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Gene: Cpa4 (carboxypeptidase A4) Mus musculus

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Symbol:

Cpa4

Name:

carboxypeptidase A4

RGD ID:

1622267

MGI Page

MGI

Description:

Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in hormone catabolic process; peptide catabolic process; and proteolysis. Predicted to be active in extracellular space. Orthologous to human CPA4 (carboxypeptidase A4).

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

1110019K20Rik; AV009555

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CPA4 (carboxypeptidase A4)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Cpa4 (carboxypeptidase A4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cpa4 (carboxypeptidase A4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CPA4 (carboxypeptidase A4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CPA4 (carboxypeptidase A4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cpa4 (carboxypeptidase A4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CPA4 (carboxypeptidase A4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CPA4 (carboxypeptidase A4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cpa4 (carboxypeptidase A4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CPA4 (carboxypeptidase A4)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	Cpa4 (carboxypeptidase A4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cpa4 (carboxypeptidase A4)	Alliance	DIOPT (OMA\|OrthoInspector\|PANTHER\|ZFIN)
Drosophila melanogaster (fruit fly):	CG4408	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG7025	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ECM14	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	T06A4.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG18585	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG4017	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG14820	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG17633	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG2915	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG3097	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA)
Caenorhabditis elegans (roundworm):	Y18H1A.9	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Caenorhabditis elegans (roundworm):	T06A4.3	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|SonicParanoid)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	30,568,368 - 30,592,417 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	30,568,368 - 30,592,417 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	30,568,369 - 30,592,418 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	30,568,369 - 30,592,418 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	30,518,376 - 30,541,747 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	30,518,386 - 30,541,757 (+)	NCBI		MGSCv36	mm8
Celera	6	30,578,234 - 30,601,732 (+)	NCBI		Celera
Cytogenetic Map	6	A3.3	NCBI
cM Map	6	12.52	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Cpa4	Mouse	pleomorphic xanthoastrocytoma		ISO	CPA4 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Pleomorphic xanthoastrocytoma	ClinVar	PMID:28299358

