Cfap157 (cilia and flagella associated protein 157) - Rat Genome Database

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Gene: Cfap157 (cilia and flagella associated protein 157) Mus musculus
Analyze
Symbol: Cfap157
Name: cilia and flagella associated protein 157
RGD ID: 1622083
MGI Page MGI
Description: Enables microtubule binding activity. Involved in sperm axoneme assembly. Located in ciliary basal body. Is expressed in several structures, including genitourinary system; nasal epithelium; node; respiratory system; and snout. Orthologous to human CFAP157 (cilia and flagella associated protein 157).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 1700019L03Rik; cilia- and flagella-associated protein 157; hypothetical protein LOC227736; uncharacterized protein C9orf117 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39232,667,425 - 32,674,417 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl232,667,393 - 32,674,440 (-)EnsemblGRCm39 Ensembl
GRCm38232,777,413 - 32,784,405 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl232,777,381 - 32,784,428 (-)EnsemblGRCm38mm10GRCm38
MGSCv37232,632,933 - 32,639,925 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36232,599,382 - 32,606,437 (-)NCBIMGSCv36mm8
Celera232,484,270 - 32,491,262 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11125038   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:17971504   PMID:21873635  
PMID:27153500   PMID:27965440  


Genomics

Comparative Map Data
Cfap157
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39232,667,425 - 32,674,417 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl232,667,393 - 32,674,440 (-)EnsemblGRCm39 Ensembl
GRCm38232,777,413 - 32,784,405 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl232,777,381 - 32,784,428 (-)EnsemblGRCm38mm10GRCm38
MGSCv37232,632,933 - 32,639,925 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36232,599,382 - 32,606,437 (-)NCBIMGSCv36mm8
Celera232,484,270 - 32,491,262 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
CFAP157
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389127,706,988 - 127,716,002 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9127,706,988 - 127,716,002 (+)EnsemblGRCh38hg38GRCh38
GRCh379130,469,267 - 130,478,281 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369129,509,092 - 129,516,124 (+)NCBINCBI36Build 36hg18NCBI36
Build 349127,548,821 - 127,555,854NCBI
Celera9101,120,163 - 101,127,195 (+)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9100,085,386 - 100,092,416 (+)NCBIHuRef
CHM1_19130,620,463 - 130,627,484 (+)NCBICHM1_1
T2T-CHM13v2.09139,913,943 - 139,922,957 (+)NCBIT2T-CHM13v2.0
Cfap157
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8336,464,219 - 36,471,193 (-)NCBIGRCr8
mRatBN7.2316,066,521 - 16,073,504 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl316,066,521 - 16,073,495 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx319,134,753 - 19,141,739 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0327,719,760 - 27,726,746 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0325,971,571 - 25,978,555 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0311,813,575 - 11,820,549 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl311,813,575 - 11,820,549 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0317,150,545 - 17,157,519 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4311,751,896 - 11,759,224 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera310,806,227 - 10,813,132 (-)NCBICelera
Cytogenetic Map3p11NCBI
Cfap157
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955419942,270 - 950,922 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955419942,147 - 950,968 (-)NCBIChiLan1.0ChiLan1.0
CFAP157
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21111,639,780 - 11,648,838 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1911,642,127 - 11,651,185 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0998,825,719 - 98,834,780 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19127,497,791 - 127,504,819 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9127,497,791 - 127,506,177 (+)Ensemblpanpan1.1panPan2
CFAP157
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1955,678,266 - 55,684,757 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl955,678,264 - 55,727,680 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha954,871,482 - 54,877,371 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0956,599,727 - 56,605,609 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl956,599,725 - 56,605,551 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1955,359,965 - 55,366,082 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0955,674,680 - 55,680,562 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0955,765,924 - 55,771,807 (-)NCBIUU_Cfam_GSD_1.0
Cfap157
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947195,614,857 - 195,621,306 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648715,383,429 - 15,392,967 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648715,383,428 - 15,389,831 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CFAP157
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1268,209,187 - 268,215,859 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11268,209,190 - 268,213,909 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21302,100,692 - 302,105,712 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CFAP157
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11210,418,854 - 10,426,739 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1210,416,855 - 10,426,124 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660795,795,159 - 5,804,205 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cfap157
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247607,821,616 - 7,829,425 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247607,821,511 - 7,829,481 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cfap157
401 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:387
Count of miRNA genes:313
Interacting mature miRNAs:348
Transcripts:ENSMUST00000102813, ENSMUST00000150918
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552706Cia24_mcollagen induced arthritis QTL 24 (mouse)Not determined22467911533523172Mouse
8552707Cia23_mcollagen induced arthritis QTL 23 (mouse)Not determined21212953766556453Mouse
12904005Cfq2_mconditioned fear QTL 2 (mouse)22702264256396228Mouse
14746979Manh51_mmandible shape 51 (mouse)22896112962961129Mouse
1300624Insq7_minsulin QTL 7 (mouse)Not determined2938444643384575Mouse
8552705Cia25_mcollagen induced arthritis 25 (mouse)Not determined22467911533523172Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
26884438Sklq12_mskull length QTL 12, 16 week (mouse)22459001254890012Mouse
12904008Cfq6_mconditioned fear QTL 6 (mouse)23120303544508204Mouse
1301790Pcfm1_mperiosteal circumference and femur length 1 (mouse)Not determined2823629642236396Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
4142130Pgis2_mproteoglycan induced spondylitis 2 (mouse)Not determined22530805156971811Mouse
1301980Fcsa5_mfemoral cross-sectional area 5 (mouse)Not determined2767911541679261Mouse
1301376Etohc1_methanol consumption 1 (mouse)Not determined22112972555129871Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
14746997Mancz2_mmandible centroid size 2 (mouse)22896112962961129Mouse
12792980Fbmd1_mfemoral bone mineral density 1, females only (mouse)22503449245034492Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1301641Sbmd2_mspinal bone mineral density 2 (mouse)Not determined21421456748214713Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
10755513Amzn4_manatomical modifier of Zfp423 4 (mouse)2938444643384575Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
13463470Tubisq1_mtubulointerstitial injury severity, QTL 1 (mouse)22368914557689269Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
1300577Capsq1_mcapsaicin sensitivity related QTL 1 (mouse)Not determined22760206084013384Mouse
4141708Pbwg1.2_mpostnatal body weight growth 1.2 (mouse)Not determined2112972555129871Mouse
10043876Adip22_madiposity 22 (mouse)Not determined2830805142308240Mouse

