGAGCGGCGCCGTCAGGTCCCCTTCCACCTGCACATCAACCTGGAGCTGCTGGAGTGTGTCTACC
TGGTGTCTGCCATGCTCCTGGAGATCCCCTACATGGCCGCCCATGAGAGCGATGCCCGCCGACGCATGATCAGCAAGCAGTTCCACCACCAGCTGCGCGTGGGCGAGCGACAGCCCCTGCTGGGTCCC
CCTGAGTCCATGCGGGAACATGTGGTCGCTGCCTCCAAGGCCATGAAGATGGGTGACTGGAAGACCTGTCACAGTTTTATCATCAATGAGAAGATGAATGGGAAAGTGTGGGACCTTTTCCCCGAGGC
TGACAAAGTCCGCACCATGCTGGTTAGGAAGATCCAGGAAGAGTCACTGAGGACCTACCTCTTCACCTACAGCAGTGTCTATGACTCCATCAGCATGGAGACGCTGTCAGACATGTTTGAGCTGGATC
TGCCCACTGTGCACTCCATCATCAGCAAAATGATCATTAATGAGGAGCTGATGGCCTCCCTGGACCAGCCAACACAGACAGTGGTGATGCACCGCACTGAGCCCACTGCCCAGCAGAACCTGGCTCTG
CAGCTGGCCGAGAAGCTGGGCAGCCTGGTGGAGAACAACGAACGGGTGTTTGACCACAAGCAGGGCACCTACGGGGGCTACTTCCGAGACCAGAAGGACGGCTACCGCAAAAACGAGGGCTACATGCG
CCGCGGTGGCTACCGCCAGCAGCAGTCTCAGACGGCCTACTGAGCTCTCCACTCTGTTTCCCGCCTGGGCCATCCAACCTTGAAGTCCTAAACCACACCTCAGTCACTAAAGGTCTGTTTAAAGTTGT
TCTGGTTGATTGCTTGTTGCCACAAAGGTGTGTTGAGCCCATTCATTTGCTGATTATATTTCTGAGCTGCTACCACATGACAGACACAAGGCTCAGATGAAGAGGTGAATTGAACACGTTCCTGACCT
CAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001317857 ⟹ NP_001304786

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	16	28,379,715 - 28,403,841 (-)	NCBI
CHM1_1	16	29,404,044 - 29,426,953 (-)	NCBI
T2T-CHM13v2.0	16	28,660,126 - 28,684,184 (-)	NCBI

Sequence:

