Ids (iduronate 2-sulfatase) - Rat Genome Database

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Gene: Ids (iduronate 2-sulfatase) Mus musculus
Analyze
Symbol: Ids
Name: iduronate 2-sulfatase
RGD ID: 1557423
MGI Page MGI
Description: Enables iduronate-2-sulfatase activity. Involved in dermatan sulfate proteoglycan catabolic process and heparan sulfate proteoglycan catabolic process. Located in lysosome. Is active in lysosomal lumen. Is expressed in nervous system and neural retina. Used to study mucopolysaccharidosis II. Human ortholog(s) of this gene implicated in mucopolysaccharidosis II. Orthologous to human IDS (iduronate 2-sulfatase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: alpha-L-iduronate sulfate sulfatase; AW214631; iduronate sulfatase; iduronate-2-sulfatase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X69,386,675 - 69,429,437 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX69,386,675 - 69,408,690 (-)EnsemblGRCm39 Ensembl
GRCm38X70,343,069 - 70,385,834 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX70,343,069 - 70,365,084 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X67,596,244 - 67,618,260 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X66,603,734 - 66,625,640 (-)NCBIMGSCv36mm8
CeleraX61,343,214 - 61,364,574 (-)NCBICelera
Cytogenetic MapXA7.2NCBI
cM MapX36.01NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
IdsMousemucopolysaccharidosis II  ISOIDS (Homo sapiens)1599819 RGD 
IdsMousemucopolysaccharidosis II  ISOIDS (Homo sapiens)12910721DNA:mutations:exon and intron:multipleRGD 
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
IdsMouseautistic disorder  ISOIDS (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
IdsMouseautosomal hemophilia A  ISOIDS (Homo sapiens)8554872ClinVar Annotator: match by term: AUTOSOMAL HEMOPHILIA AClinVarPMID:31690835
IdsMouseDevelopmental Disabilities  ISOIDS (Homo sapiens)8554872ClinVar Annotator: match by term: Global developmental delayClinVarPMID:25741868 more ...
IdsMouseEpidermolysis Bullosa Simplex 5D with Nail Dystrophy  ISOIDS (Homo sapiens)8554872ClinVar Annotator: match by term: Epidermolysis bullosa simplex with nail dystrophyClinVarPMID:28492532
IdsMousefactor VIII deficiency  ISOIDS (Homo sapiens)8554872ClinVar Annotator: match by term: Factor 8 deficiency and congenitalClinVarPMID:31690835
IdsMousegenetic disease  ISOIDS (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:10215411 more ...
IdsMousemucopolysaccharidosis II  ISOIDS (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10215411 more ...
IdsMousemucopolysaccharidosis II  ISOIDS (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10215411 more ...
IdsMousemucopolysaccharidosis III  ISOIDS (Homo sapiens)8554872ClinVar Annotator: match by term: Heparan sulfate sulfatase deficiencyClinVarPMID:25741868 and PMID:28492532
IdsMousemucopolysaccharidosis type IIIA  ISOIDS (Homo sapiens)8554872ClinVar Annotator: match by term: Mucopolysaccharidosis and MPS-III-AClinVarPMID:10447264 more ...
IdsMousesyndromic X-linked intellectual disability Lubs type  ISOIDS (Homo sapiens)8554872ClinVar Annotator: match by term: Syndromic X-linked intellectual disability Lubs typeClinVarPMID:22679399 more ...
1 to 11 of 11 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
IdsMouseLung Neoplasms  ISOIDS (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:27935865
IdsMousemucopolysaccharidosis II  ISOIDS (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
IdsMousemucopolysaccharidosis II  IAGP 13592920OMIM:309900MouseDO 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
IdsMousemucopolysaccharidosis II  ISOIDS (Homo sapiens)7240710 OMIM 

