GSTCD (glutathione S-transferase C-terminal domain containing) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: GSTCD (glutathione S-transferase C-terminal domain containing) Homo sapiens
Analyze
Symbol: GSTCD
Name: glutathione S-transferase C-terminal domain containing
RGD ID: 1602688
HGNC Page HGNC:25806
Description: Located in cytoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DKFZp686I10174; FLJ13273; glutathione S-transferase C-terminal domain-containing protein; glutathione S-transferase, C-terminal domain containing
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384105,708,784 - 105,847,725 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4105,708,778 - 105,847,725 (+)EnsemblGRCh38hg38GRCh38
GRCh374106,629,941 - 106,768,882 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364106,849,390 - 106,988,327 (+)NCBINCBI36Build 36hg18NCBI36
Celera4103,929,094 - 104,068,013 (+)NCBICelera
Cytogenetic Map4q24NCBI
HuRef4102,364,471 - 102,503,550 (+)NCBIHuRef
CHM1_14106,606,735 - 106,745,677 (+)NCBICHM1_1
T2T-CHM13v2.04109,019,919 - 109,158,852 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IDA,IEA)
extracellular exosome  (HDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8125298   PMID:12477932   PMID:14702039   PMID:19056867   PMID:20010834   PMID:20010835   PMID:20332099   PMID:21873635   PMID:21965014   PMID:23284291   PMID:23455924   PMID:24023788  
PMID:24058608   PMID:24915237   PMID:25814554   PMID:26186194   PMID:26673895   PMID:26760575   PMID:28514442   PMID:31370853   PMID:31617661   PMID:33961781   PMID:35384245   PMID:35831314  
PMID:36215168  


Genomics

Comparative Map Data
GSTCD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384105,708,784 - 105,847,725 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4105,708,778 - 105,847,725 (+)EnsemblGRCh38hg38GRCh38
GRCh374106,629,941 - 106,768,882 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364106,849,390 - 106,988,327 (+)NCBINCBI36Build 36hg18NCBI36
Celera4103,929,094 - 104,068,013 (+)NCBICelera
Cytogenetic Map4q24NCBI
HuRef4102,364,471 - 102,503,550 (+)NCBIHuRef
CHM1_14106,606,735 - 106,745,677 (+)NCBICHM1_1
T2T-CHM13v2.04109,019,919 - 109,158,852 (+)NCBIT2T-CHM13v2.0
Gstcd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393132,687,511 - 132,797,800 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3132,687,513 - 132,797,794 (-)EnsemblGRCm39 Ensembl
GRCm383132,981,750 - 133,092,039 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3132,981,752 - 133,092,033 (-)EnsemblGRCm38mm10GRCm38
MGSCv373132,645,514 - 132,754,704 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363132,919,856 - 133,029,046 (-)NCBIMGSCv36mm8
Celera3139,406,859 - 139,516,166 (-)NCBICelera
Cytogenetic Map3G3NCBI
cM Map361.54NCBI
Gstcd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82224,173,764 - 224,268,743 (-)NCBIGRCr8
mRatBN7.22221,499,732 - 221,591,888 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2221,499,083 - 221,591,857 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2229,157,701 - 229,249,802 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02227,057,394 - 227,149,480 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02221,915,044 - 222,007,147 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02238,109,758 - 238,253,326 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2238,109,490 - 238,253,287 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02256,647,193 - 256,790,462 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42230,514,129 - 230,610,809 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12230,502,132 - 230,597,223 (-)NCBI
Celera2213,731,814 - 213,824,499 (-)NCBICelera
Cytogenetic Map2q43NCBI
Gstcd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554963,444,310 - 3,565,414 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554963,447,400 - 3,564,540 (-)NCBIChiLan1.0ChiLan1.0
