Or4f53 (olfactory receptor family 4 subfamily F member 53) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Or4f53 (olfactory receptor family 4 subfamily F member 53) Mus musculus
Analyze
No known orthologs.
Symbol: Or4f53
Name: olfactory receptor family 4 subfamily F member 53
RGD ID: 1552914
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GA_x6K02T2Q125-72308574-72309512; MOR245-; MOR245-10; olfactory receptor 1276; olfactory receptor MOR245-10; Olfr1276
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392111,087,462 - 111,088,400 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2111,084,861 - 111,092,371 (+)EnsemblGRCm39 Ensembl
GRCm382111,257,117 - 111,258,055 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2111,254,516 - 111,262,026 (+)EnsemblGRCm38mm10GRCm38
MGSCv372111,097,274 - 111,098,212 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362111,057,956 - 111,058,894 (+)NCBIMGSCv36mm8
Celera2112,413,280 - 112,414,218 (+)NCBICelera
Cytogenetic Map2E3NCBI
cM Map256.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (ISA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11802173   PMID:11875048   PMID:14611657   PMID:19474196   PMID:21873635   PMID:32295537  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:60
Count of miRNA genes:59
Interacting mature miRNAs:60
Transcripts:ENSMUST00000073322
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
1301909Smdq2_msegregation of mitochondrial DNA QTL 2 (mouse)Not determined292778465126778607Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
11532731Sluc31a_msusceptibility to lung cancer 31a (mouse)288015003122015170Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260520612119355518Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
12904935Edlmmq2_mextensor digitorum longus muscle mass QTL 2 (mouse)297210364131210364Mouse
1302071Fembrs1_mfemur breaking strength 1 (mouse)Not determined2100942930134943090Mouse
10045885Cplaq15_mcircadian period of locomotor activity 15 (mouse)Not determined2110916118154354667Mouse
1302203Gvhd3_mgraft-versus host disease 3 (mouse)Not determined2100942930134943090Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
4142223Femwf4_mfemur work to failure 4 (mouse)Not determined88143423122143570Mouse
15092054Egrme5_mearly growth rate, maternal effect 5 (mouse)282190187118004745Mouse
4141448Mpaps1_mmicrophthalmia anophthalmia susceptibility 1 (mouse)Not determined97028557112115196Mouse
4142088Parms1_mpatched associated RMS 1 (mouse)Not determined74524117114123532Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
12904954Gmmq2_mgastrocnemius muscle mass QTL 2 (mouse)297210364131210364Mouse
1301330Tbbmd2_mtotal body bone mineral density 2 (mouse)Not determined2100942930134943090Mouse
11038697Ltpr2d_mLeishmania tropica response 2d (mouse)286095716120095823Mouse
11038698Ltpr2c_mLeishmania tropica response 2c (mouse)286095716120095823Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
11049568Lmr28c_mleishmaniasis resistance 28c (mouse)297123370131123532Mouse
11049569Lmr28d_mleishmaniasis resistance 28d (mouse)297123370131123532Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
1301087Bbaa15_mB.burgdorferi-associated arthritis 15 (mouse)Not determined2110489658144489807Mouse
1301825Pbrgcsf1_mperipheral blood stem cell response to granulocyte colony stimulating factor 1 (mouse)Not determined2106233580140233729Mouse
4141802Ignpq1_mIgA nephropathy QTL 1 (mouse)Not determined2100824060134824269Mouse
1301834Bits1_mbitterness sensitivity 1 (mouse)Not determined287440643121440778Mouse
11041906Lmr28a_mleishmaniasis resistance 28a (mouse)2103095716129213005Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
1558901Skmw8_mskeletal muscle weight 8 (mouse)Not determined284008488118008593Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1301109Dntcs2_mdental caries susceptibility 2 (mouse)Not determined240885493114910165Mouse
1300852Lmr14_mleishmaniasis resistance 14 (mouse)Not determined286095716120095823Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
10043894Bw22_mbody weight QTL 22 (mouse)Not determined280895334114895334Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
11049565Lmr28g_mleishmaniasis resistance 28g (mouse)286095716120095823Mouse
1301098Cd8mts3_mCD8 memory T cell subset 3 (mouse)Not determined291089974125090104Mouse
10043875Bw25_mbody weight QTL 25 (mouse)Not determined2107255676141255676Mouse

Markers in Region
UniSTS:485086  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382111,257,117 - 111,258,055UniSTSGRCm38
MGSCv372111,097,274 - 111,098,212UniSTSGRCm37
Celera2112,413,280 - 112,414,218UniSTS
Cytogenetic Map2E3UniSTS
UniSTS:495594  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382111,257,038 - 111,258,086UniSTSGRCm38
MGSCv372111,097,195 - 111,098,243UniSTSGRCm37
Celera2112,413,201 - 112,414,249UniSTS
Cytogenetic Map2E3UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000073322   ⟹   ENSMUSP00000073046
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2111,087,462 - 111,088,400 (+)Ensembl
GRCm38.p6 Ensembl2111,257,117 - 111,258,055 (+)Ensembl
Ensembl Acc Id: ENSMUST00000213658
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2111,084,861 - 111,092,371 (+)Ensembl
GRCm38.p6 Ensembl2111,254,516 - 111,262,026 (+)Ensembl
Ensembl Acc Id: ENSMUST00000218065   ⟹   ENSMUSP00000151987
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2111,084,861 - 111,092,371 (+)Ensembl
GRCm38.p6 Ensembl2111,254,516 - 111,262,026 (+)Ensembl
RefSeq Acc Id: NM_146395   ⟹   NP_666507
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392111,087,462 - 111,088,400 (+)NCBI
GRCm382111,257,117 - 111,258,055 (+)ENTREZGENE
MGSCv372111,097,274 - 111,098,212 (+)RGD
Celera2112,413,280 - 112,414,218 (+)RGD
cM Map2 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_666507 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAL61363 (Get FASTA)   NCBI Sequence Viewer  
  AAP71670 (Get FASTA)   NCBI Sequence Viewer  
  EDL27803 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000073046
  ENSMUSP00000073046.2
  ENSMUSP00000151987.2
RefSeq Acc Id: NP_666507   ⟸   NM_146395
- UniProtKB: Q8VF40 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000151987   ⟸   ENSMUST00000218065
Ensembl Acc Id: ENSMUSP00000073046   ⟸   ENSMUST00000073322
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VF40-F1-model_v2 AlphaFold Q8VF40 1-312 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3031110 AgrOrtholog
Ensembl Genes ENSMUSG00000063844 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000073322 ENTREZGENE
  ENSMUST00000073322.2 UniProtKB/TrEMBL
  ENSMUST00000218065.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfactory_Receptors UniProtKB/TrEMBL
KEGG Report mmu:258390 UniProtKB/TrEMBL
MGD MGI:3031110 ENTREZGENE
NCBI Gene 258390 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or4f53 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt Q8VF40 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or4f53  olfactory receptor family 4 subfamily F member 53  Olfr1276  olfactory receptor 1276  Symbol and/or name change 5135510 APPROVED