1 to 20 of 92 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
IdsMouse(-)-demecolcine increases expressionISOIDS (Homo sapiens)6480464Demecolcine results in increased expression of IDS mRNACTDPMID:23649840
IdsMouse1,2-dimethylhydrazine decreases expressionEXP 64804641 and 2-Dimethylhydrazine results in decreased expression of IDS mRNACTDPMID:22206623
IdsMouse17alpha-ethynylestradiol increases expressionISOIds (Rattus norvegicus)6480464Ethinyl Estradiol results in increased expression of IDS mRNACTDPMID:29097150
IdsMouse17beta-estradiol decreases expressionISOIDS (Homo sapiens)6480464Estradiol results in decreased expression of IDS mRNACTDPMID:16202921
IdsMouse2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of IDS mRNACTDPMID:21570461
IdsMouse2-methylcholine affects expressionISOIDS (Homo sapiens)6480464beta-methylcholine affects the expression of IDS mRNACTDPMID:21179406
IdsMouse3,4-methylenedioxymethamphetamine increases expressionEXP 6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of IDS mRNACTDPMID:20188158
IdsMouseaflatoxin B1 increases expressionISOIDS (Homo sapiens)6480464Aflatoxin B1 results in increased expression of IDS mRNACTDPMID:21641981 and PMID:27153756
IdsMouseall-trans-retinoic acid decreases expressionISOIDS (Homo sapiens)6480464Tretinoin results in decreased expression of IDS mRNACTDPMID:23724009
IdsMouseall-trans-retinoic acid increases expressionISOIDS (Homo sapiens)6480464Tretinoin results in increased expression of IDS mRNACTDPMID:23830798 and PMID:33167477
IdsMousearistolochic acid A increases expressionISOIDS (Homo sapiens)6480464aristolochic acid I results in increased expression of IDS mRNACTDPMID:33212167
IdsMousearsenous acid increases expressionISOIDS (Homo sapiens)6480464Arsenic Trioxide results in increased expression of IDS mRNACTDPMID:15761015
IdsMousebenzo[a]pyrene affects methylationISOIDS (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of IDS exon and Benzo(a)pyrene affects the methylation of IDS promoterCTDPMID:27901495
IdsMousebenzo[a]pyrene increases expressionISOIDS (Homo sapiens)6480464Benzo(a)pyrene results in increased expression of IDS mRNACTDPMID:32234424
IdsMousebeta-lapachone increases expressionISOIDS (Homo sapiens)6480464beta-lapachone results in increased expression of IDS mRNACTDPMID:38218311
IdsMousebis(2-ethylhexyl) phthalate decreases expressionEXP 6480464Diethylhexyl Phthalate results in decreased expression of IDS mRNACTDPMID:34319233
IdsMousebisphenol A affects expressionISOIds (Rattus norvegicus)6480464bisphenol A affects the expression of IDS mRNACTDPMID:25181051
IdsMousebisphenol A increases expressionISOIds (Rattus norvegicus)6480464bisphenol A results in increased expression of IDS mRNACTDPMID:29097150
IdsMousebisphenol F increases expressionEXP 6480464bisphenol F results in increased expression of IDS mRNACTDPMID:38685157
IdsMousecadmium atom increases expressionISOIDS (Homo sapiens)6480464Cadmium results in increased expression of IDS mRNACTDPMID:23369406

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Biological Process

  

Cellular Component

  
Object Symbol
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Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
IdsMousecytoplasm is_active_inIBAPANTHER:PTN000038764 more ...2290270 GO_CentralGO_REF:0000033
IdsMouselysosomal lumen is_active_inIDA 2290270 PMID:17876721MGIPMID:17876721
IdsMouselysosome is_active_inIMPMGI:36251222290270 PMID:16505002MGIPMID:16505002
IdsMouselysosome located_inIDA 2290270 PMID:15149955UniProtPMID:15149955
IdsMouselysosome located_inISOUniProtKB:P223042290270 GO_CentralGO_REF:0000119

