Saxo5 (stabilizer of axonemal microtubules 5) - Rat Genome Database

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Gene: Saxo5 (stabilizer of axonemal microtubules 5) Mus musculus
Analyze
Symbol: Saxo5
Name: stabilizer of axonemal microtubules 5
RGD ID: 1615813
MGI Page MGI
Description: Is expressed in ductus deferens; prostate gland; and testis. Orthologous to human SAXO5 (stabilizer of axonemal microtubules 5).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 1700019B03Rik; hypothetical protein LOC76406; RIKEN cDNA 1700019B03 gene; testis expressed 45; testis-expressed protein 45; Tex45; uncharacterized protein C19orf45 homolog; uncharacterized protein LOC76406
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3983,515,966 - 3,537,183 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl83,520,862 - 3,537,181 (+)EnsemblGRCm39 Ensembl
GRCm3883,466,713 - 3,487,183 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl83,470,862 - 3,487,181 (+)EnsemblGRCm38mm10GRCm38
MGSCv3783,470,862 - 3,487,178 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3683,470,862 - 3,487,181 (+)NCBIMGSCv36mm8
Celera83,696,734 - 3,713,152 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map81.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21677750   PMID:24194600   PMID:27357688  
PMID:27626380   PMID:38355793  


Genomics

Comparative Map Data
Saxo5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3983,515,966 - 3,537,183 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl83,520,862 - 3,537,181 (+)EnsemblGRCm39 Ensembl
GRCm3883,466,713 - 3,487,183 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl83,470,862 - 3,487,181 (+)EnsemblGRCm38mm10GRCm38
MGSCv3783,470,862 - 3,487,178 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3683,470,862 - 3,487,181 (+)NCBIMGSCv36mm8
Celera83,696,734 - 3,713,152 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map81.92NCBI
SAXO5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38197,497,548 - 7,508,450 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl197,492,976 - 7,508,450 (+)EnsemblGRCh38hg38GRCh38
GRCh37197,562,434 - 7,573,336 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36197,468,485 - 7,479,336 (+)NCBINCBI36Build 36hg18NCBI36
Celera197,434,951 - 7,445,845 (+)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef197,233,805 - 7,244,691 (+)NCBIHuRef
CHM1_1197,562,466 - 7,573,361 (+)NCBICHM1_1
T2T-CHM13v2.0197,498,219 - 7,509,163 (+)NCBIT2T-CHM13v2.0
Saxo5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8126,318,845 - 6,336,018 (+)NCBIGRCr8
mRatBN7.2121,520,983 - 1,538,127 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl121,521,014 - 1,538,118 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx122,191,775 - 2,202,436 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0122,815,341 - 2,826,003 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0121,587,372 - 1,598,026 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0122,016,035 - 2,033,140 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,016,058 - 2,033,112 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0124,179,781 - 4,196,186 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4122,676,818 - 2,687,753 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera123,383,615 - 3,394,513 (+)NCBICelera
Cytogenetic Map12p12NCBI
Saxo5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555631,703,416 - 1,745,996 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555631,723,768 - 1,729,831 (-)NCBIChiLan1.0ChiLan1.0
SAXO5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22012,169,095 - 12,180,981 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11911,287,227 - 11,298,197 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0196,788,323 - 6,799,578 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1197,647,908 - 7,657,380 (+)NCBIpanpan1.1PanPan1.1panPan2
SAXO5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12052,297,373 - 52,304,400 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2052,101,541 - 52,108,348 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02052,826,937 - 52,833,752 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2052,810,257 - 52,845,852 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12052,030,490 - 52,037,288 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02052,474,070 - 52,480,878 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02052,705,000 - 52,711,807 (+)NCBIUU_Cfam_GSD_1.0
Saxo5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118213,244,891 - 213,250,408 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365884,585,951 - 4,589,865 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365884,585,737 - 4,589,892 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SAXO5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl271,625,862 - 71,631,705 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1271,625,869 - 71,632,658 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2272,108,783 - 72,127,327 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SAXO5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.166,992,822 - 7,004,362 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl66,995,116 - 7,004,141 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666081864,000 - 883,654 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Saxo5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624828620,306 - 625,233 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624828618,820 - 625,239 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Saxo5
479 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:357
Count of miRNA genes:228
Interacting mature miRNAs:238
Transcripts:ENSMUST00000047265, ENSMUST00000159076, ENSMUST00000161680
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11533914Mts5_mmammary tumor susceptibility 5 (mouse)8130447432Mouse
13432571Scvg1_msubcutaneous vessel growth QTL 1 (mouse)8124751082Mouse
4140978Nilac5_mnicotine induced locomotor activity 5 (mouse)Not determined8131773288Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000047265   ⟹   ENSMUSP00000043586
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl83,520,862 - 3,537,178 (+)Ensembl
GRCm38.p6 Ensembl83,470,862 - 3,487,178 (+)Ensembl
Ensembl Acc Id: ENSMUST00000159076   ⟹   ENSMUSP00000123746
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl83,520,862 - 3,537,178 (+)Ensembl
GRCm38.p6 Ensembl83,470,862 - 3,487,178 (+)Ensembl
Ensembl Acc Id: ENSMUST00000161680   ⟹   ENSMUSP00000124916
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl83,525,849 - 3,537,181 (+)Ensembl
GRCm38.p6 Ensembl83,475,849 - 3,487,181 (+)Ensembl
RefSeq Acc Id: NM_029598   ⟹   NP_083874
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3983,520,862 - 3,537,178 (+)NCBI
GRCm3883,470,862 - 3,487,178 (+)NCBI
MGSCv3783,470,862 - 3,487,178 (+)RGD
Celera83,696,734 - 3,713,152 (+)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006508921   ⟹   XP_006508984
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3983,518,886 - 3,537,183 (+)NCBI
GRCm3883,468,886 - 3,487,183 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508922   ⟹   XP_006508985
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3983,518,886 - 3,537,183 (+)NCBI
GRCm3883,468,886 - 3,487,183 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508923   ⟹   XP_006508986
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3983,518,886 - 3,534,187 (+)NCBI
GRCm3883,468,886 - 3,484,187 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508924   ⟹   XP_006508987
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3983,518,886 - 3,537,017 (+)NCBI
GRCm3883,468,886 - 3,487,016 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508925   ⟹   XP_006508988
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3983,518,886 - 3,533,675 (+)NCBI
GRCm3883,468,886 - 3,483,675 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017313002   ⟹   XP_017168491
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3983,520,759 - 3,537,183 (+)NCBI
GRCm3883,470,765 - 3,487,183 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017313003   ⟹   XP_017168492
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3983,524,787 - 3,537,183 (+)NCBI
GRCm3883,474,789 - 3,487,183 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017313004   ⟹   XP_017168493
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3983,515,966 - 3,537,183 (+)NCBI
GRCm3883,466,713 - 3,487,183 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017313005   ⟹   XP_017168494
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3983,524,243 - 3,537,183 (+)NCBI
GRCm3883,474,243 - 3,487,183 (+)NCBI
Sequence:
RefSeq Acc Id: NP_083874   ⟸   NM_029598
- UniProtKB: G3XA23 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006508984   ⟸   XM_006508921
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006508985   ⟸   XM_006508922
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006508987   ⟸   XM_006508924
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006508986   ⟸   XM_006508923
- Peptide Label: isoform X4
- UniProtKB: Q80YS7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006508988   ⟸   XM_006508925
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_017168493   ⟸   XM_017313004
- Peptide Label: isoform X2
- UniProtKB: G3XA23 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017168491   ⟸   XM_017313002
- Peptide Label: isoform X2
- UniProtKB: G3XA23 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017168494   ⟸   XM_017313005
- Peptide Label: isoform X2
- UniProtKB: G3XA23 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017168492   ⟸   XM_017313003
- Peptide Label: isoform X2
- UniProtKB: G3XA23 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000123746   ⟸   ENSMUST00000159076
Ensembl Acc Id: ENSMUSP00000043586   ⟸   ENSMUST00000047265
Ensembl Acc Id: ENSMUSP00000124916   ⟸   ENSMUST00000161680

