Nme4 (NME/NM23 nucleoside diphosphate kinase 4) - Rat Genome Database

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Gene: Nme4 (NME/NM23 nucleoside diphosphate kinase 4) Rattus norvegicus
Analyze
Symbol: Nme4 (Ensembl: Decr2)
Name: NME/NM23 nucleoside diphosphate kinase 4 (Ensembl:2,4-dienoyl-CoA reductase 2)
RGD ID: 1591334
Description: Enables GTPase binding activity. Predicted to be involved in lipid transport. Predicted to be located in mitochondrial intermembrane space. Predicted to be part of ribonucleoprotein complex. Orthologous to human NME4 (NME/NM23 nucleoside diphosphate kinase 4); PARTICIPATES IN cardiolipin metabolic pathway; de novo pyrimidine biosynthetic pathway; purine metabolic pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: expressed in non-metastatic cells 4; expressed in non-metastatic cells 4, protein; LOC685679; non-metastatic cells 4, protein expressed in; nucleoside diphosphate kinase 4; nucleoside diphosphate kinase, mitochondrial; similar to Nucleoside diphosphate kinase, mitochondrial precursor (NDP kinase, mitochondrial) (NDK) (nm23-M4) (Nucleoside diphosphate kinase D) (NDPKD)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,619,106 - 15,622,961 (-)NCBIGRCr8
mRatBN7.21015,114,624 - 15,118,479 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1015,002,926 - 15,118,479 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1019,853,968 - 19,857,864 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01019,342,855 - 19,346,743 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01014,842,683 - 14,846,551 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01015,461,567 - 15,465,422 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,431,638 - 15,465,413 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01015,275,267 - 15,279,122 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,360,310 - 15,364,165 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1014,783,047 - 14,786,902 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
afimoxifene  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
chloropicrin  (ISO)
chromium(6+)  (ISO)
clobetasol  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
indometacin  (EXP)
lipopolysaccharide  (ISO)
mercury dichloride  (EXP)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
thapsigargin  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
tungsten  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Localization and characterization of the mitochondrial isoform of the nucleoside diphosphate kinase in the pancreatic beta cell: evidence for its complexation with mitochondrial succinyl-CoA synthetase. Kowluru A, etal., Arch Biochem Biophys. 2002 Feb 15;398(2):160-9.
3. The human Nm23/nucleoside diphosphate kinases. Lacombe ML, etal., J Bioenerg Biomembr. 2000 Jun;32(3):247-58.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Metabolism and function of mitochondrial cardiolipin. Ren M, etal., Prog Lipid Res. 2014 Jul;55:1-16. doi: 10.1016/j.plipres.2014.04.001. Epub 2014 Apr 24.
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Dual function of mitochondrial Nm23-H4 protein in phosphotransfer and intermembrane lipid transfer: a cardiolipin-dependent switch. Schlattner U, etal., J Biol Chem. 2013 Jan 4;288(1):111-21. doi: 10.1074/jbc.M112.408633. Epub 2012 Nov 13.
Additional References at PubMed
PMID:10799505   PMID:14651853   PMID:14766980   PMID:18614015   PMID:18635542  


