NCF1B (neutrophil cytosolic factor 1B (pseudogene)) - Rat Genome Database

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Gene: NCF1B (neutrophil cytosolic factor 1B (pseudogene)) Homo sapiens
Analyze
No known orthologs.
Symbol: NCF1B
Name: neutrophil cytosolic factor 1B (pseudogene) (Ensembl:neutrophil cytosolic factor 1B pseudogene)
RGD ID: 1602015
HGNC Page HGNC:32522
Description: Predicted to enable superoxide-generating NADPH oxidase activator activity. Predicted to be involved in respiratory burst and superoxide anion generation. Predicted to be part of NADPH oxidase complex. Predicted to be active in cytoplasm.
Type: pseudo (Ensembl: lncRNA)
RefSeq Status: PROVISIONAL
Previously known as: NCF-1B; neutrophil cytosolic factor 1B pseudogene; SH3PXD1B
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Related Functional Gene: NCF1  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38773,220,639 - 73,235,945 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl773,220,624 - 73,235,945 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p14 Ensembl773,220,646 - 73,235,787 (+)EnsemblGRCh38hg38GRCh38
GRCh37772,634,674 - 72,649,979 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36772,272,610 - 72,287,915 (+)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map7q11.23NCBI
CHM1_1772,780,661 - 72,795,967 (+)NCBICHM1_1
T2T-CHM13v2.0774,420,852 - 74,436,153 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2771,967,746 - 71,983,051 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9329953   PMID:9847074   PMID:10772875   PMID:12176908   PMID:12477932   PMID:12853948   PMID:19077231   PMID:21873635   PMID:26086043  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2148
Count of miRNA genes:766
Interacting mature miRNAs:926
Transcripts:ENST00000338578, ENST00000423083, ENST00000432102, ENST00000435988, ENST00000541521, ENST00000543901
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
G54020  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7q11.23UniSTS
RH45388  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7q11.23UniSTS
GeneMap99-GB4 RH Map19299.05UniSTS
WI-6056  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7q11.23UniSTS
GeneMap99-GB4 RH Map7422.74UniSTS
Whitehead-RH Map7398.4UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 79 721 13 1 1443 1 6 3 1 34 62 5
Low 1763 1038 979 368 429 234 1416 815 1023 194 600 1080 138 1053 741 1
Below cutoff 486 1194 694 233 47 205 2706 1267 2527 171 716 288 31 145 1961 2

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000423083
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl773,220,639 - 73,235,945 (+)Ensembl
RefSeq Acc Id: ENST00000432102
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl773,220,624 - 73,230,025 (+)Ensembl
RefSeq Acc Id: ENST00000435988
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl773,220,646 - 73,235,787 (+)Ensembl
RefSeq Acc Id: NR_003186
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38773,220,639 - 73,235,945 (+)NCBI
GRCh37772,634,674 - 72,649,979 (+)RGD
Build 36772,272,610 - 72,287,915 (+)NCBI Archive
CHM1_1772,780,661 - 72,795,967 (+)NCBI
T2T-CHM13v2.0774,420,852 - 74,436,153 (+)NCBI
CRA_TCAGchr7v2771,967,746 - 71,983,051 (+)ENTREZGENE
Sequence:
Protein Sequences
GenBank Protein A6NI72 (Get FASTA)   NCBI Sequence Viewer  
  BAG60825 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
Protein Domains
PX   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A6NI72-F1-model_v2 AlphaFold A6NI72 1-391 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:32522 AgrOrtholog
COSMIC NCF1B COSMIC
Ensembl Genes ENSG00000182487 Ensembl
  ENSG00000290838 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000423083 ENTREZGENE
Gene3D-CATH 3.30.1520.10 UniProtKB/Swiss-Prot
  SH3 Domains UniProtKB/Swiss-Prot
GTEx ENSG00000182487 GTEx
  ENSG00000290838 GTEx
HGNC ID HGNC:32522 ENTREZGENE
Human Proteome Map NCF1B Human Proteome Map
InterPro NADPH_oxidase_p47Phox_C UniProtKB/Swiss-Prot
  NCF1_SH3_1 UniProtKB/Swiss-Prot
  NCF1_SH3_2 UniProtKB/Swiss-Prot
  NECFESHC UniProtKB/Swiss-Prot
  P47PHOX UniProtKB/Swiss-Prot
  Phox UniProtKB/Swiss-Prot
  PX_dom_sf UniProtKB/Swiss-Prot
  PX_p47phox UniProtKB/Swiss-Prot
  SH3-like_dom_sf UniProtKB/Swiss-Prot
  SH3_domain UniProtKB/Swiss-Prot
NCBI Gene 654816 ENTREZGENE
PANTHER PTHR15706:SF6 UniProtKB/Swiss-Prot
  SH3 MULTIPLE DOMAIN UniProtKB/Swiss-Prot
Pfam NECFESHC UniProtKB/Swiss-Prot
  p47_phox_C UniProtKB/Swiss-Prot
  PF00787 UniProtKB/Swiss-Prot
  SH3_1 UniProtKB/Swiss-Prot
PharmGKB PA143485556 PharmGKB
PRINTS P47PHOX UniProtKB/Swiss-Prot
PROSITE PS50195 UniProtKB/Swiss-Prot
  SH3 UniProtKB/Swiss-Prot
SMART SH3 UniProtKB/Swiss-Prot
  SM00312 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50044 UniProtKB/Swiss-Prot
  SSF64268 UniProtKB/Swiss-Prot
UniProt A6NI72 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-08-28 NCF1B  neutrophil cytosolic factor 1B (pseudogene)  NCF1B  neutrophil cytosolic factor 1B pseudogene  Symbol and/or name change 19259463 PROVISIONAL