Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Apoo | Mouse | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of APOO mRNA | CTD | PMID:36331819 | Apoo | Mouse | 1,1-dichloroethene | decreases expression | EXP | | 6480464 | vinylidene chloride results in decreased expression of APOO mRNA | CTD | PMID:26682919 | Apoo | Mouse | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of APOO mRNA | CTD | PMID:22206623 | Apoo | Mouse | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of APOO mRNA | CTD | PMID:22206623 | Apoo | Mouse | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of APOO mRNA | CTD | PMID:19484750 | Apoo | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of APOO mRNA | CTD | PMID:24680724 | Apoo | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Apoo (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of APOO mRNA | CTD | PMID:33387578 | Apoo | Mouse | 2-methylcholine | affects expression | ISO | APOO (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of APOO mRNA | CTD | PMID:21179406 | Apoo | Mouse | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | APOO (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of APOO mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of APOO mRNA | CTD | PMID:28628672 | Apoo | Mouse | 4,4'-sulfonyldiphenol | increases methylation | ISO | APOO (Homo sapiens) | 6480464 | bisphenol S results in increased methylation of APOO gene | CTD | PMID:31601247 | Apoo | Mouse | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Apoo (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of APOO mRNA | CTD | PMID:36041667 | Apoo | Mouse | 4,4'-sulfonyldiphenol | affects expression | ISO | APOO (Homo sapiens) | 6480464 | bisphenol S affects the expression of APOO protein | CTD | PMID:31945527 | Apoo | Mouse | 6-propyl-2-thiouracil | increases expression | ISO | Apoo (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of APOO mRNA | CTD | PMID:30047161 | Apoo | Mouse | acrylamide | increases expression | ISO | APOO (Homo sapiens) | 6480464 | Acrylamide results in increased expression of APOO mRNA | CTD | PMID:32763439 | Apoo | Mouse | all-trans-retinoic acid | decreases expression | ISO | APOO (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of APOO mRNA | CTD | PMID:33167477 | Apoo | Mouse | alpha-Zearalanol | multiple interactions | ISO | Apoo (Rattus norvegicus) | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of APOO mRNA | CTD | PMID:35163327 | Apoo | Mouse | amitrole | increases expression | ISO | Apoo (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of APOO mRNA | CTD | PMID:30047161 | Apoo | Mouse | arsane | affects methylation | ISO | APOO (Homo sapiens) | 6480464 | Arsenic affects the methylation of APOO gene | CTD | PMID:25304211 | Apoo | Mouse | arsenic atom | affects methylation | ISO | APOO (Homo sapiens) | 6480464 | Arsenic affects the methylation of APOO gene | CTD | PMID:25304211 | Apoo | Mouse | atrazine | affects methylation | ISO | Apoo (Rattus norvegicus) | 6480464 | Atrazine affects the methylation of APOO gene | CTD | PMID:28931070 and PMID:35440735 | Apoo | Mouse | benzo[a]pyrene | increases expression | ISO | APOO (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of APOO mRNA | CTD | PMID:21632981 | Apoo | Mouse | benzo[a]pyrene | increases methylation | ISO | APOO (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of APOO exon | CTD | PMID:27901495 | Apoo | Mouse | benzo[e]pyrene | increases methylation | ISO | APOO (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of APOO intron | CTD | PMID:30157460 | Apoo | Mouse | bisphenol A | affects expression | ISO | Apoo (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of APOO mRNA | CTD | PMID:25181051 | Apoo | Mouse | bisphenol A | multiple interactions | ISO | Apoo (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of APOO mRNA | CTD | PMID:36041667 | Apoo | Mouse | bisphenol A | decreases methylation | ISO | APOO (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of APOO gene | CTD | PMID:31601247 | Apoo | Mouse | bisphenol A | multiple interactions | ISO | APOO (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of APOO mRNA | CTD | PMID:28628672 | Apoo | Mouse | bisphenol F | multiple interactions | ISO | APOO (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of APOO mRNA | CTD | PMID:28628672 | Apoo | Mouse | bisphenol F | multiple interactions | ISO | Apoo (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of APOO mRNA | CTD | PMID:36041667 | Apoo | Mouse | buspirone | decreases expression | ISO | Apoo (Rattus norvegicus) | 6480464 | Buspirone results in decreased expression of APOO mRNA | CTD | PMID:24136188 | Apoo | Mouse | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Apoo | Mouse | cisplatin | increases expression | ISO | APOO (Homo sapiens) | 6480464 | Cisplatin results in increased expression of APOO mRNA | CTD | PMID:27392435 | Apoo | Mouse | cisplatin | multiple interactions | ISO | APOO (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of