Advanced Search (OLGA)

Gene: Eif3i (eukaryotic translation initiation factor 3, subunit I) Mus musculus

Analyze

Symbol:

Eif3i

Name:

eukaryotic translation initiation factor 3, subunit I

RGD ID:

1557170

MGI Page

MGI

Description:

Contributes to translation initiation factor activity. Involved in translational initiation. Part of eukaryotic translation initiation factor 3 complex, eIF3m. Is active in synapse. Is expressed in several structures, including extracellular matrix; jaw; oral epithelium; and skeleton. Orthologous to human EIF3I (eukaryotic translation initiation factor 3 subunit I).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

36kD; 36kDa; D4Ertd632; D4Ertd632e; eIF-3-beta; Eif3; eIF3 p36; Eif3s2; eukaryotic translation initiation factor 3 subunit 2; eukaryotic translation initiation factor 3 subunit I; eukaryotic translation initiation factor 3, subunit 1; eukaryotic translation initiation factor 3, subunit 2 (beta); eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD); TGF-beta receptor binding protein; TGF-beta receptor-interacting protein 1; TRI; TRIP-1; Trip1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Related Pseudogenes:

4930503E24Rik Gm12189 Gm4371

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	129,485,767 - 129,494,441 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	129,485,753 - 129,494,441 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	129,591,974 - 129,600,648 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	129,591,960 - 129,600,648 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	129,269,218 - 129,277,892 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	129,094,278 - 129,102,917 (-)	NCBI		MGSCv36	mm8
Celera	4	127,925,718 - 127,934,385 (-)	NCBI		Celera
Cytogenetic Map	4	D2.2	NCBI
cM Map	4	63.26	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Colonic Neoplasms (ISO)

Neoplastic Cell Transformation (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (EXP,ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,6-dimethoxyphenol (ISO)

2-hydroxypropanoic acid (ISO)

3-chloropropane-1,2-diol (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (EXP)

all-trans-retinoic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenic trichloride (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

atrazine (ISO)

benzo[a]pyrene (EXP,ISO)

Benzo[k]fluoranthene (EXP)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

Bisphenol B (ISO)

cadmium atom (EXP,ISO)

cadmium dichloride (EXP,ISO)

carbon nanotube (EXP)

chlorophyllin (ISO)

chromium(6+) (EXP)

clobetasol (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP)

epoxiconazole (EXP)

fenthion (EXP)

flutamide (ISO)

folic acid (EXP)

folpet (EXP)

furfural (ISO)

glafenine (ISO)

ivermectin (ISO)

L-ascorbic acid (EXP)

lipopolysaccharide (ISO)

lovastatin (EXP)

Mesaconitine (ISO)

methidathion (EXP)

nefazodone (ISO)

nimesulide (ISO)

nitrates (EXP)

rac-lactic acid (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sodium chloride (ISO)

sunitinib (ISO)

T-2 toxin (ISO)

tamoxifen (EXP)

tanespimycin (ISO)

tetrachloromethane (EXP)

thapsigargin (ISO)

trimellitic anhydride (EXP)

triptonide (EXP)

tungsten (EXP)

valproic acid (ISO)

warfarin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cytoplasmic translational initiation (IBA)

formation of cytoplasmic translation initiation complex (IEA)

translational initiation (IDA,ISO)

Cellular Component

eukaryotic 43S preinitiation complex (IEA)

eukaryotic 48S preinitiation complex (IEA)

eukaryotic translation initiation factor 3 complex (IDA,ISO)

eukaryotic translation initiation factor 3 complex, eIF3m (IBA,IDA)

synapse (EXP,IDA)

Molecular Function

protein binding (IPI,ISO)

