KRT80 (keratin 80) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: KRT80 (keratin 80) Homo sapiens
Analyze
Symbol: KRT80
Name: keratin 80
RGD ID: 1606454
HGNC Page HGNC:27056
Description: Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Located in cytoplasm and intermediate filament.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CK-80; cytokeratin-80; K80; KB20; keratin 80, type II; keratin b20; keratin, type II cytoskeletal 80; keratin-80; type II keratin; type-II keratin Kb20
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381252,168,996 - 52,192,014 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1252,168,996 - 52,192,014 (-)EnsemblGRCh38hg38GRCh38
GRCh371252,562,780 - 52,585,798 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361250,849,047 - 50,872,051 (-)NCBINCBI36Build 36hg18NCBI36
Celera1251,365,224 - 51,388,227 (-)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1249,596,065 - 49,619,064 (-)NCBIHuRef
CHM1_11252,529,044 - 52,552,043 (-)NCBICHM1_1
T2T-CHM13v2.01252,132,581 - 52,155,594 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 95 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
KRT80Human(S)-nicotine increases expressionEXP 6480464Nicotine results in increased expression of KRT80 mRNACTDPMID:23825647
KRT80Human1-naphthyl isothiocyanate increases expressionISORGD:135917764804641-Naphthylisothiocyanate results in increased expression of KRT80 mRNACTDPMID:30723492
KRT80Human17beta-estradiol decreases expressionISORGD:16239316480464Estradiol results in decreased expression of KRT80 mRNACTDPMID:19484750
KRT80Human17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of KRT80 mRNACTDPMID:31614463
KRT80Human17beta-estradiol multiple interactionsEXP 6480464[Estradiol co-treated with TGFB1 protein] results in decreased expression of KRT80 mRNACTDPMID:30165855
KRT80Human2,3,7,8-tetrachlorodibenzodioxine increases expressionISORGD:16239316480464Tetrachlorodibenzodioxin results in increased expression of KRT80 mRNACTDPMID:19933214
KRT80Human2,3,7,8-tetrachlorodibenzodioxine increases expressionISORGD:13591776480464Tetrachlorodibenzodioxin results in increased expression of KRT80 mRNACTDPMID:33387578
KRT80Human2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of KRT80 mRNACTDPMID:23152189
KRT80Human2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:16239316480464Tetrachlorodibenzodioxin affects the expression of KRT80 mRNACTDPMID:21570461
KRT80Human2,3,7,8-Tetrachlorodibenzofuran increases expressionISORGD:135917764804642,3,7,8-tetrachlorodibenzofuran results in increased expression of KRT80 mRNACTDPMID:32109520
KRT80Human2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISORGD:162393164804642,2',4,4',5-brominated diphenyl ether affects the expression of KRT80 mRNACTDPMID:38648751
KRT80Human2,6-dimethoxyphenol multiple interactionsEXP 6480464[pyrogallol 1,3-dimethyl ether co-treated with Furaldehyde] results in decreased expression of and affects the localization more ...CTDPMID:38598786
KRT80Human2-hydroxypropanoic acid decreases expressionEXP 6480464Lactic Acid results in decreased expression of KRT80 mRNACTDPMID:30851411
KRT80Human4,4'-sulfonyldiphenol increases expressionISORGD:16239316480464bisphenol S results in increased expression of KRT80 mRNACTDPMID:30951980
KRT80Human4-hydroxyphenyl retinamide decreases expressionISORGD:16239316480464Fenretinide results in decreased expression of KRT80 mRNACTDPMID:28973697
KRT80Human7,12-dimethyltetraphene increases expressionEXP 64804649,10-Dimethyl-1,2-benzanthracene results in increased expression of KRT80 mRNACTDPMID:21527772
KRT80Humanactinomycin D increases expressionEXP 6480464Dactinomycin results in increased expression of KRT80 mRNACTDPMID:21527772
KRT80Humanaflatoxin B1 increases expressionEXP 6480464Aflatoxin B1 results in increased expression of KRT80 mRNA; Aflatoxin B1 results in increased expression more ...CTDPMID:21527772|PMID:22100608
KRT80HumanArchazolid B decreases expressionEXP 6480464archazolid B results in decreased expression of KRT80 mRNACTDPMID:25218289
KRT80Humanaristolochic acid A increases expressionEXP 6480464aristolochic acid I results in increased expression of KRT80 mRNA; aristolochic acid I results in more ...CTDPMID:33212167