Markers in Region
AW046744  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38232,777,422 - 32,777,519UniSTSGRCm38
MGSCv37232,632,942 - 32,633,039UniSTSGRCm37
Celera232,484,279 - 32,484,376UniSTS
Cytogenetic Map2BUniSTS
Whitehead/MRC_RH2541.87UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000102813   ⟹   ENSMUSP00000099877
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl232,667,393 - 32,674,440 (-)Ensembl
GRCm38.p6 Ensembl232,777,381 - 32,784,428 (-)Ensembl
Ensembl Acc Id: ENSMUST00000150918
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl232,668,227 - 32,669,158 (-)Ensembl
GRCm38.p6 Ensembl232,778,215 - 32,779,146 (-)Ensembl
RefSeq Acc Id: NM_025619   ⟹   NP_079895
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39232,667,425 - 32,674,417 (-)NCBI
GRCm38232,777,413 - 32,784,405 (-)ENTREZGENE
MGSCv37232,632,933 - 32,639,925 (-)RGD
Celera232,484,270 - 32,491,262 (-)RGD
cM Map2 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_079895 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI18618 (Get FASTA)   NCBI Sequence Viewer  
  AAI21826 (Get FASTA)   NCBI Sequence Viewer  
  BAB24421 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000099877
  ENSMUSP00000099877.2
GenBank Protein Q0VFX2 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_079895   ⟸   NM_025619
- UniProtKB: Q9DA63 (UniProtKB/Swiss-Prot),   Q0VFX2 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000099877   ⟸   ENSMUST00000102813

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q0VFX2-F1-model_v2 AlphaFold Q0VFX2 1-523 view protein structure

Promoters
RGD ID:6830545
Promoter ID:MM_KWN:28760
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   MEF_B6
Transcripts:ENSMUST00000102813
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36232,639,711 - 32,640,792 (-)MPROMDB
RGD ID:6877048
Promoter ID:EPDNEW_M1975
Type:multiple initiation site
Name:Cfap157_1
Description:Mus musculus cilia and flagella associated protein 157 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38232,784,430 - 32,784,490EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2447809 AgrOrtholog
Ensembl Genes ENSMUSG00000038987 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000102813 ENTREZGENE
  ENSMUST00000102813.2 UniProtKB/Swiss-Prot
InterPro CFAP157 UniProtKB/Swiss-Prot
KEGG Report mmu:227736 UniProtKB/Swiss-Prot
MGD MGI:2447809 ENTREZGENE
NCBI Gene 227736 ENTREZGENE
PANTHER CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157 UniProtKB/Swiss-Prot
  PTHR31954 UniProtKB/Swiss-Prot
PhenoGen Cfap157 PhenoGen
UniProt CF157_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q9DA63 ENTREZGENE
UniProt Secondary Q9DA63 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-17 Cfap157  cilia and flagella associated protein 157  1700019L03Rik  RIKEN cDNA 1700019L03 gene  Symbol and/or name change 5135510 APPROVED