Ssh1 (slingshot protein phosphatase 1) - Rat Genome Database

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Gene: Ssh1 (slingshot protein phosphatase 1) Mus musculus
Analyze
Symbol: Ssh1
Name: slingshot protein phosphatase 1
RGD ID: 1622076
MGI Page MGI
Description: Predicted to enable actin binding activity and phosphoprotein phosphatase activity. Predicted to be involved in several processes, including excitatory chemical synaptic transmission; modulation of chemical synaptic transmission; and positive regulation of AMPA glutamate receptor clustering. Predicted to act upstream of or within cellular response to ATP and regulation of protein metabolic process. Predicted to be located in cell leading edge; growth cone; and plasma membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; eye epithelium; genitourinary system; and hemolymphoid system gland. Orthologous to human SSH1 (slingshot protein phosphatase 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AW551225; Gm1394; Gm1395; mSSH; mSSH-1L; protein phosphatase Slingshot homolog 1; slingshot 1L; slingshot homolog 1; slingshot homolog 1 (Drosophila); slingshot-like 1; SSH-1; SSH-1L; SSH-like protein 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395114,075,155 - 114,131,864 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5114,075,155 - 114,131,955 (-)EnsemblGRCm39 Ensembl
GRCm385113,937,094 - 113,993,803 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5113,937,094 - 113,993,894 (-)EnsemblGRCm38mm10GRCm38
MGSCv375114,392,228 - 114,443,766 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365114,203,218 - 114,254,755 (-)NCBIMGSCv36mm8
Celera5111,045,062 - 111,096,571 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map555.82NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell leading edge  (IEA,ISO)
cell projection  (ISO)
cleavage furrow  (IEA)
cytoplasm  (IBA,IEA,ISO)
cytoskeleton  (IEA)
growth cone  (IEA,ISO)
midbody  (IEA)
plasma membrane  (ISO)
synapse  (IEA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Arp2/3- and cofilin-coordinated actin dynamics is required for insulin-mediated GLUT4 translocation to the surface of muscle cells. Chiu TT, etal., Mol Biol Cell. 2010 Oct 15;21(20):3529-39. doi: 10.1091/mbc.E10-04-0316. Epub 2010 Aug 25.
2. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Slingshot isoform-specific regulation of cofilin-mediated vascular smooth muscle cell migration and neointima formation. Torres RA, etal., Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2424-31. doi: 10.1161/ATVBAHA.111.232769.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12520002   PMID:14531860   PMID:14610273   PMID:15368895  
PMID:15489334   PMID:15660133   PMID:15782199   PMID:16141072   PMID:16141073   PMID:17535256   PMID:18799693   PMID:19000834   PMID:21267068   PMID:21677750   PMID:21857021   PMID:21873635  
PMID:22282498   PMID:24345679   PMID:26273529   PMID:26686473   PMID:27588418   PMID:28378742   PMID:28671696   PMID:30228103   PMID:30291325   PMID:32325033   PMID:33044112   PMID:36092812  
PMID:37463212   PMID:37837551   PMID:38355793  


Genomics

Comparative Map Data
Ssh1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395114,075,155 - 114,131,864 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5114,075,155 - 114,131,955 (-)EnsemblGRCm39 Ensembl
GRCm385113,937,094 - 113,993,803 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5113,937,094 - 113,993,894 (-)EnsemblGRCm38mm10GRCm38
MGSCv375114,392,228 - 114,443,766 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365114,203,218 - 114,254,755 (-)NCBIMGSCv36mm8
Celera5111,045,062 - 111,096,571 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map555.82NCBI
SSH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812108,778,191 - 108,857,583 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12108,778,191 - 108,857,590 (-)EnsemblGRCh38hg38GRCh38
GRCh3712109,171,967 - 109,251,359 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612107,705,099 - 107,775,480 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412107,683,435 - 107,753,817NCBI
Celera12108,845,298 - 108,920,242 (-)NCBICelera
Cytogenetic Map12q24.11NCBI
HuRef12106,241,529 - 106,316,009 (-)NCBIHuRef
CHM1_112109,144,150 - 109,219,118 (-)NCBICHM1_1
T2T-CHM13v2.012108,752,810 - 108,832,275 (-)NCBIT2T-CHM13v2.0
Ssh1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81248,281,756 - 48,343,812 (+)NCBIGRCr8
mRatBN7.21242,621,127 - 42,683,262 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1242,621,135 - 42,683,274 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01248,403,184 - 48,447,964 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1248,403,797 - 48,446,977 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01250,186,534 - 50,230,469 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,660,409 - 43,714,743 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11243,510,743 - 43,575,432 (+)NCBI