1 to 20 of 95 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
KRT80Humanintermediate filament organization involved_inIBAMGI:1100845|MGI:1333768|MGI:96699|PANTHER:PTN002897426|UniProtKB:Q3SY84150520179 GO_CentralGO_REF:0000033
KRT80Humankeratinization involved_inIBAMGI:1100845|MGI:1333768|PANTHER:PTN002897426|UniProtKB:P35908150520179 GO_CentralGO_REF:0000033

Cellular Component
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
KRT80Humancytoplasm located_inIDA 150520179 PMID:20843789UniProtPMID:20843789
KRT80Humancytosol located_inIEAARBA:ARBA00029243150520179 UniProtGO_REF:0000117
KRT80Humancytosol located_inTAS 150520179 ReactomeReactome:R-HSA-6805546|Reactome:R-HSA-6805573|Reactome:R-HSA-6806610|Reactome:R-HSA-6806613|Reactome:R-HSA-6806629|Reactome:R-HSA-6809393|Reactome:R-HSA-6809663|Reactome:R-HSA-6810357|Reactome:R-HSA-6810937|Reactome:R-HSA-6811539|Reactome:R-HSA-6814298|Reactome:R-HSA-6814387|Reactome:R-HSA-6814734|Reactome:R-HSA-6814764|Reactome:R-HSA-8942224
KRT80Humandesmosome NOT|located_inIDA 150520179 PMID:20843789UniProtPMID:20843789
KRT80Humanintermediate filament located_inIEAUniProtKB-KW:KW-0403|UniProtKB-KW:KW-0416150520179 UniProtGO_REF:0000043
KRT80Humanintermediate filament located_inIDA 150520179 PMID:20843789UniProtPMID:20843789
KRT80Humanintermediate filament cytoskeleton located_inIDA 150520179 HPAGO_REF:0000052
KRT80Humankeratin filament located_inIEAInterPro:IPR003054150520179 InterProGO_REF:0000002
KRT80Humankeratin filament is_active_inIBAMGI:1861586|MGI:96698|MGI:96699|MGI:96702|PANTHER:PTN002897426|RGD:727894|UniProtKB:O43790|UniProtKB:P04264|UniProtKB:P13647|UniProtKB:P19013|UniProtKB:Q3SY84|UniProtKB:Q9NSB2|UniProtKB:Q9NSB4150520179 GO_CentralGO_REF:0000033
KRT80Humankeratin filament located_inNAS 150520179 PMID:26181054ComplexPortalPMID:26181054
1 to 10 of 10 rows

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
KRT80Humanprotein binding enablesIPIUniProtKB:O76011|UniProtKB:O76013-2|UniProtKB:O76015|UniProtKB:O95447|UniProtKB:P02533|UniProtKB:P08727|UniProtKB:P08779|UniProtKB:P19012|UniProtKB:P25791-3|UniProtKB:P35900|UniProtKB:Q14525|UniProtKB:Q14532|UniProtKB:Q15323|UniProtKB:Q2M2I5|UniProtKB:Q7Z3Y7|UniProtKB:Q92764|UniProtKB:Q9BRX5|UniProtKB:Q9NX04|UniProtKB:Q9UNS2150520179 PMID:32296183IntActPMID:32296183
KRT80Humanprotein binding enablesIPIUniProtKB:P19012|UniProtKB:P35900|UniProtKB:P50222150520179 PMID:25416956IntActPMID:25416956
KRT80Humanstructural constituent of skin epidermis enablesIBAMGI:96699|MGI:96700|PANTHER:PTN002897426|UniProtKB:P04264|UniProtKB:P35908150520179 GO_CentralGO_REF:0000033