GSTCD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23103,786,026 - 103,935,523 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14104,089,502 - 104,230,274 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0498,177,114 - 98,315,988 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14108,786,829 - 108,925,618 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4108,786,838 - 108,925,618 (+)Ensemblpanpan1.1panPan2
GSTCD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13226,540,237 - 26,665,649 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3226,540,931 - 26,663,260 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3215,360,982 - 15,486,180 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03226,771,037 - 26,897,517 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3226,771,373 - 26,897,426 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13226,767,811 - 26,893,964 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03226,513,698 - 26,638,836 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03213,223,757 - 13,349,014 (-)NCBIUU_Cfam_GSD_1.0
Gstcd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530114,492,983 - 14,520,741 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049368141,210,256 - 1,237,883 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GSTCD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8115,902,994 - 116,031,862 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18115,902,995 - 116,031,876 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28124,317,477 - 124,437,200 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GSTCD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1753,750,836 - 53,881,057 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl753,750,628 - 53,883,001 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603732,369,687 - 32,501,594 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gstcd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248302,971,738 - 3,100,491 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248302,982,971 - 3,100,486 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GSTCD
21 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 4q22.2-32.3(chr4:92913386-165299707)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051775]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051775]|See cases [RCV000051775] Chr4:92913386..165299707 [GRCh38]
Chr4:93834537..166220859 [GRCh37]
Chr4:94053560..166440309 [NCBI36]
Chr4:4q22.2-32.3		 pathogenic
GRCh38/hg38 4q22.3-28.3(chr4:96092893-136410207)x3 copy number gain See cases [RCV000051776] Chr4:96092893..136410207 [GRCh38]
Chr4:97014044..137331362 [GRCh37]
Chr4:97233067..137550812 [NCBI36]
Chr4:4q22.3-28.3		 pathogenic
GRCh38/hg38 4q24-25(chr4:105778347-110206873)x3 copy number gain See cases [RCV000051777] Chr4:105778347..110206873 [GRCh38]
Chr4:106699504..111128029 [GRCh37]
Chr4:106918953..111347478 [NCBI36]
Chr4:4q24-25		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:12440-190904441)x3 copy number gain See cases [RCV000446653] Chr4:12440..190904441 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473) copy number gain See cases [RCV000510453] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4q22.1-35.2(chr4:93071152-190957473)x3 copy number gain See cases [RCV000510970] Chr4:93071152..190957473 [GRCh37]
Chr4:4q22.1-35.2		 pathogenic
NM_001370181.1(GSTCD):c.296A>G (p.Asn99Ser) single nucleotide variant Inborn genetic diseases [RCV003264481] Chr4:105717909 [GRCh38]
Chr4:106639066 [GRCh37]
Chr4:4q24		 uncertain significance
NM_001370181.1(GSTCD):c.1547G>T (p.Cys516Phe) single nucleotide variant Inborn genetic diseases [RCV003275211] Chr4:105834477 [GRCh38]
Chr4:106755634 [GRCh37]
Chr4:4q24		 uncertain significance
