GSTT4 (glutathione S-transferase theta 4) - Rat Genome Database

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Gene: GSTT4 (glutathione S-transferase theta 4) Homo sapiens
Analyze
Symbol: GSTT4
Name: glutathione S-transferase theta 4
RGD ID: 1602006
HGNC Page HGNC:26930
Description: Predicted to enable glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: glutathione S-transferase theta pseudogene 1; glutathione S-transferase theta-4; GST class-theta-4; GSTTP1; HS322B1A; MGC119755; MGC119756
RGD Orthologs
Mouse
Rat
Dog
Pig
Alliance Orthologs
More Info more info ...
Related Pseudogenes: LOC100652871  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382223,989,115 - 24,005,453 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2223,998,401 - 24,005,453 (-)EnsemblGRCh38hg38GRCh38
GRCh372224,340,595 - 24,347,350 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362222,670,595 - 22,677,258 (-)NCBINCBI36Build 36hg18NCBI36
Celera228,141,156 - 8,147,155 (-)NCBICelera
Cytogenetic Map22q11.23NCBI
HuRef227,288,707 - 7,295,363 (-)NCBIHuRef
CHM1_12224,353,110 - 24,360,070 (-)NCBICHM1_1
T2T-CHM13v2.02224,405,779 - 24,412,527 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
schizophrenia  (IAGP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Schizophrenia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10334644   PMID:10591208   PMID:12477932   PMID:21873635  


Genomics

Comparative Map Data
GSTT4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382223,989,115 - 24,005,453 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2223,998,401 - 24,005,453 (-)EnsemblGRCh38hg38GRCh38
GRCh372224,340,595 - 24,347,350 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362222,670,595 - 22,677,258 (-)NCBINCBI36Build 36hg18NCBI36
Celera228,141,156 - 8,147,155 (-)NCBICelera
Cytogenetic Map22q11.23NCBI
HuRef227,288,707 - 7,295,363 (-)NCBIHuRef
CHM1_12224,353,110 - 24,360,070 (-)NCBICHM1_1
T2T-CHM13v2.02224,405,779 - 24,412,527 (-)NCBIT2T-CHM13v2.0
Gstt4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391075,650,777 - 75,658,405 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1075,650,777 - 75,658,377 (-)EnsemblGRCm39 Ensembl
GRCm381075,814,943 - 75,822,566 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1075,814,943 - 75,822,543 (-)EnsemblGRCm38mm10GRCm38
MGSCv371075,277,688 - 75,285,288 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361075,258,662 - 75,266,236 (-)NCBIMGSCv36mm8
Celera1076,859,618 - 76,867,219 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1038.58NCBI
Gstt4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82012,834,613 - 12,841,730 (+)NCBIGRCr8
mRatBN7.22012,835,178 - 12,842,306 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2012,835,178 - 12,842,292 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2013,541,554 - 13,548,873 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02012,902,481 - 12,909,800 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02013,374,423 - 13,381,746 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02013,778,185 - 13,784,813 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2013,778,178 - 13,784,827 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02015,968,093 - 15,975,083 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42013,238,379 - 13,239,777 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2014,326,728 - 14,333,740 (+)NCBICelera
Cytogenetic Map20p12NCBI
LOC486404
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12628,553,498 - 28,564,505 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2627,626,825 - 27,637,840 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02629,959,598 - 29,970,333 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2629,930,214 - 30,010,240 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12628,040,792 - 28,052,080 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02627,657,366 - 27,668,529 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02628,647,138 - 28,658,218 (-)NCBIUU_Cfam_GSD_1.0
