Or4c116 (olfactory receptor family 4 subfamily C member 116) - Rat Genome Database

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Gene: Or4c116 (olfactory receptor family 4 subfamily C member 116) Mus musculus
Analyze
No known orthologs.
Symbol: Or4c116
Name: olfactory receptor family 4 subfamily C member 116
RGD ID: 1622018
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human OR4C15 (olfactory receptor family 4 subfamily C member 15).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GA_x6K02T2Q125-50591144-50590209; MOR233; MOR233-3; olfactory receptor 1221; olfactory receptor MOR233-3; Olfr1221
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39288,941,919 - 88,942,854 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl288,939,430 - 88,947,627 (-)EnsemblGRCm39 Ensembl
GRCm38289,111,575 - 89,112,510 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl289,109,086 - 89,117,283 (-)EnsemblGRCm38mm10GRCm38
MGSCv37288,951,732 - 88,952,667 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36288,912,414 - 88,913,349 (-)NCBIMGSCv36mm8
Celera290,694,915 - 90,695,850 (-)NCBICelera
Cytogenetic Map2E1NCBI
cM Map250.03NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11802173   PMID:11875048   PMID:14611657   PMID:21873635   PMID:32061665   PMID:32295537  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:172
Count of miRNA genes:154
Interacting mature miRNAs:159
Transcripts:ENSMUST00000099795
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
1301405Etohr_methanol response acute (mouse)Not determined26300595497006113Mouse
1301660Iba1_minduction of brown adipocytes 1 (mouse)Not determined267647887101648142Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
11532731Sluc31a_msusceptibility to lung cancer 31a (mouse)288015003122015170Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1301897Scc2_mcolon tumor susceptibility 2 (mouse)Not determined28572426990410991Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260520612119355518Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
1300662Etohila_methanol induced locomotor activity (mouse)Not determined26300595497006113Mouse
10053681Lith24_mlithogenic gene 24 (mouse)Not determined26300595497006113Mouse
1301048Actre2_mactivity response to ethanol 2 (mouse)Not determined26300595497006113Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
1301948Elsgp3_melevated serum gp70 3 (mouse)Not determined268724269102724407Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
15092054Egrme5_mearly growth rate, maternal effect 5 (mouse)282190187118004745Mouse
4142223Femwf4_mfemur work to failure 4 (mouse)Not determined88143423122143570Mouse
4142088Parms1_mpatched associated RMS 1 (mouse)Not determined74524117114123532Mouse
12738429Lfibq18_mliver fibrosis QTL 18 (mouse)25791999191919991Mouse
11038697Ltpr2d_mLeishmania tropica response 2d (mouse)286095716120095823Mouse
11038698Ltpr2c_mLeishmania tropica response 2c (mouse)286095716120095823Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
1301703Bomd3_mbone mineral density 3 (mouse)Not determined26300595497006113Mouse
1301834Bits1_mbitterness sensitivity 1 (mouse)Not determined287440643121440778Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
4141406Alpq2_malcohol preference QTL 2 (mouse)Not determined25752411791524288Mouse
1301873Hsl1_mhyperoxia susceptibility locus 1 (mouse)Not determined26357015497570301Mouse
1558901Skmw8_mskeletal muscle weight 8 (mouse)Not determined284008488118008593Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1301109Dntcs2_mdental caries susceptibility 2 (mouse)Not determined240885493114910165Mouse
4141657Mohg1_mmodifier of hg 1 (mouse)Not determined276678758103095823Mouse
1300852Lmr14_mleishmaniasis resistance 14 (mouse)Not determined286095716120095823Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
1301882Etohc2_methanol consumption 2 (mouse)Not determined268724269102724407Mouse
1301374Cplaq7_mcircadian period of locomotor activity 7 (mouse)Not determined276421483110421651Mouse
10043894Bw22_mbody weight QTL 22 (mouse)Not determined280895334114895334Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
11049565Lmr28g_mleishmaniasis resistance 28g (mouse)286095716120095823Mouse
13463482Mchq17_mmean corpuscular hemoglobin QTL 17 (mouse)267647887101648142Mouse
10044002Hdl7_mHDL level 7 (mouse)Not determined26300595497006113Mouse

Markers in Region
UniSTS:485184  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38289,111,575 - 89,112,510UniSTSGRCm38
MGSCv37288,951,732 - 88,952,667UniSTSGRCm37
Celera290,694,915 - 90,695,850UniSTS
Cytogenetic Map2E1UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000099795   ⟹   ENSMUSP00000097383
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl288,941,919 - 88,942,854 (-)Ensembl
GRCm38.p6 Ensembl289,111,575 - 89,112,510 (-)Ensembl
Ensembl Acc Id: ENSMUST00000143255   ⟹   ENSMUSP00000150194
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl288,940,471 - 88,947,627 (-)Ensembl
GRCm38.p6 Ensembl289,110,127 - 89,117,283 (-)Ensembl
Ensembl Acc Id: ENSMUST00000213404   ⟹   ENSMUSP00000149122
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl288,940,471 - 88,947,627 (-)Ensembl
GRCm38.p6 Ensembl289,110,127 - 89,117,283 (-)Ensembl
Ensembl Acc Id: ENSMUST00000217635   ⟹   ENSMUSP00000149330
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl288,939,430 - 88,947,627 (-)Ensembl
GRCm38.p6 Ensembl289,109,086 - 89,117,283 (-)Ensembl
RefSeq Acc Id: NM_146902   ⟹   NP_667113
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39288,941,919 - 88,942,854 (-)NCBI
GRCm38289,111,575 - 89,112,510 (-)ENTREZGENE
MGSCv37288,951,732 - 88,952,667 (-)RGD
Celera290,694,915 - 90,695,850 (-)RGD
cM Map2 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_667113 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAL60849 (Get FASTA)   NCBI Sequence Viewer  
  AAP71621 (Get FASTA)   NCBI Sequence Viewer  
  EDL27448 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000097383
  ENSMUSP00000097383.2
  ENSMUSP00000149122.2
  ENSMUSP00000149330.2
  ENSMUSP00000150194.2
RefSeq Acc Id: NP_667113   ⟸   NM_146902
- UniProtKB: L7MU53 (UniProtKB/TrEMBL),   Q8VGG2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000097383   ⟸   ENSMUST00000099795
Ensembl Acc Id: ENSMUSP00000149330   ⟸   ENSMUST00000217635
Ensembl Acc Id: ENSMUSP00000150194   ⟸   ENSMUST00000143255
Ensembl Acc Id: ENSMUSP00000149122   ⟸   ENSMUST00000213404
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-L7MU53-F1-model_v2 AlphaFold L7MU53 1-311 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3031055 AgrOrtholog
Ensembl Genes ENSMUSG00000075102 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000099795 ENTREZGENE
  ENSMUST00000099795.2 UniProtKB/TrEMBL
  ENSMUST00000143255.3 UniProtKB/TrEMBL
  ENSMUST00000213404.2 UniProtKB/TrEMBL
  ENSMUST00000217635.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfactory_Receptors UniProtKB/TrEMBL
KEGG Report mmu:258904 UniProtKB/TrEMBL
MGD MGI:3031055 ENTREZGENE
NCBI Gene 258904 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or4c116 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt L7MU53 ENTREZGENE, UniProtKB/TrEMBL
  Q8VGG2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or4c116  olfactory receptor family 4 subfamily C member 116  Olfr1221  olfactory receptor 1221  Symbol and/or name change 5135510 APPROVED