Or4f53 (olfactory receptor family 4 subfamily F member 53) - Rat Genome Database

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Gene: Or4f53 (olfactory receptor family 4 subfamily F member 53) Mus musculus
Analyze
No known orthologs.
Symbol: Or4f53
Name: olfactory receptor family 4 subfamily F member 53
RGD ID: 1552914
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GA_x6K02T2Q125-72308574-72309512; MOR245-; MOR245-10; olfactory receptor 1276; olfactory receptor MOR245-10; Olfr1276
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392111,087,462 - 111,088,400 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2111,084,861 - 111,092,371 (+)EnsemblGRCm39 Ensembl
GRCm382111,257,117 - 111,258,055 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2111,254,516 - 111,262,026 (+)EnsemblGRCm38mm10GRCm38
MGSCv372111,097,274 - 111,098,212 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362111,057,956 - 111,058,894 (+)NCBIMGSCv36mm8
Celera2112,413,280 - 112,414,218 (+)NCBICelera
Cytogenetic Map2E3NCBI
cM Map256.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or4f53Mouse4,4'-sulfonyldiphenol increases expressionEXP 6480464bisphenol S results in increased expression of OR4F53 mRNACTDPMID:33297965
Or4f53Mousebisphenol A increases methylationEXP 6480464bisphenol A results in increased methylation of OR4F53 promoterCTDPMID:27312807
Or4f53Mousebisphenol A decreases methylationEXP 6480464bisphenol A results in decreased methylation of OR4F53 promoterCTDPMID:27312807
Or4f53Mousepotassium dichromate increases expressionEXP 6480464Potassium Dichromate results in increased expression of OR4F53 mRNACTDPMID:23608068
Or4f53Mousetitanium dioxide decreases expressionEXP 6480464titanium dioxide results in decreased expression of OR4F53 mRNACTDPMID:29264374


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or4f53MouseG protein-coupled receptor signaling pathway acts_upstream_of_or_withinISAprotein_id:AAD051952290270 PMID:14611657MGIPMID:14611657
Or4f53Mousesensory perception of smell acts_upstream_of_or_withinISAprotein_id:AAD051952290270 PMID:14611657MGIPMID:14611657

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or4f53Mousemembrane located_inISAprotein_id:AAD051952290270 PMID:14611657MGIPMID:14611657

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or4f53Mouseolfactory receptor activity enablesIBAPANTHER:PTN001239295 more ...2290270 GO_CentralGO_REF:0000033
Or4f53Mouseolfactory receptor activity enablesISAprotein_id:AAD051952290270 PMID:14611657MGIPMID:14611657


#
Reference Title
Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:11802173   PMID:11875048   PMID:14611657   PMID:19474196   PMID:21873635   PMID:32295537  



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Variants in Or4f53
21 total Variants

Predicted Target Of
Summary Value
Count of predictions:60
Count of miRNA genes:59
Interacting mature miRNAs:60
Transcripts:ENSMUST00000073322
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 50 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
1301909Smdq2_msegregation of mitochondrial DNA QTL 2 (mouse)Not determined292778465126778607Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
11532731Sluc31a_msusceptibility to lung cancer 31a (mouse)288015003122015170Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260520612119355518Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse

1 to 10 of 50 rows
UniSTS:485086  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382111,257,117 - 111,258,055UniSTSGRCm38
MGSCv372111,097,274 - 111,098,212UniSTSGRCm37
Celera2112,413,280 - 112,414,218UniSTS
Cytogenetic Map2E3UniSTS
UniSTS:495594  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382111,257,038 - 111,258,086UniSTSGRCm38
MGSCv372111,097,195 - 111,098,243UniSTSGRCm37
Celera2112,413,201 - 112,414,249UniSTS
Cytogenetic Map2E3UniSTS







Ensembl Acc Id: ENSMUST00000073322   ⟹   ENSMUSP00000073046
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2111,087,462 - 111,088,400 (+)Ensembl
GRCm38.p6 Ensembl2111,257,117 - 111,258,055 (+)Ensembl
Ensembl Acc Id: ENSMUST00000213658
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2111,084,861 - 111,092,371 (+)Ensembl
GRCm38.p6 Ensembl2111,254,516 - 111,262,026 (+)Ensembl
Ensembl Acc Id: ENSMUST00000218065   ⟹   ENSMUSP00000151987
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2111,084,861 - 111,092,371 (+)Ensembl
GRCm38.p6 Ensembl2111,254,516 - 111,262,026 (+)Ensembl
RefSeq Acc Id: NM_146395   ⟹   NP_666507
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392111,087,462 - 111,088,400 (+)NCBI
GRCm382111,257,117 - 111,258,055 (+)ENTREZGENE
MGSCv372111,097,274 - 111,098,212 (+)RGD
Celera2112,413,280 - 112,414,218 (+)RGD
cM Map2 ENTREZGENE
Sequence:
Protein RefSeqs NP_666507 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAL61363 (Get FASTA)   NCBI Sequence Viewer  
  AAP71670 (Get FASTA)   NCBI Sequence Viewer  
  EDL27803 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000073046
  ENSMUSP00000073046.2
  ENSMUSP00000151987.2
RefSeq Acc Id: NP_666507   ⟸   NM_146395
- UniProtKB: Q8VF40 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000151987   ⟸   ENSMUST00000218065
Ensembl Acc Id: ENSMUSP00000073046   ⟸   ENSMUST00000073322
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VF40-F1-model_v2 AlphaFold Q8VF40 1-312 view protein structure



1 to 21 of 21 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000063844 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000073322 ENTREZGENE
  ENSMUST00000073322.2 UniProtKB/TrEMBL
  ENSMUST00000218065.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfactory_Receptors UniProtKB/TrEMBL
KEGG Report mmu:258390 UniProtKB/TrEMBL
MGD MGI:3031110 ENTREZGENE
NCBI Gene 258390 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or4f53 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt Q8VF40 ENTREZGENE, UniProtKB/TrEMBL
1 to 21 of 21 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or4f53  olfactory receptor family 4 subfamily F member 53  Olfr1276  olfactory receptor 1276  Symbol and/or name change 5135510 APPROVED