GSTT4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1449,812,019 - 49,819,248 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11449,812,009 - 49,819,028 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21453,254,244 - 53,261,383 (-)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in GSTT4
4 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 22q11.21-11.23(chr22:21454661-24247140)x1 copy number loss See cases [RCV000137685] Chr22:21454661..24247140 [GRCh38]
Chr22:21808950..24643108 [GRCh37]
Chr22:20138950..22973108 [NCBI36]
Chr22:22q11.21-11.23		 pathogenic
GRCh38/hg38 22q11.22-11.23(chr22:22655333-24647020)x3 copy number gain See cases [RCV000143750] Chr22:22655333..24647020 [GRCh38]
Chr22:22997803..25042987 [GRCh37]
Chr22:21327803..23372987 [NCBI36]
Chr22:22q11.22-11.23		 uncertain significance
GRCh38/hg38 22q11.21-12.3(chr22:18178957-31821193)x3 copy number gain See cases [RCV000050768] Chr22:18178957..31821193 [GRCh38]
Chr22:18661724..32217179 [GRCh37]
Chr22:17041724..30547179 [NCBI36]
Chr22:22q11.21-12.3		 pathogenic
GRCh38/hg38 22q11.21-11.23(chr22:21443815-24235645)x1 copy number loss See cases [RCV000053074] Chr22:21443815..24235645 [GRCh38]
Chr22:21798104..24631613 [GRCh37]
Chr22:20128104..22961613 [NCBI36]
Chr22:22q11.21-11.23		 pathogenic
GRCh38/hg38 22q11.1-13.33(chr22:16916608-50739836)x3 copy number gain See cases [RCV000133646] Chr22:16916608..50739836 [GRCh38]
Chr22:17397498..51178264 [GRCh37]
Chr22:15777498..49525130 [NCBI36]
Chr22:22q11.1-13.33		 pathogenic
GRCh38/hg38 22q11.1-13.33(chr22:16916743-50739785)x3 copy number gain See cases [RCV000134730] Chr22:16916743..50739785 [GRCh38]
Chr22:17397633..51178213 [GRCh37]
Chr22:15777633..49525079 [NCBI36]
Chr22:22q11.1-13.33		 pathogenic
GRCh38/hg38 22q11.22-11.23(chr22:22669599-24670517)x3 copy number gain See cases [RCV000136060] Chr22:22669599..24670517 [GRCh38]
Chr22:23012069..25066484 [GRCh37]
Chr22:21342069..23396484 [NCBI36]
Chr22:22q11.22-11.23		 uncertain significance
GRCh38/hg38 22q11.23(chr22:23804407-24669609)x3 copy number gain See cases [RCV000137178] Chr22:23804407..24669609 [GRCh38]
Chr22:24146594..25065576 [GRCh37]
Chr22:22476594..23395576 [NCBI36]
Chr22:22q11.23		 uncertain significance
GRCh38/hg38 22q11.22-11.23(chr22:22660239-24644628)x3 copy number gain See cases [RCV000137410] Chr22:22660239..24644628 [GRCh38]
Chr22:23002709..25040595 [GRCh37]
Chr22:21332709..23370595 [NCBI36]
Chr22:22q11.22-11.23		 uncertain significance
GRCh38/hg38 22q11.22-11.23(chr22:22655333-24630890)x3 copy number gain See cases [RCV000142221] Chr22:22655333..24630890 [GRCh38]
Chr22:22997803..25026857 [GRCh37]
Chr22:21327803..23356857 [NCBI36]
Chr22:22q11.22-11.23		 uncertain significance
GRCh38/hg38 22q11.23(chr22:23377984-24563859)x3 copy number gain See cases [RCV000148169] Chr22:23377984..24563859 [GRCh38]
Chr22:23720171..24959827 [GRCh37]
Chr22:22050171..23289827 [NCBI36]
Chr22:22q11.23		 uncertain significance
GRCh38/hg38 22q11.22-11.23(chr22:22669543-24563859)x3 copy number gain See cases [RCV000050739] Chr22:22669543..24563859 [GRCh38]
Chr22:23012013..24959827 [GRCh37]
Chr22:21342013..23289827 [NCBI36]
Chr22:22q11.22-11.23		 conflicting interpretations of pathogenicity|uncertain significance|conflicting data from submitters
GRCh38/hg38 22q11.21-11.23(chr22:21454461-24247296)x1 copy number loss See cases [RCV000053077] Chr22:21454461..24247296 [GRCh38]
Chr22:21808750..24643264 [GRCh37]
Chr22:20138750..22973264 [NCBI36]
Chr22:22q11.21-11.23		 pathogenic
GRCh38/hg38 22q11.21-11.23(chr22:21457690-24220231)x1 copy number loss See cases [RCV000053087] Chr22:21457690..24220231 [GRCh38]
Chr22:21811979..24616199 [GRCh37]
Chr22:20141979..22946199 [NCBI36]
Chr22:22q11.21-11.23		 pathogenic
GRCh38/hg38 22q11.21-11.23(chr22:21562911-24307688)x1 copy number loss See cases [RCV000053090] Chr22:21562911..24307688 [GRCh38]