RNA binding (IBA)

translation initiation factor activity (IDA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

translation initiation pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	The scanning mechanism of eukaryotic translation initiation.	Hinnebusch AG Annu Rev Biochem. 2014;83:779-812. doi: 10.1146/annurev-biochem-060713-035802. Epub 2014 Jan 29.
2.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3.	Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.	Ko MS, etal., Development 2000 Apr;127(8):1737-49.
4.	MGDs mouse GO annotations	MGD data from the GO Consortium
5.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10349636	PMID:10922068	PMID:11042159	PMID:11076861	PMID:11830523	PMID:12477932	PMID:14971650	PMID:15489334	PMID:15747579	PMID:15782199	PMID:16141072	PMID:16141073
PMID:16541103	PMID:16602821	PMID:17473174	PMID:17532540	PMID:17581632	PMID:18799693	PMID:21267068	PMID:21327095	PMID:21677750	PMID:21873635	PMID:22260994	PMID:22460930
PMID:23665500	PMID:24003236	PMID:24457600	PMID:25211037	PMID:26365490	PMID:26496610	PMID:27883077	PMID:29484847	PMID:30196744	PMID:31162944	PMID:32236758	PMID:32325033
PMID:32434143	PMID:32554809	PMID:33601422	PMID:35012549	PMID:36114006	PMID:36417873	PMID:37689715

Genomics

Comparative Map Data

Eif3i
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	129,485,767 - 129,494,441 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	129,485,753 - 129,494,441 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	129,591,974 - 129,600,648 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	129,591,960 - 129,600,648 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	129,269,218 - 129,277,892 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	129,094,278 - 129,102,917 (-)	NCBI		MGSCv36	mm8
Celera	4	127,925,718 - 127,934,385 (-)	NCBI		Celera
Cytogenetic Map	4	D2.2	NCBI
cM Map	4	63.26	NCBI

EIF3I
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	32,222,407 - 32,236,170 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	32,221,077 - 32,245,397 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	32,688,008 - 32,701,771 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	32,460,558 - 32,469,792 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	32,357,118 - 32,366,296	NCBI
Celera	1	30,957,873 - 30,967,376 (+)	NCBI		Celera
Cytogenetic Map	1	p35.2	NCBI
HuRef	1	30,804,528 - 30,813,444 (+)	NCBI		HuRef
CHM1_1	1	32,803,548 - 32,812,800 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	32,080,311 - 32,094,075 (+)	NCBI		T2T-CHM13v2.0

Eif3i
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	147,219,457 - 147,226,910 (-)	NCBI		GRCr8
mRatBN7.2	5	141,935,135 - 141,942,589 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	141,935,044 - 141,942,676 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	144,636,149 - 144,643,601 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	146,405,975 - 146,413,427 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	146,403,047 - 146,410,505 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	147,796,580 - 147,803,853 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	147,796,662 - 147,803,851 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	151,525,848 - 151,532,876 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	5	140,409,828 - 140,417,281 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

Eif3i
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	10,588,929 - 10,595,869 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	10,588,929 - 10,595,869 (+)	NCBI	ChiLan1.0	ChiLan1.0

EIF3I
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	194,595,422 - 194,605,446 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	193,716,841 - 193,726,150 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	31,508,568 - 31,517,832 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	32,519,013 - 32,528,390 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	32,519,015 - 32,528,390 (+)	Ensembl	panpan1.1		panPan2

EIF3I
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	68,977,359 - 68,986,004 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	68,977,365 - 68,986,330 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	65,558,142 - 65,566,960 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	69,544,232 - 69,553,056 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	69,544,235 - 69,552,559 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	66,380,702 - 66,389,509 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	67,376,410 - 67,384,939 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	68,375,747 - 68,384,562 (-)	NCBI		UU_Cfam_GSD_1.0