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Cpa4	Mouse	17beta-estradiol	multiple interactions	ISO	CPA4 (Homo sapiens)	6480464	[Estradiol co-treated with TGFB1 protein] results in decreased expression of CPA4 mRNA	CTD	PMID:30165855
Cpa4	Mouse	17beta-estradiol	decreases expression	ISO	Cpa4 (Rattus norvegicus)	6480464	Estradiol results in decreased expression of CPA4 mRNA	CTD	PMID:35192832
Cpa4	Mouse	2,2',5,5'-tetrachlorobiphenyl	decreases expression	ISO	CPA4 (Homo sapiens)	6480464	2 more ...	CTD	PMID:36804509
Cpa4	Mouse	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	ISO	Cpa4 (Rattus norvegicus)	6480464	Tetrachlorodibenzodioxin results in decreased expression of CPA4 mRNA	CTD	PMID:32277265
Cpa4	Mouse	2-hydroxypropanoic acid	decreases expression	ISO	CPA4 (Homo sapiens)	6480464	Lactic Acid results in decreased expression of CPA4 mRNA	CTD	PMID:30851411
Cpa4	Mouse	5-fluorouracil	decreases expression	ISO	CPA4 (Homo sapiens)	6480464	Fluorouracil results in decreased expression of CPA4 mRNA	CTD	PMID:16510598
Cpa4	Mouse	acrylamide	increases expression	ISO	Cpa4 (Rattus norvegicus)	6480464	Acrylamide results in increased expression of CPA4 mRNA	CTD	PMID:28959563
Cpa4	Mouse	actinomycin D	multiple interactions	ISO	CPA4 (Homo sapiens)	6480464	[Dactinomycin co-treated with nutlin 3] results in increased secretion of CPA4 protein	CTD	PMID:38460933
Cpa4	Mouse	aflatoxin B1	increases expression	ISO	CPA4 (Homo sapiens)	6480464	Aflatoxin B1 results in increased expression of CPA4 mRNA	CTD	PMID:22100608
Cpa4	Mouse	all-trans-retinoic acid	decreases expression	ISO	CPA4 (Homo sapiens)	6480464	Tretinoin results in decreased expression of CPA4 mRNA	CTD	PMID:23830798
Cpa4	Mouse	Archazolid B	increases expression	ISO	CPA4 (Homo sapiens)	6480464	archazolid B results in increased expression of CPA4 mRNA	CTD	PMID:25218289
Cpa4	Mouse	aristolochic acid A	increases expression	ISO	CPA4 (Homo sapiens)	6480464	aristolochic acid I results in increased expression of CPA4 mRNA	CTD	PMID:33212167
Cpa4	Mouse	arsane	multiple interactions	ISO	CPA4 (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of CPA4 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of CPA4 mRNA	CTD	PMID:39836092
Cpa4	Mouse	arsenic atom	multiple interactions	ISO	CPA4 (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of CPA4 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of CPA4 mRNA	CTD	PMID:39836092
Cpa4	Mouse	arsenite(3-)	decreases expression	ISO	CPA4 (Homo sapiens)	6480464	arsenite results in decreased expression of CPA4 mRNA	CTD	PMID:23974009
Cpa4	Mouse	atrazine	affects methylation	ISO	Cpa4 (Rattus norvegicus)	6480464	Atrazine affects the methylation of CPA4 gene	CTD	PMID:35440735
Cpa4	Mouse	benzo[a]pyrene	decreases expression	EXP		6480464	Benzo(a)pyrene results in decreased expression of CPA4 mRNA	CTD	PMID:22228805
Cpa4	Mouse	benzo[a]pyrene	increases expression	ISO	CPA4 (Homo sapiens)	6480464	Benzo(a)pyrene results in increased expression of CPA4 mRNA	CTD	PMID:32234424
Cpa4	Mouse	benzo[a]pyrene	decreases methylation	ISO	CPA4 (Homo sapiens)	6480464	Benzo(a)pyrene results in decreased methylation of CPA4 3' UTR	CTD	PMID:27901495
Cpa4	Mouse	benzo[a]pyrene diol epoxide I	increases expression	ISO	CPA4 (Homo sapiens)	6480464	7 more ...	CTD	PMID:20382639
Cpa4	Mouse	bis(2-chloroethyl) sulfide	increases expression	ISO	CPA4 (Homo sapiens)	6480464	Mustard Gas results in increased expression of CPA4 mRNA	CTD	PMID:25102026
Cpa4	Mouse	bisphenol A	decreases expression	ISO	Cpa4 (Rattus norvegicus)	6480464	bisphenol A results in decreased expression of CPA4 mRNA	CTD	PMID:25181051 more ...
Cpa4	Mouse	bisphenol A	decreases expression	ISO	CPA4 (Homo sapiens)	6480464	bisphenol A results in decreased expression of CPA4 mRNA and bisphenol A results in decreased expression of CPA4 protein	CTD	PMID:29275510 and PMID:32981897
Cpa4	Mouse	bisphenol A	increases expression	ISO	CPA4 (Homo sapiens)	6480464	bisphenol A results in increased expression of CPA4 mRNA	CTD	PMID:27685785
Cpa4	Mouse	butan-1-ol	multiple interactions	ISO	CPA4 (Homo sapiens)	6480464	[[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of CPA4 mRNA	CTD	PMID:29432896
Cpa4	Mouse	butanal	increases expression	ISO	CPA4 (Homo sapiens)	6480464	butyraldehyde results in increased expression of CPA4 mRNA	CTD	PMID:26079696
Cpa4	Mouse	cadmium atom	affects expression	ISO	CPA4 (Homo sapiens)	6480464	Cadmium affects the expression of CPA4 mRNA	CTD	PMID:31082282
Cpa4	Mouse	cadmium atom	increases expression	ISO	CPA4 (Homo sapiens)	6480464	Cadmium results in increased expression of CPA4 mRNA	CTD	PMID:35955783
Cpa4	Mouse	cadmium dichloride	increases expression	ISO	CPA4 (Homo sapiens)	6480464	Cadmium Chloride results in increased expression of CPA4 mRNA	CTD	PMID:38382870 and PMID:38568856
Cpa4	Mouse	calcitriol	decreases expression	ISO	CPA4 (Homo sapiens)	6480464	Calcitriol results in decreased expression of CPA4 mRNA	CTD	PMID:16002434
Cpa4	Mouse	camptothecin	increases expression	ISO	CPA4 (Homo sapiens)	6480464	Camptothecin results in increased expression of CPA4 mRNA	CTD	PMID:38460933
Cpa4	Mouse	CGP 52608	multiple interactions	ISO	CPA4 (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to CPA4 gene]	CTD	PMID:28238834
Cpa4	Mouse	cisplatin	multiple interactions	ISO	CPA4 (Homo sapiens)	6480464	[Cisplatin co-treated with jinfukang] results in increased expression of CPA4 mRNA	CTD	PMID:27392435
Cpa4	Mouse	cisplatin	increases expression	ISO	CPA4 (Homo sapiens)	6480464	Cisplatin results in increased expression of CPA4 mRNA	CTD	PMID:27392435
Cpa4	Mouse	cobalt dichloride	decreases secretion	ISO	CPA4 (Homo sapiens)	6480464	cobaltous chloride results in decreased secretion of CPA4 protein	CTD	PMID:22079246
Cpa4	Mouse	copper atom	multiple interactions	ISO	CPA4 (Homo sapiens)	6480464	[NSC 689534 binds to Copper] which results in increased expression of CPA4 mRNA	CTD	PMID:20971185