Genomics

Comparative Map Data
Nme4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,619,106 - 15,622,961 (-)NCBIGRCr8
mRatBN7.21015,114,624 - 15,118,479 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1015,002,926 - 15,118,479 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1019,853,968 - 19,857,864 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01019,342,855 - 19,346,743 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01014,842,683 - 14,846,551 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01015,461,567 - 15,465,422 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,431,638 - 15,465,413 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01015,275,267 - 15,279,122 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,360,310 - 15,364,165 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1014,783,047 - 14,786,902 (-)NCBICelera
Cytogenetic Map10q12NCBI
NME4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3816396,729 - 400,754 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl16396,725 - 410,367 (+)EnsemblGRCh38hg38GRCh38
GRCh3716446,729 - 450,754 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3616387,193 - 390,755 (+)NCBINCBI36Build 36hg18NCBI36
Build 3416387,192 - 390,754NCBI
Celera16647,739 - 651,301 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef16368,052 - 369,816 (+)NCBIHuRef
CHM1_116447,138 - 450,694 (+)NCBICHM1_1
T2T-CHM13v2.016392,618 - 396,999 (+)NCBIT2T-CHM13v2.0
Nme4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391726,310,708 - 26,314,650 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1726,310,708 - 26,314,576 (-)EnsemblGRCm39 Ensembl
GRCm381726,091,734 - 26,095,523 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1726,091,734 - 26,095,602 (-)EnsemblGRCm38mm10GRCm38
MGSCv371726,228,690 - 26,232,415 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361725,819,345 - 25,823,070 (-)NCBIMGSCv36mm8
Celera1726,625,701 - 26,629,418 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1713.06NCBI
Nme4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544216,808,215 - 16,811,302 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544216,808,215 - 16,811,302 (-)NCBIChiLan1.0ChiLan1.0
NME4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v218626,531 - 630,084 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,416,006 - 4,419,451 (+)NCBINHGRI_mPanPan1
PanPan1.116374,718 - 393,976 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16389,068 - 393,976 (+)Ensemblpanpan1.1panPan2
NME4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1640,119,443 - 40,122,418 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha641,382,427 - 41,385,445 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0640,461,109 - 40,464,127 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1640,149,487 - 40,152,505 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0640,109,690 - 40,112,657 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0640,588,923 - 40,591,941 (-)NCBIUU_Cfam_GSD_1.0
Nme4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344112,455,086 - 112,459,909 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936501553,931 - 557,744 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NME4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl341,306,175 - 41,310,312 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1341,306,167 - 41,321,002 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2341,117,780 - 41,121,920 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NME4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.15337,533 - 341,052 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl5337,562 - 341,205 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606830,831,389 - 30,835,230 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nme4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249131,234,191 - 1,237,602 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249131,234,292 - 1,237,602 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nme4
12 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:230
Count of miRNA genes:149
Interacting mature miRNAs:155
Transcripts:ENSRNOT00000027593
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10129497586Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402719233348Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402717245662Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10615418215990232Rat
1576304Schws7Schwannoma susceptibility QTL 70.0115nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)10476552719816042Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat

Markers in Region
RH128482  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21015,114,722 - 15,114,938 (+)MAPPERmRatBN7.2
Rnor_6.01015,461,666 - 15,461,881NCBIRnor6.0
Rnor_5.01015,275,366 - 15,275,581UniSTSRnor5.0
RGSC_v3.41015,360,409 - 15,360,624UniSTSRGSC3.4
Celera1014,783,146 - 14,783,361UniSTS
RH 3.4 Map10155.0UniSTS
Cytogenetic Map10q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
6 6 31 34 30 18 6 18 6 58 24 19 10 19 12