Eif3i
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	49,447,117 - 49,454,030 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	15,271,289 - 15,279,580 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	15,271,977 - 15,278,810 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EIF3I
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	88,695,926 - 88,708,678 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	88,695,926 - 88,705,083 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	82,728,285 - 82,737,483 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EIF3I
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	100,638,868 - 100,648,822 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	100,639,280 - 100,648,756 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	16,037,677 - 16,047,663 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in Eif3i
537 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	640
Count of miRNA genes:	425
Interacting mature miRNAs:	480
Transcripts:	ENSMUST00000102593, ENSMUST00000135055, ENSMUST00000136843, ENSMUST00000143384, ENSMUST00000155428
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4142139	Adip12_m	adiposity 12 (mouse)			Not determined		4	124621281	156860686	Mouse
10047132	Albq19_m	albuminuria QTL 19 (mouse)			Not determined		4	112824389	146824389	Mouse
1301525	Lmb1_m	lupus in MRL and B6 F2 cross (mouse)			Not determined		4	124264957	150676858	Mouse
14746982	Manh56_m	mandible shape 56 (mouse)					4	117815917	151815917	Mouse
4141623	W6q13_m	weight 6 weeks QTL 13 (mouse)			Not determined			88982069	140468203	Mouse
12910797	Pwgrq4_m	pre-weaning growth rate QTL 4 (mouse)					4	105835310	141433838	Mouse
25314312	Syncl2_m	synaptonemal complex length 2 (mouse)					4	65718237	146584457	Mouse
12910794	Pwbwq8_m	post-weaning body weight QTL 8 (mouse)					4	105835310	141433838	Mouse
1300743	Skull6_m	skull morphology 6 (mouse)			Not determined		4	111009051	145009280	Mouse
1301382	Arvm2_m	autoimmune renal vasculitis 2 (mouse)			Not determined		4	107791564	141791756	Mouse
1302149	Tlsr2_m	thymic lymphoma suppressor region 2 (mouse)			Not determined		4	124264957	142230960	Mouse
12910813	Pwbwq4_m	pre-weaning body weight QTL 4 (mouse)					4	105835310	141433838	Mouse
4141093	W3q17_m	weight 3 weeks QTL 17 (mouse)			Not determined			88982069	140468203	Mouse
27226757	Femd1_m	femur midshaft diameter 1, 5 week (mouse)					4	123993793	144326570	Mouse
12910808	Pwbwq9_m	post-weaning body weight QTL 9 (mouse)					4	105835310	141433838	Mouse
1300621	Tpnr1_m	thermal pain response 1 (mouse)			Not determined		4	125230872	156860686	Mouse
11567249	Elorr3_m	ethanol induced loss of righting response 3 (mouse)					4	3722677	156268235	Mouse
4142493	Femwf13_m	femur work to failure 13 (mouse)			Not determined			116154678	150154782	Mouse
1301815	Sles2_m	systemic lupus erythmatosus suppressor 2 (mouse)			Not determined		4	94957579	150676858	Mouse
1300663	Start2_m	startle response 2 (mouse)			Not determined		4	107264957	141265153	Mouse
1300917	Gasa1_m	gastritis type A susceptibility locus 1 (mouse)			Not determined		4	124055093	142438020	Mouse
1301823	Bmd7_m	bone mineral density 7 (mouse)			Not determined		4	88982069	151654550	Mouse
10412210	Cypr6_m	cytokine production 6 (mouse)			Not determined		4	120617848	154617995	Mouse
1302078	Sluc21_m	susceptibility to lung cancer 21 (mouse)			Not determined		4	117401141	151401275	Mouse
10045620	Heal22_m	wound healing/regeneration 22 (mouse)			Not determined		4	125230872	156860686	Mouse
4142481	Gct1_m	granulosa cell tumorigenesis 1 (mouse)			Not determined		4	127784226	156860686	Mouse
1301793	Tlsr3_m	thymic lymphoma suppressor region 3 (mouse)			Not determined		4	129465811	136864536	Mouse