Cpa4	Mouse	copper(0)	multiple interactions	ISO	CPA4 (Homo sapiens)	6480464	[NSC 689534 binds to Copper] which results in increased expression of CPA4 mRNA	CTD	PMID:20971185
Cpa4	Mouse	cyclosporin A	decreases expression	ISO	CPA4 (Homo sapiens)	6480464	Cyclosporine results in decreased expression of CPA4 mRNA	CTD	PMID:27989131
Cpa4	Mouse	Didecyldimethylammonium	decreases expression	ISO	CPA4 (Homo sapiens)	6480464	didecyldimethylammonium results in decreased expression of CPA4 mRNA	CTD	PMID:32763356
Cpa4	Mouse	diethylstilbestrol	increases expression	ISO	CPA4 (Homo sapiens)	6480464	Diethylstilbestrol results in increased expression of CPA4 mRNA	CTD	PMID:36621641
Cpa4	Mouse	ethanol	multiple interactions	ISO	CPA4 (Homo sapiens)	6480464	[[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of CPA4 mRNA	CTD	PMID:29432896
Cpa4	Mouse	hydrogen peroxide	increases expression	ISO	CPA4 (Homo sapiens)	6480464	Hydrogen Peroxide results in increased expression of CPA4 mRNA	CTD	PMID:32949572
Cpa4	Mouse	isobutanol	multiple interactions	ISO	CPA4 (Homo sapiens)	6480464	[[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of CPA4 mRNA	CTD	PMID:29432896
Cpa4	Mouse	lipopolysaccharide	multiple interactions	ISO	CPA4 (Homo sapiens)	6480464	[S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of CPA4 mRNA	CTD	PMID:35811015
Cpa4	Mouse	manganese atom	multiple interactions	ISO	CPA4 (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of CPA4 mRNA	CTD	PMID:39836092
Cpa4	Mouse	manganese(0)	multiple interactions	ISO	CPA4 (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of CPA4 mRNA	CTD	PMID:39836092
Cpa4	Mouse	manganese(II) chloride	multiple interactions	ISO	CPA4 (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of CPA4 mRNA	CTD	PMID:39836092
Cpa4	Mouse	mono(2-ethylhexyl) phthalate	decreases expression	ISO	CPA4 (Homo sapiens)	6480464	mono-(2-ethylhexyl)phthalate results in decreased expression of CPA4 mRNA	CTD	PMID:36695872
Cpa4	Mouse	N,N-diethyl-m-toluamide	multiple interactions	ISO	Cpa4 (Rattus norvegicus)	6480464	[Permethrin co-treated with DEET] results in decreased methylation of CPA4 gene	CTD	PMID:33148267
Cpa4	Mouse	Nutlin-3	multiple interactions	ISO	CPA4 (Homo sapiens)	6480464	[Dactinomycin co-treated with nutlin 3] results in increased secretion of CPA4 protein	CTD	PMID:38460933
Cpa4	Mouse	O-methyleugenol	increases expression	ISO	CPA4 (Homo sapiens)	6480464	methyleugenol results in increased expression of CPA4 mRNA	CTD	PMID:32234424
Cpa4	Mouse	okadaic acid	increases expression	ISO	CPA4 (Homo sapiens)	6480464	Okadaic Acid results in increased expression of CPA4 mRNA	CTD	PMID:38832940
Cpa4	Mouse	palbociclib	increases expression	ISO	CPA4 (Homo sapiens)	6480464	palbociclib results in increased expression of CPA4 mRNA	CTD	PMID:22869556
Cpa4	Mouse	paracetamol	increases expression	ISO	CPA4 (Homo sapiens)	6480464	Acetaminophen results in increased expression of CPA4 mRNA	CTD	PMID:29067470
Cpa4	Mouse	paraquat	increases expression	ISO	Cpa4 (Rattus norvegicus)	6480464	Paraquat results in increased expression of CPA4 mRNA	CTD	PMID:32680482
Cpa4	Mouse	pentanal	increases expression	ISO	CPA4 (Homo sapiens)	6480464	pentanal results in increased expression of CPA4 mRNA	CTD	PMID:26079696
Cpa4	Mouse	permethrin	multiple interactions	ISO	Cpa4 (Rattus norvegicus)	6480464	[Permethrin co-treated with DEET] results in decreased methylation of CPA4 gene	CTD	PMID:33148267
Cpa4	Mouse	propanal	increases expression	ISO	CPA4 (Homo sapiens)	6480464	propionaldehyde results in increased expression of CPA4 mRNA	CTD	PMID:26079696
Cpa4	Mouse	rac-lactic acid	decreases expression	ISO	CPA4 (Homo sapiens)	6480464	Lactic Acid results in decreased expression of CPA4 mRNA	CTD	PMID:30851411
Cpa4	Mouse	S-(1,2-dichlorovinyl)-L-cysteine	multiple interactions	ISO	CPA4 (Homo sapiens)	6480464	[S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of CPA4 mRNA	CTD	PMID:35811015
Cpa4	Mouse	silicon dioxide	increases expression	ISO	CPA4 (Homo sapiens)	6480464	Silicon Dioxide analog results in increased expression of CPA4 mRNA	CTD	PMID:25895662
Cpa4	Mouse	silicon dioxide	decreases expression	ISO	CPA4 (Homo sapiens)	6480464	Silicon Dioxide analog results in decreased expression of CPA4 mRNA	CTD	PMID:23806026
Cpa4	Mouse	sodium arsenite	decreases expression	ISO	CPA4 (Homo sapiens)	6480464	sodium arsenite results in decreased expression of CPA4 mRNA	CTD	PMID:35954277 and PMID:38568856
Cpa4	Mouse	sodium arsenite	decreases expression	EXP		6480464	sodium arsenite results in decreased expression of CPA4 mRNA	CTD	PMID:36209798
Cpa4	Mouse	sodium arsenite	multiple interactions	ISO	CPA4 (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of CPA4 mRNA more ...	CTD	PMID:33939924 and PMID:39836092
Cpa4	Mouse	succimer	multiple interactions	ISO	CPA4 (Homo sapiens)	6480464	[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of CPA4 mRNA	CTD	PMID:26378955
Cpa4	Mouse	sulforaphane	decreases expression	ISO	CPA4 (Homo sapiens)	6480464	sulforaphane results in decreased expression of CPA4 mRNA	CTD	PMID:31838189
Cpa4	Mouse	sunitinib	decreases expression	ISO	CPA4 (Homo sapiens)	6480464	Sunitinib results in decreased expression of CPA4 mRNA	CTD	PMID:31533062
Cpa4	Mouse	triclosan	decreases expression	ISO	CPA4 (Homo sapiens)	6480464	Triclosan results in decreased expression of CPA4 mRNA	CTD	PMID:30510588
Cpa4	Mouse	tunicamycin	increases expression	EXP		6480464	Tunicamycin results in increased expression of CPA4 mRNA	CTD	PMID:17127020
Cpa4	Mouse	valproic acid	increases expression	ISO	CPA4 (Homo sapiens)	6480464	Valproic Acid results in increased expression of CPA4 mRNA	CTD	PMID:28001369
Cpa4	Mouse	zoledronic acid	decreases expression	ISO	CPA4 (Homo sapiens)	6480464	zoledronic acid results in decreased expression of CPA4 mRNA	CTD	PMID:24714768