show sequence

CTCTCTCGGCGTTTCCGCTGTCAGGGCCCTGCGGTGTGACTCGCGGGCTCAGCTGGTCCGGCCG
TAGCACCTCCGCGCCGTCGCCATGTCGCGGTTTTTCACCACCGGTTCGGACAGCGAGTCCGAGTCGTCCTTGTCCGGGGAGGAGCTCGTCACCAAACCTGTCGGAGGCAACTATGGCAAACAGCCATT
GTTGCTGAGCGAGGATGAAGAAGATACCAAGAGAGTTGTCCGCAGTGCCAAGGACAAGAGGTTTGAGGAGCTGACCAACCTTATCCGGACCATCCGTAATGCCATGAAGATTCGTGATGTCACCAAGT
GCCTGGAAGAGTTTGAGCTCCTGGGAAAAGCATATGGGAAGGCCAAAAGCATTGTGGACAAAGAAGGTGTCCCCCGGTTCTATATCCGCATCCTGGCTGACCTAGAGGACTATCTTAATGAGCTTTGG
GAAGATAAGGAAGGGAAGAAGAAGATGAACAAGAACAATGCCAAGGCTCTGAGCACCTTGCGTCAGAAGATCCGAAAATACAACCGTGATTTCGAGTCCCATATCACAAGCTACAAGCAGAACCCCGA
GCAGTCTGCGGATGAAGATGCTGAGAAAAATGAGGAGGATTCAGAAGGCTCTTCAGATGAGGATGAGGATGAGGACGGAGTCAGTGCTGCAACTTTCTTGAAGAAGAAATCAGAAGCTCCTTCTGGGG
AGAGTCGCAAGTTCCTCAAAAAGATGGATGATGAAGATGAGGACTCAGAAGATTCCGAAGATGATGAAGACTGGGACACAGGTTCCACATCTTCCGATTCCGACTCAGAGGAGGAAGAAGGGAAACAA
ACCGCGCTGGCCTCAAGATTTCTTAAAAAGGCACCCACCACAGATGAGGACAAGAAGGCAGCCGAGAAGAAACGGGAGGACAAAGCTAAGAAGAAGCACGACAGGAAATCCAAGCGCCTGGATGAGGA
GGAGGAGGAGGACAATGAAGGCGGGGAGTGGGAAAGGGTCCGGGGCGGAGTGCCGTTGGTTAAGGAGAAGCCAAAAATGTTTGCCAAGGGAACTGAGATCACCCATGCTGTTGTTATCAAGAAACTGA
ATGAGATCCTACAGGCACGAGGCAAGAAGGGAACTGATCGTGCTGCCCAGATTGAGCTGCTGCAACTGCTGGTTCAGATTGCAGCGGAAAACAACCTGGGAGAGGGCGTCATTGTCAAGATCAAGTTC
AATATCATCGCCTCTCTCTATGACTACAACCCCAACCTGGCAACCTACATGAAGCCAGAGATGTGGGGGAAGTGCCTGGACTGCATCAATGAGCTGATGGATATCCTGTTTGCAAATCCCAACATTTT
TGTTGGAGAGAATATTCTGGAAGAGAGTGAGAACCTGCACAACGCTGACCAGCCACTGCGTGTCCGTGGCTGCATCCTAACTCTGGTGGAACGAATGGATGAAGAATTTACCAAAATAATGCAAAATA