10412072	Ssen1_m	suseptibility to Sendai virus 1 (mouse)			Not determined		4	109658132	133154782	Mouse
4141065	Shali2_m	survival time to hyperoxic acute lung injury 2 (mouse)			Not determined			124055093	141572792	Mouse
13503348	Bntq18_m	bone traits QTL 18 (mouse)					4	120617848	154617995	Mouse
13208562	Wght7_m	weight 7 (mouse)					4	90888237	148084457	Mouse
1300781	Lith8_m	lithogenic gene 8 (mouse)			Not determined		4	107264957	141265153	Mouse
39128212	Lwq21_m	liver weight QTL 21 (mouse)					4	88982069	140468203	Mouse
4141180	Ssic1_m	susceptibility to small intestinal cancer 1 (mouse)			Not determined			120674005	154674151	Mouse
1301584	Lrdg2_m	light induced retinal degeneration 2 (mouse)			Not determined		4	129465811	151654550	Mouse
1301847	Fecq2_m	fecundity QTL 2 (mouse)			Not determined		4	100071971	134072206	Mouse
1302102	Bis1_m	beta-carboline-induced seizures 1 (mouse)			Not determined		4	119864433	153864536	Mouse
10043996	Gct5_m	granulosa cell tumorigenesis 5 (mouse)			Not determined		4	127784226	156860686	Mouse
26884445	Sklq7_m	skull length QTL 7, 10 week (mouse)					4	68018237	150884457	Mouse
10043985	Stheal12_m	soft tissue heal 12 (mouse)			Not determined		4	121342649	155342753	Mouse
1301982	Pltiq1_m	phospholipid transfer protein inducibility QTL 1 (mouse)			Not determined		4	124621281	156860686	Mouse
26884437	Sklq13_m	skull length QTL 13, 16 week (mouse)					4	57700000	155684457	Mouse
1300803	Sluc6_m	susceptibility to lung cancer 6 (mouse)			Not determined		4	120674005	154674151	Mouse
4141549	W10q10_m	weight 10 weeks QTL 10 (mouse)			Not determined			88982069	140468203	Mouse
4142061	Chlq16_m	circulating hormone level QTL 16 (mouse)			Not determined		4	121342649	155342753	Mouse
1357895	Ctrcts_m	cataract severity (mouse)			Not determined		4	45709925	138342753	Mouse
1300933	Cdcs9_m	cytokine deficiency colitis susceptibility 9 (mouse)			Not determined		4	125230872	156860686	Mouse
1300809	Ccrs2_m	corpus callosum hemisphere surface size 2 (mouse)			Not determined		4	107264957	141265153	Mouse
1301964	Bw8q2_m	body weight at 8 weeks QTL 2 (mouse)			Not determined		4	119864433	153864536	Mouse
1301452	Elsgp1_m	elevated serum gp70 1 (mouse)			Not determined		4	121342649	155342753	Mouse
1301106	Skts7_m	skin tumor susceptibility 7 (mouse)			Not determined		4	100071971	134072206	Mouse
10755520	Rbc1_m	red blood cell count 1 (mouse)					4	108477692	142477692	Mouse
10755521	Hct1_m	hematocrit 1 (mouse)					4	108477692	142477692	Mouse
10755522	Hgb1_m	hemoglobin 1 (mouse)					4	108477692	142477692	Mouse
27095924	Pglq2_m	pelvic girdle length QTL 2, 5 week (mouse)					4	69118237	130727311	Mouse
1300858	Tafat_m	tally ho associated mesenteric fat pad weight (mouse)			Not determined		4	124621281	156860686	Mouse
10755531	Lymph3_m	lymphocyte differential 3 (mouse)					4	124553483	156860686	Mouse
27095917	Scvln14_m	sacral vertebrae length 2, 16 week (mouse)					4	68018237	130277062	Mouse
15039382	Ltgq7_m	liver triglyceride QTL 7 (mouse)					4	105705794	139705794	Mouse
11533916	Mts1_m	mammary tumor susceptibility 1 (mouse)					4	125289325	156860686	Mouse
15039377	Bw45_m	body weight QTL 45 (mouse)					4	105705794	139705794	Mouse
1300839	Dyscalc2_m	dystrophic cardiac calcinosis 2 (mouse)			Not determined		4	111009051	145009280	Mouse
12880433	Fgf23lq1_m	FGF23 serum level QTL 1 (mouse)					4	101157197	135157197	Mouse
4141001	Tgq17_m	triglyceride QTL 17 (mouse)			Not determined			112523489	146523489	Mouse
15039378	Adip30_m	adiposity 30 (mouse)					4	105705794	139705794	Mouse
1357800	Tgq3_m	triglyceride QTL 3 (mouse)			Not determined		4	107055093	141055180	Mouse
15039385	Mvlq3_m	macrovesicular liver lesion QTL 3 (mouse)					4	112182386	146182386	Mouse

