Sntn (sentan, cilia apical structure protein) - Rat Genome Database

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Gene: Sntn (sentan, cilia apical structure protein) Mus musculus
Analyze
Symbol: Sntn
Name: sentan, cilia apical structure protein
RGD ID: 1621354
MGI Page MGI
Description: Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity. Located in cilium. Is expressed in lung epithelium and nasal cavity respiratory epithelium. Orthologous to human SNTN (sentan, cilia apical structure protein).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: A430083B19Rik; protein S100-A1-like; S100 calcium-binding protein A1-like; sentan
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39148,786,615 - 8,798,887 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl148,786,615 - 8,798,887 (-)EnsemblGRCm39 Ensembl
GRCm381413,670,876 - 13,683,148 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1413,670,876 - 13,683,148 (+)EnsemblGRCm38mm10GRCm38
MGSCv371414,503,390 - 14,515,662 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361412,464,143 - 12,476,415 (+)NCBIMGSCv36mm8
Celera149,314,695 - 9,327,135 (+)NCBICelera
Cytogenetic Map14A1NCBI
cM Map146.93NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell projection  (IEA)
cilium  (IDA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:16602821   PMID:18829862   PMID:21677750   PMID:21873635  
PMID:27914912   PMID:29916806   PMID:38355793  


Genomics

Comparative Map Data
Sntn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39148,786,615 - 8,798,887 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl148,786,615 - 8,798,887 (-)EnsemblGRCm39 Ensembl
GRCm381413,670,876 - 13,683,148 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1413,670,876 - 13,683,148 (+)EnsemblGRCm38mm10GRCm38
MGSCv371414,503,390 - 14,515,662 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361412,464,143 - 12,476,415 (+)NCBIMGSCv36mm8
Celera149,314,695 - 9,327,135 (+)NCBICelera
Cytogenetic Map14A1NCBI
cM Map146.93NCBI
SNTN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38363,652,675 - 63,665,212 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl363,652,675 - 63,679,020 (+)EnsemblGRCh38hg38GRCh38
GRCh37363,638,351 - 63,650,888 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36363,613,384 - 63,625,933 (+)NCBINCBI36Build 36hg18NCBI36
Celera363,655,601 - 63,668,154 (+)NCBICelera
Cytogenetic Map3p14.2NCBI
HuRef363,735,531 - 63,748,076 (+)NCBIHuRef
CHM1_1363,589,797 - 63,602,351 (+)NCBICHM1_1
T2T-CHM13v2.0363,696,298 - 63,708,831 (+)NCBIT2T-CHM13v2.0
Sntn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81513,943,052 - 13,956,109 (-)NCBIGRCr8
mRatBN7.21511,512,563 - 11,525,608 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1511,512,563 - 11,525,603 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1513,626,907 - 13,640,013 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01514,588,819 - 14,601,924 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01512,840,191 - 12,853,297 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01514,497,770 - 14,510,828 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1514,497,770 - 14,510,828 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01518,501,194 - 18,514,256 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41513,073,259 - 13,086,693 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1511,514,566 - 11,527,178 (-)NCBICelera
Cytogenetic Map15p16NCBI
Sntn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555172,209,843 - 2,234,113 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555172,210,700 - 2,233,760 (-)NCBIChiLan1.0ChiLan1.0
SNTN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2263,578,041 - 63,590,634 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1363,582,828 - 63,595,402 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0363,560,204 - 63,572,211 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1364,941,058 - 64,952,774 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl364,941,058 - 64,964,255 (+)Ensemblpanpan1.1panPan2
SNTN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12027,532,916 - 27,548,331 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2027,533,739 - 27,547,972 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2027,457,119 - 27,472,179 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02027,769,816 - 27,784,898 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2027,769,807 - 27,784,905 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12027,266,816 - 27,281,849 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02027,616,443 - 27,631,469 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02027,719,787 - 27,734,858 (-)NCBIUU_Cfam_GSD_1.0
Sntn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118164,348,246 - 164,362,752 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366372,738,068 - 2,745,909 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366372,738,068 - 2,753,610 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNTN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1345,187,379 - 45,200,718 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11345,187,385 - 45,200,586 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21349,668,180 - 49,681,418 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SNTN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12224,697,324 - 24,709,576 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041142,113,490 - 142,125,952 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sntn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248882,278,004 - 2,289,695 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248882,277,215 - 2,290,237 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sntn
510 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:267
Count of miRNA genes:213
Interacting mature miRNAs:230
Transcripts:ENSMUST00000061045
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10412071Ssen3_msuseptibility to Sendai virus 3 (mouse)Not determined14126987934Mouse
11532711Sluc40_msusceptibility to lung cancer 40 (mouse)14127379943Mouse
13824988Phsq1_mpercent hyperactivated sperm QTL 1 (mouse)14305000119469772Mouse
1301991Wta3_mweight adult 3 (mouse)Not determined14388747337887650Mouse
4141550Dbm3_mdiabetes modifier 3 (mouse)Not determined514347339143596Mouse
4141265Appd2_mAPP associated premature death 2 (mouse)Not determined14594555230114862Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000061045   ⟹   ENSMUSP00000062092
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl148,786,615 - 8,798,887 (-)Ensembl
GRCm38.p6 Ensembl1413,670,876 - 13,683,148 (+)Ensembl
RefSeq Acc Id: NM_177624   ⟹   NP_808292
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39148,786,615 - 8,798,887 (-)NCBI
GRCm381413,670,876 - 13,683,148 (+)ENTREZGENE
MGSCv371414,503,390 - 14,515,662 (+)RGD
Celera149,314,695 - 9,327,135 (+)RGD
cM Map14 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_808292 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI26946 (Get FASTA)   NCBI Sequence Viewer  
  BAC30559 (Get FASTA)   NCBI Sequence Viewer  
  EDL20615 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000062092
  ENSMUSP00000062092.3
GenBank Protein FAA00430 (Get FASTA)   NCBI Sequence Viewer  
  Q8C9X1 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_808292   ⟸   NM_177624
- UniProtKB: B7FF66 (UniProtKB/Swiss-Prot),   Q8C9X1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000062092   ⟸   ENSMUST00000061045

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8C9X1-F1-model_v2 AlphaFold Q8C9X1 1-147 view protein structure

Promoters
RGD ID:8681524
Promoter ID:EPDNEW_M18793
Type:initiation region
Name:Sntn_1
Description:Mus musculus sentan, cilia apical structure protein , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381413,670,876 - 13,670,936EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3045373 AgrOrtholog
Ensembl Genes ENSMUSG00000044772 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000061045 ENTREZGENE
  ENSMUST00000061045.3 UniProtKB/Swiss-Prot
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot
  S-100_dom UniProtKB/Swiss-Prot
  S100_Ca-bd_sub UniProtKB/Swiss-Prot
KEGG Report mmu:218739 UniProtKB/Swiss-Prot
MGD MGI:3045373 ENTREZGENE
NCBI Gene 218739 ENTREZGENE
PANTHER PTHR11639:SF134 UniProtKB/Swiss-Prot
  S100 CALCIUM-BINDING PROTEIN UniProtKB/Swiss-Prot
Pfam S_100 UniProtKB/Swiss-Prot
PhenoGen Sntn PhenoGen
SMART S_100 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot
UniProt B7FF66 ENTREZGENE
  Q8C9X1 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B7FF66 UniProtKB/Swiss-Prot