Or4c116 (olfactory receptor family 4 subfamily C member 116) - Rat Genome Database

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Gene: Or4c116 (olfactory receptor family 4 subfamily C member 116) Mus musculus
Analyze
No known orthologs.
Symbol: Or4c116
Name: olfactory receptor family 4 subfamily C member 116
RGD ID: 1622018
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human OR4C15 (olfactory receptor family 4 subfamily C member 15).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GA_x6K02T2Q125-50591144-50590209; MOR233; MOR233-3; olfactory receptor 1221; olfactory receptor MOR233-3; Olfr1221
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39288,941,919 - 88,942,854 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl288,939,430 - 88,947,627 (-)EnsemblGRCm39 Ensembl
GRCm38289,111,575 - 89,112,510 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl289,109,086 - 89,117,283 (-)EnsemblGRCm38mm10GRCm38
MGSCv37288,951,732 - 88,952,667 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36288,912,414 - 88,913,349 (-)NCBIMGSCv36mm8
Celera290,694,915 - 90,695,850 (-)NCBICelera
Cytogenetic Map2E1NCBI
cM Map250.03NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or4c116Mouse1,2-dichloroethane increases expressionEXP 6480464ethylene dichloride results in increased expression of OR4C116 mRNACTDPMID:28960355
Or4c116Mousesodium fluoride decreases expressionEXP 6480464Sodium Fluoride results in decreased expression of OR4C116 mRNACTDPMID:27862939


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or4c116MouseG protein-coupled receptor signaling pathway acts_upstream_of_or_withinISAprotein_id:BAA861262290270 PMID:14611657MGIPMID:14611657
Or4c116Mousesensory perception of smell acts_upstream_of_or_withinISAprotein_id:BAA861262290270 PMID:14611657MGIPMID:14611657

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or4c116Mousemembrane located_inISAprotein_id:BAA861262290270 PMID:14611657MGIPMID:14611657
Or4c116Mouseplasma membrane is_active_inIBAPANTHER:PTN008273833 more ...2290270 GO_CentralGO_REF:0000033

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or4c116Mouseolfactory receptor activity enablesIBAPANTHER:PTN001239295 more ...2290270 GO_CentralGO_REF:0000033
Or4c116Mouseolfactory receptor activity enablesISAprotein_id:BAA861262290270 PMID:14611657MGIPMID:14611657


#
Reference Title
Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:11802173   PMID:11875048   PMID:14611657   PMID:21873635   PMID:32061665   PMID:32295537  



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Variants in Or4c116
45 total Variants

Predicted Target Of
Summary Value
Count of predictions:172
Count of miRNA genes:154
Interacting mature miRNAs:159
Transcripts:ENSMUST00000099795
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 49 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
1301405Etohr_methanol response acute (mouse)Not determined26300595497006113Mouse
1301660Iba1_minduction of brown adipocytes 1 (mouse)Not determined267647887101648142Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
11532731Sluc31a_msusceptibility to lung cancer 31a (mouse)288015003122015170Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1301897Scc2_mcolon tumor susceptibility 2 (mouse)Not determined28572426990410991Mouse

1 to 10 of 49 rows
UniSTS:485184  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38289,111,575 - 89,112,510UniSTSGRCm38
MGSCv37288,951,732 - 88,952,667UniSTSGRCm37
Celera290,694,915 - 90,695,850UniSTS
Cytogenetic Map2E1UniSTS







Ensembl Acc Id: ENSMUST00000099795   ⟹   ENSMUSP00000097383
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl288,941,919 - 88,942,854 (-)Ensembl
GRCm38.p6 Ensembl289,111,575 - 89,112,510 (-)Ensembl
Ensembl Acc Id: ENSMUST00000143255   ⟹   ENSMUSP00000150194
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl288,940,471 - 88,947,627 (-)Ensembl
GRCm38.p6 Ensembl289,110,127 - 89,117,283 (-)Ensembl
Ensembl Acc Id: ENSMUST00000213404   ⟹   ENSMUSP00000149122
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl288,940,471 - 88,947,627 (-)Ensembl
GRCm38.p6 Ensembl289,110,127 - 89,117,283 (-)Ensembl
Ensembl Acc Id: ENSMUST00000217635   ⟹   ENSMUSP00000149330
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl288,939,430 - 88,947,627 (-)Ensembl
GRCm38.p6 Ensembl289,109,086 - 89,117,283 (-)Ensembl
RefSeq Acc Id: NM_146902   ⟹   NP_667113
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39288,941,919 - 88,942,854 (-)NCBI
GRCm38289,111,575 - 89,112,510 (-)ENTREZGENE
MGSCv37288,951,732 - 88,952,667 (-)RGD
Celera290,694,915 - 90,695,850 (-)RGD
cM Map2 ENTREZGENE
Sequence:
1 to 9 of 9 rows
Protein RefSeqs NP_667113 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAL60849 (Get FASTA)   NCBI Sequence Viewer  
  AAP71621 (Get FASTA)   NCBI Sequence Viewer  
  EDL27448 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000097383
  ENSMUSP00000097383.2
  ENSMUSP00000149122.2
  ENSMUSP00000149330.2
  ENSMUSP00000150194.2
1 to 9 of 9 rows
RefSeq Acc Id: NP_667113   ⟸   NM_146902
- UniProtKB: L7MU53 (UniProtKB/TrEMBL),   Q8VGG2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000097383   ⟸   ENSMUST00000099795
Ensembl Acc Id: ENSMUSP00000149330   ⟸   ENSMUST00000217635
Ensembl Acc Id: ENSMUSP00000150194   ⟸   ENSMUST00000143255
Ensembl Acc Id: ENSMUSP00000149122   ⟸   ENSMUST00000213404
G-protein coupled receptors family 1 profile

Name Modeler Protein Id AA Range Protein Structure
AF-L7MU53-F1-model_v2 AlphaFold L7MU53 1-311 view protein structure



1 to 24 of 24 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000075102 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000099795 ENTREZGENE
  ENSMUST00000099795.2 UniProtKB/TrEMBL
  ENSMUST00000143255.3 UniProtKB/TrEMBL
  ENSMUST00000213404.2 UniProtKB/TrEMBL
  ENSMUST00000217635.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfactory_Receptors UniProtKB/TrEMBL
KEGG Report mmu:258904 UniProtKB/TrEMBL
MGD MGI:3031055 ENTREZGENE
NCBI Gene 258904 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or4c116 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt L7MU53 ENTREZGENE, UniProtKB/TrEMBL
  Q8VGG2 ENTREZGENE, UniProtKB/TrEMBL
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or4c116  olfactory receptor family 4 subfamily C member 116  Olfr1221  olfactory receptor 1221  Symbol and/or name change 5135510 APPROVED