Molecular Function
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1 to 20 of 95 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
IdsMouseabnormal appendicular skeleton morphology  IAGP 5509061 MGIPMID:17876721
IdsMouseabnormal basilar membrane morphology  IAGP 5509061 MGIPMID:22847837
IdsMouseabnormal body weight  IAGP 5509061 MGIPMID:20652491
IdsMouseabnormal bone structure  IAGP 5509061 MGIPMID:22704483
IdsMouseabnormal brain morphology  IAGP 5509061 MGIPMID:16505002
IdsMouseabnormal brainstem morphology  IAGP 5509061 MGIPMID:17876721
IdsMouseabnormal calcaneum morphology  IAGP 5509061 MGIPMID:17876721
IdsMouseabnormal clavicle morphology  IAGP 5509061 MGIPMID:17876721
IdsMouseabnormal coat/ hair morphology  IAGP 5509061 MGIPMID:22704483
IdsMouseabnormal cochlear ganglion morphology  IAGP 5509061 MGIPMID:22847837
IdsMouseabnormal cranium morphology  IAGP 5509061 MGIPMID:16505002
IdsMouseabnormal cranium morphology  IAGP 5509061 MGIPMID:17876721
IdsMouseabnormal digit morphology  IAGP 5509061 MGIPMID:16505002
IdsMouseabnormal digit morphology  IAGP 5509061 MGIPMID:17876721
IdsMouseabnormal digit morphology  IAGP 5509061 MGIPMID:12572850
IdsMouseabnormal facial morphology  IAGP 5509061 MGIPMID:20652491
IdsMouseabnormal foam cell morphology  IAGP 5509061 MGIPMID:20652491
IdsMouseabnormal gait  IAGP 5509061 MGIPMID:16505002
IdsMouseabnormal gait  IAGP 5509061 MGIPMID:22704483
IdsMouseabnormal glycosaminoglycan level  IAGP 5509061 MGIPMID:22847837
1 to 20 of 95 rows

1 to 9 of 9 rows
#
Reference Title
Reference Citation
1. Genetic and physical mapping of the biglycan gene on the mouse X chromosome. Chatterjee A, etal., Mamm Genome 1993;4(1):33-6.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Intermediate form of mucopolysaccharidosis type II (Hunter disease): a C1327 to T substitution in the iduronate sulfatase gene. Sukegawa K, etal., Biochem Biophys Res Commun. 1992 Mar 16;183(2):809-13.
9. Identification and characterization of 20 novel pathogenic variants in 60 unrelated Indian patients with mucopolysaccharidoses type I and type II. Uttarilli A, etal., Clin Genet. 2016 Dec;90(6):496-508. doi: 10.1111/cge.12795. Epub 2016 May 26.
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PMID:1572654   PMID:1937018   PMID:8325651   PMID:8352760   PMID:8439729   PMID:8678976   PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12572850  
PMID:15149955   PMID:15293786   PMID:15962010   PMID:16141072   PMID:16141073   PMID:16174644   PMID:16505002   PMID:17876721   PMID:19679226   PMID:20503373   PMID:20643830   PMID:20652491  
PMID:20876612   PMID:21873635   PMID:22096577   PMID:22279584   PMID:22704483   PMID:22847837   PMID:23568409   PMID:27228099   PMID:27590924   PMID:28207863   PMID:28334757   PMID:29606503  
PMID:29648648   PMID:30064964   PMID:32751752   PMID:34108486   PMID:34681597   PMID:35226042   PMID:35816218   PMID:37188686   PMID:37196079   PMID:37860991  