CTGACCCTCACTCCCAAGAGTACGTGGAGCACTTGAAGGATGAGGCCCAGGTGTGTGCCATCATCGAGCGTGTGCAGCGCTACCTGGAGGAGAAGGGCACTACCGAGGAGGTCTGCCGCATCTACCTG
CTGCGCATCCTGCACACCTACTACAAGTTTGATTACAAGGCCCATCAGCGACAGCTGACCCCGCCTGAGGGCTCCTCAAAGTCTGAGCAAGACCAGGCAGAAAATGAGGGCGAGGACTCGGCTGTGTT
GATGGAGAGACTGTGCAAGTACATCTACGCCAAGGACCGCACAGACCGGATCCGCACATGTGCCATCCTCTGCCACATCTACCACCATGCTCTGCACTCGCGCTGGTACCAGGCCCGCGACCTCATGC
TCATGAGCCACTTGCAGGACAACATTCAGCATGCAGACCCGCCAGTGCAGATCCTTTACAACCGCACCATGGTGCAGCTGGGCATCTGTGCCTTCCGCCAAGGCCTGACCAAGGACGCACACAACGCC
CTGCTGGACATCCAGTCGAGTGGCCGAGCCAAGGAGCTTCTGGGCCAGGGCCTGCTGCTGCGCAGCCTGCAGGAGCGCAACCAGGAGCAGGAGAAGGTGGAGCGGCGCCGTCAGGTCCCCTTCCACCT
GCACATCAACCTGGAGCTGCTGGAGTGTGTCTACCTGGTGTCTGCCATGCTCCTGGAGATCCCCTACATGGCCGCCCATGAGAGCGATGCCCGCCGACGCATGATCAGCAAGCAGTTCCACCACCAGC
TGCGCGTGGGCGAGCGACAGCCCCTGCTGGGTCCCCCTGAGTCCATGCGGGAACATGTGGTCGCTGCCTCCAAGGCCATGAAGATGGGTGACTGGAAGACCTGTCACAGTTTTATCATCAATGAGAAG
ATGAATGGGAAAGTGTGGGACCTTTTCCCCGAGGCTGACAAAGTCCGCACCATGCTGGTTAGGAAGATCCAGGAAGAGTCACTGAGGACCTACCTCTTCACCTACAGCAGTGTCTATGACTCCATCAG
CATGGAGACGCTGTCAGACATGTTTGAGCTGGATCTGCCCACTGTGCACTCCATCATCAGCAAAATGATCATTAATGAGGAGCTGATGGCCTCCCTGGACCAGCCAACACAGACAGTGGTGATGCACC
GCACTGAGCCCACTGCCCAGCAGAACCTGGCTCTGCAGCTGGCCGAGAAGCTGGGCAGCCTGGTGGAGAACAACGAACGGGTGTTTGACCACAAGCAGGGCACCTACGGGGGCTACTTCCGAGACCAG
AAGGACGGCTACCGCAAAAACGAGGGCTACATGCGCCGCGGTGGCTACCGCCAGCAGCAGTCTCAGACGGCCTACTGAGCTCTCCACTCTGTTTCCCGCCTGGGCCATCCAACCTTGAAGTCCTAAAC
CACACCTCAGTCACTAAAGGTCTGTTTAAAGTT