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Cpa4	Mouse	hormone catabolic process	involved_in	ISS	UniProtKB:Q9UI42	2290270		UniProt	GO_REF:0000024
Cpa4	Mouse	hormone catabolic process	involved_in	ISO	UniProtKB:Q9UI42	2290270		GO_Central	GO_REF:0000119
Cpa4	Mouse	peptide catabolic process	involved_in	ISO	UniProtKB:Q9UI42	2290270		GO_Central	GO_REF:0000119
Cpa4	Mouse	peptide catabolic process	involved_in	ISS	UniProtKB:Q9UI42	2290270		UniProt	GO_REF:0000024
Cpa4	Mouse	proteolysis	involved_in	IBA	PANTHER:PTN000194073 more ...	2290270		GO_Central	GO_REF:0000033
Cpa4	Mouse	proteolysis	involved_in	IEA	UniProtKB-KW:KW-0645	2290270		UniProt	GO_REF:0000043

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Cpa4	Mouse	extracellular space	is_active_in	IBA	PANTHER:PTN000194073 more ...	2290270		GO_Central	GO_REF:0000033
Cpa4	Mouse	extracellular space	located_in	ISS	UniProtKB:Q9UI42	2290270		UniProt	GO_REF:0000024
Cpa4	Mouse	extracellular space	located_in	ISO	UniProtKB:Q9UI42	2290270		GO_Central	GO_REF:0000119

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Cpa4	Mouse	metallocarboxypeptidase activity	enables	ISS	UniProtKB:Q9UI42	2290270		UniProt	GO_REF:0000024
Cpa4	Mouse	metallocarboxypeptidase activity	enables	ISO	UniProtKB:Q9UI42	2290270		GO_Central	GO_REF:0000119
Cpa4	Mouse	metallocarboxypeptidase activity	enables	IBA	PANTHER:PTN000194073 more ...	2290270		GO_Central	GO_REF:0000033
Cpa4	Mouse	protein binding	enables	ISO	UniProtKB:P84875	9068941	PMID:23746805	IntAct	PMID:23746805
Cpa4	Mouse	zinc ion binding	enables	IEA	InterPro:IPR000834	2290270		InterPro	GO_REF:0000002

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:10349636	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12466851	PMID:12477932	PMID:12921743	PMID:15489334	PMID:16141072	PMID:16141073	PMID:20385563	PMID:20562862
PMID:21267068	PMID:21677750	PMID:21873635	PMID:23892084	PMID:32347291

Cpa4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	30,568,368 - 30,592,417 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	30,568,368 - 30,592,417 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	30,568,369 - 30,592,418 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	30,568,369 - 30,592,418 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	30,518,376 - 30,541,747 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	30,518,386 - 30,541,757 (+)	NCBI		MGSCv36	mm8
Celera	6	30,578,234 - 30,601,732 (+)	NCBI		Celera
Cytogenetic Map	6	A3.3	NCBI
cM Map	6	12.52	NCBI

CPA4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	130,293,161 - 130,324,180 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	130,293,134 - 130,324,180 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	129,933,001 - 129,964,020 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	129,720,230 - 129,751,250 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	7	129,526,964 - 129,557,968	NCBI
Celera	7	124,728,740 - 124,759,787 (+)	NCBI		Celera
Cytogenetic Map	7	q32.2	NCBI
HuRef	7	124,295,376 - 124,326,433 (+)	NCBI		HuRef
CHM1_1	7	129,866,434 - 129,897,482 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	7	131,606,545 - 131,637,922 (+)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	129,318,357 - 129,349,405 (+)	NCBI

Cpa4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	60,155,675 - 60,179,644 (+)	NCBI		GRCr8
mRatBN7.2	4	59,188,284 - 59,212,255 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	59,188,284 - 59,212,255 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	64,166,435 - 64,190,319 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	60,082,621 - 60,106,503 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	58,484,547 - 58,508,431 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	57,883,849 - 57,907,826 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	57,883,849 - 57,907,826 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	57,644,770 - 57,668,743 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	57,479,967 - 57,503,748 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	54,286,758 - 54,310,882 (+)	NCBI		Celera
Cytogenetic Map	4	q22	NCBI

Cpa4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955479	10,940,215 - 10,966,081 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955479	10,940,269 - 10,963,629 (+)	NCBI	ChiLan1.0	ChiLan1.0

CPA4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	167,114,272 - 167,146,577 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	19,124,536 - 19,155,770 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	122,266,946 - 122,289,742 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	134,776,768 - 134,807,678 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	134,776,768 - 134,807,678 (+)	Ensembl	panpan1.1		panPan2

CPA4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	14	6,613,878 - 6,642,833 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	14	6,621,039 - 6,642,793 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	14	6,301,778 - 6,328,836 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	14	6,376,095 - 6,403,156 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	14	6,381,873 - 6,403,090 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	14	6,581,072 - 6,608,656 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	14	6,326,280 - 6,353,327 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	14	6,469,905 - 6,496,964 (-)	NCBI		UU_Cfam_GSD_1.0