Celera1244,244,046 - 44,282,157 (+)NCBICelera
Cytogenetic Map12q16NCBI
Ssh1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545510,020,465 - 10,053,476 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545510,019,992 - 10,077,485 (-)NCBIChiLan1.0ChiLan1.0
SSH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210116,846,321 - 116,921,476 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112116,842,719 - 116,917,868 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012106,357,147 - 106,432,295 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112109,753,103 - 109,823,442 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12109,758,399 - 109,823,444 (-)Ensemblpanpan1.1panPan2
SSH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12618,074,229 - 18,136,001 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2618,074,075 - 18,131,185 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2617,665,996 - 17,727,738 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02618,418,071 - 18,479,821 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2618,417,662 - 18,479,652 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12617,875,377 - 17,937,286 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02618,408,967 - 18,470,721 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02618,427,702 - 18,489,499 (+)NCBIUU_Cfam_GSD_1.0
Ssh1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118144,755,039 - 144,815,370 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936769669,793 - 697,893 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936769665,146 - 721,131 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SSH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1441,968,466 - 42,025,726 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11441,963,946 - 42,030,842 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21444,506,881 - 44,573,822 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SSH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111103,982,889 - 104,059,673 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037141,038,724 - 141,114,755 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ssh1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474712,019,702 - 12,081,354 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474712,017,371 - 12,081,452 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3260
Count of miRNA genes:884
Interacting mature miRNAs:1194
Transcripts:ENSMUST00000077689, ENSMUST00000112298, ENSMUST00000159510, ENSMUST00000159592, ENSMUST00000162322, ENSMUST00000162396
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587386871121387065Mouse
25314310Syncl4_msynaptonemal complex length 4 (mouse)5103047866115538059Mouse
1357725Eae39_mexperimental allergic encephalomyelitis 39 (mouse)Not determined589418876118864028Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574460661132528839Mouse
14746986Manh58_mmandible shape 58 (mouse)5102446283136446283Mouse
25314317Sccor3_msynaptonemal complex length to mean MLH1 count ratio 3 (mouse)5104347866114738061Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590561006124561151Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587386871121387065Mouse
1300659Pcd8ts1_mp-glycoprotein positive CD8 T cell subset 1 (mouse)Not determined597021753131021986Mouse
1301042Elmaz1_melevated maze behavior 1 (mouse)Not determined598019649116876624Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109439348143439459Mouse
10402486Dipa1_mdrug induced psychomotor activation 1 (mouse)Not determined595465549129465722Mouse
1357886Diht_mdopamine-induced hypothermia (mouse)Not determined5104498738115101540Mouse
10043958Chldq12_mcholesterol and HDL QTL 12 (mouse)Not determined587386871121387065Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)570057343132528839Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109238624139118905Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104583688138555455Mouse
12904945Tammq2_mtibialis anterior muscle mass QTL 2 (mouse)5100665965134665965Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107906299141906412Mouse
1301419Cypr3_mcytokine production 3 (mouse)Not determined581019649115019803Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109167240143167381Mouse
12904959Smmq1_msoleus muscle mass QTL 1 (mouse)5100665965134665965Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574460661132528839Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
1301457Cfsw2_mcystic fibrosis survival to weaning 2 (mouse)Not determined590561006124561151Mouse
10401245Bglu18_mblood glucose level 18 (mouse)Not determined582838468116838597Mouse
1301974Chab7_mcholesterol absorption 7 (mouse)Not determined595233214129233330Mouse
11528550Sluc33_msusceptibility to lung cancer 33 (mouse)5104386871120711986Mouse
1357662Lprq4_mlipoprotein QTL 4 (mouse)Not determined5114021753129632606Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554500177127001072Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104705939138705939Mouse