Ids
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X69,386,675 - 69,429,437 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX69,386,675 - 69,408,690 (-)EnsemblGRCm39 Ensembl
GRCm38X70,343,069 - 70,385,834 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX70,343,069 - 70,365,084 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X67,596,244 - 67,618,260 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X66,603,734 - 66,625,640 (-)NCBIMGSCv36mm8
CeleraX61,343,214 - 61,364,574 (-)NCBICelera
Cytogenetic MapXA7.2NCBI
cM MapX36.01NCBI
IDS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X149,476,988 - 149,505,306 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX149,476,988 - 149,521,096 (-)EnsemblGRCh38hg38GRCh38
GRCh37X148,558,519 - 148,586,836 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X148,368,206 - 148,394,698 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X148,274,422 - 148,292,552NCBI
CeleraX148,909,049 - 148,935,639 (-)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX137,513,419 - 137,540,564 (-)NCBIHuRef
CHM1_1X148,521,322 - 148,547,912 (-)NCBICHM1_1
T2T-CHM13v2.0X147,742,730 - 147,771,047 (-)NCBIT2T-CHM13v2.0
Ids
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X154,070,781 - 154,093,681 (-)NCBIGRCr8
mRatBN7.2X149,025,976 - 149,046,641 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX149,025,976 - 149,046,663 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX151,220,193 - 151,240,858 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X154,754,522 - 154,775,046 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X152,295,942 - 152,316,605 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0869,447,971 - 69,466,708 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl869,449,801 - 69,466,618 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0869,156,152 - 69,176,554 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X156,641,266 - 156,661,031 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1132,362,983 - 132,383,553 (+)NCBICelera
Cytogenetic MapXq37NCBI
Ids
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554981,860,628 - 1,886,867 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554981,863,002 - 1,886,720 (-)NCBIChiLan1.0ChiLan1.0
IDS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X148,782,502 - 148,809,520 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X148,786,110 - 148,813,018 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X138,493,117 - 138,520,017 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X148,919,692 - 148,946,441 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX148,912,475 - 148,946,441 (-)Ensemblpanpan1.1panPan2
IDS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X117,490,749 - 117,515,566 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX117,491,548 - 117,515,496 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX103,387,036 - 103,407,466 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X119,549,981 - 119,574,777 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX119,549,985 - 119,574,802 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X116,666,069 - 116,686,486 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X118,877,384 - 118,897,818 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X118,605,631 - 118,626,060 (-)NCBIUU_Cfam_GSD_1.0
Ids
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X115,525,779 - 115,551,763 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651362,993 - 88,774 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651362,966 - 88,844 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IDS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX121,572,807 - 121,596,513 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X121,572,797 - 121,596,525 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X139,050,899 - 139,063,575 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103232717
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X124,187,554 - 124,214,764 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX124,191,390 - 124,214,157 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236675231,986 - 13,481 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ids
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248832,030,783 - 2,055,519 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248832,031,208 - 2,056,379 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Ids
1061 total Variants

Predicted Target Of
Summary Value
Count of predictions:1765
Count of miRNA genes:756
Interacting mature miRNAs:972
Transcripts:ENSMUST00000101509, ENSMUST00000130519
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 16 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
4141630Gct6_mgranulosa cell tumorigenesis 6 (mouse)Not determined47179121129764756Mouse
13464140Hdlq108_mHDL QTL 108 (mouse)X5777196091771960Mouse
1301009Pbwg7_mpostnatal body weight growth 7 (mouse)Not determinedX3911371473113814Mouse
4141565Pbwg21_mpostnatal body weight growth 21 (mouse)Not determinedX3911371473113814Mouse
25314311Syncl3_msynaptonemal complex length 3 (mouse)X5198887789743606Mouse
13824980Ferq1_mgenetic fertility QTL 1 (mouse)X54045360148782996Mouse
4142200Rtwq1_mreduced testis weight QTL 1 (mouse)Not determined4147706075477203Mouse
1300794Spha2_msperm head anomaly 2 (mouse)Not determinedX3992149886260137Mouse
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse
1301278Bdln1_mbody length 1 (mouse)Not determinedX4170210675702218Mouse

1 to 10 of 16 rows
AW214631  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X70,343,416 - 70,343,506UniSTSGRCm38
MGSCv37X67,596,591 - 67,596,681UniSTSGRCm37
CeleraX61,343,561 - 61,343,651UniSTS
Cytogenetic MapXA7.1UniSTS
Whitehead/MRC_RHX729.73UniSTS
IDS  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X70,362,996 - 70,363,854UniSTSGRCm38
MGSCv37X67,616,171 - 67,617,029UniSTSGRCm37
CeleraX61,362,480 - 61,363,338UniSTS
Cytogenetic MapXA7.1UniSTS






