LOC479795 (eukaryotic translation initiation factor 3 subunit C) - Rat Genome Database

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Gene: LOC479795 (eukaryotic translation initiation factor 3 subunit C) Canis lupus familiaris
Analyze
Symbol: LOC479795
Name: eukaryotic translation initiation factor 3 subunit C
RGD ID: 12139451
Description: ENCODES a protein that exhibits ribosome binding (ortholog); translation initiation factor activity (ortholog); INVOLVED IN positive regulation of translation (ortholog); ASSOCIATED WITH genetic disease (ortholog); neuronal ceroid lipofuscinosis (ortholog); schizophrenia (ortholog); FOUND IN eukaryotic translation initiation factor 3 complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: EIF3C; EIF3CL; EIF3S8; eukaryotic translation initiation factor 3, subunit 8, 110kDa
RGD Orthologs
Human
Bonobo
Pig
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1618,276,824 - 18,299,336 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,855,500 - 19,878,019 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0618,412,847 - 18,435,356 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1618,211,867 - 18,234,448 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0618,127,171 - 18,149,676 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0618,443,260 - 18,465,768 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC479795
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1618,276,824 - 18,299,336 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,855,500 - 19,878,019 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0618,412,847 - 18,435,356 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1618,211,867 - 18,234,448 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0618,127,171 - 18,149,676 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0618,443,260 - 18,465,768 (+)NCBIUU_Cfam_GSD_1.0
EIF3CL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381628,379,581 - 28,426,418 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1628,379,579 - 28,403,841 (-)EnsemblGRCh38hg38GRCh38
GRCh371628,390,902 - 28,415,206 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361628,298,401 - 28,322,663 (-)NCBINCBI36Build 36hg18NCBI36
Celera1628,059,153 - 28,083,429 (-)NCBICelera
Cytogenetic Map16p12.1NCBI
HuRef1626,450,046 - 26,474,307 (-)NCBIHuRef
CHM1_11629,404,042 - 29,426,909 (-)NCBICHM1_1
T2T-CHM13v2.01628,659,992 - 28,707,115 (-)NCBIT2T-CHM13v2.0
EIF3CL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21829,766,299 - 29,809,615 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11634,307,515 - 34,346,162 (-)NCBINHGRI_mPanPan1
LOC110260088
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1318,467,725 - 18,489,088 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1

Variants

.
Variants in LOC479795
305 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: XM_038478685   ⟹   XP_038334613
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1618,211,867 - 18,234,446 (+)NCBI
RefSeq Acc Id: XM_038478686   ⟹   XP_038334614
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1618,212,134 - 18,234,448 (+)NCBI
RefSeq Acc Id: XM_038539929   ⟹   XP_038395857
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0618,443,260 - 18,465,766 (+)NCBI
RefSeq Acc Id: XM_038539930   ⟹   XP_038395858
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0618,443,527 - 18,465,768 (+)NCBI
RefSeq Acc Id: XM_038543774   ⟹   XP_038399702
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha619,855,767 - 19,878,019 (+)NCBI
RefSeq Acc Id: XM_038604011   ⟹   XP_038459939
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0618,127,171 - 18,149,674 (+)NCBI
RefSeq Acc Id: XM_038604012   ⟹   XP_038459940
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0618,127,438 - 18,149,676 (+)NCBI
RefSeq Acc Id: XM_038668728   ⟹   XP_038524656
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0618,412,847 - 18,435,354 (+)NCBI
RefSeq Acc Id: XM_038668729   ⟹   XP_038524657
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0618,413,114 - 18,435,356 (+)NCBI
RefSeq Acc Id: XM_536923   ⟹   XP_536923
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1618,276,824 - 18,299,336 (+)NCBI
Dog10K_Boxer_Tasha619,855,500 - 19,878,017 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_536923   ⟸   XM_536923
- UniProtKB: A0A8C0KYR4 (UniProtKB/TrEMBL),   A0A8C0PM52 (UniProtKB/TrEMBL),   A0A8I3MQ25 (UniProtKB/TrEMBL),   A0A8C0LWF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038334613   ⟸   XM_038478685
RefSeq Acc Id: XP_038334614   ⟸   XM_038478686
RefSeq Acc Id: XP_038459939   ⟸   XM_038604011
RefSeq Acc Id: XP_038459940   ⟸   XM_038604012
RefSeq Acc Id: XP_038524656   ⟸   XM_038668728
- UniProtKB: A0A8C0KYR4 (UniProtKB/TrEMBL),   A0A8C0PM52 (UniProtKB/TrEMBL),   A0A8I3MQ25 (UniProtKB/TrEMBL),   A0A8C0LWF3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038524657   ⟸   XM_038668729
- UniProtKB: A0A8C0KYR4 (UniProtKB/TrEMBL),   A0A8C0PM52 (UniProtKB/TrEMBL),   A0A8I3MQ25 (UniProtKB/TrEMBL),   A0A8C0LWF3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038399702   ⟸   XM_038543774
- UniProtKB: A0A8C0KYR4 (UniProtKB/TrEMBL),   A0A8C0PM52 (UniProtKB/TrEMBL),   A0A8I3MQ25 (UniProtKB/TrEMBL),   A0A8C0LWF3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038395857   ⟸   XM_038539929
- UniProtKB: A0A8C0KYR4 (UniProtKB/TrEMBL),   A0A8C0LWF3 (UniProtKB/TrEMBL),   A0A8C0PM52 (UniProtKB/TrEMBL),   A0A8I3MQ25 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038395858   ⟸   XM_038539930
- UniProtKB: A0A8C0KYR4 (UniProtKB/TrEMBL),   A0A8C0LWF3 (UniProtKB/TrEMBL),   A0A8C0PM52 (UniProtKB/TrEMBL),   A0A8I3MQ25 (UniProtKB/TrEMBL)
Protein Domains
PCI


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017143 UniProtKB/TrEMBL
  ENSCAFG00030000322 UniProtKB/TrEMBL
  ENSCAFG00040000727 UniProtKB/TrEMBL
  ENSCAFG00845002564 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000027155.5 UniProtKB/TrEMBL
  ENSCAFT00000092948.2 UniProtKB/TrEMBL
  ENSCAFT00030000527.1 UniProtKB/TrEMBL
  ENSCAFT00040001335.1 UniProtKB/TrEMBL
  ENSCAFT00040001373.1 UniProtKB/TrEMBL
  ENSCAFT00845004543 ENTREZGENE
  ENSCAFT00845004543.1 UniProtKB/TrEMBL
  ENSCAFT00845004589 ENTREZGENE
  ENSCAFT00845004589.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro EIF3C UniProtKB/TrEMBL
  EIF3C_N_dom UniProtKB/TrEMBL
  PCI_dom UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene LOC479795 ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C-RELATED UniProtKB/TrEMBL
  PTHR13937 UniProtKB/TrEMBL
Pfam eIF-3c_N UniProtKB/TrEMBL
  PCI UniProtKB/TrEMBL
PROSITE PCI UniProtKB/TrEMBL
SMART PINT UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt A0A8C0KYR4 ENTREZGENE
  A0A8C0LWF3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PM52 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PRH5_CANLF UniProtKB/TrEMBL
  A0A8I3MQ25 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RSA1_CANLF UniProtKB/TrEMBL