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473)x3 copy number gain See cases [RCV000512241] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4q24(chr4:106507186-106882078)x3 copy number gain not provided [RCV000682441] Chr4:106507186..106882078 [GRCh37]
Chr4:4q24		 uncertain significance
GRCh37/hg19 4q24-25(chr4:106582279-108557118)x1 copy number loss not provided [RCV000682442] Chr4:106582279..108557118 [GRCh37]
Chr4:4q24-25		 uncertain significance
GRCh37/hg19 4q24(chr4:106631903-106769321)x1 copy number loss not provided [RCV000682443] Chr4:106631903..106769321 [GRCh37]
Chr4:4q24		 uncertain significance
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190915650)x3 copy number gain not provided [RCV000743155] Chr4:49450..190915650 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4q24-25(chr4:105039193-110409978)x3 copy number gain not provided [RCV000743885] Chr4:105039193..110409978 [GRCh37]
Chr4:4q24-25		 pathogenic
GRCh37/hg19 4q24(chr4:106708469-106715489)x1 copy number loss not provided [RCV000743888] Chr4:106708469..106715489 [GRCh37]
Chr4:4q24		 benign
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190963766)x3 copy number gain not provided [RCV000743156] Chr4:49450..190963766 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:11525-191028879)x3 copy number gain not provided [RCV000743147] Chr4:11525..191028879 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4q24(chr4:106262887-106663541)x3 copy number gain not provided [RCV000847321] Chr4:106262887..106663541 [GRCh37]
Chr4:4q24		 uncertain significance
NM_001370181.1(GSTCD):c.176A>G (p.Asp59Gly) single nucleotide variant Inborn genetic diseases [RCV003252114] Chr4:105717789 [GRCh38]
Chr4:106638946 [GRCh37]
Chr4:4q24		 uncertain significance
GRCh37/hg19 4q12-31.21(chr4:52866944-143582507)x3 copy number gain not provided [RCV001827738] Chr4:52866944..143582507 [GRCh37]
Chr4:4q12-31.21		 pathogenic
GRCh37/hg19 4q24-31.21(chr4:104715235-145252595) copy number gain not specified [RCV002053446] Chr4:104715235..145252595 [GRCh37]
Chr4:4q24-31.21		 pathogenic
GRCh37/hg19 4q22.3-25(chr4:95490755-109977216)x3 copy number gain not provided [RCV001827745] Chr4:95490755..109977216 [GRCh37]
Chr4:4q22.3-25		 likely pathogenic
NM_001370181.1(GSTCD):c.511A>G (p.Thr171Ala) single nucleotide variant Inborn genetic diseases [RCV002968924] Chr4:105719144 [GRCh38]
Chr4:106640301 [GRCh37]
Chr4:4q24		 likely benign
NM_001370181.1(GSTCD):c.143T>C (p.Ile48Thr) single nucleotide variant Inborn genetic diseases [RCV002906006] Chr4:105717756 [GRCh38]
Chr4:106638913 [GRCh37]
Chr4:4q24		 uncertain significance
NM_001370181.1(GSTCD):c.1652A>G (p.Asn551Ser) single nucleotide variant Inborn genetic diseases [RCV002734359] Chr4:105834582 [GRCh38]
Chr4:106755739 [GRCh37]
Chr4:4q24		 uncertain significance
NM_001370181.1(GSTCD):c.1390C>T (p.Pro464Ser) single nucleotide variant Inborn genetic diseases [RCV002781822] Chr4:105823264 [GRCh38]
Chr4:106744421 [GRCh37]
Chr4:4q24		 uncertain significance
NM_001370181.1(GSTCD):c.1453A>G (p.Ser485Gly) single nucleotide variant Inborn genetic diseases [RCV002887614] Chr4:105825723 [GRCh38]
Chr4:106746880 [GRCh37]
Chr4:4q24		 uncertain significance
NM_001370181.1(GSTCD):c.557C>T (p.Pro186Leu) single nucleotide variant Inborn genetic diseases [RCV002799835] Chr4:105719190 [GRCh38]
Chr4:106640347 [GRCh37]
Chr4:4q24		 uncertain significance
NM_001370181.1(GSTCD):c.373G>C (p.Glu125Gln) single nucleotide variant Inborn genetic diseases [RCV003006642] Chr4:105717986 [GRCh38]
Chr4:106639143 [GRCh37]
Chr4:4q24		 uncertain significance
NC_000004.11:g.(?_101947022)_(107268849_?)dup duplication not provided [RCV003154901] Chr4:101947022..107268849 [GRCh37]
Chr4:4q24		 uncertain significance
NM_001370181.1(GSTCD):c.1088A>G (p.Glu363Gly) single nucleotide variant Inborn genetic diseases [RCV003197041] Chr4:105726772 [GRCh38]
Chr4:106647929 [GRCh37]
Chr4:4q24		 uncertain significance