APOO mRNA | CTD | PMID:27392435 | Apoo | Mouse | cocaine | increases expression | ISO | Apoo (Rattus norvegicus) | 6480464 | Cocaine results in increased expression of APOO protein | CTD | PMID:25100957 | Apoo | Mouse | crocidolite asbestos | decreases expression | EXP | | 6480464 | Asbestos and Crocidolite results in decreased expression of APOO mRNA | CTD | PMID:29279043 | Apoo | Mouse | cyclosporin A | increases expression | ISO | APOO (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of APOO mRNA | CTD | PMID:25562108 | Apoo | Mouse | dexamethasone | multiple interactions | ISO | APOO (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of APOO mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of APOO mRNA | CTD | PMID:28628672 | Apoo | Mouse | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of APOO mRNA | CTD | PMID:22206623 | Apoo | Mouse | glyphosate | increases methylation | ISO | Apoo (Rattus norvegicus) | 6480464 | Glyphosate results in increased methylation of APOO gene | CTD | PMID:31011160 | Apoo | Mouse | indometacin | multiple interactions | ISO | APOO (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of APOO mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of APOO mRNA | CTD | PMID:28628672 | Apoo | Mouse | ivermectin | decreases expression | ISO | APOO (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of APOO protein | CTD | PMID:32959892 | Apoo | Mouse | methapyrilene | increases methylation | ISO | APOO (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of APOO intron | CTD | PMID:30157460 | Apoo | Mouse | methimazole | increases expression | ISO | Apoo (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of APOO mRNA | CTD | PMID:30047161 | Apoo | Mouse | oxaliplatin | multiple interactions | ISO | Apoo (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of APOO mRNA | CTD | PMID:25729387 | Apoo | Mouse | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of APOO mRNA | CTD | PMID:17562736 | Apoo | Mouse | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of APOO mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of APOO mRNA | CTD | PMID:36331819 | Apoo | Mouse | perfluorooctanoic acid | multiple interactions | ISO | Apoo (Rattus norvegicus) | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of APOO mRNA | CTD | PMID:35163327 | Apoo | Mouse | perfluorooctanoic acid | increases expression | ISO | Apoo (Rattus norvegicus) | 6480464 | perfluorooctanoic acid results in increased expression of APOO protein | CTD | PMID:34958885 | Apoo | Mouse | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of APOO mRNA | CTD | PMID:23811191 | Apoo | Mouse | resveratrol | multiple interactions | ISO | APOO (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of APOO mRNA | CTD | PMID:23557933 | Apoo | Mouse | sodium arsenite | decreases expression | ISO | APOO (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of APOO mRNA | CTD | PMID:38568856 | Apoo | Mouse | sodium arsenite | increases expression | ISO | APOO (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of APOO mRNA | CTD | PMID:34032870 | Apoo | Mouse | sulfadimethoxine | increases expression | ISO | Apoo (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of APOO mRNA | CTD | PMID:30047161 | Apoo | Mouse | sulforaphane | increases expression | EXP | | 6480464 | sulforaphane results in increased expression of APOO mRNA | CTD | PMID:30529165 | Apoo | Mouse | sunitinib | decreases expression | ISO | APOO (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of APOO mRNA | CTD | PMID:31533062 | Apoo | Mouse | titanium dioxide | increases methylation | EXP | | 6480464 | titanium dioxide results in increased methylation of APOO gene and titanium dioxide results in increased methylation of APOO promoter | CTD | PMID:35295148 | Apoo | Mouse | topotecan | multiple interactions | ISO | Apoo (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of APOO mRNA | CTD | PMID:25729387 | Apoo | Mouse | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of APOO mRNA | CTD | PMID:33045310 | Apoo | Mouse | tungsten | increases expression | EXP | | 6480464 | Tungsten results in increased expression of APOO mRNA | CTD | PMID:30912803 | Apoo | Mouse | valproic acid | increases expression | ISO | APOO (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of APOO mRNA and Valproic Acid results in increased expression of APOO protein | CTD | PMID:29154799 and PMID:29501571 | Apoo | Mouse | valproic acid | affects expression | ISO | APOO (Homo sapiens) | 6480464 | Valproic Acid affects the expression of APOO mRNA | CTD | PMID:25979313 | Apoo | Mouse | valproic acid | decreases methylation | ISO | APOO (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of APOO gene | CTD | PMID:29501571 | Apoo | Mouse | vinclozolin | decreases methylation | ISO | Apoo (Rattus norvegicus) | 6480464 | vinclozolin results in decreased methylation of APOO gene | CTD | PMID:31682807 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