Markers in Region

D4Ertd632e

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	4	129,591,989 - 129,592,335	UniSTS	GRCm38
MGSCv37	4	129,269,233 - 129,269,579	UniSTS	GRCm37
Celera	4	127,925,733 - 127,926,079	UniSTS
Cytogenetic Map	4	D2.2	UniSTS
cM Map	4	61.0	UniSTS

RH140878

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	4	129,592,007 - 129,592,335	UniSTS	GRCm38
MGSCv37	4	129,269,251 - 129,269,579	UniSTS	GRCm37
Celera	4	127,925,751 - 127,926,079	UniSTS
Cytogenetic Map	4	D2.2	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_018799	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF188297	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF271072	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK002896	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK010781	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK012375	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK089340	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK149955	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK172208	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK199438	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL671759	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC029625	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BP769420	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466552	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CJ079467	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU210937	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000102593 ⟹ ENSMUSP00000099653

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	4	129,485,753 - 129,494,441 (-)	Ensembl
GRCm38.p6 Ensembl	4	129,591,960 - 129,600,648 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000135055 ⟹ ENSMUSP00000120776

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	4	129,487,319 - 129,494,392 (-)	Ensembl
GRCm38.p6 Ensembl	4	129,593,526 - 129,600,599 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000136843

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	4	129,487,122 - 129,489,561 (-)	Ensembl
GRCm38.p6 Ensembl	4	129,593,329 - 129,595,768 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000143384

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	4	129,491,995 - 129,494,409 (-)	Ensembl
GRCm38.p6 Ensembl	4	129,598,202 - 129,600,616 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000155428

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	4	129,488,920 - 129,494,392 (-)	Ensembl
GRCm38.p6 Ensembl	4	129,595,127 - 129,600,599 (-)	Ensembl

RefSeq Acc Id:

NM_018799 ⟹ NP_061269

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	4	129,485,767 - 129,494,441 (-)	NCBI
GRCm38	4	129,591,974 - 129,600,648 (-)	ENTREZGENE
MGSCv37	4	129,269,218 - 129,277,892 (-)	RGD
Celera	4	127,925,718 - 127,934,385 (-)	RGD
cM Map	4		ENTREZGENE

Sequence:

show sequence

AGTCTTTTTCCGGTCCCACTCACATTGCCTCTCTCCTCGCGTCACCGCCAGGATGAAACCCATC
CTGCTGCAGGGCCATGAGCGGTCCATCACGCAGATCAAGTATAACCGCGAAGGAGACCTTCTCT
TCACCGTGGCCAAAGACCCTATCGTCAACGTGTGGTACTCTGTCAATGGGGAGAGGCTAGGCAC
CTACATGGGCCACACTGGAGCTGTGTGGTGCGTGGATGCTGACTGGGACACCAAGCATGTCCTT
ACTGGCTCAGCTGACAACAGCTGTCGTCTCTGGGACTGTGAAACAGGGAAGCAGCTGGCCCTAC
TCAAGACCAACTCAGCTGTCCGGACCTGCGGCTTTGACTTTGGGGGCAACATCATCATGTTCTC
CACAGACAAGCAGATGGGGTATCAGTGCTTCGTGAGCTTCTTTGATCTGCGGGATCCAAGCCAG
ATCGACAGCAACGAGCCCTACATGAAGATCCCCTGTAATGATTCCAAGATCACCAGTGCCGTCT
GGGGCCCCCTCGGGGAGTGCGTCATCGCAGGCCACGAGAGCGGAGAGCTCAACCAGTATAGCGC
CAAGTCTGGAGAGGTGTTGGTGAACGTAAAGGAACACTCTCGGCAGATCAATGACATCCAGTTG
TCTAGAGACATGACCATGTTTGTCACTGCATCTAAGGACAACACAGCTAAGCTCTTCGACTCCA
CGACTCTTGAACATCAGAAGACTTTCCGAACAGAGCGTCCTGTCAACTCGGCTGCTCTCTCTCC
CAACTATGACCATGTGGTGCTGGGAGGAGGTCAGGAAGCCATGGATGTGACCACAACCTCCACC
AGGATTGGCAAGTTTGAGGCCAGGTTCTTCCATTTGGCTTTTGAGGAAGAGTTTGGAAGAGTCA
AGGGCCACTTTGGACCGATCAACAGCGTTGCCTTCCATCCTGATGGCAAGAGCTACAGCAGCGG
TGGCGAAGATGGTTACGTCCGCATCCACTACTTCGACCCACAGTACTTTGAGTTCGAGTTTGAG
GCCTAAGTTCTGGGTCTCCATCCACAACAGAGAAGCTGCTCACAGAAGGTTTTAGACTGAGAAA
TAAATTAGTTTGTTAAAAATAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_061269	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF01455	(Get FASTA)	NCBI Sequence Viewer
	AAF76199	(Get FASTA)	NCBI Sequence Viewer
	AAH29625	(Get FASTA)	NCBI Sequence Viewer
	BAB22440	(Get FASTA)	NCBI Sequence Viewer
	BAB27177	(Get FASTA)	NCBI Sequence Viewer
	BAB28197	(Get FASTA)	NCBI Sequence Viewer
	BAC40847	(Get FASTA)	NCBI Sequence Viewer
	BAE42882	(Get FASTA)	NCBI Sequence Viewer
	EDL30181	(Get FASTA)	NCBI Sequence Viewer
	EDL30182	(Get FASTA)	NCBI Sequence Viewer
	EDL30183	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000099653
	ENSMUSP00000099653.5
	ENSMUSP00000120776.2
GenBank Protein	Q9QZD9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_061269 ⟸ NM_018799

