CPA4 (carboxypeptidase A4) - Rat Genome Database

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Gene: CPA4 (carboxypeptidase A4) Sus scrofa
Analyze
Symbol: CPA4
Name: carboxypeptidase A4
RGD ID: 14220030
Description: ENCODES a protein that exhibits carboxypeptidase activity (inferred); metal ion binding (inferred); metallocarboxypeptidase activity (inferred); INVOLVED IN hormone catabolic process (inferred); peptide catabolic process (inferred); proteolysis (inferred); ASSOCIATED WITH pleomorphic xanthoastrocytoma (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1818,530,867 - 18,553,634 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11818,528,998 - 18,553,944 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21819,395,015 - 19,408,487 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CPA4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1818,530,867 - 18,553,634 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11818,528,998 - 18,553,944 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21819,395,015 - 19,408,487 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CPA4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387130,293,161 - 130,324,180 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7130,293,134 - 130,324,180 (+)EnsemblGRCh38hg38GRCh38
GRCh377129,933,001 - 129,964,020 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367129,720,230 - 129,751,250 (+)NCBINCBI36Build 36hg18NCBI36
Build 347129,526,964 - 129,557,968NCBI
Celera7124,728,740 - 124,759,787 (+)NCBICelera
Cytogenetic Map7q32.2NCBI
HuRef7124,295,376 - 124,326,433 (+)NCBIHuRef
CHM1_17129,866,434 - 129,897,482 (+)NCBICHM1_1
T2T-CHM13v2.07131,606,545 - 131,637,922 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27129,318,357 - 129,349,405 (+)NCBI
Cpa4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39630,568,368 - 30,592,417 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl630,568,368 - 30,592,417 (+)EnsemblGRCm39 Ensembl
GRCm38630,568,369 - 30,592,418 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl630,568,369 - 30,592,418 (+)EnsemblGRCm38mm10GRCm38
MGSCv37630,518,376 - 30,541,747 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36630,518,386 - 30,541,757 (+)NCBIMGSCv36mm8
Celera630,578,234 - 30,601,732 (+)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map612.52NCBI
Cpa4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8460,155,675 - 60,179,644 (+)NCBIGRCr8
mRatBN7.2459,188,284 - 59,212,255 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl459,188,284 - 59,212,255 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx464,166,435 - 64,190,319 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0460,082,621 - 60,106,503 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0458,484,547 - 58,508,431 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0457,883,849 - 57,907,826 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl457,883,849 - 57,907,826 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0457,644,770 - 57,668,743 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4457,479,967 - 57,503,748 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera454,286,758 - 54,310,882 (+)NCBICelera
Cytogenetic Map4q22NCBI
Cpa4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547910,940,215 - 10,966,081 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547910,940,269 - 10,963,629 (+)NCBIChiLan1.0ChiLan1.0
CPA4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26167,114,272 - 167,146,577 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1719,124,536 - 19,155,770 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07122,266,946 - 122,289,742 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17134,776,768 - 134,807,678 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7134,776,768 - 134,807,678 (+)Ensemblpanpan1.1panPan2
CPA4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1146,613,878 - 6,642,833 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl146,621,039 - 6,642,793 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha146,301,778 - 6,328,836 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0146,376,095 - 6,403,156 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl146,381,873 - 6,403,090 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1146,581,072 - 6,608,656 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0146,326,280 - 6,353,327 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0146,469,905 - 6,496,964 (-)NCBIUU_Cfam_GSD_1.0
