SNTN (sentan, cilia apical structure protein) - Rat Genome Database

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Gene: SNTN (sentan, cilia apical structure protein) Canis lupus familiaris
Analyze
Symbol: SNTN
Name: sentan, cilia apical structure protein
RGD ID: 12338575
Description: ENCODES a protein that exhibits calcium ion binding (inferred); calcium-dependent protein binding (inferred); RAGE receptor binding (inferred); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (inferred); positive regulation of cell population proliferation (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cilium (inferred); extracellular space (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sentan
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12027,532,916 - 27,548,331 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2027,533,739 - 27,547,972 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2027,457,119 - 27,472,179 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02027,769,816 - 27,784,898 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2027,769,807 - 27,784,905 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12027,266,816 - 27,281,849 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02027,616,443 - 27,631,469 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02027,719,787 - 27,734,858 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
SNTN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12027,532,916 - 27,548,331 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2027,533,739 - 27,547,972 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2027,457,119 - 27,472,179 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02027,769,816 - 27,784,898 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2027,769,807 - 27,784,905 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12027,266,816 - 27,281,849 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02027,616,443 - 27,631,469 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02027,719,787 - 27,734,858 (-)NCBIUU_Cfam_GSD_1.0
SNTN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38363,652,675 - 63,665,212 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl363,652,675 - 63,679,020 (+)EnsemblGRCh38hg38GRCh38
GRCh37363,638,351 - 63,650,888 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36363,613,384 - 63,625,933 (+)NCBINCBI36Build 36hg18NCBI36
Celera363,655,601 - 63,668,154 (+)NCBICelera
Cytogenetic Map3p14.2NCBI
HuRef363,735,531 - 63,748,076 (+)NCBIHuRef
CHM1_1363,589,797 - 63,602,351 (+)NCBICHM1_1
T2T-CHM13v2.0363,696,298 - 63,708,831 (+)NCBIT2T-CHM13v2.0
Sntn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39148,786,615 - 8,798,887 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl148,786,615 - 8,798,887 (-)EnsemblGRCm39 Ensembl
GRCm381413,670,876 - 13,683,148 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1413,670,876 - 13,683,148 (+)EnsemblGRCm38mm10GRCm38
MGSCv371414,503,390 - 14,515,662 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361412,464,143 - 12,476,415 (+)NCBIMGSCv36mm8
Celera149,314,695 - 9,327,135 (+)NCBICelera
Cytogenetic Map14A1NCBI
cM Map146.93NCBI
Sntn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81513,943,052 - 13,956,109 (-)NCBIGRCr8
mRatBN7.21511,512,563 - 11,525,608 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1511,512,563 - 11,525,603 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1513,626,907 - 13,640,013 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01514,588,819 - 14,601,924 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01512,840,191 - 12,853,297 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01514,497,770 - 14,510,828 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1514,497,770 - 14,510,828 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01518,501,194 - 18,514,256 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41513,073,259 - 13,086,693 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1511,514,566 - 11,527,178 (-)NCBICelera
Cytogenetic Map15p16NCBI
Sntn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555172,209,843 - 2,234,113 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555172,210,700 - 2,233,760 (-)NCBIChiLan1.0ChiLan1.0
SNTN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2263,578,041 - 63,590,634 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1363,582,828 - 63,595,402 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0363,560,204 - 63,572,211 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1364,941,058 - 64,952,774 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl364,941,058 - 64,964,255 (+)Ensemblpanpan1.1panPan2
Sntn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118164,348,246 - 164,362,752 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366372,738,068 - 2,745,909 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366372,738,068 - 2,753,610 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNTN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1345,187,379 - 45,200,718 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11345,187,385 - 45,200,586 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21349,668,180 - 49,681,418 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SNTN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12224,697,324 - 24,709,576 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041142,113,490 - 142,125,952 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sntn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248882,278,004 - 2,289,695 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248882,277,215 - 2,290,237 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SNTN
214 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1
Low 1 4
Below cutoff 3 5 20 5 5 5 6 5 11 8 5 5

Sequence


RefSeq Acc Id: ENSCAFT00000042818   ⟹   ENSCAFP00000036397
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2027,533,739 - 27,547,972 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845024431   ⟹   ENSCAFP00845019207
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2027,769,807 - 27,784,905 (-)Ensembl
RefSeq Acc Id: XM_038427261   ⟹   XP_038283189
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02027,769,816 - 27,784,898 (-)NCBI
RefSeq Acc Id: XM_038502986   ⟹   XP_038358914
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12027,266,816 - 27,281,849 (-)NCBI
RefSeq Acc Id: XM_038565950   ⟹   XP_038421878
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02027,719,787 - 27,734,858 (-)NCBI
RefSeq Acc Id: XM_038630084   ⟹   XP_038486012
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02027,616,443 - 27,631,469 (-)NCBI
RefSeq Acc Id: XM_541819   ⟹   XP_541819
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12027,532,916 - 27,548,331 (-)NCBI
Dog10K_Boxer_Tasha2027,457,119 - 27,472,179 (-)NCBI
Sequence:
RefSeq Acc Id: XP_541819   ⟸   XM_541819
- UniProtKB: A0A8C0KA21 (UniProtKB/TrEMBL),   A0A8C0YZC9 (UniProtKB/TrEMBL),   A0A8I3NF76 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000036397   ⟸   ENSCAFT00000042818
RefSeq Acc Id: XP_038358914   ⟸   XM_038502986
RefSeq Acc Id: XP_038486012   ⟸   XM_038630084
RefSeq Acc Id: XP_038283189   ⟸   XM_038427261
- UniProtKB: A0A8C0KA21 (UniProtKB/TrEMBL),   A0A8C0YZC9 (UniProtKB/TrEMBL),   A0A8I3NF76 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038421878   ⟸   XM_038565950
- UniProtKB: A0A8C0KA21 (UniProtKB/TrEMBL),   A0A8C0YZC9 (UniProtKB/TrEMBL),   A0A8I3NF76 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845019207   ⟸   ENSCAFT00845024431
Promoters
RGD ID:13686820
Promoter ID:EPDNEW_C4888
Type:single initiation site
Name:SNTN_1
Description:sentan, cilia apical structure protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12027,547,976 - 27,548,036EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000031164 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030013963 UniProtKB/TrEMBL
  ENSCAFG00040015791 UniProtKB/TrEMBL
  ENSCAFG00845013709 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000042818.3 UniProtKB/TrEMBL
  ENSCAFT00030025852.1 UniProtKB/TrEMBL
  ENSCAFT00040029026.1 UniProtKB/TrEMBL
  ENSCAFT00845024431 ENTREZGENE
  ENSCAFT00845024431.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  S-100_dom UniProtKB/TrEMBL
  S100_Ca-bd_sub UniProtKB/TrEMBL
KEGG Report cfa:484703 UniProtKB/TrEMBL
NCBI Gene SNTN ENTREZGENE
PANTHER PTHR11639:SF134 UniProtKB/TrEMBL
  S100 CALCIUM-BINDING PROTEIN UniProtKB/TrEMBL
SMART S_100 UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A8C0KA21 ENTREZGENE
  A0A8C0YZC9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NF76 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:46617 ENTREZGENE