hide sequence

RefSeq Acc Id:

XM_017023620 ⟹ XP_016879109

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	16	28,379,976 - 28,403,841 (-)	NCBI

Sequence:

show sequence

CTTCTCTCTCGGCGTTTCCGCTGTCAGGGCCCTGCGGTGTGACTCGCGGGCTCAGCTGGTCCGG
CCGTAGCACCTCCGCGCCGTCGCCATGTCGCGGTTTTTCACCACCGGTTCGGACAGCGAGTCCGAGTCGTCCTTGTCCGGGGAGGAGCTCGTCACCAAACCTGTCGGAGGCAACTATGGCAAACAGCC
ATTGTTGCTGAGCGAGGATGAAGAAGATACCAAGAGAGTTGTCCGCAGTGCCAAGGACAAGAGGTTTGAGGAGCTGACCAACCTTATCCGGACCATCCGTAATGCCATGAAGATTCGTGATGTCACCA
AGTGCCTGGAAGAGTTTGAGCTCCTGGGAAAAGCATATGGGAAGGCCAAAAGCATTGTGGACAAAGAAGGTGTCCCCCGGTTCTATATCCGCATCCTGGCTGACCTAGAGGACTATCTTAATGAGCTT
TGGGAAGATAAGGAAGGGAAGAAGAAGATGAACAAGAACAATGCCAAGGCTCTGAGCACCTTGCGTCAGAAGATCCGAAAATACAACCGTGATTTCGAGTCCCATATCACAAGCTACAAGCAGAACCC
CGAGCAGTCTGCGGATGAAGATGCTGAGAAAAATGAGGAGGATTCAGAAGGCTCTTCAGATGAGGATGAGGATGAGGACGGAGTCAGTGCTGCAACTTTCTTGAAGAAGAAATCAGAAGCTCCTTCTG
GGGAGAGTCGCAAGTTCCTCAAAAAGATGGATGATGAAGATGAGGACTCAGAAGATTCCGAAGATGATGAAGACTGGGACACAGGTTCCACATCTTCCGATTCCGACTCAGAGGAGGAAGAAGGGAAA
CAAACCGCGCTGGCCTCAAGATTTCTTAAAAAGGCACCCACCACAGATGAGGACAAGAAGGCAGCCGAGAAGAAACGGGAGGACAAAGCTAAGAAGAAGCACGACAGGAAATCCAAGCGCCTGGATGA
GGAGGAGGAGGAGGACAATGAAGGCGGGGAGTGGGAAAGGGTCCGGGGCGGAGTGCCGTTGGTTAAGGAGAAGCCAAAAATGTTTGCCAAGGGAACTGAGATCACCCATGCTGTTGTTATCAAGAAAC
TGAATGAGATCCTACAGGCACGAGGCAAGAAGGGAACTGATCGTGCTGCCCAGATTGAGCTGCTGCAACTGCTGGTTCAGATTGCAGCGGAAAACAACCTGGGAGAGGGCGTCATTGTCAAGATCAAG
TTCAATATCATCGCCTCTCTCTATGACTACAACCCCAACCTGGCAACCTACATGAAGCCAGAGATGTGGGGGAAGTGCCTGGACTGCATCAATGAGCTGATGGATATCCTGTTTGCAAATCCCAACAT
TTTTGTTGGAGAGAATATTCTGGAAGAGAGTGAGAACCTGCACAACGCTGACCAGCCACTGCGTGTCCGTGGCTGCATCCTAACTCTGGTGGAACGAATGGATGAAGAATTTACCAAAATAATGCAAA
ATACTGACCCTCACTCCCAAGAGTACGTGGAGCACTTGAAGGATGAGGCCCAGGTGTGTGCCATCATCGAGCGTGTGCAGCGCTACCTGGAGGAGAAGGGCACTACCGAGGAGGTCTGCCGCATCTAC
CTGCTGCGCATCCTGCACACCTACTACAAGTTTGATTACAAGGCCCATCAGCGACAGCTGACCCCGCCTGAGGGCTCCTCAAAGTCTGAGCAAGACCAGGCAGAAAATGAGGGCGAGGACTCGGCTGT
GTTGATGGAGAGACTGTGCAAGTACATCTACGCCAAGGACCGCACAGACCGGATCCGCACATGTGCCATCCTCTGCCACATCTACCACCATGCTCTGCACTCGCGCTGGTACCAGGCCCGCGACCTCA
TGCTCATGAGCCACTTGCAGGACAACATTCAGCATGCAGACCCGCCAGTGCAGATCCTTTACAACCGCACCATGGTGCAGCTGGGCATCTGTGCCTTCCGCCAAGGCCTGACCAAGGACGCACACAAC
GCCCTGCTGGACATCCAGTCGAGTGGCCGAGCCAAGGAGCTTCTGGGCCAGGGCCTGCTGCTGCGCAGCCTGCAGGAGCGCAACCAGGAGCAGGAGAAGGTGGAGCGGCGCCGTCAGGTCCCCTTCCA
CCTGCACATCAACCTGGAGCTGCTGGAGTGTGTCTACCTGGTGTCTGCCATGCTCCTGGAGATCCCCTACATGGCCGCCCATGAGAGCGATGCCCGCCGACGCATGATCAGCAAGCAGTTCCACCACC
AGCTGCGCGTGGGCGAGCGACAGCCCCTGCTGGGTCCCCCTGAGTCCATGCGGGAACATGTGGTCGCTGCCTCCAAGGCCATGAAGATGGGTGACTGGAAGACCTGTCACAGTTTTATCATCAATGAG
AAGATGAATGGGAAAGTGTGGGACCTTTTCCCCGAGGCTGACAAAGTCCGCACCATGCTGGTTAGGAAGATCCAGGAAGAGTCACTGAGGACCTACCTCTTCACCTACAGCAGTGTCTATGACTCCAT
CAGCATGGAGACGCTGTCAGACATGTTTGAGCTGGATCTGCCCACTGTGCACTCCATCATCAGCAAAATGATCATTAATGAGGAGCTGATGGTAGGGGCCGGGGTGGGAAGCGGGCAGGTGGAGCCAT
GGAGGGATTGGAGCAGAGGGGCCTGATCTGTGTCGTGTCCCCTCCTCTGCCTTGGCG

hide sequence

RefSeq Acc Id:

XM_017023621 ⟹ XP_016879110

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	16	28,379,581 - 28,394,291 (-)	NCBI