NM_001370181.1(GSTCD):c.1646A>G (p.Lys549Arg) single nucleotide variant Inborn genetic diseases [RCV003183196] Chr4:105834576 [GRCh38]
Chr4:106755733 [GRCh37]
Chr4:4q24		 uncertain significance
NM_001370181.1(GSTCD):c.1874A>G (p.Asn625Ser) single nucleotide variant Inborn genetic diseases [RCV003174272] Chr4:105845549 [GRCh38]
Chr4:106766706 [GRCh37]
Chr4:4q24		 uncertain significance
NM_001370181.1(GSTCD):c.599T>G (p.Leu200Arg) single nucleotide variant Inborn genetic diseases [RCV003206215] Chr4:105719232 [GRCh38]
Chr4:106640389 [GRCh37]
Chr4:4q24		 uncertain significance
NM_001370181.1(GSTCD):c.586C>T (p.Arg196Cys) single nucleotide variant Inborn genetic diseases [RCV003202971] Chr4:105719219 [GRCh38]
Chr4:106640376 [GRCh37]
Chr4:4q24		 uncertain significance
NM_001370181.1(GSTCD):c.565G>A (p.Val189Met) single nucleotide variant Inborn genetic diseases [RCV003344553] Chr4:105719198 [GRCh38]
Chr4:106640355 [GRCh37]
Chr4:4q24		 uncertain significance
NM_001370181.1(GSTCD):c.712G>A (p.Glu238Lys) single nucleotide variant Inborn genetic diseases [RCV003350986] Chr4:105719345 [GRCh38]
Chr4:106640502 [GRCh37]
Chr4:4q24		 uncertain significance
NM_001370181.1(GSTCD):c.1167G>A (p.Met389Ile) single nucleotide variant Inborn genetic diseases [RCV003354012] Chr4:105729426 [GRCh38]
Chr4:106650583 [GRCh37]
Chr4:4q24		 uncertain significance
NM_001370181.1(GSTCD):c.814C>G (p.Pro272Ala) single nucleotide variant Inborn genetic diseases [RCV003347283] Chr4:105719447 [GRCh38]
Chr4:106640604 [GRCh37]
Chr4:4q24		 uncertain significance
GRCh37/hg19 4q24-35.2(chr4:101203509-190957473)x3 copy number gain not specified [RCV003986496] Chr4:101203509..190957473 [GRCh37]
Chr4:4q24-35.2		 pathogenic
GRCh37/hg19 4q23-24(chr4:99355670-107274288)x1 copy number loss not specified [RCV003986486] Chr4:99355670..107274288 [GRCh37]
Chr4:4q23-24		 pathogenic
GRCh37/hg19 4q23-25(chr4:100172302-107880077)x1 copy number loss not specified [RCV003986501] Chr4:100172302..107880077 [GRCh37]
Chr4:4q23-25		 pathogenic
GRCh37/hg19 4p12-q35.2(chr4:45455621-191003541)x3 copy number gain not provided [RCV003885507] Chr4:45455621..191003541 [GRCh37]
Chr4:4p12-q35.2		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3477
Count of miRNA genes:940
Interacting mature miRNAs:1058
Transcripts:ENST00000360505, ENST00000394728, ENST00000394730, ENST00000484843, ENST00000503409, ENST00000507281, ENST00000509336, ENST00000510865, ENST00000512828, ENST00000515255, ENST00000515279
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-37278  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374106,687,572 - 106,687,697UniSTSGRCh37
Build 364106,907,021 - 106,907,146RGDNCBI36
Celera4103,986,713 - 103,986,838RGD
Cytogenetic Map4q24UniSTS
HuRef4102,422,070 - 102,422,195UniSTS
GeneMap99-G3 RH Map46124.0UniSTS
RH120440  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374106,698,026 - 106,698,354UniSTSGRCh37
Build 364106,917,475 - 106,917,803RGDNCBI36
Celera4103,997,151 - 103,997,479RGD
Cytogenetic Map4q24UniSTS
HuRef4102,432,508 - 102,432,836UniSTS
TNG Radiation Hybrid Map464764.0UniSTS
SHGC-50459  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374106,687,334 - 106,687,668UniSTSGRCh37
Build 364106,906,783 - 106,907,117RGDNCBI36
Celera4103,986,475 - 103,986,809RGD
Cytogenetic Map4q24UniSTS
HuRef4102,421,832 - 102,422,166UniSTS
TNG Radiation Hybrid Map464774.0UniSTS
STS-N32085  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374106,768,642 - 106,768,779UniSTSGRCh37
Build 364106,988,091 - 106,988,228RGDNCBI36
Celera4104,067,773 - 104,067,910RGD
Cytogenetic Map4q24UniSTS
HuRef4102,503,310 - 102,503,447UniSTS
TNG Radiation Hybrid Map464880.0UniSTS
GeneMap99-GB4 RH Map4506.26UniSTS
NCBI RH Map41175.8UniSTS
D4S877  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374106,673,463 - 106,673,669UniSTSGRCh37
Build 364106,892,912 - 106,893,118RGDNCBI36
Celera4103,972,610 - 103,972,816RGD
Cytogenetic Map4q24UniSTS