1 to 30 of 33 rows
RefSeq Transcripts NM_001401926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006527846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017318393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017318394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030251229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030251230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC002315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF538870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ627044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL672026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BN000750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX294168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX510361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD740869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 33 rows

Ensembl Acc Id: ENSMUST00000101509   ⟹   ENSMUSP00000099046
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX69,386,675 - 69,408,690 (-)Ensembl
GRCm38.p6 EnsemblX70,343,069 - 70,365,084 (-)Ensembl
Ensembl Acc Id: ENSMUST00000130519   ⟹   ENSMUSP00000118732
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX69,394,676 - 69,404,697 (-)Ensembl
GRCm38.p6 EnsemblX70,351,070 - 70,361,091 (-)Ensembl
RefSeq Acc Id: NM_001401926   ⟹   NP_001388855
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X69,386,675 - 69,429,437 (-)NCBI
RefSeq Acc Id: NM_001401927   ⟹   NP_001388856
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X69,386,675 - 69,408,695 (-)NCBI
RefSeq Acc Id: NM_001401929   ⟹   NP_001388858
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X69,386,675 - 69,408,695 (-)NCBI
RefSeq Acc Id: NM_001401930   ⟹   NP_001388859
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X69,393,768 - 69,408,695 (-)NCBI
RefSeq Acc Id: NM_001401931   ⟹   NP_001388860
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X69,386,675 - 69,429,437 (-)NCBI
RefSeq Acc Id: NM_001401932   ⟹   NP_001388861
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X69,386,675 - 69,429,437 (-)NCBI
RefSeq Acc Id: NM_001401933   ⟹   NP_001388862
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X69,386,675 - 69,429,169 (-)NCBI
RefSeq Acc Id: NM_001401934   ⟹   NP_001388863
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X69,386,675 - 69,429,169 (-)NCBI
RefSeq Acc Id: NM_001401935   ⟹   NP_001388864
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X69,386,675 - 69,428,902 (-)NCBI
RefSeq Acc Id: NM_001401936   ⟹   NP_001388865
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X69,386,675 - 69,428,902 (-)NCBI
RefSeq Acc Id: NM_001401937   ⟹   NP_001388866
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X69,386,675 - 69,428,902 (-)NCBI
RefSeq Acc Id: NM_010498   ⟹   NP_034628
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X69,386,675 - 69,408,695 (-)NCBI
GRCm38X70,343,069 - 70,365,085 (-)NCBI
MGSCv37X67,596,244 - 67,618,260 (-)RGD
CeleraX61,343,214 - 61,364,574 (-)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006527846   ⟹   XP_006527909
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X69,386,753 - 69,408,720 (-)NCBI
GRCm38X70,343,147 - 70,365,116 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017318393   ⟹   XP_017173882
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X69,386,753 - 69,429,426 (-)NCBI
GRCm38X70,343,147 - 70,385,820 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017318394   ⟹   XP_017173883
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X69,386,753 - 69,429,426 (-)NCBI
GRCm38X70,343,147 - 70,385,820 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030251229   ⟹   XP_030107089
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X69,386,753 - 69,429,156 (-)NCBI
GRCm38X70,343,147 - 70,385,550 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030251230   ⟹   XP_030107090
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X69,386,753 - 69,429,376 (-)NCBI
GRCm38X70,343,147 - 70,385,770 (-)NCBI
Sequence:
1 to 27 of 27 rows
Protein RefSeqs NP_001388855 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388856 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388858 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388859 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388860 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388861 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388862 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388863 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388864 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388865 (Get FASTA)   NCBI Sequence Viewer  
  NP_001388866 (Get FASTA)   NCBI Sequence Viewer  
  NP_034628 (Get FASTA)   NCBI Sequence Viewer  
  XP_006527909 (Get FASTA)   NCBI Sequence Viewer  
  XP_017173882 (Get FASTA)   NCBI Sequence Viewer  
  XP_017173883 (Get FASTA)   NCBI Sequence Viewer  
  XP_030107089 (Get FASTA)   NCBI Sequence Viewer  
  XP_030107090 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA37880 (Get FASTA)   NCBI Sequence Viewer  
  AAN16453 (Get FASTA)   NCBI Sequence Viewer  
  BAE21082 (Get FASTA)   NCBI Sequence Viewer  
  BAE38612 (Get FASTA)   NCBI Sequence Viewer  
  CAF25312 (Get FASTA)   NCBI Sequence Viewer  
  CAI84996 (Get FASTA)   NCBI Sequence Viewer  
  EDL26597 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000099046
  ENSMUSP00000099046.3
GenBank Protein Q08890 (Get FASTA)   NCBI Sequence Viewer  
1 to 27 of 27 rows
1 to 5 of 19 rows
1 to 5 of 19 rows
RefSeq Acc Id: NP_034628   ⟸   NM_010498
- Peptide Label: isoform 1 precursor
- UniProtKB: Q32KI7 (UniProtKB/Swiss-Prot),   Q3TM30 (UniProtKB/Swiss-Prot),   Q08890 (UniProtKB/Swiss-Prot),   Q3V1R8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006527909   ⟸   XM_006527846
- Peptide Label: isoform X3
- UniProtKB: Q684Q4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017173883   ⟸   XM_017318394
- Peptide Label: isoform X2
- UniProtKB: Q684Q4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017173882   ⟸   XM_017318393
- Peptide Label: isoform X2
- UniProtKB: Q684Q4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030107090   ⟸   XM_030251230
- Peptide Label: isoform X2
- UniProtKB: Q684Q4 (UniProtKB/TrEMBL)
Sulfatase N-terminal