Chr22:21917200..24703656 [GRCh37]
Chr22:20247200..23033656 [NCBI36]
Chr22:22q11.21-11.23		 pathogenic
GRCh38/hg38 22q11.1-11.23(chr22:16916608-24358936)x3 copy number gain See cases [RCV000053104] Chr22:16916608..24358936 [GRCh38]
Chr22:17397498..24754904 [GRCh37]
Chr22:15777498..23084904 [NCBI36]
Chr22:22q11.1-11.23		 pathogenic
GRCh38/hg38 22q11.23(chr22:23338443-24577664)x3 copy number gain See cases [RCV000053175] Chr22:23338443..24577664 [GRCh38]
Chr22:23680630..24973632 [GRCh37]
Chr22:22010630..23303632 [NCBI36]
Chr22:22q11.23		 uncertain significance
GRCh38/hg38 22q11.23(chr22:23354221-24541945)x3 copy number gain See cases [RCV000053176] Chr22:23354221..24541945 [GRCh38]
Chr22:23696408..24937913 [GRCh37]
Chr22:22026408..23267913 [NCBI36]
Chr22:22q11.23		 uncertain significance
GRCh38/hg38 22q11.23(chr22:23414627-24563859)x3 copy number gain See cases [RCV000053182] Chr22:23414627..24563859 [GRCh38]
Chr22:23756814..24959827 [GRCh37]
Chr22:22086814..23289827 [NCBI36]
Chr22:22q11.23		 uncertain significance
GRCh37/hg19 22q11.23(chr22:24328565-24385948)x0 copy number loss See cases [RCV000136388] Chr22:24328565..24385948 [GRCh37]
Chr22:22658565..22715948 [NCBI36]
Chr22:22q11.23		 benign
GRCh38/hg38 22q11.21-11.23(chr22:20726972-24197852)x1 copy number loss See cases [RCV000136889] Chr22:20726972..24197852 [GRCh38]
Chr22:21081260..24593820 [GRCh37]
Chr22:19411260..22923820 [NCBI36]
Chr22:22q11.21-11.23		 pathogenic
GRCh38/hg38 22q11.23(chr22:23348201-24647020)x3 copy number gain See cases [RCV000143627] Chr22:23348201..24647020 [GRCh38]
Chr22:23690388..25042987 [GRCh37]
Chr22:22020388..23372987 [NCBI36]
Chr22:22q11.23		 uncertain significance
GRCh38/hg38 22q11.23(chr22:23311976-24644628)x3 copy number gain See cases [RCV000137701] Chr22:23311976..24644628 [GRCh38]
Chr22:23654163..25040595 [GRCh37]
Chr22:21984163..23370595 [NCBI36]
Chr22:22q11.23		 uncertain significance
GRCh38/hg38 22q11.23-12.3(chr22:23279231-36247369)x3 copy number gain See cases [RCV000138172] Chr22:23279231..36247369 [GRCh38]
Chr22:23621418..36643415 [GRCh37]
Chr22:21951418..34973361 [NCBI36]
Chr22:22q11.23-12.3		 pathogenic
GRCh38/hg38 22q11.23(chr22:23311976-24669609)x3 copy number gain See cases [RCV000139440] Chr22:23311976..24669609 [GRCh38]
Chr22:23654163..25065576 [GRCh37]
Chr22:21984163..23395576 [NCBI36]
Chr22:22q11.23		 likely benign|uncertain significance
GRCh38/hg38 22q11.22-11.23(chr22:22655333-24663664)x3 copy number gain See cases [RCV000141936] Chr22:22655333..24663664 [GRCh38]
Chr22:22997803..25059631 [GRCh37]
Chr22:21327803..23389631 [NCBI36]
Chr22:22q11.22-11.23		 uncertain significance
GRCh38/hg38 22q11.22-11.23(chr22:22686122-24577664)x3 copy number gain See cases [RCV000053161] Chr22:22686122..24577664 [GRCh38]
Chr22:23028586..24973632 [GRCh37]
Chr22:21358586..23303632 [NCBI36]
Chr22:22q11.22-11.23		 uncertain significance
GRCh38/hg38 22q11.23(chr22:23377984-24563859)x3 copy number gain See cases [RCV000053179] Chr22:23377984..24563859 [GRCh38]
Chr22:23720171..24959827 [GRCh37]
Chr22:22050171..23289827 [NCBI36]
Chr22:22q11.23		 conflicting interpretations of pathogenicity|uncertain significance|conflicting data from submitters
GRCh38/hg38 22q11.22-11.23(chr22:22660239-24596054)x3 copy number gain See cases [RCV000138249] Chr22:22660239..24596054 [GRCh38]
Chr22:23002709..24992021 [GRCh37]
Chr22:21332709..23322021 [NCBI36]
Chr22:22q11.22-11.23		 uncertain significance
GRCh38/hg38 22q11.22-11.23(chr22:22920775-24606692)x3 copy number gain See cases [RCV000143543] Chr22:22920775..24606692 [GRCh38]
Chr22:23262947..25002659 [GRCh37]
Chr22:21592947..23332659 [NCBI36]
Chr22:22q11.22-11.23		 uncertain significance
GRCh38/hg38 22q11.22-11.23(chr22:22669543-24563859)x3 copy number gain See cases [RCV000148079] Chr22:22669543..24563859 [GRCh38]
Chr22:23012013..24959827 [GRCh37]
Chr22:21342013..23289827 [NCBI36]
Chr22:22q11.22-11.23		 uncertain significance