#
Reference Title
Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12477932   PMID:15737194   PMID:16831889   PMID:17207965   PMID:20843789   PMID:21145461   PMID:21654808   PMID:21800051   PMID:21873635   PMID:24465473   PMID:24711643   PMID:25324306  
PMID:25416956   PMID:25476789   PMID:26181054   PMID:26618866   PMID:27591049   PMID:28007894   PMID:28977666   PMID:29507755   PMID:29563501   PMID:29844126   PMID:29845934   PMID:29911972  
PMID:30262880   PMID:30561431   PMID:30737378   PMID:31073170   PMID:31324722   PMID:32296183   PMID:32687490   PMID:32780723   PMID:32989256   PMID:33961781   PMID:34445801   PMID:34537242  
PMID:35013556   PMID:35474131   PMID:35748914   PMID:35831895   PMID:35864588   PMID:35944360   PMID:36057605   PMID:36217029   PMID:36526897   PMID:36604567   PMID:36949045   PMID:37120454  
PMID:37129345   PMID:37211956   PMID:37314216   PMID:37782686   PMID:38241178  



KRT80
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381252,168,996 - 52,192,014 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1252,168,996 - 52,192,014 (-)EnsemblGRCh38hg38GRCh38
GRCh371252,562,780 - 52,585,798 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361250,849,047 - 50,872,051 (-)NCBINCBI36Build 36hg18NCBI36
Celera1251,365,224 - 51,388,227 (-)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1249,596,065 - 49,619,064 (-)NCBIHuRef
CHM1_11252,529,044 - 52,552,043 (-)NCBICHM1_1
T2T-CHM13v2.01252,132,581 - 52,155,594 (-)NCBIT2T-CHM13v2.0
Krt80
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915101,246,196 - 101,268,043 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15101,245,325 - 101,268,043 (-)EnsemblGRCm39 Ensembl
GRCm3815101,348,315 - 101,370,162 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15101,347,444 - 101,370,162 (-)EnsemblGRCm38mm10GRCm38
MGSCv3715101,180,002 - 101,200,556 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3615101,175,481 - 101,198,366 (-)NCBIMGSCv36mm8
Celera15103,497,804 - 103,518,340 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.78NCBI
Krt80
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87134,341,951 - 134,363,872 (-)NCBIGRCr8
mRatBN7.27132,463,216 - 132,485,134 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7132,463,218 - 132,485,508 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7134,266,548 - 134,286,776 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07136,496,053 - 136,516,283 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07136,405,779 - 136,426,014 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07142,995,715 - 143,015,932 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7142,994,119 - 143,016,040 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07140,796,567 - 140,816,784 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47140,096,091 - 140,115,890 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17140,172,527 - 140,192,327 (-)NCBI
Celera7128,929,953 - 128,950,211 (-)NCBICelera
Cytogenetic Map7q36NCBI
Krt80
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555472,511,235 - 2,531,630 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555472,511,235 - 2,531,631 (-)NCBIChiLan1.0ChiLan1.0
KRT80
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21042,003,383 - 42,026,325 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11242,000,161 - 42,023,088 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01236,561,484 - 36,593,887 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11237,348,186 - 37,371,250 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1237,348,186 - 37,371,250 (+)Ensemblpanpan1.1panPan2
KRT80
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1272,862,179 - 2,883,727 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl272,860,735 - 2,884,680 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2743,371,083 - 43,392,776 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0272,860,345 - 2,882,050 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl272,859,091 - 2,882,086 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1272,877,103 - 2,898,785 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0272,863,095 - 2,884,772 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02743,769,282 - 43,790,971 (-)NCBIUU_Cfam_GSD_1.0
Krt80
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494563,565,725 - 63,587,967 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365129,576,851 - 9,599,037 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365129,576,867 - 9,599,050 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KRT80
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl517,482,460 - 17,508,513 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1517,482,454 - 17,506,462 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KRT80
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11148,316,539 - 48,339,552 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1148,315,946 - 48,338,923 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037197,752,635 - 197,775,923 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Krt80
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624816177,066 - 197,698 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624816176,804 - 197,612 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in KRT80
55 total Variants