- UniProtKB:

Q9QZD9 (UniProtKB/Swiss-Prot), Q3T9Y8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDT
KHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLR
DPSQIDSNEPYMKIPCNDSKITSAVWGPLGECVIAGHESGELNQYSAKSGEVLVNVKEHSRQIN
DIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVT
TTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFE
FEFEA

hide sequence

Ensembl Acc Id:

ENSMUSP00000120776 ⟸ ENSMUST00000135055

Ensembl Acc Id:

ENSMUSP00000099653 ⟸ ENSMUST00000102593

Protein Domains

Anaphase-promoting complex subunit 4-like WD40

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9QZD9-F1-model_v2	AlphaFold	Q9QZD9	1-325	view protein structure

Promoters

RGD ID:

6835191

Promoter ID:

MM_KWN:39803

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Liver

Transcripts:

OTTMUST00000021782

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	4	129,272,276 - 129,272,776 (-)	MPROMDB

RGD ID:

6834683

Promoter ID:

MM_KWN:39804

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

OTTMUST00000021724, OTTMUST00000021725, OTTMUST00000021726, OTTMUST00000021727, OTTMUST00000021728, OTTMUST00000021729, OTTMUST00000021730, OTTMUST00000021731, OTTMUST00000021732, OTTMUST00000021733, OTTMUST00000021778, OTTMUST00000021779, OTTMUST00000021780, OTTMUST00000021781, UC008UXR.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	4	129,277,639 - 129,278,139 (+)	MPROMDB

RGD ID:

6884778

Promoter ID:

EPDNEW_M5840

Type:

initiation region

Name:

Eif3i_1

Description:

Mus musculus eukaryotic translation initiation factor 3, subunitI , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	4	129,600,620 - 129,600,680	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1860763	AgrOrtholog
Ensembl Genes	ENSMUSG00000028798	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000102593	ENTREZGENE
	ENSMUST00000102593.11	UniProtKB/Swiss-Prot
	ENSMUST00000135055.8	UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Apc4-like_WD40_dom	UniProtKB/TrEMBL
	eIF3i	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40_repeat_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:54709	UniProtKB/Swiss-Prot
MGD	MGI:1860763	ENTREZGENE
NCBI Gene	54709	ENTREZGENE
PANTHER	EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I	UniProtKB/Swiss-Prot
	EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I	UniProtKB/Swiss-Prot
	EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I	UniProtKB/TrEMBL
	EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I	UniProtKB/TrEMBL
Pfam	ANAPC4_WD40	UniProtKB/TrEMBL
	WD40	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Eif3i	PhenoGen
PROSITE	WD_REPEATS_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD_REPEATS_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD_REPEATS_REGION	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	WD40	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF50978	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A2AE03_MOUSE	UniProtKB/TrEMBL
	EIF3I_MOUSE	UniProtKB/Swiss-Prot
	Q3T9Y8	ENTREZGENE, UniProtKB/TrEMBL
	Q8BTM6_MOUSE	UniProtKB/TrEMBL
	Q9QZD9	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

RGD Manual Annotations

Send us a Message

Imported Disease Annotations - CTD

RGD Manual Annotations