Slc25a54 (solute carrier family 25, member 54) - Rat Genome Database

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Gene: Slc25a54 (solute carrier family 25, member 54) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Slc25a54
Name: solute carrier family 25, member 54
RGD ID: 1583925
Description: Predicted to enable ATP transmembrane transporter activity. Predicted to be involved in ADP transport and ATP transport. Predicted to be located in several cellular components, including chromatoid body; microtubule organizing center; and mitochondrial inner membrane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hypothetical protein LOC691448; LOC691448; similar to solute carrier family 25 member 24 isoform 1; uncharacterized protein LOC691448
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82199,399,650 - 199,458,476 (+)NCBIGRCr8
mRatBN7.22196,711,573 - 196,758,196 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2196,711,637 - 196,756,827 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2204,361,260 - 204,406,320 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02202,242,549 - 202,288,706 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02197,059,615 - 197,105,778 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02211,880,241 - 211,927,191 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2211,880,262 - 211,925,681 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02231,351,221 - 231,398,156 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42204,671,682 - 204,716,990 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2189,360,412 - 189,405,597 (+)NCBICelera
Cytogenetic Map2q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Slc25a54
568 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:18
Count of miRNA genes:17
Interacting mature miRNAs:18
Transcripts:ENSRNOT00000038315
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)218960362228801039Rat
61458Bp10Blood pressure QTL 103.42arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189020722215287351Rat
152025245Scl81Serum cholesterol level QTL 813.49blood cholesterol amount (VT:0000180)2122609194206936711Rat
70162Bp63Blood pressure QTL 635.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2157142209202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2193452645245889826Rat
61469Bp16Blood pressure QTL 165.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2157142078211086598Rat
4889834Pur24Proteinuria QTL 245.80.014urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)2184114274202447032Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2189599258226936289Rat
1359031Bp275Blood pressure QTL 275arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2185876309219753474Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2182171407227171407Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2182171407227171407Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150540301202447032Rat
1298083Bp158Blood pressure QTL 1582.62arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189020722215287351Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1331745Bp203Blood pressure QTL 2034.377arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2189599258218414891Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2189599258234599258Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2182171407227171407Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2179335906224335906Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2190613715226808892Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150341684202446871Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2168594495213594495Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2184165752229165752Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189599258234599258Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2150540301202447032Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2179946951224946951Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2182171407227171407Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2162765032207765032Rat
1598838Bp290Blood pressure QTL 2901.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166539266211539266Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2160564068205564068Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
2293084Iddm26Insulin dependent diabetes mellitus QTL 262.9blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2174930955213594495Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 25 61 60 42 24 42 3 76 28 18 45 18

Sequence


Ensembl Acc Id: ENSRNOT00000038315   ⟹   ENSRNOP00000032150
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2196,711,637 - 196,756,827 (+)Ensembl
Rnor_6.0 Ensembl2211,880,262 - 211,925,681 (+)Ensembl
RefSeq Acc Id: NM_001109640   ⟹   NP_001103110
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82199,399,706 - 199,444,891 (+)NCBI
mRatBN7.22196,711,637 - 196,756,827 (+)NCBI
Rnor_6.02211,880,262 - 211,925,681 (+)NCBI
Rnor_5.02231,351,221 - 231,398,156 (+)NCBI
RGSC_v3.42204,671,682 - 204,716,990 (+)RGD
Celera2189,360,412 - 189,405,597 (+)RGD
Sequence:
RefSeq Acc Id: XM_017591123   ⟹   XP_017446612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82199,399,650 - 199,458,476 (+)NCBI
mRatBN7.22196,711,574 - 196,758,196 (+)NCBI
Rnor_6.02211,880,241 - 211,927,191 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017591124   ⟹   XP_017446613
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82199,399,650 - 199,458,476 (+)NCBI
mRatBN7.22196,711,573 - 196,758,196 (+)NCBI
Rnor_6.02211,880,241 - 211,927,191 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039103170   ⟹   XP_038959098
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82199,399,824 - 199,458,476 (+)NCBI
mRatBN7.22196,711,751 - 196,758,196 (+)NCBI
RefSeq Acc Id: XM_039103171   ⟹   XP_038959099
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82199,399,823 - 199,458,476 (+)NCBI
mRatBN7.22196,711,772 - 196,758,196 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001103110 (Get FASTA)   NCBI Sequence Viewer  
  XP_017446612 (Get FASTA)   NCBI Sequence Viewer  
  XP_017446613 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959098 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959099 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL81975 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000032150.4
RefSeq Acc Id: NP_001103110   ⟸   NM_001109640
- UniProtKB: D3ZTW5 (UniProtKB/TrEMBL),   A6HV39 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017446612   ⟸   XM_017591123
- Peptide Label: isoform X1
- UniProtKB: D3ZTW5 (UniProtKB/TrEMBL),   A6HV39 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017446613   ⟸   XM_017591124
- Peptide Label: isoform X1
- UniProtKB: D3ZTW5 (UniProtKB/TrEMBL),   A6HV39 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000032150   ⟸   ENSRNOT00000038315
RefSeq Acc Id: XP_038959098   ⟸   XM_039103170
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038959099   ⟸   XM_039103171
- Peptide Label: isoform X3
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZTW5-F1-model_v2 AlphaFold D3ZTW5 1-473 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1583925 AgrOrtholog
BioCyc Gene G2FUF-51582 BioCyc
Ensembl Genes ENSRNOG00000027522 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000038315.5 UniProtKB/TrEMBL
Gene3D-CATH 1.50.40.10 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro EF-hand-like_dom UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_Ca-bd UniProtKB/TrEMBL
  Mit_carrier UniProtKB/TrEMBL
  Mitochondrial_sb/sol_carrier UniProtKB/TrEMBL
  Mt_carrier_dom UniProtKB/TrEMBL
KEGG Report rno:691448 UniProtKB/TrEMBL
NCBI Gene 691448 ENTREZGENE
PANTHER SOLUTE CARRIER FAMILY 25 UniProtKB/TrEMBL
  SOLUTE CARRIER FAMILY 25, MEMBER 54 UniProtKB/TrEMBL
Pfam EF-hand_7 UniProtKB/TrEMBL
  EF_hand_3 UniProtKB/TrEMBL
  Mito_carr UniProtKB/TrEMBL
PhenoGen Slc25a54 PhenoGen
PRINTS MITOCARRIER UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  SOLCAR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000027522 RatGTEx
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP Mitoch_carrier UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
UniProt A6HV39 ENTREZGENE, UniProtKB/TrEMBL
  D3ZTW5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-23 Slc25a54  solute carrier family 25, member 54  LOC691448  similar to solute carrier family 25 member 24 isoform 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC691448  similar to solute carrier family 25 member 24 isoform 1  LOC684863  similar to solute carrier family 25 member 24 isoform 1  Data merged from RGD:1585533 1643240 APPROVED
2006-11-19 LOC691448  similar to solute carrier family 25 member 24 isoform 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC684863  similar to solute carrier family 25 member 24 isoform 1      Symbol and Name status set to provisional 70820 PROVISIONAL