HuRef4102,407,982 - 102,408,188UniSTS
TNG Radiation Hybrid Map464874.0UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 99 4 32 20 482 22 220 43 104 56 281 178 6 1 2
Low 2339 2223 1629 549 892 388 4116 1975 3564 355 1176 1435 168 1 1204 2766 4 2
Below cutoff 1 761 65 55 574 55 21 179 66 7 3 21

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001031720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001370181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_024751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011532248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011532249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011532252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047416179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054350842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054350843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054350844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054350845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008487031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_938771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC008243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC105391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK023335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK225563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK292355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC032942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX648355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000360505   ⟹   ENSP00000353695
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl4105,710,810 - 105,845,754 (+)Ensembl
RefSeq Acc Id: ENST00000394728   ⟹   ENSP00000378216
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl4105,712,511 - 105,845,978 (+)Ensembl
RefSeq Acc Id: ENST00000394730   ⟹   ENSP00000378218
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl4105,708,784 - 105,847,725 (+)Ensembl
RefSeq Acc Id: ENST00000484843
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl4105,708,787 - 105,823,690 (+)Ensembl
RefSeq Acc Id: ENST00000503409
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl4105,717,626 - 105,719,559 (+)Ensembl
RefSeq Acc Id: ENST00000507281   ⟹   ENSP00000422858
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl4105,708,787 - 105,761,885 (+)Ensembl
RefSeq Acc Id: ENST00000509336   ⟹   ENSP00000423779
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl4105,710,846 - 105,719,135 (+)Ensembl
RefSeq Acc Id: ENST00000510865   ⟹   ENSP00000423792
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl4105,710,813 - 105,719,133 (+)Ensembl
RefSeq Acc Id: ENST00000512828   ⟹   ENSP00000423639
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl4105,708,778 - 105,717,735 (+)Ensembl
RefSeq Acc Id: ENST00000515255
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl4105,708,784 - 105,845,709 (+)Ensembl
RefSeq Acc Id: ENST00000515279   ⟹   ENSP00000422354
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl4105,708,784 - 105,847,725 (+)Ensembl
RefSeq Acc Id: NM_001031720   ⟹   NP_001026890
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh384105,710,813 - 105,847,725 (+)NCBI
GRCh374106,629,935 - 106,768,882 (+)NCBI
Build 364106,851,419 - 106,986,360 (+)NCBI Archive
Celera4103,929,094 - 104,068,013 (+)RGD
HuRef4102,364,471 - 102,503,550 (+)RGD
CHM1_14106,608,763 - 106,745,677 (+)NCBI
T2T-CHM13v2.04109,021,958 - 109,158,852 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001370181   ⟹   NP_001357110
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh384105,708,784 - 105,847,725 (+)NCBI
T2T-CHM13v2.04109,019,925 - 109,158,852 (+)NCBI
Sequence:
RefSeq Acc Id: NM_024751   ⟹   NP_079027
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh384105,708,784 - 105,847,725 (+)NCBI
GRCh374106,629,935 - 106,768,882 (+)NCBI