Name Modeler Protein Id AA Range Protein Structure
AF-Q08890-F1-model_v2 AlphaFold Q08890 1-552 view protein structure

RGD ID:6845847
Promoter ID:MM_KWN:60605
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000038111,   ENSMUST00000101509,   ENSMUST00000114633,   NM_010498_IDS,   UC009TJE.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X67,618,056 - 67,618,556 (-)MPROMDB
RGD ID:13680636
Promoter ID:EPDNEW_M24467
Type:initiation region
Name:Ids_1
Description:Mus musculus iduronate 2-sulfatase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X70,365,074 - 70,365,134EPDNEW


1 to 27 of 27 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000035847 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000101509 ENTREZGENE
  ENSMUST00000101509.9 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.720.10 UniProtKB/Swiss-Prot
InterPro Alkaline_phosphatase_core_sf UniProtKB/Swiss-Prot
  IDS UniProtKB/Swiss-Prot
  Sulfatase_CS UniProtKB/Swiss-Prot
  Sulfatase_N UniProtKB/Swiss-Prot
KEGG Report mmu:15931 UniProtKB/Swiss-Prot
MGD MGI:96417 ENTREZGENE
NCBI Gene 15931 ENTREZGENE
PANTHER IDURONATE 2-SULFATASE UniProtKB/Swiss-Prot
  IDURONATE 2-SULFATASE UniProtKB/Swiss-Prot
Pfam Sulfatase UniProtKB/Swiss-Prot
PhenoGen Ids PhenoGen
PROSITE SULFATASE_1 UniProtKB/Swiss-Prot
  SULFATASE_2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF53649 UniProtKB/Swiss-Prot
UniProt F6X9C5_MOUSE UniProtKB/TrEMBL
  IDS_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q32KI7 ENTREZGENE
  Q3TM30 ENTREZGENE
  Q3V1R8 ENTREZGENE, UniProtKB/TrEMBL
  Q684Q4 ENTREZGENE, UniProtKB/TrEMBL
  Q8CJ15_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q32KI7 UniProtKB/Swiss-Prot
  Q3TM30 UniProtKB/Swiss-Prot
1 to 27 of 27 rows