GRCh38/hg38 22q11.23(chr22:23377784-24564000)x3 copy number gain See cases [RCV000053178] Chr22:23377784..24564000 [GRCh38]
Chr22:23719971..24959968 [GRCh37]
Chr22:22049971..23289968 [NCBI36]
Chr22:22q11.23		 uncertain significance
GRCh38/hg38 22q11.22-11.23(chr22:22660239-24600238)x3 copy number gain See cases [RCV000137795] Chr22:22660239..24600238 [GRCh38]
Chr22:23002709..24996205 [GRCh37]
Chr22:21332709..23326205 [NCBI36]
Chr22:22q11.22-11.23		 uncertain significance
GRCh38/hg38 22q11.21-12.3(chr22:20907226-37187347)x3 copy number gain See cases [RCV000137926] Chr22:20907226..37187347 [GRCh38]
Chr22:21261514..37583387 [GRCh37]
Chr22:19591514..35913333 [NCBI36]
Chr22:22q11.21-12.3		 pathogenic
GRCh38/hg38 22q11.21-11.23(chr22:21207181-24247140)x3 copy number gain See cases [RCV000138673] Chr22:21207181..24247140 [GRCh38]
Chr22:21561470..24643108 [GRCh37]
Chr22:19891470..22973108 [NCBI36]
Chr22:22q11.21-11.23		 uncertain significance
GRCh38/hg38 22q11.23(chr22:23310399-24643051)x3 copy number gain See cases [RCV000143562] Chr22:23310399..24643051 [GRCh38]
Chr22:23652586..25039018 [GRCh37]
Chr22:21982586..23369018 [NCBI36]
Chr22:22q11.23		 likely benign|uncertain significance
GRCh38/hg38 22q11.22-11.23(chr22:22703701-24669609)x3 copy number gain See cases [RCV000053163] Chr22:22703701..24669609 [GRCh38]
Chr22:23046186..25065576 [GRCh37]
Chr22:21376186..23395576 [NCBI36]
Chr22:22q11.22-11.23		 uncertain significance
GRCh38/hg38 22q11.23(chr22:23285152-24723136)x3 copy number gain See cases [RCV000053164] Chr22:23285152..24723136 [GRCh38]
Chr22:23627339..25119103 [GRCh37]
Chr22:21957339..23449103 [NCBI36]
Chr22:22q11.23		 uncertain significance
GRCh38/hg38 22q11.23(chr22:23338443-24610403)x3 copy number gain See cases [RCV000053174] Chr22:23338443..24610403 [GRCh38]
Chr22:23680630..25006370 [GRCh37]
Chr22:22010630..23336370 [NCBI36]
Chr22:22q11.23		 uncertain significance
GRCh38/hg38 22q11.23(chr22:23369950-24669609)x3 copy number gain See cases [RCV000053177] Chr22:23369950..24669609 [GRCh38]
Chr22:23712137..25065576 [GRCh37]
Chr22:22042137..23395576 [NCBI36]
Chr22:22q11.23		 uncertain significance
GRCh38/hg38 22q11.23(chr22:23311976-24600238)x3 copy number gain See cases [RCV000137995] Chr22:23311976..24600238 [GRCh38]
Chr22:23654163..24996205 [GRCh37]
Chr22:21984163..23326205 [NCBI36]
Chr22:22q11.23		 uncertain significance
GRCh38/hg38 22q11.23(chr22:23308686-24647020)x3 copy number gain See cases [RCV000141802] Chr22:23308686..24647020 [GRCh38]
Chr22:23650873..25042987 [GRCh37]
Chr22:21980873..23372987 [NCBI36]
Chr22:22q11.23		 uncertain significance
Single allele duplication Schizophrenia [RCV000754256] Chr22:22624794..24654160 [GRCh38]
Chr22:22q11.22-11.23		 likely pathogenic
Single allele duplication Schizophrenia [RCV000754258] Chr22:23317839..24597843 [GRCh38]
Chr22:22q11.23		 likely pathogenic
Single allele duplication Schizophrenia [RCV000754259] Chr22:23317839..24654160 [GRCh38]
Chr22:22q11.23		 likely pathogenic
NM_001358664.2(GSTT4):c.240A>G (p.Ala80=) single nucleotide variant not provided [RCV003433180] Chr22:24001286 [GRCh38]
Chr22:24343480 [GRCh37]
Chr22:22q11.23		 likely benign

QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406961441GWAS610417_Hprotein measurement QTL GWAS610417 (human)4e-30protein measurement222399845723998459Human
1581529BP71_HBlood pressure QTL 71 (human)20.001Blood pressurepulse pressure221109496637094966Human
407131298GWAS780274_Hphospholipid measurement, high density lipoprotein cholesterol measurement QTL GWAS780274 (human)2e-08phospholipid measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)222399433723994338Human
406925704GWAS574680_Hprotein measurement QTL GWAS574680 (human)3e-48protein measurement222399845723998459Human
406928555GWAS577531_Hprotein measurement QTL GWAS577531 (human)3e-24protein measurement222399845723998459Human
406960554GWAS609530_Hneutrophil count QTL GWAS609530 (human)5e-09neutrophil quantity (VT:0000222)blood neutrophil count (CMO:0000030)222399275523992756Human