Cpa4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	24,818,561 - 24,840,243 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936579	4,952,365 - 4,972,837 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936579	4,952,235 - 4,972,842 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CPA4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	18,530,867 - 18,553,634 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	18,528,998 - 18,553,944 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	19,395,015 - 19,408,487 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CPA4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	98,924,054 - 98,979,674 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	98,924,100 - 98,955,260 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666042	4,448,540 - 4,479,752 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cpa4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624783	5,976,691 - 5,999,815 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624783	5,976,784 - 5,999,366 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Cpa4
1139 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	473
Count of miRNA genes:	326
Interacting mature miRNAs:	368
Transcripts:	ENSMUST00000049251
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4142271	Egq8_m	early growth QTL 8 (mouse)			Not determined			4503823	96633110	Mouse
4140989	Spqq2_m	sperm quality QTL 2 (mouse)			Not determined			17711598	51711719	Mouse
26884441	Sklq3_m	skull length QTL 3, 5 week (mouse)					6	7600000	80576983	Mouse
1357520	Axtq2_m	anxiety QTL 2 (mouse)			Not determined		6	4503823	48703611	Mouse
10043869	Cia6a_m	collagen induced arthritis QTL 6a (mouse)			Not determined		6	12117971	46118069	Mouse
1301850	Fglu_m	fasting glucose (mouse)			Not determined		6	17711598	51711719	Mouse
4141749	Obrq2_m	obesity resistance QTL 2 (mouse)			Not determined			12751221	46751333	Mouse
1301724	Pcd4ts1_m	p-glycoprotein positive CD4 T cell subset 1 (mouse)			Not determined		6	17711598	51711719	Mouse
4142126	W3q3_m	weight 3 weeks QTL 3 (mouse)			Not determined			4503823	96633110	Mouse
10412107	Desp4_m	despair 4 (mouse)			Not determined		6	20049830	54049830	Mouse
1357442	Dbts1_m	diabetes 1 (mouse)			Not determined		6	18234147	73364675	Mouse
1301131	Chol2_m	cholesterol 2 (mouse)			Not determined		6	1	32144495	Mouse
1302024	Skull7_m	skull morphology 7 (mouse)			Not determined		6	1	32144495	Mouse
4141988	Obrq3_m	obesity resistance QTL 3 (mouse)			Not determined			28290993	62291115	Mouse
11353841	Bmiq3_m	body mass index QTL 3 (mouse)					6	4503823	48703611	Mouse
11353840	Bmiq2_m	body mass index QTL 2 (mouse)					6	4503823	45291115	Mouse
1300556	Cia6_m	collagen induced arthritis QTL 6 (mouse)			Not determined		6	4464884	87403016	Mouse
5491191	Mobq2_m	multigenic obesity QTL 2 (mouse)			Not determined		6	1	32144495	Mouse
25440480	Moaq2_m	modifier of alien QTL 2 (mouse)					6	3050001	117476961	Mouse
26884414	Bzwq12_m	bi-zygomatic width QTL 12, 16 week (mouse)					6	3400000	139076998	Mouse
4142361	W10q11_m	weight 10 weeks QTL 11 (mouse)			Not determined			4503823	96633110	Mouse
4142232	W6q4_m	weight 6 weeks QTL 4 (mouse)			Not determined			4503823	96633110	Mouse
1300731	Smdq3_m	segregation of mitochondrial DNA QTL 3 (mouse)			Not determined		6	4249206	38249325	Mouse
12904940	Edlmmq5_m	extensor digitorum longus muscle mass QTL 5 (mouse)					6	19616346	53616346	Mouse
15039372	Nmrs22_m	NAFLD-associated magnetic resonance shift 22 (mouse)					6	1476334	35476334	Mouse
12904943	Tammq4_m	tibialis anterior muscle mass QTL 4 (mouse)					6	19616346	53616346	Mouse
10412213	Sxbq2_m	SGC/Knj cross B6 QTL 2 (mouse)			Not determined		6	19912685	71299759	Mouse
1302051	Sluc7_m	susceptibility to lung cancer 7 (mouse)			Not determined		6	9297074	43297168	Mouse
14700690	Ccs6_m	colon cancer susceptibility 6 (mouse)					6	23776934	57776934	Mouse
27226726	Tibmd7_m	tibia midshaft diameter 7, 16 week (mouse)					6	17699999	53476985	Mouse
12904952	Gmmq4_m	gastrocnemius muscle mass QTL 4 (mouse)					6	19616346	53616346	Mouse
1357481	Aaj2_m	anxiety in A/J 2 (mouse)			Not determined		6	4503823	48703611	Mouse
1301998	Bts2_m	bladder tumor susceptibility 2 (mouse)			Not determined		6	12751221	46751333	Mouse
13208564	Bmiq7_m	body mass index QTL 7 (mouse)					6	24999999	79976983	Mouse

AV009555

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	30,592,166 - 30,592,268	UniSTS	GRCm38
MGSCv37	6	30,542,166 - 30,542,268	UniSTS	GRCm37
Celera	6	30,602,151 - 30,602,253	UniSTS
Cytogenetic Map	6	A3.3	UniSTS
Whitehead/MRC_RH	6	222.13	UniSTS

Cpa4

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	6	A3.3	UniSTS
cM Map	6		UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	NM_027926	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017321750	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC155656	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK003823	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK030705	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC061206	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466533	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000049251 ⟹ ENSMUSP00000048558

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	30,568,368 - 30,592,417 (+)	Ensembl
GRCm38.p6 Ensembl	6	30,568,369 - 30,592,418 (+)	Ensembl

RefSeq Acc Id:

NM_027926 ⟹ NP_082202

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	30,568,368 - 30,592,416 (+)	NCBI
GRCm38	6	30,568,369 - 30,592,417 (+)	NCBI
MGSCv37	6	30,518,376 - 30,541,747 (+)	RGD
Celera	6	30,578,234 - 30,601,732 (+)	RGD
cM Map	6		ENTREZGENE

Sequence:

show sequence

AGTATGTGACTGGCGCCCTTGAGACATGAAGTGGCTACTGTTCTTTGGGGCCCTGATTGGGGCAGGCATCTGCGGCCGAGATAAATTCTTTGGGGACCAAGTTTTTAGGATTAATGTCAGAAATGGAG
ACGAGATCAGAAAACTGACTGAGCTAGTGAATTCTGACCACTTAAAGCTCAGTGTCTGGAAATCTCCCTCCACTTTTGATCGGCCCGTGGATATTCTCGTCCCTTCTGTCAGCTTGCTCCCAGTCAAG
TCCTTCCTGAAGTCCCAGGGTTTAGACTACTCCGTGACAATTGAGGACCTCCAGGCCCTTTTAGATAACGAAGATGAAGAAATGCAGCACAATGAAGGGATAGAGCGGAGTGGTGACTTCAACTACGG
AGCTTACCATCCCCTGGAGGCTATTTACCACGAGATGGACAGTATTGCCACAGACTTTCCTGAGCTGGTGAGCAGAGTGAAGATTGGAGAGACATTTGAAAAGCGGCCCATGTATGTTCTAAAGTTCA
GCACGGGAGGAGGCAAGAAGCGGCCAGCCATTTGGTTGAATGCAGGCATCCATGCCCGTGAGTGGATCTCACAGGCCACAGCCATCTGGACAGCGAGGAAGATTGTAACTGATTATAAAAAGGACCCG
GCTATCACCTCCATCTTGAAGAAAGTGGATATTTTCTTGTTGCCCGTGGCCAATCCTGATGGATATGTGTACACGCAAAGCCAGAACCGATTATGGAGAAAGACGCGGTCCCGGAACCCAGGAAGCCG
CTGTGTTGGAGCCGATCCAAACAGAAACTGGAATGCTAGTTTTGCAGGAGAGGGGACCAGTGATAACCCTTGCTCTGAAGTGTACCATGGCTCCCACCCCAATTCTGAAGTGGAGGTGAAATCGGTGG
TGGATTTCATTCAAAAGCATGGGAACTTCAAATGCTTCATTGACCTGCATAGCTACTCACAGCTGCTGATGTATCCCTATGGGTACACAGTCAAGAAGGCCCCGGATGCTGAGGAGCTGGACGATGTG
GCGAGGAATGCAGCCCAAGCCCTGGCTTCTCTCTCGGGCACTAAGTACCGAGTGGGCCCAACTTGCACCACCGTCTATCCAGCTAGTGGGAGCAGCGTTGACTGGGCATACGACAATGGCATCAAGTA
TGCTTTCACATTTGAGCTGAGAGACACTGGGTACTACGGCTTCCTCTTGCCAGCCAGCCAGATCATCCCCACCGCGGAGGAGACCTGGCTAGGGCTGAAGACCATCATGGAACATGTTCGGGACCACC
TCTACTAGTCAAAGAACACTTACATTTTACCTCTAAGCCACCACTTAGTTTAACATCACTTCTTCACGGATAGGTCGGAGCCTTCTGAGTCGGCAGAGAACTCAGCTGCCTCCTCTTCAGCATCGCTT
CACAGAGATCACACCTCCTGGTAGTGAGCACGTGAGGGACACTTCTTCCGTGGAGTGGTCGGTCCCGCTGCTCTACTGACCTTTGGTGTATATACCTCTCTATTCACGCAGCTGGTTAGGCGGGCCAC
AGAGGTCATGACTTCCTGGTGGCCTATGGCTACCTCACCTTTAGAACTTTGATGGTCCTCTAGTCTTTACCTGTAGCCTTGGGTAGGGCACCATGGGAGGTGCCAGGGGAGACAGTGCCTGTCTTCAG
AACTCTGTAATTTCTCCTTCAAACATGTTCTCTCTTTTTATTTATTTATTTTTTCTTTTAGACAGGGTCTTACTATTTTGCCCATGCTAGCCTGAAGCTCCTGGGGTCAAACTGTACCCTTCCCCGCC
TCCTCCTTGCCCCATCTTCCCAGTAGTGGTATGCAGCTCAGGAACACACTTTTCTTTGAGGAAACAAATCCTATTAGACCATCATCATTGCTCTTTCTAGCTGCGTATTCTTCCTATTCCTCCTCCTC
CTCCTCCTCATCATCATCATCATGGAGACAGGATCTCTTTATGTAGCCATGACTGTCCTGGAGCTTGCTATATAGACCAAGCTGGCCTTGAACTTACAGAGATCTGCCTGGCTCTGCCTTCAGCATAC
ATTAAAGATGTATTATCACCATACCTGGCTCATCTTAATTCTTTTCTGTTGGCTCGAGCACACAGTCAAGCTCTTGTCCATTACAAGGCTCAGTGTTCAGGTGATGCCCTTTGCTTTTTAAACCGTCT
TTTCTTTATATGTGGTGTTACTGGGATCCTCTAAGAGGGTCAGTTAGTTATGTTGTAGGCAAGGCTCTCAGGGGTCATGGGGAAACGGGGCTAGATTGCAGGGACAGATTAGCACCATCTGTCCTCTT
GGCCTCACCACCACTCTGCCTTTTGAACTCACTTCAAAGATTTTGACCTCACCCCACAGGTCCTAAATCATCCCTAGAGCCTGGATAATCTCAGGGCCTCAGCACACTCCAGCTCCGGCTCTGGTGTG
CCCTGCGTTTCAGGCTCCTGGTTTCTGTCCTCCTGTGTTTAATGTTACTTTCTATTTTGCATCCTGAACCCTGAGTACCTACCTGAAACAAGACTTCGTCAACAGCTAGACACTTCCTGTTCTCTCCT
TAGCACATACTGTCTGCCCTGTTTGTGTTGTGGTTTTTGTGTTTTTGTTTTCTTGTGGGTATTTTTTTTTTTCTTTTTCTGTTTTCAATCATGTCTATAAATCTTAACCTTCTGCCTAGGATTTGGGC
AGCATCTGGTGTGTCCTCATAAGCCAATAAATATTCAATATGGGTCTCCT

hide sequence

RefSeq Acc Id:

XM_017321750 ⟹ XP_017177239

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	30,568,393 - 30,592,417 (+)	NCBI
GRCm38	6	30,568,394 - 30,592,418 (+)	NCBI