Sequence:

show sequence

AGTTCTCCTCAGCCTCCCAAGTAGCTGGGATTACAGGGCACCCACCACAGATGAGGACAAGAAG
GCAGCCGAGAAGAAACGGGAGGACAAAGCTAAGAAGAAGCACGACAGGAAATCCAAGCGCCTGGATGAGGAGGAGGAGGAGGACAATGAAGGCGGGGAGTGGGAAAGGGTCCGGGGCGGAGTGCCGTT
GGTTAAGGAGAAGCCAAAAATGTTTGCCAAGGGAACTGAGATCACCCATGCTGTTGTTATCAAGAAACTGAATGAGATCCTACAGGCACGAGGCAAGAAGGGAACTGATCGTGCTGCCCAGATTGAGC
TGCTGCAACTGCTGGTTCAGATTGCAGCGGAAAACAACCTGGGAGAGGGCGTCATTGTCAAGATCAAGTTCAATATCATCGCCTCTCTCTATGACTACAACCCCAACCTGGCAACCTACATGAAGCCA
GAGATGTGGGGGAAGTGCCTGGACTGCATCAATGAGCTGATGGATATCCTGTTTGCAAATCCCAACATTTTTGTTGGAGAGAATATTCTGGAAGAGAGTGAGAACCTGCACAACGCTGACCAGCCACT
GCGTGTCCGTGGCTGCATCCTAACTCTGGTGGAACGAATGGATGAAGAATTTACCAAAATAATGCAAAATACTGACCCTCACTCCCAAGAGTACGTGGAGCACTTGAAGGATGAGGCCCAGGTGTGTG
CCATCATCGAGCGTGTGCAGCGCTACCTGGAGGAGAAGGGCACTACCGAGGAGGTCTGCCGCATCTACCTGCTGCGCATCCTGCACACCTACTACAAGTTTGATTACAAGGCCCATCAGCGACAGCTG
ACCCCGCCTGAGGGCTCCTCAAAGTCTGAGCAAGACCAGGCAGAAAATGAGGGCGAGGACTCGGCTGTGTTGATGGAGAGACTGTGCAAGTACATCTACGCCAAGGACCGCACAGACCGGATCCGCAC
ATGTGCCATCCTCTGCCACATCTACCACCATGCTCTGCACTCGCGCTGGTACCAGGCCCGCGACCTCATGCTCATGAGCCACTTGCAGGACAACATTCAGCATGCAGACCCGCCAGTGCAGATCCTTT
ACAACCGCACCATGGTGCAGCTGGGCATCTGTGCCTTCCGCCAAGGCCTGACCAAGGACGCACACAACGCCCTGCTGGACATCCAGTCGAGTGGCCGAGCCAAGGAGCTTCTGGGCCAGGGCCTGCTG
CTGCGCAGCCTGCAGGAGCGCAACCAGGAGCAGGAGAAGGTGGAGCGGCGCCGTCAGGTCCCCTTCCACCTGCACATCAACCTGGAGCTGCTGGAGTGTGTCTACCTGGTGTCTGCCATGCTCCTGGA
GATCCCCTACATGGCCGCCCATGAGAGCGATGCCCGCCGACGCATGATCAGCAAGCAGTTCCACCACCAGCTGCGCGTGGGCGAGCGACAGCCCCTGCTGGGTCCCCCTGAGTCCATGCGGGAACATG
TGGTCGCTGCCTCCAAGGCCATGAAGATGGGTGACTGGAAGACCTGTCACAGTTTTATCATCAATGAGAAGATGAATGGGAAAGTGTGGGACCTTTTCCCCGAGGCTGACAAAGTCCGCACCATGCTG
GTTAGGAAGATCCAGGAAGAGTCACTGAGGACCTACCTCTTCACCTACAGCAGTGTCTATGACTCCATCAGCATGGAGACGCTGTCAGACATGTTTGAGCTGGATCTGCCCACTGTGCACTCCATCAT
CAGCAAAATGATCATTAATGAGGAGCTGATGGCCTCCCTGGACCAGCCAACACAGACAGTGGTGATGCACCGCACTGAGCCCACTGCCCAGCAGAACCTGGCTCTGCAGCTGGCCGAGAAGCTGGGCA
GCCTGGTGGAGAACAACGAACGGGTGTTTGACCACAAGCAGGGCACCTACGGGGGCTACTTCCGAGACCAGAAGGACGGCTACCGCAAAAACGAGGGCTACATGCGCCGCGGTGGCTACCGCCAGCAG
CAGTCTCAGACGGCCTACTGAGCTCTCCACTCTGTTTCCCGCCTGGGCCATCCAACCTTGAAGTCCTAAACCACACCTCAGTCACTAAAGGTCTGTTTAAAGTTGT