1300801Drb2_mdopamine receptor binding 2 (mouse)Not determined587386871121387065Mouse
9587780Afw16_mabdominal fat weight QTL 16 (mouse)Not determined592830166126830285Mouse
1357644Egrd1_mearly growth rate, direct effect 1 (mouse)Not determined595434580129434786Mouse
12859290Criq2_mCitrobacter rodentium infection QTL 2 (mouse)5101332579135332579Mouse
1300940Actd3_mactivity-distance traveled 3 (mouse)Not determined596320385130320533Mouse
10755524Mono1_mmonocyte differential 1 (mouse)580849259114849259Mouse
1558774Lith17_mlithogenic gene 17 (mouse)Not determined595465549129465722Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575315348120018629Mouse
1301624Aevm2_mautoimmune extremity vasculitis in MRL mice 2 (mouse)Not determined5101863832135864028Mouse
4141652Mrdq2_mmodifier of retinal degeneration QTL 2 (mouse)Not determined110253106118093673Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107906299141906412Mouse
4141139Hmtb4_mhemostasis and thrombosis rebleeding time 4 (mouse)Not determined108762509126882944Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102945037136945196Mouse
4141519Hmtb5_mhemostasis and thrombosis bleeding time 5 (mouse)Not determined99949422126882944Mouse
1301858Smdq1_msegregation of mitochondrial DNA QTL 1 (mouse)Not determined597021753131021986Mouse
11049562Lmr24f_mleishmaniasis resistance 24f (mouse)590320962124321041Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109167240143167381Mouse
13464244Ahl19_mage related hearing loss, early onset 19 (mouse)595465549129465722Mouse
1300968Skts4_mskin tumor susceptibility 4 (mouse)Not determined589418876124238239Mouse
13464241Ahl18_mage related hearing loss, early onset 18 (mouse)587386871121387065Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113320385138555455Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107906299141906412Mouse
13464242Ahl17_mage related hearing loss, early onset 17 (mouse)582838468116838597Mouse

Markers in Region
AW551225  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385113,937,434 - 113,937,523UniSTSGRCm38
MGSCv375114,387,443 - 114,387,532UniSTSGRCm37
Celera5111,040,278 - 111,040,367UniSTS
Cytogenetic Map5FUniSTS
Whitehead/MRC_RH51363.56UniSTS
UniSTS:235266  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385113,940,568 - 113,940,910UniSTSGRCm38
MGSCv375114,390,577 - 114,390,919UniSTSGRCm37
Celera5111,043,411 - 111,043,753UniSTS
Cytogenetic Map5FUniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001363469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_198109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006530288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011248193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB099287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC145559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK173144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB078364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC046529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY282063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000077689   ⟹   ENSMUSP00000076873
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5114,080,253 - 114,127,804 (-)Ensembl
GRCm38.p6 Ensembl5113,942,192 - 113,989,743 (-)Ensembl
Ensembl Acc Id: ENSMUST00000112298   ⟹   ENSMUSP00000107917
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5114,077,826 - 114,131,840 (-)Ensembl
GRCm38.p6 Ensembl5113,939,765 - 113,993,779 (-)Ensembl
Ensembl Acc Id: ENSMUST00000159510   ⟹   ENSMUSP00000125025
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5114,099,454 - 114,131,888 (-)Ensembl
GRCm38.p6 Ensembl5113,961,393 - 113,993,827 (-)Ensembl
Ensembl Acc Id: ENSMUST00000159592   ⟹   ENSMUSP00000124312
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5114,075,155 - 114,131,955 (-)Ensembl
GRCm38.p6 Ensembl5113,937,094 - 113,993,894 (-)Ensembl
Ensembl Acc Id: ENSMUST00000162322
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5114,104,665 - 114,131,828 (-)Ensembl
GRCm38.p6 Ensembl5113,966,604 - 113,993,767 (-)Ensembl
Ensembl Acc Id: ENSMUST00000162396   ⟹   ENSMUSP00000125388
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5114,103,663 - 114,104,817 (-)Ensembl
GRCm38.p6 Ensembl5113,965,602 - 113,966,756 (-)Ensembl
RefSeq Acc Id: NM_001363469   ⟹   NP_001350398
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395114,075,155 - 114,131,851 (-)NCBI
GRCm385113,937,094 - 113,993,790 (-)NCBI
Sequence:
RefSeq Acc Id: NM_198109   ⟹   NP_932777
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395114,075,155 - 114,131,851 (-)NCBI
GRCm385113,937,094 - 113,993,790 (-)NCBI
MGSCv375114,392,228 - 114,443,766 (-)RGD
Celera5111,045,062 - 111,096,570 (-)ENTREZGENE
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006530288   ⟹   XP_006530351
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395114,075,158 - 114,111,219 (-)NCBI