406886542GWAS535518_Htriglyceride measurement QTL GWAS535518 (human)4e-11triglyceride measurementblood triglyceride level (CMO:0000118)222399378323993784Human
2289428BW313_HBody weight QTL 313 (human)2.090.0015Body weightBMI221134428437344284Human
406939607GWAS588583_Hprotein measurement QTL GWAS588583 (human)1e-510protein measurement222399275523992756Human
406925339GWAS574315_Hprotein measurement QTL GWAS574315 (human)5e-11protein measurement222399587723995878Human
406927643GWAS576619_Hprotein measurement QTL GWAS576619 (human)9e-14protein measurement222399587723995878Human
406939610GWAS588586_Hprotein measurement QTL GWAS588586 (human)6e-21protein measurement222399874623998747Human
406926844GWAS575820_Hprotein measurement QTL GWAS575820 (human)2e-10protein measurement222399587723995878Human
407411926GWAS1060902_Htriglyceride measurement QTL GWAS1060902 (human)1e-10triglyceride measurementblood triglyceride level (CMO:0000118)222400291824002919Human
406946014GWAS594990_Hserum gamma-glutamyl transferase measurement QTL GWAS594990 (human)4e-99serum gamma-glutamyl transferase measurementserum gamma-glutamyltransferase activity level (CMO:0002241)222399251723992518Human

Markers in Region
HS322B1A_9406  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372224,284,795 - 24,285,316UniSTSGRCh37
GRCh372224,340,402 - 24,340,926UniSTSGRCh37
Build 362222,614,795 - 22,615,316RGDNCBI36
Celera228,140,963 - 8,141,486RGD
HuRef227,288,514 - 7,289,037UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
437 929 1086 919 1881 778 971 1 183 400 121 944 2430 2228 20 1249 266 857 723 65

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001358664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_003081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024452199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024452200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024452201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024452202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054325477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054325478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054325479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054329452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054329453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054329454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054329455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC253536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL050257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP000351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC096726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC098108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC098364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC099710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000611600   ⟹   ENSP00000492640
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2223,998,401 - 24,005,361 (-)Ensembl
Ensembl Acc Id: ENST00000612717
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2223,998,490 - 24,005,453 (-)Ensembl
Ensembl Acc Id: ENST00000617532   ⟹   ENSP00000491048
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2224,000,150 - 24,005,361 (-)Ensembl
Ensembl Acc Id: ENST00000621179   ⟹   ENSP00000492273
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2223,998,401 - 24,005,453 (-)Ensembl
RefSeq Acc Id: NM_001358664   ⟹   NP_001345593
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382223,998,401 - 24,005,453 (-)NCBI
T2T-CHM13v2.02224,405,779 - 24,412,527 (-)NCBI
Sequence:
RefSeq Acc Id: NR_003081
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382223,998,401 - 24,005,453 (-)NCBI
GRCh372224,340,595 - 24,347,258 (-)RGD
Build 362222,670,595 - 22,677,258 (-)NCBI Archive
Celera228,141,156 - 8,147,155 (-)RGD
CHM1_12224,353,110 - 24,360,070 (-)NCBI
