Or6f2 (olfactory receptor family 6 subfamily F member 2) - Rat Genome Database

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Gene: Or6f2 (olfactory receptor family 6 subfamily F member 2) Mus musculus
Analyze
No known orthologs.
Symbol: Or6f2
Name: olfactory receptor family 6 subfamily F member 2
RGD ID: 1550629
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GA_x6K02T2PBJ9-42327937-42328872; MOR104; MOR104-4; odorant receptor; olfactory receptor 523; olfactory receptor MOR104-4; Olfr523
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397139,756,017 - 139,756,970 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7139,753,130 - 139,758,671 (+)EnsemblGRCm39 Ensembl
GRCm387140,176,104 - 140,177,057 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7140,173,217 - 140,178,758 (+)EnsemblGRCm38mm10GRCm38
MGSCv377147,362,003 - 147,362,956 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367140,027,424 - 140,028,377 (+)NCBIMGSCv36mm8
Celera7139,974,223 - 139,975,176 (+)NCBICelera
Cytogenetic Map7F4NCBI
cM Map785.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11014824   PMID:11802173   PMID:11875048   PMID:12477932   PMID:14611657   PMID:21267068   PMID:21873635   PMID:32295537  


Genomics

Variants

.
Variants in Or6f2
39 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:244
Count of miRNA genes:230
Interacting mature miRNAs:244
Transcripts:ENSMUST00000055890
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
11059562Lmr21b_mleishmaniasis resistance 21b (mouse)7110967235144967336Mouse
1302032Alcp12_malcohol preference locus 12 (mouse)Not determined7111166122144995196Mouse
1301590Pbwg3_mpostnatal body weight growth 3 (mouse)Not determined7127311241144995196Mouse
1300566Sluc8_msusceptibility to lung cancer 8 (mouse)Not determined7127398151144995196Mouse
14700684Civq1_mcerebral infarct volume QTL 1 (mouse)7109707335143707335Mouse
1300670Sluc19_msusceptibility to lung cancer 19 (mouse)Not determined7111166122144995196Mouse
14746988Manh63_mmandible shape 63 (mouse)7127735437144995196Mouse
14700687Civq5_mcerebral infarct volume QTL 5 (mouse)7109707335143707335Mouse
14700688Civq6_mcerebral infarct volume QTL 6 (mouse)7109707335143707335Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
4142444Femwf5_mfemur work to failure 5 (mouse)Not determined112552248144995196Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
1300677Bmd9_mbone mineral density 9 (mouse)Not determined7116634089144995196Mouse
1300747Skts2_mskin tumor susceptibility 2 (mouse)Not determined7112922733144995196Mouse
1301898Alcp14_malcohol preference locus 14 (mouse)Not determined7111166122144995196Mouse
1357711Adbg1_madult body growth 1 (mouse)Not determined7118693381144398314Mouse
10402499Lmr21_mleishmaniasis resistance 21 (mouse)Not determined7110967235144967336Mouse
1301773Stheal7_msoft tissue heal 7 (mouse)Not determined7119132573144995196Mouse

Markers in Region
UniSTS:494967  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387140,176,061 - 140,177,116UniSTSGRCm38
MGSCv377147,361,960 - 147,363,015UniSTSGRCm37
Celera7139,974,180 - 139,975,235UniSTS
Cytogenetic Map7F4UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000055890   ⟹   ENSMUSP00000052678
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7139,755,974 - 139,757,029 (+)Ensembl
GRCm38.p6 Ensembl7140,176,061 - 140,177,116 (+)Ensembl
Ensembl Acc Id: ENSMUST00000209314   ⟹   ENSMUSP00000148025
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7139,753,130 - 139,758,671 (+)Ensembl
GRCm38.p6 Ensembl7140,173,217 - 140,178,758 (+)Ensembl
Ensembl Acc Id: ENSMUST00000213953   ⟹   ENSMUSP00000149510
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7139,753,130 - 139,758,671 (+)Ensembl
GRCm38.p6 Ensembl7140,173,217 - 140,178,758 (+)Ensembl
Ensembl Acc Id: ENSMUST00000214272   ⟹   ENSMUSP00000150614
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7139,753,148 - 139,758,671 (+)Ensembl
GRCm38.p6 Ensembl7140,173,235 - 140,178,758 (+)Ensembl
Ensembl Acc Id: ENSMUST00000215785   ⟹   ENSMUSP00000149490
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7139,753,148 - 139,758,671 (+)Ensembl
GRCm38.p6 Ensembl7140,173,235 - 140,178,758 (+)Ensembl
Ensembl Acc Id: ENSMUST00000216023   ⟹   ENSMUSP00000149562
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7139,753,148 - 139,758,671 (+)Ensembl
GRCm38.p6 Ensembl7140,173,235 - 140,178,758 (+)Ensembl
RefSeq Acc Id: NM_146518   ⟹   NP_666729
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397139,756,017 - 139,756,970 (+)NCBI
GRCm387140,176,104 - 140,177,057 (+)ENTREZGENE
MGSCv377147,362,003 - 147,362,956 (+)RGD
Celera7139,974,223 - 139,975,176 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_666729   ⟸   NM_146518
- UniProtKB: Q8VFE7 (UniProtKB/TrEMBL),   Q7TRU1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000149510   ⟸   ENSMUST00000213953
Ensembl Acc Id: ENSMUSP00000052678   ⟸   ENSMUST00000055890
Ensembl Acc Id: ENSMUSP00000149562   ⟸   ENSMUST00000216023
Ensembl Acc Id: ENSMUSP00000149490   ⟸   ENSMUST00000215785
Ensembl Acc Id: ENSMUSP00000148025   ⟸   ENSMUST00000209314
Ensembl Acc Id: ENSMUSP00000150614   ⟸   ENSMUST00000214272
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VFE7-F1-model_v2 AlphaFold Q8VFE7 1-317 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3030357 AgrOrtholog
Ensembl Genes ENSMUSG00000051051 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000055890 ENTREZGENE
  ENSMUST00000055890.6 UniProtKB/TrEMBL
  ENSMUST00000209314.3 UniProtKB/TrEMBL
  ENSMUST00000213953.2 UniProtKB/TrEMBL
  ENSMUST00000214272.2 UniProtKB/TrEMBL
  ENSMUST00000215785.2 UniProtKB/TrEMBL
  ENSMUST00000216023.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfact_rcpt_6C-like UniProtKB/TrEMBL
KEGG Report mmu:258511 UniProtKB/TrEMBL
MGD MGI:3030357 ENTREZGENE
NCBI Gene 258511 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or6f2 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt Q7TRU1 ENTREZGENE, UniProtKB/TrEMBL
  Q8VFE7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or6f2  olfactory receptor family 6 subfamily F member 2  Olfr523  olfactory receptor 523  Symbol and/or name change 5135510 APPROVED