GRCm385113,937,097 - 113,973,145 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011248193   ⟹   XP_011246495
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395114,075,158 - 114,117,079 (-)NCBI
GRCm385113,937,097 - 113,979,022 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030254423   ⟹   XP_030110283
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395114,075,158 - 114,131,864 (-)NCBI
GRCm385113,937,097 - 113,993,803 (-)NCBI
Sequence:
RefSeq Acc Id: NP_932777   ⟸   NM_198109
- Peptide Label: isoform 1
- UniProtKB: Q811E5 (UniProtKB/Swiss-Prot),   Q76I79 (UniProtKB/Swiss-Prot),   Q69ZM4 (UniProtKB/Swiss-Prot),   Q3TDG3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006530351   ⟸   XM_006530288
- Peptide Label: isoform X2
- UniProtKB: F8WHT2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011246495   ⟸   XM_011248193
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001350398   ⟸   NM_001363469
- Peptide Label: isoform 2
RefSeq Acc Id: XP_030110283   ⟸   XM_030254423
- Peptide Label: isoform X2
- UniProtKB: F8WHT2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000124312   ⟸   ENSMUST00000159592
Ensembl Acc Id: ENSMUSP00000125025   ⟸   ENSMUST00000159510
Ensembl Acc Id: ENSMUSP00000107917   ⟸   ENSMUST00000112298
Ensembl Acc Id: ENSMUSP00000125388   ⟸   ENSMUST00000162396
Ensembl Acc Id: ENSMUSP00000076873   ⟸   ENSMUST00000077689
Protein Domains
DEK-C   Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q76I79-F1-model_v2 AlphaFold Q76I79 1-1042 view protein structure

Promoters
RGD ID:6887652
Promoter ID:EPDNEW_M7277
Type:single initiation site
Name:Ssh1_2
Description:Mus musculus slingshot protein phosphatase 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M7278  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385113,989,743 - 113,989,803EPDNEW
RGD ID:6887654
Promoter ID:EPDNEW_M7278
Type:multiple initiation site
Name:Ssh1_1
Description:Mus musculus slingshot protein phosphatase 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M7277  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385113,993,790 - 113,993,850EPDNEW
RGD ID:6838421
Promoter ID:MM_KWN:43526
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Lung
Transcripts:OTTMUST00000063590
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365114,416,391 - 114,416,891 (-)MPROMDB
RGD ID:6849186
Promoter ID:MM_XEF:5604
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:NM_001161331
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365114,424,731 - 114,425,231 (-)MPROMDB
RGD ID:6838420
Promoter ID:MM_KWN:43528
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000063535,   OTTMUST00000063587,   OTTMUST00000063589,   OTTMUST00000063591
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365114,443,691 - 114,444,262 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2686240 AgrOrtholog
Ensembl Genes ENSMUSG00000042121 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000077689 ENTREZGENE
  ENSMUST00000077689.14 UniProtKB/TrEMBL
  ENSMUST00000112298 ENTREZGENE
  ENSMUST00000112298.10 UniProtKB/Swiss-Prot
  ENSMUST00000159510.2 UniProtKB/TrEMBL
  ENSMUST00000159592 ENTREZGENE
  ENSMUST00000159592.8 UniProtKB/Swiss-Prot
  ENSMUST00000162396.2 UniProtKB/TrEMBL
Gene3D-CATH 3.90.190.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DEK_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dual-sp_phosphatase_cat-dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phosphatase_SSH-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSH-N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSH1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:231637 UniProtKB/Swiss-Prot
MGD MGI:2686240 ENTREZGENE
NCBI Gene Ssh1 ENTREZGENE
PANTHER PTHR45864 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45864:SF5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DEK_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DSPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ssh1 PhenoGen
PROSITE DEK_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DSPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP DEK C-terminal domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52799 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt E0CXT3_MOUSE UniProtKB/TrEMBL
  F7CBJ9_MOUSE UniProtKB/TrEMBL
  F8WHT2 ENTREZGENE, UniProtKB/TrEMBL
  Q3TDG3 ENTREZGENE
  Q69ZM4 ENTREZGENE
  Q76I79 ENTREZGENE
  Q811E5 ENTREZGENE
  SSH1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q3TDG3 UniProtKB/Swiss-Prot
  Q69ZM4 UniProtKB/Swiss-Prot
  Q811E5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-21 Ssh1  slingshot protein phosphatase 1  Ssh1  slingshot homolog 1 (Drosophila)  Symbol and/or name change 5135510 APPROVED
2024-08-21 Ssh1  slingshot homolog 1 (Drosophila)  Ssh1  slingshot protein phosphatase 1  Symbol and/or name change 5135510 APPROVED
2017-10-24 Ssh1  slingshot protein phosphatase 1    slingshot homolog 1 (Drosophila)  Symbol and/or name change 5135510 APPROVED