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3XA23-F1-model_v2 AlphaFold G3XA23 1-500 view protein structure

Promoters
RGD ID:8666317
Promoter ID:EPDNEW_M11190
Type:initiation region
Name:Tex45_1
Description:Mus musculus testis expressed 45 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3883,470,847 - 3,470,907EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1923656 AgrOrtholog
Ensembl Genes ENSMUSG00000040340 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000047265 ENTREZGENE
  ENSMUST00000047265.13 UniProtKB/TrEMBL
  ENSMUST00000159076 ENTREZGENE
  ENSMUST00000159076.8 UniProtKB/TrEMBL
  ENSMUST00000161680 ENTREZGENE
  ENSMUST00000161680.2 UniProtKB/TrEMBL
InterPro DUF4601 UniProtKB/TrEMBL
KEGG Report mmu:76406 UniProtKB/TrEMBL
MGD MGI:1923656 ENTREZGENE
NCBI Gene 76406 ENTREZGENE
PANTHER PTHR34828 UniProtKB/TrEMBL
  TESTIS-EXPRESSED PROTEIN 45 UniProtKB/TrEMBL
Pfam DUF4601 UniProtKB/TrEMBL
PhenoGen Saxo5 PhenoGen
UniProt G3XA23 ENTREZGENE, UniProtKB/TrEMBL
  Q80YS7 ENTREZGENE, UniProtKB/TrEMBL
  Q9DA72_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-05 Saxo5  stabilizer of axonemal microtubules 5  Tex45  testis expressed 45  Symbol and/or name updated 27372883 PROVISIONAL
2017-04-25 Tex45  testis expressed 45  1700019B03Rik  RIKEN cDNA 1700019B03 gene  Symbol and/or name change 5135510 APPROVED