Build 364106,849,390 - 106,988,327 (+)NCBI Archive
Celera4103,929,094 - 104,068,013 (+)RGD
HuRef4102,364,471 - 102,503,550 (+)RGD
CHM1_14106,606,735 - 106,745,677 (+)NCBI
T2T-CHM13v2.04109,019,925 - 109,158,852 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011532248   ⟹   XP_011530550
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh384105,710,813 - 105,847,725 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011532249   ⟹   XP_011530551
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh384105,710,813 - 105,847,725 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011532252   ⟹   XP_011530554
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh384105,708,784 - 105,847,725 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047416179   ⟹   XP_047272135
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh384105,708,784 - 105,847,725 (+)NCBI
RefSeq Acc Id: XM_054350842   ⟹   XP_054206817
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.04109,021,746 - 109,158,852 (+)NCBI
RefSeq Acc Id: XM_054350843   ⟹   XP_054206818
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.04109,021,990 - 109,158,852 (+)NCBI
RefSeq Acc Id: XM_054350844   ⟹   XP_054206819
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.04109,019,919 - 109,158,852 (+)NCBI
RefSeq Acc Id: XM_054350845   ⟹   XP_054206820
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.04109,019,934 - 109,158,852 (+)NCBI
RefSeq Acc Id: XR_008487031
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.04109,019,925 - 109,145,676 (+)NCBI
RefSeq Acc Id: XR_938771
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh384105,708,784 - 105,834,549 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_079027   ⟸   NM_024751
- Peptide Label: isoform 2
- UniProtKB: Q8NEC7 (UniProtKB/Swiss-Prot),   B7Z8J7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001026890   ⟸   NM_001031720
- Peptide Label: isoform 1
- UniProtKB: H9KV97 (UniProtKB/Swiss-Prot),   A8MVD3 (UniProtKB/Swiss-Prot),   A8K8J0 (UniProtKB/Swiss-Prot),   Q9H8S3 (UniProtKB/Swiss-Prot),   Q8NEC7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011530554   ⟸   XM_011532252
- Peptide Label: isoform X1
- UniProtKB: H9KV97 (UniProtKB/Swiss-Prot),   A8MVD3 (UniProtKB/Swiss-Prot),   A8K8J0 (UniProtKB/Swiss-Prot),   Q9H8S3 (UniProtKB/Swiss-Prot),   Q8NEC7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011530551   ⟸   XM_011532249
- Peptide Label: isoform X1
- UniProtKB: H9KV97 (UniProtKB/Swiss-Prot),   A8MVD3 (UniProtKB/Swiss-Prot),   A8K8J0 (UniProtKB/Swiss-Prot),   Q9H8S3 (UniProtKB/Swiss-Prot),   Q8NEC7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011530550   ⟸   XM_011532248
- Peptide Label: isoform X1
- UniProtKB: H9KV97 (UniProtKB/Swiss-Prot),   A8MVD3 (UniProtKB/Swiss-Prot),   A8K8J0 (UniProtKB/Swiss-Prot),   Q9H8S3 (UniProtKB/Swiss-Prot),   Q8NEC7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001357110   ⟸   NM_001370181
- Peptide Label: isoform 1
- UniProtKB: Q8NEC7 (UniProtKB/Swiss-Prot),   H9KV97 (UniProtKB/Swiss-Prot),   A8MVD3 (UniProtKB/Swiss-Prot),   A8K8J0 (UniProtKB/Swiss-Prot),   Q9H8S3 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSP00000353695   ⟸   ENST00000360505
RefSeq Acc Id: ENSP00000422858   ⟸   ENST00000507281
RefSeq Acc Id: ENSP00000423779   ⟸   ENST00000509336
RefSeq Acc Id: ENSP00000423792   ⟸   ENST00000510865
RefSeq Acc Id: ENSP00000423639   ⟸   ENST00000512828
RefSeq Acc Id: ENSP00000378216   ⟸   ENST00000394728
RefSeq Acc Id: ENSP00000378218   ⟸   ENST00000394730
RefSeq Acc Id: ENSP00000422354   ⟸   ENST00000515279
RefSeq Acc Id: XP_047272135   ⟸   XM_047416179
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054206819   ⟸   XM_054350844
- Peptide Label: isoform X1
- UniProtKB: Q8NEC7 (UniProtKB/Swiss-Prot),   H9KV97 (UniProtKB/Swiss-Prot),   A8MVD3 (UniProtKB/Swiss-Prot),   A8K8J0 (UniProtKB/Swiss-Prot),   Q9H8S3 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_054206820   ⟸   XM_054350845