1 to 10 of 64 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33
pathogenic
GRCh38/hg38 12q13.12-13.13(chr12:50633888-52851909)x1 copy number loss See cases [RCV000140716] Chr12:50633888..52851909 [GRCh38]
Chr12:51027671..53245693 [GRCh37]
Chr12:49313938..51531960 [NCBI36]
Chr12:12q13.12-13.13
pathogenic
GRCh38/hg38 12q13.12-13.13(chr12:50122359-53248460)x1 copy number loss See cases [RCV000142033] Chr12:50122359..53248460 [GRCh38]
Chr12:50516142..53642244 [GRCh37]
Chr12:48802409..51928511 [NCBI36]
Chr12:12q13.12-13.13
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:1-133851895)x3 copy number gain See cases [RCV000258805] Chr12:1..133851895 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic|likely pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902)x3 copy number gain See cases [RCV000510482] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902) copy number gain See cases [RCV000511643] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
NM_182507.3(KRT80):c.134G>C (p.Ser45Thr) single nucleotide variant not specified [RCV004290041] Chr12:52191769 [GRCh38]
Chr12:52585553 [GRCh37]
Chr12:12q13.13
uncertain significance
NM_182507.3(KRT80):c.273T>G (p.Asn91Lys) single nucleotide variant not specified [RCV004309626] Chr12:52191630 [GRCh38]
Chr12:52585414 [GRCh37]
Chr12:12q13.13
uncertain significance
NC_000012.11:g.26370251_54361538inv inversion not specified [RCV000714265] Chr12:26370251..54361538 [GRCh37]
Chr12:12p12.1-q13.13
uncertain significance
GRCh37/hg19 12p13.33-q24.33(chr12:191619-133777645)x3 copy number gain not provided [RCV000750246] Chr12:191619..133777645 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
1 to 10 of 64 rows

Predicted Target Of
Summary Value
Count of predictions:3321
Count of miRNA genes:850
Interacting mature miRNAs:1003
Transcripts:ENST00000313234, ENST00000394815, ENST00000466011
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

SHGC-156072  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371252,581,409 - 52,581,695UniSTSGRCh37
Build 361250,867,676 - 50,867,962RGDNCBI36
Celera1251,383,852 - 51,384,138RGD
Cytogenetic Map12q13.13UniSTS
HuRef1249,614,689 - 49,614,975UniSTS
TNG Radiation Hybrid Map1224301.0UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
1198 2407 2778 2223 4641 1694 2313 5 597 1378 438 2219 6676 5881 43 3436 1 845 1734 1604 172



Ensembl Acc Id: ENST00000313234   ⟹   ENSP00000369361
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1252,168,996 - 52,192,000 (-)Ensembl
Ensembl Acc Id: ENST00000394815   ⟹   ENSP00000378292
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1252,168,996 - 52,192,014 (-)Ensembl
Ensembl Acc Id: ENST00000466011
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1252,169,523 - 52,185,749 (-)Ensembl
RefSeq Acc Id: NM_001081492   ⟹   NP_001074961
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381252,168,996 - 52,192,014 (-)NCBI
GRCh371252,562,780 - 52,585,798 (-)NCBI
Build 361250,849,047 - 50,872,051 (-)NCBI Archive
Celera1251,365,224 - 51,388,227 (-)RGD
HuRef1249,596,065 - 49,619,064 (-)RGD
CHM1_11252,529,044 - 52,552,043 (-)NCBI
T2T-CHM13v2.01252,132,581 - 52,155,594 (-)NCBI
Sequence:
RefSeq Acc Id: NM_182507   ⟹   NP_872313
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381252,168,996 - 52,192,014 (-)NCBI
GRCh371252,562,780 - 52,585,798 (-)NCBI
Build 361250,849,047 - 50,872,051 (-)NCBI Archive
Celera1251,365,224 - 51,388,227 (-)RGD
HuRef1249,596,065 - 49,619,064 (-)RGD
CHM1_11252,529,044 - 52,552,043 (-)NCBI
T2T-CHM13v2.01252,132,581 - 52,155,594 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005268676   ⟹   XP_005268733
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381252,168,996 - 52,185,749 (-)NCBI
GRCh371252,562,780 - 52,585,798 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054371193   ⟹   XP_054227168
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01252,132,581 - 52,149,278 (-)NCBI
RefSeq Acc Id: NP_001074961   ⟸   NM_001081492
- Peptide Label: isoform K80.1
- UniProtKB: Q6KB66 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_872313   ⟸   NM_182507
- Peptide Label: isoform K80
- UniProtKB: Q6P1A5 (UniProtKB/Swiss-Prot),   Q7Z3Q0 (UniProtKB/Swiss-Prot),   Q6KB66 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005268733   ⟸   XM_005268676
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSP00000369361   ⟸   ENST00000313234
Ensembl Acc Id: ENSP00000378292   ⟸   ENST00000394815
IF rod