hide sequence

RefSeq Acc Id:

XM_047434558 ⟹ XP_047290514

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	16	28,379,581 - 28,426,418 (-)	NCBI

RefSeq Acc Id:

XM_054313817 ⟹ XP_054169792

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	16	28,659,992 - 28,707,115 (-)	NCBI

RefSeq Acc Id:

XM_054313818 ⟹ XP_054169793

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	16	28,659,992 - 28,707,115 (-)	NCBI

RefSeq Acc Id:

XM_054313819 ⟹ XP_054169794

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	16	28,659,992 - 28,707,115 (-)	NCBI

RefSeq Acc Id:

XM_054313820 ⟹ XP_054169795

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	16	28,659,992 - 28,674,715 (-)	NCBI


Protein RefSeqs	NP_001093131	(Get FASTA)	NCBI Sequence Viewer
	NP_001304785	(Get FASTA)	NCBI Sequence Viewer
	NP_001304786	(Get FASTA)	NCBI Sequence Viewer
	XP_016879109	(Get FASTA)	NCBI Sequence Viewer
	XP_016879110	(Get FASTA)	NCBI Sequence Viewer
	XP_047290514	(Get FASTA)	NCBI Sequence Viewer
	XP_054169792	(Get FASTA)	NCBI Sequence Viewer
	XP_054169793	(Get FASTA)	NCBI Sequence Viewer
	XP_054169794	(Get FASTA)	NCBI Sequence Viewer
	XP_054169795	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	B5ME19	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000370258
	ENSP00000370258.5
	ENSP00000381917
	ENSP00000381917.3

RefSeq Acc Id:

NP_001093131 ⟸ NM_001099661

- UniProtKB:

B5ME19 (UniProtKB/Swiss-Prot), A1KYQ7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNELWEDKEGKK
KMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRF
LKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQIAAENNLGEGVIVKIKFNIIASLY
DYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFVGENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEVCRIYLLRILHTY
YKFDYKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSS
GRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWD
LFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKN
EGYMRRGGYRQQQSQTAY

hide sequence

RefSeq Acc Id:

NP_001304786 ⟸ NM_001317857

- UniProtKB:

B5ME19 (UniProtKB/Swiss-Prot), A1KYQ7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLI
RTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVS
AATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEEDNEGGEWERVRGGVPLVKEKPKMFA
KGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQIAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFVGENILEESENLHNADQPLRVRGCILTL
VERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYH
HALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHES
DARRRMISKQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEEL
MASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYMRRGGYRQQQSQTAY

hide sequence

RefSeq Acc Id:

NP_001304785 ⟸ NM_001317856

- UniProtKB:

B5ME19 (UniProtKB/Swiss-Prot), A1KYQ7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNELWEDKEGKK
KMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRF
LKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQIAAENNLGEGVIVKIKFNIIASLY
DYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFVGENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEVCRIYLLRILHTY
YKFDYKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSS
GRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWD
LFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKN
EGYMRRGGYRQQQSQTAY

hide sequence

RefSeq Acc Id:	XP_016879110 ⟸ XM_017023621
- Peptide Label:	isoform X3
- UniProtKB:	B3KNZ4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQIAAENNLGEGVIVKIKFNIIA SLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFVGENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEVCRIYLLRIL HTYYKFDYKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDI QSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGK VWDLFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGY RKNEGYMRRGGYRQQQSQTAY hide sequence

RefSeq Acc Id:	XP_016879109 ⟸ XM_017023620
- Peptide Label:	isoform X2
- UniProtKB:	A1KYQ7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLI RTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVS AATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEEDNEGGEWERVRGGVPLVKEKPKMFA KGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQIAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFVGENILEESENLHNADQPLRVRGCILTL VERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYH HALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHES DARRRMISKQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEEL MVGAGVGSGQVEPWRDWSRGA hide sequence

Protein Domains

PCI

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B5ME19-F1-model_v2	AlphaFold	B5ME19	1-914	view protein structure

RGD ID:

7231701

Promoter ID:

EPDNEW_H21597

Type:

initiation region

Name:

EIF3CL_1

Description:

eukaryotic translation initiation factor 3 subunit C like

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	16	28,403,841 - 28,403,901	EPDNEW

Database	Acc Id	Source(s)
COSMIC	EIF3CL	COSMIC
Ensembl Genes	ENSG00000205609	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000380876	ENTREZGENE
	ENST00000380876.5	UniProtKB/Swiss-Prot
	ENST00000398944	ENTREZGENE
	ENST00000398944.7	UniProtKB/Swiss-Prot
Gene3D-CATH	1.10.10.10	UniProtKB/Swiss-Prot
GTEx	ENSG00000205609	GTEx
HGNC ID	HGNC:26347	ENTREZGENE
Human Proteome Map	EIF3CL	Human Proteome Map
InterPro	EIF3C	UniProtKB/Swiss-Prot
	EIF3C_N_dom	UniProtKB/Swiss-Prot
	PCI_dom	UniProtKB/Swiss-Prot
	WH-like_DNA-bd_sf	UniProtKB/Swiss-Prot
	WH_DNA-bd_sf	UniProtKB/Swiss-Prot
KEGG Report	hsa:728689	UniProtKB/Swiss-Prot
NCBI Gene	728689	ENTREZGENE
PANTHER	EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C-RELATED	UniProtKB/Swiss-Prot
	PTHR13937	UniProtKB/Swiss-Prot
Pfam	eIF-3c_N	UniProtKB/Swiss-Prot
	PCI	UniProtKB/Swiss-Prot
PharmGKB	PA162384693	PharmGKB
PROSITE	PCI	UniProtKB/Swiss-Prot
SMART	PINT	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF46785	UniProtKB/Swiss-Prot
UniProt	A1KYQ7	ENTREZGENE, UniProtKB/TrEMBL
	A8K7Z0	ENTREZGENE
	B2RXG3	ENTREZGENE
	B3KNZ4	ENTREZGENE, UniProtKB/TrEMBL
	B4E1D5	ENTREZGENE
	B5ME19	ENTREZGENE, UniProtKB/Swiss-Prot
	H3BRV0	ENTREZGENE
	O00215	ENTREZGENE
	Q99613	ENTREZGENE
	Q9BW98	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-04-14	EIF3CL	eukaryotic translation initiation factor 3 subunit C like	LOC112268171	uncharacterized LOC112268171	Data merged from RGD:38609111	737654	PROVISIONAL
2017-02-28	EIF3CL	eukaryotic translation initiation factor 3 subunit C like		eukaryotic translation initiation factor 3 subunit C-like	Symbol and/or name change	5135510	APPROVED
2015-12-08	EIF3CL	eukaryotic translation initiation factor 3 subunit C-like		eukaryotic translation initiation factor 3, subunit C-like	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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