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054206817   ⟸   XM_054350842
- Peptide Label: isoform X1
- UniProtKB: Q8NEC7 (UniProtKB/Swiss-Prot),   H9KV97 (UniProtKB/Swiss-Prot),   A8MVD3 (UniProtKB/Swiss-Prot),   A8K8J0 (UniProtKB/Swiss-Prot),   Q9H8S3 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_054206818   ⟸   XM_054350843
- Peptide Label: isoform X1
- UniProtKB: Q8NEC7 (UniProtKB/Swiss-Prot),   H9KV97 (UniProtKB/Swiss-Prot),   A8MVD3 (UniProtKB/Swiss-Prot),   A8K8J0 (UniProtKB/Swiss-Prot),   Q9H8S3 (UniProtKB/Swiss-Prot)
Protein Domains
GST C-terminal   Methyltransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8NEC7-F1-model_v2 AlphaFold Q8NEC7 1-633 view protein structure

Promoters
RGD ID:6868254
Promoter ID:EPDNEW_H7264
Type:initiation region
Name:GSTCD_1
Description:glutathione S-transferase C-terminal domain containing
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H7266  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh384105,708,800 - 105,708,860EPDNEW
RGD ID:6868202
Promoter ID:EPDNEW_H7266
Type:initiation region
Name:GSTCD_2
Description:glutathione S-transferase C-terminal domain containing
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H7264  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh384105,710,813 - 105,710,873EPDNEW
RGD ID:6802351
Promoter ID:HG_KWN:48857
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   HeLa_S3
Transcripts:NM_024751,   UC003HXX.2,   UC010ILS.1
Position:
Human AssemblyChrPosition (strand)Source
Build 364106,849,179 - 106,849,679 (+)MPROMDB
RGD ID:6802353
Promoter ID:HG_KWN:48858
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:ENST00000394728,   UC003HXZ.2
Position:
Human AssemblyChrPosition (strand)Source
Build 364106,851,231 - 106,851,731 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:25806 AgrOrtholog
COSMIC GSTCD COSMIC
Ensembl Genes ENSG00000138780 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000360505 ENTREZGENE
  ENST00000360505.9 UniProtKB/Swiss-Prot
  ENST00000394728.4 UniProtKB/Swiss-Prot
  ENST00000394730 ENTREZGENE
  ENST00000394730.7 UniProtKB/Swiss-Prot
  ENST00000507281.5 UniProtKB/TrEMBL
  ENST00000509336.5 UniProtKB/TrEMBL
  ENST00000510865.5 UniProtKB/TrEMBL
  ENST00000512828.1 UniProtKB/TrEMBL
  ENST00000515279 ENTREZGENE
  ENST00000515279.6 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1050.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000138780 GTEx
HGNC ID HGNC:25806 ENTREZGENE
Human Proteome Map GSTCD Human Proteome Map
InterPro Glutathione-S-Trfase_C-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutathione-S-Trfase_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Methyltranfer_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:79807 UniProtKB/Swiss-Prot
NCBI Gene 79807 ENTREZGENE
OMIM 615912 OMIM
PANTHER GLUTATHIONE S-TRANSFERASE C-TERMINAL DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Methyltransf_32 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA144596427 PharmGKB
PROSITE GST_CTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47616 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF53335 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A8K8J0 ENTREZGENE
  A8MVD3 ENTREZGENE
  B7Z8J7 ENTREZGENE, UniProtKB/TrEMBL
  D6R949_HUMAN UniProtKB/TrEMBL
  D6R9W2_HUMAN UniProtKB/TrEMBL
  D6RCC4_HUMAN UniProtKB/TrEMBL
  D6RCC9_HUMAN UniProtKB/TrEMBL
  GSTCD_HUMAN UniProtKB/Swiss-Prot
  H9KV97 ENTREZGENE
  Q8NEC7 ENTREZGENE
  Q9H8S3 ENTREZGENE
UniProt Secondary A8K8J0 UniProtKB/Swiss-Prot
  A8MVD3 UniProtKB/Swiss-Prot
  H9KV97 UniProtKB/Swiss-Prot
  Q9H8S3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-19 GSTCD  glutathione S-transferase C-terminal domain containing    glutathione S-transferase, C-terminal domain containing  Symbol and/or name change 5135510 APPROVED