Sequence:

show sequence

ATGAAGTGGCTACTGTTCTTTGGGGCCCTGATTGGGGCAGGCATCTGCGGCCGAGATAAATTCT
TTGGGTCCTTCAGCCCACATCCCTCTCCAGCAGCTCCTCCGACTAGACCATTTCCTCTCATCCTATCCAGCTCTGTCTGGGATGGTGGGTTTGGGGGTCTACTTGCCAGCAGAAAGCTCACCATTATC
TTCTTCTCCCTCCCCTTCTCCAGGGACCAAGTTTTTAGGATTAATGTCAGAAATGGAGACGAGATCAGAAAACTGACTGAGCTAGTGAATTCTGACCACTTAAAGCTCAGTGTCTGGAAATCTCCCTC
CACTTTTGATCGGCCCGTGGATATTCTCGTCCCTTCTGTCAGCTTGCTCCCAGTCAAGTCCTTCCTGAAGTCCCAGGGTTTAGACTACTCCGTGACAATTGAGGACCTCCAGGCCCTTTTAGATAACG
AAGATGAAGAAATGCAGCACAATGAAGGGATAGAGCGGAGTGGTGACTTCAACTACGGAGCTTACCATCCCCTGGAGGCTATTTACCACGAGATGGACAGTATTGCCACAGACTTTCCTGAGCTGGTG
AGCAGAGTGAAGATTGGAGAGACATTTGAAAAGCGGCCCATGTATGTTCTAAAGTTCAGCACGGGAGGAGGCAAGAAGCGGCCAGCCATTTGGTTGAATGCAGGCATCCATGCCCGTGAGTGGATCTC
ACAGGCCACAGCCATCTGGACAGCGAGGAAGATTGTAACTGATTATAAAAAGGACCCGGCTATCACCTCCATCTTGAAGAAAGTGGATATTTTCTTGTTGCCCGTGGCCAATCCTGATGGATATGTGT
ACACGCAAAGCCAGAACCGATTATGGAGAAAGACGCGGTCCCGGAACCCAGGAAGCCGCTGTGTTGGAGCCGATCCAAACAGAAACTGGAATGCTAGTTTTGCAGGAGAGGGGACCAGTGATAACCCT
TGCTCTGAAGTGTACCATGGCTCCCACCCCAATTCTGAAGTGGAGGTGAAATCGGTGGTGGATTTCATTCAAAAGCATGGGAACTTCAAATGCTTCATTGACCTGCATAGCTACTCACAGCTGCTGAT
GTATCCCTATGGGTACACAGTCAAGAAGGCCCCGGATGCTGAGGAGCTGGACGATGTGGCGAGGAATGCAGCCCAAGCCCTGGCTTCTCTCTCGGGCACTAAGTACCGAGTGGGCCCAACTTGCACCA
CCGTCTATCCAGCTAGTGGGAGCAGCGTTGACTGGGCATACGACAATGGCATCAAGTATGCTTTCACATTTGAGCTGAGAGACACTGGGTACTACGGCTTCCTCTTGCCAGCCAGCCAGATCATCCCC
ACCGCGGAGGAGACCTGGCTAGGGCTGAAGACCATCATGGAACATGTTCGGGACCACCTCTACTAGTCAAAGAACACTTACATTTTACCTCTAAGCCACCACTTAGTTTAACATCACTTCTTCACGGA
TAGGTCGGAGCCTTCTGAGTCGGCAGAGAACTCAGCTGCCTCCTCTTCAGCATCGCTTCACAGAGATCACACCTCCTGGTAGTGAGCACGTGAGGGACACTTCTTCCGTGGAGTGGTCGGTCCCGCTG
CTCTACTGACCTTTGGTGTATATACCTCTCTATTCACGCAGCTGGTTAGGCGGGCCACAGAGGTCATGACTTCCTGGTGGCCTATGGCTACCTCACCTTTAGAACTTTGATGGTCCTCTAGTCTTTAC
CTGTAGCCTTGGGTAGGGCACCATGGGAGGTGCCAGGGGAGACAGTGCCTGTCTTCAGAACTCTGTAATTTCTCCTTCAAACATGTTCTCTCTTTTTATTTATTTATTTTTTCTTTTAGACAGGGTCT
TACTATTTTGCCCATGCTAGCCTGAAGCTCCTGGGGTCAAACTGTACCCTTCCCCGCCTCCTCCTTGCCCCATCTTCCCAGTAGTGGTATGCAGCTCAGGAACACACTTTTCTTTGAGGAAACAAATC
CTATTAGACCATCATCATTGCTCTTTCTAGCTGCGTATTCTTCCTATTCCTCCTCCTCCTCCTCCTCATCATCATCATCATGGAGACAGGATCTCTTTATGTAGCCATGACTGTCCTGGAGCTTGCTA
TATAGACCAAGCTGGCCTTGAACTTACAGAGATCTGCCTGGCTCTGCCTTCAGCATACATTAAAGATGTATTATCACCATACCTGGCTCATCTTAATTCTTTTCTGTTGGCTCGAGCACACAGTCAAG
CTCTTGTCCATTACAAGGCTCAGTGTTCAGGTGATGCCCTTTGCTTTTTAAACCGTCTTTTCTTTATATGTGGTGTTACTGGGATCCTCTAAGAGGGTCAGTTAGTTATGTTGTAGGCAAGGCTCTCA
GGGGTCATGGGGAAACGGGGCTAGATTGCAGGGACAGATTAGCACCATCTGTCCTCTTGGCCTCACCACCACTCTGCCTTTTGAACTCACTTCAAAGATTTTGACCTCACCCCACAGGTCCTAAATCA
TCCCTAGAGCCTGGATAATCTCAGGGCCTCAGCACACTCCAGCTCCGGCTCTGGTGTGCCCTGCGTTTCAGGCTCCTGGTTTCTGTCCTCCTGTGTTTAATGTTACTTTCTATTTTGCATCCTGAACC
CTGAGTACCTACCTGAAACAAGACTTCGTCAACAGCTAGACACTTCCTGTTCTCTCCTTAGCACATACTGTCTGCCCTGTTTGTGTTGTGGTTTTTGTGTTTTTGTTTTCTTGTGGGTATTTTTTTTT
TTCTTTTTCTGTTTTCAATCATGTCTATAAATCTTAACCTTCTGCCTAGGATTTGGGCAGCATCTGGTGTGTCCTCATAAGCCAATAAATATTCAATATGGGTCTCCTA