Cpa4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511824,818,561 - 24,840,243 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365794,952,365 - 4,972,837 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365794,952,235 - 4,972,842 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CPA4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12198,924,054 - 98,979,674 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2198,924,100 - 98,955,260 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660424,448,540 - 4,479,752 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cpa4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247835,976,691 - 5,999,815 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247835,976,784 - 5,999,366 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CPA4
369 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 2 22 3 2 5 10 10 22 2 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000018025   ⟹   ENSSSCP00000017540
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1818,530,867 - 18,553,634 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000029585   ⟹   ENSSSCP00000019158
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1818,530,867 - 18,553,634 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000066492   ⟹   ENSSSCP00000067207
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1818,530,759 - 18,581,003 (-)Ensembl
RefSeq Acc Id: XM_021078825   ⟹   XP_020934484
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11818,528,998 - 18,553,944 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020934484   ⟸   XM_021078825
- UniProtKB: A0A4X1VT50 (UniProtKB/TrEMBL),   I3L559 (UniProtKB/TrEMBL),   A0A8D0ISW3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000019158   ⟸   ENSSSCT00000029585
Ensembl Acc Id: ENSSSCP00000067207   ⟸   ENSSSCT00000066492
Ensembl Acc Id: ENSSSCP00000017540   ⟸   ENSSSCT00000018025

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000016555 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025004411 UniProtKB/TrEMBL
  ENSSSCG00030072688 UniProtKB/TrEMBL
  ENSSSCG00035071223 UniProtKB/TrEMBL
  ENSSSCG00040065872 UniProtKB/TrEMBL
  ENSSSCG00045013380 UniProtKB/TrEMBL
  ENSSSCG00050030654 UniProtKB/TrEMBL
  ENSSSCG00055025315 UniProtKB/TrEMBL
  ENSSSCG00060054191 UniProtKB/TrEMBL
  ENSSSCG00065048392 UniProtKB/TrEMBL
  ENSSSCG00070027518 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000018025.5 UniProtKB/TrEMBL
  ENSSSCT00000029585 ENTREZGENE
  ENSSSCT00000029585.4 UniProtKB/TrEMBL
  ENSSSCT00025005933.1 UniProtKB/TrEMBL
  ENSSSCT00025005940.1 UniProtKB/TrEMBL
  ENSSSCT00030101820.1 UniProtKB/TrEMBL
  ENSSSCT00035096255.1 UniProtKB/TrEMBL
  ENSSSCT00035096259.1 UniProtKB/TrEMBL
  ENSSSCT00040090163.1 UniProtKB/TrEMBL
  ENSSSCT00045022881.1 UniProtKB/TrEMBL
  ENSSSCT00045022890.1 UniProtKB/TrEMBL
  ENSSSCT00050041213.1 UniProtKB/TrEMBL
  ENSSSCT00055050159.1 UniProtKB/TrEMBL
  ENSSSCT00055050232.1 UniProtKB/TrEMBL
  ENSSSCT00060073766.1 UniProtKB/TrEMBL
  ENSSSCT00065066186.1 UniProtKB/TrEMBL
  ENSSSCT00065066192.1 UniProtKB/TrEMBL
  ENSSSCT00070055189.1 UniProtKB/TrEMBL
  ENSSSCT00070055195.1 UniProtKB/TrEMBL
  ENSSSCT00070055197.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.340 UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro CPA_M14_CPD UniProtKB/TrEMBL
  M14A-like_propep UniProtKB/TrEMBL
  M14A_act_pep UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
NCBI Gene CPA4 ENTREZGENE
PANTHER CARBOXYPEPTIDASE A4 UniProtKB/TrEMBL
  PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B UniProtKB/TrEMBL
Pfam Peptidase_M14 UniProtKB/TrEMBL
  Propep_M14 UniProtKB/TrEMBL
PRINTS CRBOXYPTASEA UniProtKB/TrEMBL
PROSITE CARBOXYPEPT_ZN_1 UniProtKB/TrEMBL
  CARBOXYPEPT_ZN_2 UniProtKB/TrEMBL
SMART Zn_pept UniProtKB/TrEMBL
Superfamily-SCOP Protease propeptides/inhibitors UniProtKB/TrEMBL
  Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt A0A4X1VT46_PIG UniProtKB/TrEMBL
  A0A4X1VT50 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1VY72_PIG UniProtKB/TrEMBL
  A0A8D0ISW3 ENTREZGENE, UniProtKB/TrEMBL
  F1SNE0_PIG UniProtKB/TrEMBL
  I3L559 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:103931 ENTREZGENE