T2T-CHM13v2.02224,405,779 - 24,412,527 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024452199   ⟹   XP_024307967
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382223,998,401 - 24,005,453 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024452200   ⟹   XP_024307968
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382223,998,401 - 24,005,453 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024452202   ⟹   XP_024307970
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382223,989,115 - 24,005,453 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054325477   ⟹   XP_054181452
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02224,405,779 - 24,412,527 (-)NCBI
RefSeq Acc Id: XM_054325478   ⟹   XP_054181453
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02224,405,779 - 24,411,481 (-)NCBI
RefSeq Acc Id: XM_054325479   ⟹   XP_054181454
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02224,405,779 - 24,412,527 (-)NCBI
RefSeq Acc Id: XP_024307970   ⟸   XM_024452202
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_024307967   ⟸   XM_024452199
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_024307968   ⟸   XM_024452200
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: NP_001345593   ⟸   NM_001358664
- UniProtKB: A0A1W2PR19 (UniProtKB/Swiss-Prot),   A0A1W2PQM5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000492273   ⟸   ENST00000621179
Ensembl Acc Id: ENSP00000492640   ⟸   ENST00000611600
Ensembl Acc Id: ENSP00000491048   ⟸   ENST00000617532
RefSeq Acc Id: XP_054181452   ⟸   XM_054325477
- Peptide Label: isoform X7
RefSeq Acc Id: XP_054181454   ⟸   XM_054325479
- Peptide Label: isoform X8
RefSeq Acc Id: XP_054181453   ⟸   XM_054325478
- Peptide Label: isoform X8
Protein Domains
GST C-terminal   GST N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A1W2PR19-F1-model_v2 AlphaFold A0A1W2PR19 1-241 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:26930 AgrOrtholog
COSMIC GSTT4 COSMIC
Ensembl Genes ENSG00000276950 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000281748 UniProtKB/TrEMBL
Ensembl Transcript ENST00000611600 ENTREZGENE
  ENST00000611600.4 UniProtKB/TrEMBL
  ENST00000617532.4 UniProtKB/TrEMBL
  ENST00000621179 ENTREZGENE
  ENST00000621179.6 UniProtKB/Swiss-Prot
  ENST00000629684.2 UniProtKB/TrEMBL
  ENST00000630463.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1050.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutaredoxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000276950 GTEx
  ENSG00000281748 GTEx
HGNC ID HGNC:26930 ENTREZGENE
Human Proteome Map GSTT4 Human Proteome Map
InterPro Glutathione-S-Trfase_C-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutathione-S-Trfase_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutathione_S-Trfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutathione_S-Trfase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_C_Theta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_Theta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 25774 ENTREZGENE
PANTHER GLUTATHIONE S-TRANSFERASE THETA-1 UniProtKB/TrEMBL
  GLUTATHIONE S-TRANSFERASE THETA-4-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR43917 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GST_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_N UniProtKB/TrEMBL
  GST_N_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA166181539 PharmGKB
PROSITE GST_CTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_NTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47616 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52833 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1W2PP95_HUMAN UniProtKB/TrEMBL
  A0A1W2PQM5 ENTREZGENE, UniProtKB/TrEMBL
  A0A1W2PR19 ENTREZGENE
  A0A1W2PRF8_HUMAN UniProtKB/TrEMBL
  GSTT4_HUMAN UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-12-19 GSTT4  glutathione S-transferase theta 4  GSTTP1  glutathione S-transferase theta pseudogene 1  Symbol and/or name change 5135510 APPROVED