hide sequence


Protein RefSeqs	NP_082202	(Get FASTA)	NCBI Sequence Viewer
	XP_017177239	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH61206	(Get FASTA)	NCBI Sequence Viewer
	BAB23019	(Get FASTA)	NCBI Sequence Viewer
	BAC27090	(Get FASTA)	NCBI Sequence Viewer
	EDL13737	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000048558
	ENSMUSP00000048558.6
GenBank Protein	Q6P8K8	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_082202 ⟸ NM_027926
- Peptide Label:	preproprotein
- UniProtKB:	Q8BMK6 (UniProtKB/Swiss-Prot), Q9CTE6 (UniProtKB/Swiss-Prot), Q6P8K8 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MKWLLFFGALIGAGICGRDKFFGDQVFRINVRNGDEIRKLTELVNSDHLKLSVWKSPSTFDRPVDILVPSVSLLPVKSFLKSQGLDYSVTIEDLQALLDNEDEEMQHNEGIERSGDFNYGAYHPLEAI YHEMDSIATDFPELVSRVKIGETFEKRPMYVLKFSTGGGKKRPAIWLNAGIHAREWISQATAIWTARKIVTDYKKDPAITSILKKVDIFLLPVANPDGYVYTQSQNRLWRKTRSRNPGSRCVGADPNR NWNASFAGEGTSDNPCSEVYHGSHPNSEVEVKSVVDFIQKHGNFKCFIDLHSYSQLLMYPYGYTVKKAPDAEELDDVARNAAQALASLSGTKYRVGPTCTTVYPASGSSVDWAYDNGIKYAFTFELRD TGYYGFLLPASQIIPTAEETWLGLKTIMEHVRDHLY hide sequence

RefSeq Acc Id:

XP_017177239 ⟸ XM_017321750

- Peptide Label:

isoform X1

- Sequence:

show sequence

MKWLLFFGALIGAGICGRDKFFGSFSPHPSPAAPPTRPFPLILSSSVWDGGFGGLLASRKLTII
FFSLPFSRDQVFRINVRNGDEIRKLTELVNSDHLKLSVWKSPSTFDRPVDILVPSVSLLPVKSFLKSQGLDYSVTIEDLQALLDNEDEEMQHNEGIERSGDFNYGAYHPLEAIYHEMDSIATDFPELV
SRVKIGETFEKRPMYVLKFSTGGGKKRPAIWLNAGIHAREWISQATAIWTARKIVTDYKKDPAITSILKKVDIFLLPVANPDGYVYTQSQNRLWRKTRSRNPGSRCVGADPNRNWNASFAGEGTSDNP
CSEVYHGSHPNSEVEVKSVVDFIQKHGNFKCFIDLHSYSQLLMYPYGYTVKKAPDAEELDDVARNAAQALASLSGTKYRVGPTCTTVYPASGSSVDWAYDNGIKYAFTFELRDTGYYGFLLPASQIIP
TAEETWLGLKTIMEHVRDHLY

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Ensembl Acc Id:

ENSMUSP00000048558 ⟸ ENSMUST00000049251

Protein Domains

Peptidase M14

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6P8K8-F1-model_v2	AlphaFold	Q6P8K8	1-420	view protein structure

RGD ID:

6889236

Promoter ID:

EPDNEW_M8069

Type:

single initiation site

Name:

Cpa4_1

Description:

Mus musculus carboxypeptidase A4 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	6	30,568,376 - 30,568,436	EPDNEW

Database	Acc Id	Source(s)
Ensembl Genes	ENSMUSG00000039070	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000049251	ENTREZGENE
	ENSMUST00000049251.6	UniProtKB/Swiss-Prot
Gene3D-CATH	3.30.70.340	UniProtKB/Swiss-Prot
	Zn peptidases	UniProtKB/Swiss-Prot
InterPro	CPA_M14_CPD	UniProtKB/Swiss-Prot
	M14A-like_propep	UniProtKB/Swiss-Prot
	M14A_act_pep	UniProtKB/Swiss-Prot
	Peptidase_M14	UniProtKB/Swiss-Prot
KEGG Report	mmu:71791	UniProtKB/Swiss-Prot
MGD	MGI:1919041	ENTREZGENE
NCBI Gene	71791	ENTREZGENE
PANTHER	CARBOXYPEPTIDASE A4	UniProtKB/Swiss-Prot
	PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B	UniProtKB/Swiss-Prot
Pfam	Peptidase_M14	UniProtKB/Swiss-Prot
	Propep_M14	UniProtKB/Swiss-Prot
PhenoGen	Cpa4	PhenoGen
PRINTS	CRBOXYPTASEA	UniProtKB/Swiss-Prot
PROSITE	CARBOXYPEPT_ZN_1	UniProtKB/Swiss-Prot
	CARBOXYPEPT_ZN_2	UniProtKB/Swiss-Prot
	PEPTIDASE_M14	UniProtKB/Swiss-Prot
SMART	Zn_pept	UniProtKB/Swiss-Prot
Superfamily-SCOP	Protease propeptides/inhibitors	UniProtKB/Swiss-Prot
	Zn-dependent exopeptidases	UniProtKB/Swiss-Prot
UniProt	CBPA4_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
	Q8BMK6	ENTREZGENE
	Q9CTE6	ENTREZGENE
UniProt Secondary	Q8BMK6	UniProtKB/Swiss-Prot
	Q9CTE6	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - ClinVar