Sequence


RefSeq Acc Id: NM_001109478   ⟹   NP_001102948
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,619,106 - 15,622,961 (-)NCBI
mRatBN7.21015,114,624 - 15,118,479 (-)NCBI
Rnor_6.01015,461,567 - 15,465,422 (-)NCBI
Rnor_5.01015,275,267 - 15,279,122 (-)NCBI
RGSC_v3.41015,360,310 - 15,364,165 (-)RGD
Celera1014,783,047 - 14,786,902 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001102948 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM03992 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000027593.4
  ENSRNOP00000068775.1
  ENSRNOP00000095636.1
RefSeq Acc Id: NP_001102948   ⟸   NM_001109478
- UniProtKB: D3ZMT9 (UniProtKB/TrEMBL),   A6HD87 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
EF-hand   Nucleoside diphosphate kinase-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q66H66-F1-model_v2 AlphaFold Q66H66 1-446 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697070
Promoter ID:EPDNEW_R7594
Type:multiple initiation site
Name:Nme4_1
Description:NME/NM23 nucleoside diphosphate kinase 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R7593  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01015,465,425 - 15,465,485EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1591334 AgrOrtholog
BioCyc Gene G2FUF-25731 BioCyc
BioCyc Pathway PWY-7176 [UTP and CTP de novo biosynthesis] BioCyc
  PWY-7184 [pyrimidine deoxyribonucleotides de novo biosynthesis I] BioCyc
  PWY-7197 [pyrimidine deoxyribonucleotide phosphorylation] BioCyc
  PWY-7205 [CMP phosphorylation] BioCyc
  PWY-7210 [pyrimidine deoxyribonucleotides biosynthesis from CTP] BioCyc
  PWY-7221 [guanosine ribonucleotides de novo biosynthesis] BioCyc
  PWY-7224 [purine deoxyribonucleosides salvage] BioCyc
  PWY-7226 [guanosine deoxyribonucleotides de novo biosynthesis I] BioCyc
  PWY-7227 [adenosine deoxyribonucleotides de novo biosynthesis I] BioCyc
BioCyc Pathway Image PWY-7176 BioCyc
  PWY-7184 BioCyc
  PWY-7197 BioCyc
  PWY-7205 BioCyc
  PWY-7210 BioCyc
  PWY-7221 BioCyc
  PWY-7224 BioCyc
  PWY-7226 BioCyc
  PWY-7227 BioCyc
Ensembl Genes ENSRNOG00000032152 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000050424 Ensembl
Ensembl Transcript ENSRNOT00000027593.7 UniProtKB/TrEMBL
  ENSRNOT00000077826.2 UniProtKB/TrEMBL
  ENSRNOT00000100008.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.141 UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
  Translation factors UniProtKB/TrEMBL
InterPro DECR2-like UniProtKB/TrEMBL
  EF_hand_Ca-bd UniProtKB/TrEMBL
  L3_arc_euk UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  NDK-like_dom UniProtKB/TrEMBL
  NDK-like_dom_sf UniProtKB/TrEMBL
  Nucleoside_diP_kinase UniProtKB/TrEMBL
  Nucleoside_diP_kinase_AS UniProtKB/TrEMBL
  Ribosomal_L3 UniProtKB/TrEMBL
  Ribosomal_L3_CS UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
  Transl_elong_init/rib_B-barrel UniProtKB/TrEMBL
KEGG Report rno:685679 UniProtKB/TrEMBL
NCBI Gene 685679 ENTREZGENE
PANTHER 60S RIBOSOMAL PROTEIN L3 UniProtKB/TrEMBL
  NUCLEOSIDE DIPHOSPHATE KINASE UniProtKB/TrEMBL
  NUCLEOSIDE DIPHOSPHATE KINASE, MITOCHONDRIAL UniProtKB/TrEMBL
  PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING] UniProtKB/TrEMBL
  PTHR11363 UniProtKB/TrEMBL
  PTHR43296 UniProtKB/TrEMBL
Pfam adh_short_C2 UniProtKB/TrEMBL
  NDK UniProtKB/TrEMBL
  Ribosomal_L3 UniProtKB/TrEMBL
PhenoGen Nme4 PhenoGen
PRINTS GDHRDH UniProtKB/TrEMBL
  NUCDPKINASE UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/TrEMBL
PROSITE EF_HAND_2 UniProtKB/TrEMBL
  NDP_KINASES UniProtKB/TrEMBL
  RIBOSOMAL_L3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000032152 RatGTEx
  ENSRNOG00000050424 RatGTEx
SMART NDK UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
  SSF54919 UniProtKB/TrEMBL
  Translat_factor UniProtKB/TrEMBL
UniProt A0A8I6GLQ6_RAT UniProtKB/TrEMBL
  A6HD87 ENTREZGENE, UniProtKB/TrEMBL
  D3ZMT9 ENTREZGENE, UniProtKB/TrEMBL
  Q6TXF6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-05 Nme4  NME/NM23 nucleoside diphosphate kinase 4  Nme4  non-metastatic cells 4, protein expressed in  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-07-08 Nme4  non-metastatic cells 4, protein expressed in  LOC682382  similar to Nucleoside diphosphate kinase, mitochondrial precursor (NDP kinase, mitochondrial) (NDK) (nm23-M4) (Nucleoside diphosphate kinase D) (NDPKD)  Data merged from RGD:1584567 1643240 APPROVED
2008-05-15 Nme4  non-metastatic cells 4, protein expressed in  Nme4  expressed in non-metastatic cells 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Nme4  expressed in non-metastatic cells 4  LOC685679  similar to Nucleoside diphosphate kinase, mitochondrial precursor (NDP kinase, mitochondrial) (NDK) (nm23-M4) (Nucleoside diphosphate kinase D) (NDPKD)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC685679  similar to Nucleoside diphosphate kinase, mitochondrial precursor (NDP kinase, mitochondrial) (NDK) (nm23-M4) (Nucleoside diphosphate kinase D) (NDPKD)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC682382  similar to Nucleoside diphosphate kinase, mitochondrial precursor (NDP kinase, mitochondrial) (NDK) (nm23-M4) (Nucleoside diphosphate kinase D) (NDPKD)      Symbol and Name status set to provisional 70820 PROVISIONAL