Name Modeler Protein Id AA Range Protein Structure
AF-Q6KB66-F1-model_v2 AlphaFold Q6KB66 1-452 view protein structure

RGD ID:6790183
Promoter ID:HG_KWN:15684
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3
Transcripts:OTTHUMT00000316758
Position:
Human AssemblyChrPosition (strand)Source
Build 361250,865,821 - 50,866,321 (-)MPROMDB
RGD ID:6790184
Promoter ID:HG_KWN:15685
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3
Transcripts:NM_001081492,   NM_182507
Position:
Human AssemblyChrPosition (strand)Source
Build 361250,871,771 - 50,872,271 (-)MPROMDB
RGD ID:7223987
Promoter ID:EPDNEW_H17739
Type:initiation region
Name:KRT80_1
Description:keratin 80
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H17740  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381252,192,014 - 52,192,074EPDNEW
RGD ID:7223989
Promoter ID:EPDNEW_H17740
Type:initiation region
Name:KRT80_2
Description:keratin 80
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H17739  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381252,192,305 - 52,192,365EPDNEW


1 to 31 of 31 rows
Database
Acc Id
Source(s)
COSMIC KRT80 COSMIC
Ensembl Genes ENSG00000167767 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000313234 ENTREZGENE
  ENST00000313234.9 UniProtKB/Swiss-Prot
  ENST00000394815 ENTREZGENE
  ENST00000394815.3 UniProtKB/Swiss-Prot
  ENST00000466011 ENTREZGENE
Gene3D-CATH 1.20.5.170 UniProtKB/Swiss-Prot
  Single helix bin UniProtKB/Swiss-Prot
  Vasodilator-stimulated phosphoprotein UniProtKB/Swiss-Prot
GTEx ENSG00000167767 GTEx
HGNC ID HGNC:27056 ENTREZGENE
Human Proteome Map KRT80 Human Proteome Map
InterPro IF_rod_dom UniProtKB/Swiss-Prot
  Keratin_II UniProtKB/Swiss-Prot
KEGG Report hsa:144501 UniProtKB/Swiss-Prot
NCBI Gene 144501 ENTREZGENE
OMIM 611161 OMIM
PANTHER GATA-TYPE DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
  KERATIN, TYPE II CYTOSKELETAL 80 UniProtKB/Swiss-Prot
Pfam Filament UniProtKB/Swiss-Prot
PharmGKB PA147357831 PharmGKB
PRINTS TYPE2KERATIN UniProtKB/Swiss-Prot
PROSITE IF_ROD_2 UniProtKB/Swiss-Prot
SMART Filament UniProtKB/Swiss-Prot
Superfamily-SCOP Intermediate filament protein, coiled coil region UniProtKB/Swiss-Prot
UniProt K2C80_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q6P1A5 ENTREZGENE
  Q7Z3Q0 ENTREZGENE
UniProt Secondary Q6P1A5 UniProtKB/Swiss-Prot
  Q7Z3Q0 UniProtKB/Swiss-Prot
1 to 31 of 31 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-14 KRT80  keratin 80    keratin 80, type II  Symbol and/or name change 5135510 APPROVED
2015-01-27 KRT80  keratin 80, type II    keratin 80  Symbol and/or name change 5135510 APPROVED